Calcium upregulation by percutaneous administration of gene therapy in patients with cardiac disease (CUPID 2): a randomised, multinational, double-blind, placebo-controlled, phase 2b trial

Authors: Greenberg, Barry, Butler, Javed, Felker, G Michael, Ponikowski, Piotr, Voors, Adriaan A, Desai, Akshay S, Barnard, Denise, Bouchard, Alain, Jaski, Brian, Lyon, Alexander R, Pogoda, Janice M, Rudy, Jeffrey J, Zsebo, Krisztina M

Source: In The Lancet 19-25 March 2016 387(10024):1178-1186

Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders

Authors: Kang, Soojeong, Dahl, Russell, Hsieh, Wilson, Shin, Andrew, Zsebo, Krisztina M., Buettner, Christoph, Hajjar, Roger J., Lebeche, Djamel

Source: In Journal of Biological Chemistry 4 March 2016 291(10):5185-5198

Discovery of Enzyme Modulators via High-Throughput Time-Resolved FRET in Living Cells

Authors: Gruber, Simon J., Cornea, Razvan L., Li, Ji, Peterson, Kurt C., Schaaf, Tory M., Gillispie, Gregory D., Dahl, Russell, Zsebo, Krisztina M., Robia, Seth L., Thomas, David D. ^*

Source: In SLAS Discovery February 2014 19(2):215-222

Design of a Phase 2b Trial of Intracoronary Administration of AAV1/SERCA2a in Patients With Advanced Heart Failure: The CUPID 2 Trial (Calcium Up-Regulation by Percutaneous Administration of Gene Therapy in Cardiac Disease Phase 2b)

Authors: Greenberg, Barry, Yaroshinsky, Alex, Zsebo, Krisztina M., Butler, Javed, Felker, G. Michael, Voors, Adriaan A., Rudy, Jeffrey J., Wagner, Kim, Hajjar, Roger J.

Source: In JACC: Heart Failure February 2014 2(1):84-92

High-Throughput FRET Assay Yields Allosteric SERCA Activators

Authors: Cornea, Razvan L., Gruber, Simon J., Lockamy, Elizabeth L., Muretta, Joseph M., Jin, Dongzhu, Chen, Jiqiu, Dahl, Russell, Bartfai, Tamas, Zsebo, Krisztina M., Gillispie, Gregory D., Thomas, David D. ^*

Source: In SLAS Discovery January 2013 18(1):97-107

Stem Cell Factor Gene Transfer Improves Cardiac Function After Myocardial Infarction in Swine

Authors: Ishikawa, Kiyotake, Fish, Kenneth, Aguero, Jaume, Yaniz-Galende, Elisa, Jeong, Dongtak, Kho, Changwon, Tilemann, Lisa, Fish, Lauren, Liang, Lifan, Eltoukhy, Ahmed A., Anderson, Daniel G., Zsebo, Krisztina, Costa, Kevin D., Hajjar, Roger J.

Source: Circulation.Heart failure. 8(1):167-174

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100052367444.0x000001&indx=1&recIds=ETOCvdc_100052367444.0x000001

Concomitant Intravenous Nitroglycerin With Intracoronary Delivery of AAV1.SERCA2a Enhances Gene Transfer in Porcine Hearts

Authors: Karakikes, Ioannis, Hadri, Lahouaria, Rapti, Kleopatra, Ladage, Dennis, Ishikawa, Kiyotake, Tilemann, Lisa, Yi, Geng-Hua, Morel, Charlotte, Gwathmey, Judith K, Zsebo, Krisztina, Weber, Thomas, Kawase, Yoshiaki, Hajjar, Roger J

Source: In Molecular Therapy March 2012 20(3):565-571

Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID Trial), a First-in-Human Phase 1/2 Clinical Trial

Authors: Jaski, Brian E., Jessup, Mariell L., Mancini, Donna M., Cappola, Thomas P., Pauly, Daniel F., Greenberg, Barry, Borow, Kenneth, Dittrich, Howard, Zsebo, Krisztina M., Hajjar, Roger J.

Source: In Journal of Cardiac Failure 2009 15(3):171-181

Recombinant Human Granulocyte Colony-Stimulating Factor: Effects on Normal and Leukemic Myeloid Cells

Authors: Souza, Lawrence M., Boone, Thomas C., Gabrilove, Janice, Lai, Por H., Zsebo, Krisztina M., Murdock, Douglas C., Chazin, Vicki R., Bruszewski, Joan, Lu, Hsieng, Chen, Kenneth K., Barendt, Jean, Platzer, Erich, Mertelsmann, Roland, Welte, Karl

Source: Science, 1986 Apr 01. 232(4746), 61-65.

Access URL: https://www.jstor.org/stable/1697039

Induction of Mast Cell Proliferation, Maturation, and Heparin Synthesis by the Rat c-Kit Ligand, Stem Cell Factor

Authors: Tsai, Mindy, Takeishi, Takashi, Thompson, Helen, Langley, Keith E., Zsebo, Krisztina M., Metcalfe, Dean D., Geissler, Edwin N., Galli, Stephen J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1991 Jul . 88(14), 6382-6386.

Access URL: https://www.jstor.org/stable/2357503

In vivo Stimulation of Granulopoiesis by Recombinant Human Granulocyte Colony-Stimulating Factor

Authors: Cohen, Arthur M., Zsebo, Krisztina M., Inoue, Hideo, Hines, Dawn, Boone, Thomas C., Chazin, Vicki R., Tsai, Lawrence, Ritch, Thomas, Souza, Lawrence M.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1987 Apr . 84(8), 2484-2488.

Access URL: https://www.jstor.org/stable/29738

Stem Cell Factor Induces Proliferation and Differentiation of Highly Enriched Murine Hematopoietic Cells

Authors: Migliaccio, Giovanni, Migliaccio, Anna Rita, Valinsky, Jay, Langley, Keith, Zsebo, Krisztina, Adamson, John W.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1991 Aug . 88(16), 7420-7424.

Access URL: https://www.jstor.org/stable/2357695

Support of Human Hematopoisis in Long-Term Bone Marrow Cultures by Murin Stromal Cells Selectively Expressing the Membrane-Bound and Secreted Forms of the Human Homolog of the Steel Gene Product, Stem Cell Factor

Authors: Toksoz, Deniz, Zsebo, Krisztina M., Smith, Kent A., Hu, Sylvia, Brankow, David, Suggs, Sydney V., Martin, Francis H., William, David A.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1992 Aug . 89(16), 7350-7354.

Access URL: https://www.jstor.org/stable/2360087

Radioprotection of Mice by Recombinant Rat Stem Cell Factor

Authors: Zsebo, Krisztina M., Smith, Kent A., Hartley, Cynthia A., Greenblatt, Melvin, Cooke, Keegan, Rich, William, McNiece, Ian K.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1992 Oct . 89(20), 9464-9468.

Access URL: https://www.jstor.org/stable/2360421

Development of Human Mast Cells From Umbilical Cord Blood Cells by Recombinant Human and Murine c-kit Ligand

Authors: Mitsui, Hideki, Furitsu, Takuma, Dvorak, Ann M., Irani, Anne-Marie A., Schwartz, Lawrence B., Inagaki, Naoki, Takei, Masao, Ishizaka, Kimishige, Zsebo, Krisztina M., Gillis, Steven, Ishizaka, Teruko

Source: Proceedings of the National Academy of Sciences of the United States of America, 1993 Jan . 90(2), 735-739.

Access URL: https://www.jstor.org/stable/2361132

Design of a Phase 1/2 Trial of Intracoronary Administration of AAV1/SERCA2a in Patients With Heart Failure

Authors: Hajjar, Roger J., Zsebo, Krisztina, Deckelbaum, Lawrence, Thompson, Craig, Rudy, Jeff, Yaroshinsky, Alex, Ly, Hung, Kawase, Yoshiaki, Wagner, Kim, Borow, Kenneth, Jaski, Brian, London, Barry, Greenberg, Barry, Pauly, Daniel F., Patten, Richard, Starling, Randall, Mancini, Donna, Jessup, Mariell

Source: In Journal of Cardiac Failure 2008 14(5):355-367

Method for enhanced uptake of viral vectors in the myocardium

Restoration of mechanical and energetic function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins

Authors: Sakata, Susumu, Lebeche, Djamel, Sakata, Naoya, Sakata, Yuri, Chemaly, Elie R., Liang, Li Fan, Tsuji, Tsuyoshi, Takewa, Yoshiaki, del Monte, Federica, Peluso, Richard, Zsebo, Krisztina, Jeong, Dongtak, Park, Woo Jin, Kawase, Yoshiaki, Hajjar, Roger J.

Source: In Journal of Molecular and Cellular Cardiology 2007 42(4):852-861

Method for enhanced uptake of viral vectors in the myocardium

FLUORESCENCE RESONANCE ENERGY TRANSFER ASSAYS FOR SARCO/ENDOPLASMIC RETICULUM CALCIUM ATPASE AND PHOSPHOLAMBAN