Electron spin dynamics guide cell motility

Authors: Wang, Kai, Gilmer, Gabrielle, Arana, Matheus Candia, Iijima, Hirotaka, Bergmann, Juliana, Woollard, Antonio, Mesits, Boris, McGraw, Meghan, Zoltowski, Brian, Cappellaro, Paola, Ungar, Alex, Pekker, David, Waldeck, David H., Saxena, Sunil, Lloyd, Seth, Ambrosio, Fabrisia

Subject Terms: Physics - Biological Physics, Quantitative Biology - Cell Behavior, Quantum Physics

Access URL: http://arxiv.org/abs/2503.02923

Allosteric control of ACE2 peptidase domain dynamicsElectronic supplementary information (ESI) available: Tables S1–S4; machine learning model regularization; Fig. S1–S7. See DOI: https://doi.org/10.1039/d2ob00606e

Authors: Trozzi, Francesco, Karki, Nischal, Song, Zilin, Verma, Niraj, Kraka, Elfi, Zoltowski, Brian D., Tao, Peng

Source: Organic & biomolecular chemistry. 20(17):3605-3618

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100148664480.0x000001&indx=1&recIds=ETOCvdc_100148664480.0x000001

Steric and Electronic Interactions at Gln154 in ZEITLUPE Induce Reorganization of the LOV Domain Dimer Interface

Authors: Pudasaini, Ashutosh, Green, Robert, Song, Young Hun, Blumenfeld, Abby, Karki, Nischal, Imaizumi, Takato, Zoltowski, Brian D.

Source: Biochemistry. 60(2):95-103

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN625696937&indx=1&recIds=ETOCRN625696937

Cryptochromes: Photochemical and structural insight into magnetoreception

Authors: Karki, Nischal, Vergish, Satyam, Zoltowski, Brian D.

Source: Protein science. 30(8):1521-1534

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100123673154.0x000001&indx=1&recIds=ETOCvdc_100123673154.0x000001

Chemical and structural analysis of a photoactive vertebrate cryptochrome from pigeon

Authors: Zoltowski, Brian D., Chelliah, Yogarany, Wickramaratne, Anushka, Jarocha, Lauren, Karki, Nischal, Xu, Wei, Mouritsen, Henrik, Hore, Peter J., Hibbs, Ryan E., Green, Carla B., Takahashi, Joseph S.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Sep . 116(39), 19449-19457.

Access URL: https://www.jstor.org/stable/26855185

A structural decryption of cryptochromes.

Authors: DeOliveira, Cristina C., Crane, Brian R., Zoltowski, Brian D., Lin, Chentao

Source: Frontiers in Chemistry; 2024, p1-18, 18p

Subject Terms: CRYPTOCHROMES, MOLECULAR structure, CHEMICAL properties, SMALL molecules, POST-translational modification

β‐sheets mediate the conformational change and allosteric signal transmission between the AsLOV2 termini.

Authors: Xiao, Sian¹, sxiao@smu.edu, Ibrahim, Mayar Tarek¹, Verkhivker, Gennady M.², Zoltowski, Brian D.¹, Tao, Peng¹, ptao@smu.edu

Source: Journal of Computational Chemistry; 6/30/2024, Vol. 45 Issue 17, p1493-1504, 12p

Disrupting FKF1 homodimerization increases FT transcript levels in the evening by enhancing CO stabilization.

Authors: Cho, Sung Won, Lokhandwala, Jameela, Park, Jun Sang, Kang, Hye Won, Choi, Mingi, Yang, Hong-Quan, Imaizumi, Takato, Zoltowski, Brian D., Song, Young Hun

Source: Plant Cell Reports; May2024, Vol. 43 Issue 5, p1-12, 12p

A Native Threonine Coordinates Ordered Water to Tune Light-Oxygen-Voltage (LOV) Domain Photocycle Kinetics and Osmotic Stress Signaling in Trichoderma reesei ENVOY

Authors: Lokhandwala, Jameela, Silverman y de la Vega, Rafael I., Hopkins, Hilary C., Britton, Collin W., Rodriguez-Iglesias, Aroa, Bogomolni, Roberto, Schmoll, Monika, Zoltowski, Brian D.

Source: In Journal of Biological Chemistry 8 July 2016 291(28):14839-14850

Resolving cryptic aspects of cryptochrome signaling

Authors: Zoltowski, Brian D.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2015 Jul . 112(29), 8811-8812.

Access URL: https://www.jstor.org/stable/26466069

Structural Biochemistry of a Fungal LOV Domain Photoreceptor Reveals an Evolutionarily Conserved Pathway Integrating Light and Oxidative Stress

Authors: Lokhandwala, Jameela, Hopkins, Hilary C., Rodriguez-Iglesias, Aroa, Dattenböck, Christoph, Schmoll, Monika, Zoltowski, Brian D.

Source: In Structure 6 January 2015 23(1):116-125

Conformational Switching in the Fungal Light Sensor Vivid

Authors: Zoltowski, Brian D., Schwerdtfeger, Carsten, Widom, Joanne, Loros, Jennifer J., Bilwes, Alexandrine M., Dunlap, Jay C., Crane, Brian R.

Source: Science, 2007 May . 316(5827), 1054-1057.

Access URL: https://www.jstor.org/stable/20036292

Illuminating Solution Responses of a LOV Domain Protein with Photocoupled Small-Angle X-Ray Scattering

Authors: Lamb, Jessica S., Zoltowski, Brian D., Pabit, Suzette A., Li, Li, Crane, Brian R., Pollack, Lois

Source: In Journal of Molecular Biology 6 November 2009 393(4):909-919

Allosteric regulation in STAT3 interdomains is mediated by a rigid core: SH2 domain regulation by CCD in D170A variant.

Authors: Zhao, Tingting, Karki, Nischal, Zoltowski, Brian D., Matthews, Devin A.

Source: PLoS Computational Biology; 12/21/2022, Vol. 18 Issue 12, p1-21, 21p, 3 Diagrams, 1 Chart, 2 Graphs

Subject Terms: ALLOSTERIC regulation, STAT proteins, MOLECULAR dynamics, DRUG discovery, DRUG design, PROTEIN domains

Company/Entity: UNITED States. Food & Drug Administration

Structure of full-length Drosophila cryptochrome.

Authors: Zoltowski, Brian D., Vaidya, Anand T., Top, Deniz

Source: Nature; December 15 2011, Vol. 480 Issue 7377, p396-399, 4p

Variations in Protein-Flavin Hydrogen Bonding in a Light, Oxygen, Voltage Domain Produce Non-Arrhenius Kinetics of Adduct Decay.

Authors: Zoltowski, Brian D., Nash, Abigail I., Gardner, Kevin H.

Source: Biochemistry; October 18 2011, Vol. 50 Issue 41, p8771-8779, 9p

Tripping the Light Fantastic: Blue-Light Photoreceptors as Examples of Environmentally Modulated Protein-Protein Interactions.

Authors: Zoltowski, Brian D., Gardner, Kevin H.

Source: Biochemistry; January 11 2011, Vol. 50 Issue 1, p4-16, 13p

Light Activation of the LOV Protein Vivid Generates a Rapidly Exchanging Dimer.

Authors: Zoltowski, Brian D., Crane, Brian R.

Source: Biochemistry; July 8 2008, Vol. 47 Issue 27, p7012-7019, 8p

Dimeric allostery mechanism of the plant circadian clock photoreceptor ZEITLUPE.

Authors: Trozzi, Francesco, Wang, Feng, Verkhivker, Gennady, Zoltowski, Brian D., Tao, Peng

Source: PLoS Computational Biology; 7/26/2021, Vol. 17 Issue 7, p1-29, 29p, 1 Diagram, 1 Chart, 8 Graphs

Subject Terms: ARABIDOPSIS proteins, ALLOSTERIC regulation, PHOTORECEPTORS, SUPERVISED learning, PLANT development, LIGHT absorption

Mechanism-based tuning of a LOV domain photoreceptor.

Authors: Zoltowski, Brian D.¹, Vaccaro, Brian¹, Crane, Brian R.¹ bc69@cornell.edu

Source: Nature Chemical Biology. Nov2009, Vol. 5 Issue 11, p827-834. 8p. 2 Diagrams, 1 Chart, 3 Graphs.

Subject Terms: *PROTEIN structure, *PROTEIN-protein interactions, *BIOMOLECULES, *CYSTEINE proteinases, *PHOTORECEPTORS, *MOLECULAR probes