Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic male infertility in human and mouse

Authors: Jana Muroňová, Zine Eddine Kherraf, Elsa Giordani, Emeline Lambert, Simon Eckert, Caroline Cazin, Amir Amiri-Yekta, Magali Court, Geneviève Chevalier, Guillaume Martinez, Yasmine Neirijnck, Francoise Kühne, Lydia Wehrli, Nikolai Klena, Virginie Hamel, Lisa De Macedo, Jessica Escoffier, Paul Guichard, Charles Coutton, Selima Fourati Ben Mustapha, Mahmoud Kharouf, Anne-Pacale Bouin, Raoudha Zouari, Nicolas Thierry-Mieg, Serge Nef, Stefan Geimer, Corinne Loeuillet, Pierre F Ray, Christophe Arnoult

Source: eLife, Vol 12 (2024)

Subject Terms: infertility, sperm, flagellum, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/86845; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/078af173188c4adb858332ae057a3a05

Novel axonemal protein ZMYND12 interacts with TTC29 and DNAH1, and is required for male fertility and flagellum function

Authors: Denis Dacheux, Guillaume Martinez, Christine E Broster Reix, Julie Beurois, Patrick Lores, Magamba Tounkara, Jean-William Dupuy, Derrick Roy Robinson, Corinne Loeuillet, Emeline Lambert, Zeina Wehbe, Jessica Escoffier, Amir Amiri-Yekta, Abbas Daneshipour, Seyedeh-Hanieh Hosseini, Raoudha Zouari, Selima Fourati Ben Mustapha, Lazhar Halouani, Xiaohui Jiang, Ying Shen, Chunyu Liu, Nicolas Thierry-Mieg, Amandine Septier, Marie Bidart, Véronique Satre, Caroline Cazin, Zine Eddine Kherraf, Christophe Arnoult, Pierre F Ray, Aminata Toure, Mélanie Bonhivers, Charles Coutton

Source: eLife, Vol 12 (2023)

Subject Terms: Trypanosoma brucei, male infertility, asthenoteratozoospermia, sperm flagellum, DNAH1, TTC29, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/87698; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/2b37a6175cab4e93a36110639ca35769

Identification of IQCH as a calmodulin-associated protein required for sperm motility in humans

Authors: Emma Cavarocchi, Camille Sayou, Patrick Lorès, Caroline Cazin, Laurence Stouvenel, Elma El Khouri, Charles Coutton, Zine-Eddine Kherraf, Catherine Patrat, Jérôme Govin, Nicolas Thierry-Mieg, Marjorie Whitfield, Pierre F. Ray, Emmanuel Dulioust, Aminata Touré

Source: iScience, Vol 26, Iss 8, Pp 107354- (2023)

Subject Terms: Health sciences, Clinical genetics, Cell biology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004223014311; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/4849c1c8f2ce49cba28ea421e079c4d2

From azoospermia to macrozoospermia, a phenotypic continuum due to mutations in the ZMYND15 gene

Authors: Zine-Eddine Kherraf, Caroline Cazin, Florence Lestrade, Jana Muronova, Charles Coutton, Christophe Arnoult, Nicolas Thierry-Mieg, Pierre F Ray

Source: Asian Journal of Andrology, Vol 24, Iss 3, Pp 243-247 (2022)

Subject Terms: azoospermia, gene defect, macrozoospermia, male infertility, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://www.ajandrology.com/article.asp?issn=1008-682X;year=2022;volume=24;issue=3;spage=243;epage=247;aulast=Kherraf; https://doaj.org/toc/1008-682X; https://doaj.org/toc/1745-7262

Access URL: https://doaj.org/article/485e1c403e484be88b93b73aab4bab74

Oligogenic heterozygous inheritance of sperm abnormalities in mouse

Authors: Guillaume Martinez, Charles Coutton, Corinne Loeuillet, Caroline Cazin, Jana Muroňová, Magalie Boguenet, Emeline Lambert, Magali Dhellemmes, Geneviève Chevalier, Jean-Pascal Hograindleur, Charline Vilpreux, Yasmine Neirijnck, Zine-Eddine Kherraf, Jessica Escoffier, Serge Nef, Pierre F Ray, Christophe Arnoult

Source: eLife, Vol 11 (2022)

Subject Terms: infertility, oligogenism, heredity, sperm abnormalities, MMAF, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/75373; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/50542f6b588b43b1b940b0989e0ff1de

Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human

Authors: Charles Coutton, Alexandra S. Vargas, Amir Amiri-Yekta, Zine-Eddine Kherraf, Selima Fourati Ben Mustapha, Pauline Le Tanno, Clémentine Wambergue-Legrand, Thomas Karaouzène, Guillaume Martinez, Serge Crouzy, Abbas Daneshipour, Seyedeh Hanieh Hosseini, Valérie Mitchell, Lazhar Halouani, Ouafi Marrakchi, Mounir Makni, Habib Latrous, Mahmoud Kharouf, Jean-François Deleuze, Anne Boland, Sylviane Hennebicq, Véronique Satre, Pierre-Simon Jouk, Nicolas Thierry-Mieg, Beatrice Conne, Denis Dacheux, Nicolas Landrein, Alain Schmitt, Laurence Stouvenel, Patrick Lorès, Elma El Khouri, Serge P. Bottari, Julien Fauré, Jean-Philippe Wolf, Karin Pernet-Gallay, Jessica Escoffier, Hamid Gourabi, Derrick R. Robinson, Serge Nef, Emmanuel Dulioust, Raoudha Zouari, Mélanie Bonhivers, Aminata Touré, Christophe Arnoult, Pierre F. Ray

Source: Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/03b883f351d94cb6999191bf43221e62

Biallelic mutations in CFAP65 cause male infertility with multiple morphological abnormalities of the sperm flagella in humans and mice.

Authors: Weiyu Li, Huan Wu, Fuping Li, Shixiong Tian, Zine-Eddine Kherraf, Jintao Zhang, Xiaoqing Ni, Mingrong Lv, Chunyu Liu, Qing Tan, Ying Shen, Amiri-Yekta, Amir, Cazin, Caroline, Jingjing Zhang, Wangjie Liu, Yan Zheng, Huiru Cheng, Yingbi Wu, Jiajia Wang, Yang Gao

Source: Journal of Medical Genetics; Feb2020, Vol. 57 Issue 2, p89-95, 7p

PATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice

Authors: Marie Christou‐Kent, Zine‐Eddine Kherraf, Amir Amiri‐Yekta, Emilie Le Blévec, Thomas Karaouzène, Béatrice Conne, Jessica Escoffier, Said Assou, Audrey Guttin, Emeline Lambert, Guillaume Martinez, Magalie Boguenet, Selima Fourati Ben Mustapha, Isabelle Cedrin Durnerin, Lazhar Halouani, Ouafi Marrakchi, Mounir Makni, Habib Latrous, Mahmoud Kharouf, Charles Coutton, Nicolas Thierry‐Mieg, Serge Nef, Serge P Bottari, Raoudha Zouari, Jean Paul Issartel, Pierre F Ray, Christophe Arnoult

Source: EMBO Molecular Medicine, Vol 10, Iss 5, Pp 1-24 (2018)

Subject Terms: female sterility, oocyte developmental competence, oocyte maturation arrest, oocyte maturation failure, Patl2, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/2a2704a3d4124064a7b9b19a154a9916

Combined Use of Whole Exome Sequencing and CRISPR/Cas9 to Study the Etiology of Non-Obstructive Azoospermia: Demonstration of the Dispensable Role of the Testis-Specific Genes C1orf185 and CCT6B

Authors: Caroline Cazin, Yasmine Neirijnck, Corinne Loeuillet, Lydia Wehrli, Françoise Kühne, Isabelle Lordey, Selima Fourati Ben Mustapha, Amin Bouker, Raoudha Zouari, Nicolas Thierry-Mieg, Serge Nef, Christophe Arnoult, Pierre F. Ray, Zine-Eddine Kherraf

Source: Cells, Vol 11, Iss 1, p 118 (2021)

Subject Terms: spermatogenesis, non-obstructive azoospermia, genetics of male infertility, whole exome sequencing, CRISPR/Cas9, C1orf185, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/1/118; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/cefaab1e590541ddbadfb7cc15ec9d6a

SPINK2 deficiency causes infertility by inducing sperm defects in heterozygotes and azoospermia in homozygotes

Authors: Zine‐Eddine Kherraf, Marie Christou‐Kent, Thomas Karaouzene, Amir Amiri‐Yekta, Guillaume Martinez, Alexandra S Vargas, Emeline Lambert, Christelle Borel, Béatrice Dorphin, Isabelle Aknin‐Seifer, Michael J Mitchell, Catherine Metzler‐Guillemain, Jessica Escoffier, Serge Nef, Mariane Grepillat, Nicolas Thierry‐Mieg, Véronique Satre, Marc Bailly, Florence Boitrelle, Karin Pernet‐Gallay, Sylviane Hennebicq, Julien Fauré, Serge P Bottari, Charles Coutton, Pierre F Ray, Christophe Arnoult

Source: EMBO Molecular Medicine, Vol 9, Iss 8, Pp 1132-1149 (2017)

Subject Terms: azoospermia, exome sequencing, genetics, infertility, spermatogenesis, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/acfdace776ce4e4b925803c814b43c54