Targeted long-read sequencing enables higher diagnostic yield of ADPKD by accurate PKD1 genetic analysis

Authors: Qian Sun, Peiwen Xu, Aiping Mao, Sexin Huang, Jie Li, Libao Chen, Jing Li, Haopeng Kan, Ju Huang, Wenkai Ji, Dayong Si, Junhao Yan, Zi-Jiang Chen, Xuan Gao, Yuan Gao

Source: npj Genomic Medicine, Vol 10, Iss 1, Pp 1-11 (2025)

Subject Terms: Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/2056-7944

Access URL: https://doaj.org/article/31d771fdf15c437fa82d7b5265adee71

Association of age at menarche and different causes of infertility: a retrospective study of 7634 women undergoing assisted reproductive technology

Authors: Miaomiao Ban, Jiejing Jiao, Jiayi Zhou, Linlin Cui, Huidan Wang, Zi-Jiang Chen

Source: Journal of Ovarian Research, Vol 18, Iss 1, Pp 1-11 (2025)

Subject Terms: Infertility, Age at menarche, Polycystic ovary syndrome, Endometriosis, Diminished ovarian reserve, Gynecology and obstetrics, RG1-991

File Description: electronic resource

Relation: https://doaj.org/toc/1757-2215

Access URL: https://doaj.org/article/1a5638dabd5b49a2a34006f2df94dd58

Population-level analyses identify host and environmental variables influencing the vaginal microbiome

Authors: Lang Qin, Tianyong Sun, Xiao Li, Shigang Zhao, Zheng Liu, Changlong Zhang, Congcong Jin, Yanqi Xu, Xuan Gao, Yongzhi Cao, Jiaojiao Wang, Ting Han, Lei Yan, Jialun Song, Fangfang Zhang, Feifei Liu, Yousheng Zhang, Yuzhen Huang, Yuping Song, Yanjun Liu, Jing Zhang, Xiuqing Zhang, Zhina Yao, Honglei Chen, Zhenzhen Zhang, Shengrui Zhao, Yuhan Feng, Ya-nan Zhang, Qian Yu, Fang Cao, Lijuan Zhao, Lei Xie, Ling Geng, Qiang Feng, Han Zhao, Zi-Jiang Chen

Source: Signal Transduction and Targeted Therapy, Vol 10, Iss 1, Pp 1-15 (2025)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/44479b77b6c941dab8226a56a9a6efdb

Transgenerational inheritance of diabetes susceptibility in male offspring with maternal androgen exposure

Authors: Yuqing Zhang, Shourui Hu, Shan Han, Congcong Liu, Xiaofan Liang, Yuxuan Li, Zongxuan Lin, Yiming Qin, Chunxuan Geng, Yue Liu, Linlin Cui, Jingmei Hu, Changming Zhang, Zhao Wang, Xin Liu, Jinlong Ma, Zi-Jiang Chen, Han Zhao

Source: Cell Discovery, Vol 11, Iss 1, Pp 1-17 (2025)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2056-5968

Access URL: https://doaj.org/article/2f1965c818774e00a63d668d5485af2f

snRNA-seq of human ovaries reveals heat shock proteins are associated with obesity related cancer risk

Authors: Yuhan Zhang, Yonghui Jiang, Yunhai Yu, Gengchen Feng, Zihe Zhao, Weihan Zhang, Shumin Li, Yimeng Li, Ziyi Yang, Xueqi Yan, Xueying Gao, Zi-Jiang Chen, Han Zhao, Shigang Zhao

Source: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)

Subject Terms: Obesity, Ovary, snRNA-seq, Heat shock proteins, HSPD1, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/1c0e0a8719dc4d02a2ff2094ce1e3490

Altered metabolic profiles in male offspring conceived from intracytoplasmic sperm injection

Authors: Bingqian Zhang, Miaomiao Ban, Xiaojing Chen, Jingmei Hu, Linlin Cui, Zi-Jiang Chen

Source: BMC Medicine, Vol 22, Iss 1, Pp 1-11 (2024)

Subject Terms: Paternal obesity, Intracytoplasmic sperm injection, In vitro fertilization, Metabolic profiles, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/0b40c4072c4c4a37afa479859f2262f8

Effect of single blastocyst-stage versus single cleavage-stage embryo transfer on cumulative live births in women with good prognosis undergoing in vitro fertilization: Multicenter Randomized Controlled Trial

Authors: Xiang Ma, Jing Wang, Yuhua Shi, Jichun Tan, Yichun Guan, Yun Sun, Bo Zhang, Junli Zhao, Jianqiao Liu, Yunxia Cao, Hong Li, Cuilian Zhang, Feng Chen, Honggang Yi, Ze Wang, Xing Xin, Pingping Kong, Yao Lu, Ling Huang, Yingying Yuan, Haiying Liu, Caihua Li, Ben Willem J. Mol, Zhibin Hu, Heping Zhang, Zi-Jiang Chen, Jiayin Liu

Source: Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/99288a173dd242debb104db5141dbb03

Maternal mRNA deadenylation is defective in in vitro matured mouse and human oocytes

Authors: Yusheng Liu, Wenrong Tao, Shuang Wu, Yiwei Zhang, Hu Nie, Zhenzhen Hou, Jingye Zhang, Zhen Yang, Zi-Jiang Chen, Jiaqiang Wang, Falong Lu, Keliang Wu

Source: Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/24e3802812714f3e98aef8506f610122

SHMT2 is essential for mammalian preimplantation embryonic development through de novo biosynthesis of nucleotide metabolites

Authors: Mingze Shi, Yingxue Huai, Tiantian Deng, Chuanxin Zhang, Jinzhu Song, Jiawei Wang, Yiwen Zhang, Zi-Jiang Chen, Han Zhao, Keliang Wu, Boyang Liu

Source: Molecular Therapy: Nucleic Acids, Vol 36, Iss 2, Pp 102499- (2025)

Subject Terms: MT: Oligonucleotides: Therapies and Applications, SHMT2, nucleotide, metabolism, embryo, development, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253125000538; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/5afeeee4fe1e44d8a05a18fd806eb735

Association between being large for gestational age and cardiovascular metabolic health in children conceived from assisted reproductive technology: a prospective cohort study

Authors: Yiyuan Zhang, Kexin Dai, Xiaojing Chen, Linlin Cui, Zi-Jiang Chen

Source: BMC Medicine, Vol 22, Iss 1, Pp 1-12 (2024)

Subject Terms: Large for gestational age, Cardiovascular metabolic health, Obesity, Assisted reproductive technology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/46107abb4b1b43f5935f4e0d67dc408f

TMC7 deficiency causes acrosome biogenesis defects and male infertility in mice

Authors: Jing Wang, Yingying Yin, Lei Yang, Junchao Qin, Zixiang Wang, Chunhong Qiu, Yuan Gao, Gang Lu, Fei Gao, Zi-Jiang Chen, Xiyu Zhang, Hongbin Liu, Zhaojian Liu

Source: eLife, Vol 13 (2024)

Subject Terms: transmembrane channel-like proteins, acrosome biogenesis, spermiogenesis, TMC proteins, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/95888; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/2988ec83d11844a597eef4f541688ec4

CWF19L2 is Essential for Male Fertility and Spermatogenesis by Regulating Alternative Splicing

Authors: Shiyu Wang, Yuling Cai, Tongtong Li, Yan Wang, Ziyou Bao, Renxue Wang, Junchao Qin, Ziqi Wang, Yining Liu, Zhaojian Liu, Wai‐Yee Chan, Xiangfeng Chen, Gang Lu, Zi‐Jiang Chen, Tao Huang, Hongbin Liu

Source: Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)

Subject Terms: CWF19L2, fertility, spermatogenesis, spermatogonial differentiation, splicing factor, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/580dd51ab47e4e0b925cda24115a03f0

MALAT1 expression in granulosa cells in PCOS patients with different phenotypes

Authors: Shumin Li, Yimeng Li, Xueqi Yan, Shigang Zhao, Ziyi Yang, Yuteng Wang, Xueying Gao, Zi-Jiang Chen

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)

Subject Terms: Polycystic ovary syndrome, MALAT1, Long noncoding RNA, Granulosa cells, Metabolism, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/b9cdd057c060419981d0415933f644dc

High-fat and high-sucrose diet impairs female reproduction by altering ovarian transcriptomic and metabolic signatures

Authors: Congcong Liu, Yunde Dou, Mengge Zhang, Shan Han, Shourui Hu, Yuxuan Li, Zhiheng Yu, Yue Liu, Xiaofan Liang, Zi-Jiang Chen, Han Zhao, Yuqing Zhang

Source: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)

Subject Terms: Female reproduction, High-fat and high-sucrose, Polycystic ovary syndrome, Metabolism, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/f3aef4f4e39b4dc0b945809f0ef29e8f

Deconvolution at the single-cell level reveals ovarian cell-type-specific transcriptomic changes in PCOS

Authors: Shumin Li, Yimeng Li, Yu Sun, Gengchen Feng, Ziyi Yang, Xueqi Yan, Xueying Gao, Yonghui Jiang, Yanzhi Du, Shigang Zhao, Han Zhao, Zi-Jiang Chen

Source: Reproductive Biology and Endocrinology, Vol 22, Iss 1, Pp 1-10 (2024)

Subject Terms: Polycystic ovary syndrome, Deconvolution, Granulosa cells, scRNA-seq, Bulk RNA-seq, Gynecology and obstetrics, RG1-991, Reproduction, QH471-489

File Description: electronic resource

Relation: https://doaj.org/toc/1477-7827

Access URL: https://doaj.org/article/ad3447c0004a4d81bb700d4f80101fc1

Fibronectin mediates activin A-promoted human trophoblast migration and acquisition of endothelial-like phenotype

Authors: Xiangxin Lan, Ling Guo, Cuiping Hu, Qian Zhang, Jianye Deng, Yufeng Wang, Zi-Jiang Chen, Junhao Yan, Yan Li

Source: Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)

Subject Terms: Activin A, Fibronectin, Trophoblast, Migration, Endothelial-like tube formation, Pregnancy, Medicine, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1478-811X

Access URL: https://doaj.org/article/79acf96831e74e17aa1cba24610b01ef

Investigation of androgen receptor CAG repeats length in polycystic ovary syndrome diagnosed using the new international evidence-based guideline

Authors: Xueqi Yan, Xueying Gao, Qian Shang, Ziyi Yang, Yuteng Wang, Li Liu, Wei Liu, Dan Liu, Fang Cheng, Shigang Zhao, Han Zhao, Junli Zhao, Zi-Jiang Chen

Source: Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-7 (2023)

Subject Terms: Polycystic ovary syndrome, Polycystic ovarian morphology, Androgen receptor, CAG repeats, Genetic polymorphism, Gynecology and obstetrics, RG1-991

File Description: electronic resource

Relation: https://doaj.org/toc/1757-2215

Access URL: https://doaj.org/article/f692a50bda924a48a77890e8c62bee4e

The deubiquitinase cofactor UAF1 interacts with USP1 and plays an essential role in spermiogenesis

Authors: Ziqi Wang, Tongtong Li, Dongkai Liu, Mengjing Li, Shangming Liu, Xiaochen Yu, Hanzhen Li, Hui Song, Wei Zhao, Zhaojian Liu, Xiangfeng Chen, Gang Lu, Zi-Jiang Chen, Tao Huang, Hongbin Liu

Source: iScience, Vol 27, Iss 4, Pp 109456- (2024)

Subject Terms: Biological sciences, Molecular biology, Molecular interaction, Developmental biology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004224006771; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/537948077c604673b7eb07dd6bd4065b

Identification of novel first-trimester serum biomarkers for early prediction of preeclampsia

Authors: Mingxi Liu, Yue Niu, Kongyang Ma, Peter C. K. Leung, Zi-Jiang Chen, Daimin Wei, Yan Li

Source: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)

Subject Terms: Prediction, Preeclampsia, First trimester, Serum, Biomarker, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/53d4ace247914ccf8f6cd38bc438f4a6

FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells

Authors: Weiwei Xu, Yajuan Yang, Yongze Yu, Canxin Wen, Simin Zhao, Lili Cao, Shidou Zhao, Yingying Qin, Zi-Jiang Chen

Source: BMC Biology, Vol 21, Iss 1, Pp 1-18 (2023)

Subject Terms: Primordial germ cells, FAAP100, Genome stability, Transcription-replication conflicts, R-loop, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7007

Access URL: https://doaj.org/article/90e8480971dc4e52be06e165e4641430