Promotion of Joint Degeneration and Chondrocyte Metabolic Dysfunction by Excessive Growth Hormone in Mice

Authors: Zhu, Shouan, Liu, Huanhuan, Davis, Trent, Willis, Craig R. G., Basu, Reetobrata, Witzigreuter, Luke, Bell, Stephen, Szewczyk, Nathaniel, Lotz, Martin K., Hill, Marcheta, Fajardo, Roberto J., O'Connor, Patrick M., Berryman, Darlene E., Kopchick, John J.

Source: Arthritis & rheumatology. 75(7):1139-1151

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186221338.0x000001&indx=1&recIds=ETOCvdc_100186221338.0x000001

Sirt3 Promotes Chondrogenesis, Chondrocyte Mitochondrial Respiration and the Development of High‐Fat Diet‐Induced Osteoarthritis in Mice

Authors: Zhu, Shouan, Donovan, Elise L., Makosa, Dawid, Mehta‐D'souza, Padmaja, Jopkiewicz, Anita, Batushansky, Albert, Cortassa, Dominic, Simmons, Aaron D., Lopes, Erika Barboza Prado, Kinter, Michael, Griffin, Timothy M.

Source: Journal of bone and mineral research. 37(12):2531-2547

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187913104.0x000001&indx=1&recIds=ETOCvdc_100187913104.0x000001

Obesity promotes lipid accumulation in mouse cartilage—A potential role of acetyl‐CoA carboxylase (ACC) mediated chondrocyte de novo lipogenesis

Authors: Liu, Huanhuan, Witzigreuter, Luke, Sathiaseelan, Roshini, Agbaga, Martin‐Paul, Brush, Richard S., Stout, Michael B., Zhu, Shouan

Source: Journal of orthopaedic research. 40(12):2771-2779

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165162077.0x000001&indx=1&recIds=ETOCvdc_100165162077.0x000001

High-Resolution Dissection of Chemical Reprogramming from Mouse Embryonic Fibroblasts into Fibrocartilaginous Cells

Authors: Chen, Yishan, Wu, Bingbing, Lin, Junxin, Yu, Dongsheng, Du, Xiaotian, Sheng, Zixuan, Yu, Yeke, An, Chengrui, Zhang, Xiaoan, Li, Qikai, Zhu, Shouan, Sun, Heng, Zhang, Xianzhu, Zhang, Shufang, Zhou, Jing, Bunpetch, Varitsara, El-Hashash, Ahmed, Ji, Junfeng, Ouyang, Hongwei

Source: In Stem Cell Reports 10 March 2020 14(3):478-492

Sodium lactate promotes stemness of human mesenchymal stem cells through KDM6B mediated glycolytic metabolism

Authors: Sun, Heng, Zhang, Xiaolei, Dai, Jun, Pan, Zongyou, Wu, Yan, Yu, Dongsheng, Zhu, Shouan, Chen, Yishan, Qin, Tian, Ouyang, Hongwei

Source: Biochemical and biophysical research communications. 532(3):433-439

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121275131.0x000001&indx=1&recIds=ETOCvdc_100121275131.0x000001

3D-Printed Extracellular Matrix/Polyethylene Glycol Diacrylate Hydrogel Incorporating the Anti-inflammatory Phytomolecule Honokiol for Regeneration of Osteochondral Defects

Authors: Zhu, Shouan, Chen, Pengfei, Chen, Yang, Li, Muzhi, Chen, Can, Lu, Hongbin

Source: American journal of sports medicine. 48(11):2808-2818

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN624638539&indx=1&recIds=ETOCRN624638539

Ezh2 Ameliorates Osteoarthritis by Activating TNFSF13B

Authors: Du, Xiaotian, Chen, Yishan, Zhang, Qin, Lin, Junxin, Yu, Yeke, Pan, Zongyou, Sun, Heng, Yuan, Chunhui, Yu, Dongsheng, Wu, Haoyu, Zhang, Xiaoan, Dai, Jun, Zhu, Shouan, Zhou, Yiting, Ouyang, Hongwei

Source: Journal of bone and mineral research. 35(5):956-965

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107143081.0x000001&indx=1&recIds=ETOCvdc_100107143081.0x000001

Glutathione as a mediator of cartilage oxidative stress resistance and resilience during aging and osteoarthritis

Authors: Zhu, Shouan, Makosa, Dawid, Miller, Benjamin, Griffin, Timothy M.

Source: Connective tissue research. 61(1):34-47

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100093496839.0x000001&indx=1&recIds=ETOCvdc_100093496839.0x000001

Growth hormone-receptor disruption in mice reduces osteoarthritis and chondrocyte hypertrophy.

Authors: Liu, Huanhuan, Davis, Trent, Duran-Ortiz, Silvana, Martino, Tom, Erdely, Austin, Profio, Shane, Osipov, Benjamin, Loots, Gabriela G., Berryman, Darlene E., O'Connor, Patrick M., Kopchick, John J., Zhu, Shouan

Source: GeroScience; Oct2024, Vol. 46 Issue 5, p4895-4908, 14p

Subject Terms: SOMATOTROPIN receptors, KNEE joint, BONE density, JOINTS (Anatomy), X-ray computed microtomography

Prostaglandin E2 mediates sensory nerve regulation of bone homeostasis

Authors: Chen, Hao, Hu, Bo, Lv, Xiao, Zhu, Shouan, Zhen, Gehua, Wan, Mei, Jain, Amit, Gao, Bo, Chai, Yu, Yang, Mi, Wang, Xiao, Deng, Ruoxian, Wang, Lei, Cao, Yong, Ni, Shuangfei, Liu, Shen, Yuan, Wen, Chen, Huajiang, Dong, Xinzhong, Guan, Yun, Yang, Huilin, Cao, Xu

Source: Nature communications. 10(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103858703.0x000001&indx=1&recIds=ETOCvdc_100103858703.0x000001

Silk fibroin-chondroitin sulfate scaffold with immuno-inhibition property for articular cartilage repair

Authors: Zhou, Feifei, Zhang, Xianzhu, Cai, Dandan, Li, Jun, Mu, Qin, Zhang, Wei, Zhu, Shouan, Jiang, Yangzi, Shen, Weiliang, Zhang, Shufang, Ouyang, Hong Wei

Source: In Acta Biomaterialia November 2017 63:64-75

Biomimetic tendon extracellular matrix composite gradient scaffold enhances ligament-to-bone junction reconstruction

Authors: Liu, Huanhuan, Yang, Long, Zhang, Erchen, Zhang, Rui, Cai, Dandan, Zhu, Shouan, Ran, Jisheng, Bunpetch, Varitsara, Cai, Youzhi, Heng, Boon Chin, Hu, Yejun, Dai, Xuesong, Chen, Xiao, Ouyang, Hongwei

Source: In Acta Biomaterialia 1 July 2017 56:129-140

The effects of lactate and acid on articular chondrocytes function: Implications for polymeric cartilage scaffold design

Authors: Zhang, Xiaolei, Wu, Yan, Pan, Zongyou, Sun, Heng, Wang, Junjuan, Yu, Dongsheng, Zhu, Shouan, Dai, Jun, Chen, Yishan, Tian, Naifeng, Heng, Boon Chin, Coen, Noelle D., Xu, Huazi, Ouyang, Hongwei

Source: In Acta Biomaterialia 15 September 2016 42:329-340

How are cell and tissue structure and function influenced by gravity and what are the gravity perception mechanisms?

Authors: Davis, Trent¹, Tabury, Kevin², Zhu, Shouan¹, Angeloni, Debora³, Baatout, Sarah², Benchoua, Alexandra⁴, Bereiter-Hahn, Juergen⁵, Bottai, Daniele⁶, Buchheim, Judith-Irina⁷, Calvaruso, Marco⁸, Carnero-Diaz, Eugénie⁹, Castiglioni, Sara¹⁰, Cavalieri, Duccio¹¹, Ceccarelli, Gabriele¹², Choukér, Alexander⁷, Cialdai, Francesca¹³, Ciofani, Gianni¹⁴, Coppola, Giuseppe¹⁵, Cusella, Gabriella¹², Degl'Innocenti, Andrea¹⁶

Source: NPJ Microgravity; 2/10/2024, Vol. 10 Issue 1, p1-7, 7p

Radially oriented collagen scaffold with SDF-1 promotes osteochondral repair by facilitating cell homing

Authors: Chen, Pengfei, Tao, Jiadong, Zhu, Shouan, Cai, Youzhi, Mao, Qijiang, Yu, Dongsheng, Dai, Jun, Ouyang, HongWei

Source: In Biomaterials January 2015 39:114-123

The amelioration of cartilage degeneration by ADAMTS-5 inhibitor delivered in a hyaluronic acid hydrogel

Authors: Chen, Pengfei, Zhu, Shouan, Wang, Yanyan, Mu, Qin, Wu, Yan, Xia, Qingqing, Zhang, Xiaolei, Sun, Heng, Tao, Jiadong, Hu, Hu, Lu, Ping, Ouyang, Hongwei

Source: In Biomaterials March 2014 35(9):2827-2836

604 - SIRT5 REGULATES CHOONDROCYTE METABOLIC DYSFUNCTIONS AND OSTEOARTHRITIS DEVELOPMENT DURING AGING AND OBESITY

Authors: Liu, Huanhuan, Zhu, Shouan

Source: In Osteoarthritis and Cartilage April 2024 32 Supplement 1:S424-S425

603 - GROWTH HORMONE PROMOTES JOINT DEGENERATION AND CHONDROCYTE METABOLIC DYSFUNCTION IN MICE

Authors: Zhu, Shouan, Liu, Huanhuan, Kopchick, John J.

Source: In Osteoarthritis and Cartilage April 2024 32 Supplement 1:S423-S424

GC-MS Metabolic Profiling of Mouse Hip Articular Cartilage: In vivo versus In vitro Comparisons
Orthopaedic Research Society

Authors: Batushansky, Albert, Lopes, Erika Barboza Prado, Zhu, Shouan, Humphries, Kenneth M., Griffin, Timothy M.

Source: Transactions of the annual meeting. 65:442-442

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Effect of Increased Dietary Fat and Sirtuin 3 Deficiency on PRG^+Chondrocyte Progenitor Cells
Orthopaedic Research Society

Authors: Zhu, Shouan, Makosa, Dawid, Barboza, Erika, Batushansky, Albert, Griffin, Timothy M.

Source: Transactions of the annual meeting. 65:370-370

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCCN605533277&indx=1&recIds=ETOCCN605533277