Systems serology-based comparison of antibody effector functions induced by adjuvanted vaccines to guide vaccine design.

Authors: Loos, Carolin, Coccia, Margherita, Didierlaurent, Arnaud M., Essaghir, Ahmed, Fallon, Jonathan K., Lauffenburger, Douglas, Luedemann, Corinne, Michell, Ashlin, van der Most, Robbert, Zhu, Alex Lee, Alter, Galit, Burny, Wivine

Source: NPJ Vaccines; 3/8/2023, Vol. 8 Issue 1, p1-15, 15p

Subject Terms: IMMUNE response, IMMUNOGLOBULINS, FC receptors, IMMUNOLOGIC memory, IMMUNOLOGICAL adjuvants, B cells, ANTIBODY titer, VACCINES

A Single Human VH-gene Allows for a Broad-Spectrum Antibody Response Targeting Bacterial Lipopolysaccharides in the Blood

Authors: Sangesland, Maya, Yousif, Ashraf S., Ronsard, Larance, Kazer, Samuel W., Zhu, Alex Lee, Gatter, G. James, Hayward, Matthew R., Barnes, Ralston M., Quirindongo-Crespo, Maricel, Rohrer, Daniel, Lonberg, Nils, Kwon, Douglas, Shalek, Alex K., Lingwood, Daniel

Source: In Cell Reports 25 August 2020 32(8)

Protective antibodies elicited by SARS-CoV-2 spike protein vaccination are boosted in the lung after challenge in nonhuman primates.

Authors: Francica, Joseph R., Flynn, Barbara J., Foulds, Kathryn E., Noe, Amy T., Werner, Anne P., Moore, Ian N., Gagne, Matthew, Johnston, Timothy S., Tucker, Courtney, Davis, Rachel L., Flach, Britta, O'Connell, Sarah, Andrew, Shayne F., Lamb, Evan, Flebbe, Dillon R., Nurmukhambetova, Saule T., Donaldson, Mitzi M., Todd, John-Paul M., Zhu, Alex Lee, Atyeo, Caroline

Source: Science Translational Medicine; 8/18/2021, Vol. 13 Issue 607, p1-17, 17p

Subject Terms: IMMUNOGLOBULINS, SARS-CoV-2, CONVALESCENT plasma, VIRUS diseases, IMMUNOGLOBULIN G, ANTIBODY formation

Discrete SARS-CoV-2 antibody titers track with functional humoral stability.

Authors: Bartsch, Yannic C., Fischinger, Stephanie, Siddiqui, Sameed M., Chen, Zhilin, Yu, Jingyou, Gebre, Makda, Atyeo, Caroline, Gorman, Matthew J., Zhu, Alex Lee, Kang, Jaewon, Burke, John S., Slein, Matthew, Gluck, Matthew J., Beger, Samuel, Hu, Yiyuan, Rhee, Justin, Petersen, Eric, Mormann, Benjamin, Aubin, Michael de St, Hasdianda, Mohammad A.

Source: Nature Communications; 2/15/2021, Vol. 12 Issue 1, p1-8, 8p

Subject Terms: ANTIBODY titer, SARS-CoV-2, VACCINE approval, T cells, ANTIBODY formation, NEUTRALIZATION tests, MYOCARDIAL reperfusion

V Gene Diversity Allows the B Cell Receptor to Accommodate Specific Antigen Shapes

Authors: Zhu, Alex Lee

Contributors: Lingwood, Daniel, Pillai, Shiv, Carroll, Michael C.

File Description: application/pdf

Access URL: http://nrs.harvard.edu/urn-3:HUL.InstRepos:39010112

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