The Novel Ribonucleotide Reductase Inhibitor COH29 Inhibits DNA Repair In Vitro

Authors: Chen, Mei-Chuan, Zhou, Bingsen, Zhang, Keqiang, Yuan, Yate-Ching, Un, Frank, Hu, Shuya, Chou, Chih-Ming, Chen, Chun-Han, Wu, Jun, Wang, Yan, Liu, Xiyong, Smith, D. Lynne, Li, Hongzhi, Liu, Zheng, Warden, Charles D., Su, Leila, Malkas, Linda H., Chung, Young Min, Hu, Mickey C.-T., Yen, Yun ^{*, 1}

Source: In Molecular Pharmacology June 2015 87(6):996-1005

Preclinical study of the cyclodextrin-polymer conjugate of camptothecin CRLX101 for the treatment of gastric cancer

Authors: Gaur, Shikha, Chen, Linling, Yen, Terence, Wang, Yafan, Zhou, Bingsen, Davis, Mark, Yen, Yun

Source: In Nanomedicine: Nanotechnology, Biology, and Medicine July 2012 8(5):721-730

Systemic delivery of siRNA nanoparticles targeting RRM2 suppresses head and neck tumor growth

Authors: Rahman, Mohammad Aminur, Amin, A.R.M. Ruhul, Wang, Xu, Zuckerman, Jonathan E., Choi, Chung Hang J., Zhou, Bingsen, Wang, Dongsheng, Nannapaneni, Sreenivas, Koenig, Lydia, Chen, Zhengjia, Chen, Zhuo (Georgia), Yen, Yun, Davis, Mark E., Shin, Dong M.

Source: In Journal of Controlled Release 10 May 2012 159(3):384-392

ATM-Mediated Serine 72 Phosphorylation Stabilizes Ribonucleotide Reductase Small Subunit p53R2 Protein against MDM2 to DNA Damage

Authors: Chang, Lufen, Zhou, Bingsen, Hu, Shuya, Guo, Robin, Liu, Xiyong, Jones, Stephen N., Yen, Yun

Source: Proceedings of the National Academy of Sciences of the United States of America, 2008 Nov . 105(47), 18519-18524.

Access URL: https://www.jstor.org/stable/25465493

Synthesis and biological activity of novel N6-substituted and 2, N6-disubstituted adenine ribo- and 3′- C-methyl-ribonucleosides as antitumor agents

Authors: Cappellacci, Loredana, Petrelli, Riccardo, Franchetti, Palmarisa, Vita, Patrizia, Kusumanchi, Praveen, Kumar, Mohineesh, Jayaram, Hiremagalur N., Zhou, Bingsen, Yen, Yun, Grifantini, Mario

Source: In European Journal of Medicinal Chemistry 2011 46(5):1499-1504

Reciprocal regulation of autophagy and dNTP pools in human cancer cells

Authors: Chen, Wei, Zhang, Lisheng, Zhang, Keqiang, Zhou, Bingsen, Kuo, Mei-Ling, Hu, Shuya, Chen, Linling, Tang, Michelle, Chen, Yun-Ru, Yang, Lixin, Ann, David K, Yen, Yun

Source: Autophagy. 10(7):1272-1284

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100056849751.0x000001&indx=1&recIds=ETOCvdc_100056849751.0x000001

Inhibitory mechanisms of heterocyclic carboxaldehyde thiosemicabazones for two forms of human ribonucleotide reductase

Authors: Zhu, Lijun, Zhou, Bingsen, Chen, Xinhuan, Jiang, Hongjuan, Shao, Jimin, Yen, Yun

Source: In Biochemical Pharmacology 2009 78(9):1178-1185

Ribonucleotide Reductase Subunits M2 and p53R2 are Potential Biomarkers for Metastasis of Colon Cancer

Authors: Liu, Xiyong, Zhou, Bingsen, Xue, Lijun, Yen, Frank, Chu, Peiguo, Un, Frank, Yen, Yun

Source: In Clinical Colorectal Cancer 2007 6(5):374-381

An increase of cytochrome C oxidase mediated disruption of gemcitabine incorporation into DNA in a resistant KB clone

Authors: Liu, Xiyong, Zhou, Bingsen, Mi, Shu, Xue, Lijun, Shih, Jennifer, Lee, Janice, Chau, Jennifer, Un, Frank, Yen, Yun

Source: In Biochemical Pharmacology 2007 73(12):1927-1938

The Induction of Growth Arrest DNA Damage-Inducible Gene 45 β in Human Hepatoma Cell Lines by S-Adenosylmethionine

Authors: Qiu, Weihua, Zhou, Bingsen, Chu, Peiguo G., Luh, Frank, Yen, Yun

Source: In The American Journal of Pathology 2007 171(1):287-296

Enzymatic property analysis of p53R2 subunit of human ribonucleotide reductase

Authors: Yen, Yun, Chu, Bernard, Yen, Christina, Shih, Jennifer, Zhou, Bingsen

Source: In Advances in Enzyme Regulation 2006 46(1):235-247

Characterization of enzymatic properties of human ribonucleotide reductase holoenzyme reconstituted in vitro from hRRM1, hRRM2, and p53R2 subunits

Authors: Qiu, Weihua, Zhou, Bingsen, Darwish, Dana, Shao, Jimin, Yen, Yun

Source: In Biochemical and Biophysical Research Communications 2006 340(2):428-434

2.6 AÅ; X-ray Crystal Structure of Human p53R2, a p53-Inducible Ribonucleotide Reductase.

Authors: Smith, Peter, Zhou, Bingsen, Ho, Nam

Source: Biochemistry; November 24 2009, Vol. 48 Issue 46, p11134-11141, 8p

The ribonucleotide reductase subunit M2B subcellular localization and functional importance for DNA replication in physiological growth of KB cells

Authors: Liu, Xiyong, Zhou, Bingsen, Xue, Lijun, Shih, Jennifer, Tye, Karen, Qi, Christina, Yen, Yun ^*

Source: In Biochemical Pharmacology 2005 70(9):1288-1297

Determination of the potency and subunit-selectivity of ribonucleotide reductase inhibitors with a recombinant-holoenzyme-based in vitro assay

Authors: Shao, Jimin, Zhou, Bingsen, Zhu, Lijun, Bilio, Angel J. Di, Su, Leila, Yuan, Yate-Ching, Ren, Shijun, Lien, Eric J., Shih, Jennifer, Yen, Yun ^*

Source: In Biochemical Pharmacology 2005 69(4):627-634

Nuclear factor Y regulation and promoter transactivation of human ribonucleotide reductase subunit M2 gene in a Gemcitabine resistant KB clone

Authors: Liu, Xiyong, Zhou, Bingsen, Xue, Lijun, Qiu, Weihua, Shih, Jennifer, Zheng, Shu, Yen, Yun

Source: In Biochemical Pharmacology 2004 67(8):1499-1511

Hypermethylation of Growth Arrest DNA Damage-Inducible Gene 45 β Promoter in Human Hepatocellular Carcinoma

Authors: Qiu, Weihua, Zhou, Bingsen, Zou, Hongzhi, Liu, Xiyong, Chu, Peiguo G., Lopez, Richard, Shih, Jennifer, Chung, Christopher, Yen, Yun

Source: In The American Journal of Pathology 2004 165(5):1689-1699

Down-Regulation of Growth Arrest DNA Damage-Inducible Gene 45β Expression Is Associated with Human Hepatocellular Carcinoma

Authors: Qiu, Weihua, David, Donald, Zhou, Bingsen, Chu, Peiguo G., Zhang, Bohe, Wu, Mengchao, Xiao, Jiacheng, Han, Tianquan, Zhu, Zhenggang, Wang, Tianxiang, Liu, Xiyong, Lopez, Richard, Frankel, Paul, Jong, Ambrose, Yen, Yun

Source: In The American Journal of Pathology 2003 162(6):1961-1974

Overexpression of RRM2 decreases thrombspondin-1 and increases VEGF production in human cancer cells in vitro and in vivo: implication of RRM2 in angiogenesis

Authors: Zhou Bingsen, Liu Xiyong, Wang Xiaochen, Lu Jianming, Chen Linling, Wu Jun, Hu Shuya, Zhang Keqiang, Yen Yun

Source: Molecular Cancer, Vol 8, Iss 1, p 11 (2009)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.molecular-cancer.com/content/8/1/11; https://doaj.org/toc/1476-4598

Access URL: https://doaj.org/article/6b9cc97506cc426d9dc3a9334002fa88

Inhibitory activity of medicinal mushroom Ganoderma lucidumon colorectal cancer by attenuating inflammation

Authors: Liu, Mandy M, Liu, Tiantian, Yeung, Steven, Wang, Zhijun, Andresen, Bradley, Parsa, Cyrus, Orlando, Robert, Zhou, Bingsen, Wu, Wei, Li, Xia, Zhang, Yilong, Wang, Charles, Huang, Ying

Source: Precision Clinical Medicine; December 2021, Vol. 4 Issue: 4 p231-245, 15p