Marrow adipogenic lineage precursors (MALPs) facilitate bone marrow recovery after chemotherapy

Authors: Wang, Huan ^{a, 1}, Yao, Lutian ^{a, b, 1}, Zhong, Leilei ^{a, 1}, Fang, Jiankang ^{a, 1}, He, Qi ^a, Busch, Theresa M. ^c, Cengel, Keith ^c, Qin, Ling ^{a, ⁎}

Source: In Bone June 2025 195

Activating EGFR Signaling Attenuates Osteoarthritis Development Following Loading Injury in Mice

Authors: Gui, Tao, Wei, Yulong, Luo, Lijun, Li, Jun, Zhong, Leilei, Yao, Lutian, Beier, Frank, Nelson, Charles L., Tsourkas, Andrew, Liu, X. Sherry, Enomoto‐Iwamoto, Motomi, Yu, Feifan, Cheng, Zhiliang, Qin, Ling

Source: Journal of bone and mineral research. 37(12):2498-2511

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187912982.0x000001&indx=1&recIds=ETOCvdc_100187912982.0x000001

EGFR Signaling Is Required for Maintaining Adult Cartilage Homeostasis and Attenuating Osteoarthritis Progression

Authors: Wei, Yulong, Ma, Xiaoyuan, Sun, Hao, Gui, Tao, Li, Jun, Yao, Lutian, Zhong, Leilei, Yu, Wei, Han, Biao, Nelson, Charles L., Han, Lin, Beier, Frank, Enomoto‐Iwamoto, Motomi, Ahn, Jaimo, Qin, Ling

Source: Journal of bone and mineral research. 37(5):1012-1023

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100150050129.0x000001&indx=1&recIds=ETOCvdc_100150050129.0x000001

Superoxide dismutase-loaded porous polymersomes as highly efficient antioxidant nanoparticles targeting synovium for osteoarthritis therapy

Authors: Gui, Tao, Luo, Lijun, Chhay, Bonirath, Zhong, Leilei, Wei, Yulong, Yao, Lutian, Yu, Wei, Li, Jun, Nelson, Charles L., Tsourkas, Andrew, Qin, Ling, Cheng, Zhiliang

Source: In Biomaterials April 2022 283

Marrow adipogenic lineage precursor: A new cellular component of marrow adipose tissue

Authors: Zhong, Leilei, Yao, Lutian, Seale, Patrick, Qin, Ling

Source: In Best Practice & Research Clinical Endocrinology & Metabolism July 2021 35(4)

Gli1 Defines a Subset of Fibro‐adipogenic Progenitors that Promote Skeletal Muscle Regeneration With Less Fat Accumulation

Authors: Yao, Lutian, Tichy, Elisia D, Zhong, Leilei, Mohanty, Sarthak, Wang, Luqiang, Ai, Emily, Yang, Shuying, Mourkioti, Foteini, Qin, Ling

Source: Journal of bone and mineral research. 36(6):1159-1173

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138595060.0x000001&indx=1&recIds=ETOCvdc_100138595060.0x000001

A Novel Enzymatic Digestion Approach for Isolation and Culture of Rodent Bone Marrow Mesenchymal Progenitors

Authors: Zhong, Leilei, Yao, Lutian, Qin, Ling

Source: Methods in molecular biology. 2221:29-40

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN624882670&indx=1&recIds=ETOCRN624882670

ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in health and disease

Authors: Schivo, Stefano, Khurana, Sakshi, Govindaraj, Kannan, Scholma, Jetse, Kerkhofs, Johan, Zhong, Leilei, Huang, Xiaobin, van de Pol, Jaco, Langerak, Rom, van Wijnen, André J., Geris, Liesbet, Karperien, Marcel, Post, Janine N.

Source: In Cellular Signalling April 2020 68

Different response of human chondrocytes from healthy looking areas and damaged regions to IL1β stimulation under different oxygen tension

Authors: Huang, Xiaobin, Zhong, Leilei, Hendriks, Jan, Post, Janine N., Karperien, Marcel

Source: Journal of orthopaedic research. 37(1):84-93

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100093667983.0x000001&indx=1&recIds=ETOCvdc_100093667983.0x000001

Periarticular Mesenchymal Progenitors Initiate and Contribute to Secondary Ossification Center Formation During Mouse Long Bone Development

Authors: Tong, Wei, Tower, Robert J., Chen, Chider, Wang, Luqiang, Zhong, Leilei, Wei, Yulong, Sun, Hao, Cao, Gaoyuan, Jia, Haoruo, Pacifici, Maurizio, Koyama, Eiki, Enomoto‐Iwamoto, Motomi, Qin, Ling

Source: Stem cells. 37(5):677-689

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100090576506.0x000001&indx=1&recIds=ETOCvdc_100090576506.0x000001

Promoted Chondrogenesis of Cocultured Chondrocytes and Mesenchymal Stem Cells under Hypoxia Using In-situ Forming Degradable Hydrogel Scaffolds

Authors: Huang, Xiaobin, Hou, Yong, Zhong, LeiLei, Huang, Dechun, Qian, Hongliang, Karperien, Marcel, Chen, Wei

Source: Biomacromolecules. 19(1):94-102

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632283902&indx=1&recIds=ETOCRN632283902

Proteasome inhibitor bortezomib is a novel therapeutic agent for focal radiation‐induced osteoporosis

Authors: Chandra, Abhishek, Wang, Luqiang, Young, Tiffany, Zhong, Leilei, Tseng, Wei‐Ju, Levine, Michael A., Cengel, Keith, Liu, X. Sherry, Zhang, Yejia, Pignolo, Robert J., Qin, Ling

Source: FASEB journal. 32(1):52-62

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103330066.0x000001&indx=1&recIds=ETOCvdc_100103330066.0x000001

Co-treatment of TGF-β3 and BMP7 is superior in stimulating chondrocyte redifferentiation in both hypoxia and normoxia compared to single treatments

Authors: Huang, Xiaobin, Zhong, Leilei, Post, Janine, Karperien, Marcel

Source: Scientific reports. 8(1):1-10

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171401644.0x000001&indx=1&recIds=ETOCvdc_100171401644.0x000001

Single cell RNA sequencing reveals emergent notochord‐derived cell subpopulations in the postnatal nucleus pulposus.

Authors: Zhang, Chenghao¹ (AUTHOR), Zhong, Leilei¹ (AUTHOR), Lau, Yian Khai¹ (AUTHOR), Wu, Meilun¹ (AUTHOR), Yao, Lutian¹ (AUTHOR), Schaer, Thomas P.² (AUTHOR), Mauck, Robert L.^1,3 (AUTHOR), Malhotra, Neil R.^1,4 (AUTHOR), Qin, Ling¹ (AUTHOR), Smith, Lachlan J.^1,3,4 (AUTHOR) lachlans@pennmedicine.upenn.edu

Source: FASEB Journal. Jan2024, Vol. 38 Issue 1, p1-15. 15p.

T Cell Factor 4 Is a Pro-catabolic and Apoptotic Factor in Human Articular Chondrocytes by Potentiating Nuclear Factor κB Signaling

Authors: Ma, Bin, Zhong, Leilei, van Blitterswijk, Clemens A., Post, Janine N., Karperien, Marcel

Source: In Journal of Biological Chemistry 14 June 2013 288(24):17552-17558

Study on Regional Strata Movement during Deep Mining of Erdos Coal Field and Its Control.

Authors: Zhang, Guojian, Wang, Zhiyang, Guo, Guangli, Wei, Wei, Wang, Fugang, Zhong, Leilei, Gong, Yaqiang

Source: International Journal of Environmental Research & Public Health; Nov2022, Vol. 19 Issue 22, p14902, 32p

The Effects of the WNT-Signaling Modulators BIO and PKF118-310 on the Chondrogenic Differentiation of Human Mesenchymal Stem Cells.

Authors: Huang, Xiaobin¹ x.huang-1@utwente.nl, Zhong, Leilei¹, Hendriks, Jan¹, Post, Janine N.¹, Karperien, Marcel¹ h.b.j.karperien@utwente.nl

Source: International Journal of Molecular Sciences. Feb2018, Vol. 19 Issue 2, p561. 15p.

Subject Terms: *MESENCHYMAL stem cells, *MULTIPOTENT stem cells, *BONE marrow transplantation, *CELL proliferation, *CHONDROGENESIS, *HUMAN growth hormone, *PHYSIOLOGY

Deciphering The In Vivo Heterogeneity Of Mouse Bone Marrow Mesenchymal Progenitors At Single Cell Resolution
Orthopaedic Research Society

Authors: Zhong, Leilei, Tower, Robert, Park, Jihwan, Wang, Luqiang, Shrestha, Rojesh, Seale, Patrick, Susztak, Kaitlin, Qin, Ling

Source: Transactions of the annual meeting. 65:137-137

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The Expressions of Dickkopf-Related Protein 1 and Frizzled-Related Protein Are Negatively Correlated to Local Inflammation and Osteoarthritis Severity.

Authors: Huang, Xiaobin, Zhong, Leilei, van Helvoort, Eefje, Lafeber, Floris, Mastbergen, Simon, Hendriks, Jan, Post, Janine N., Karperien, Marcel

Source: Cartilage; Oct2021, Vol. 12 Issue 4, p496-504, 9p

Targeting cartilage EGFR pathway for osteoarthritis treatment.

Authors: Wei, Yulong, Luo, Lijun, Gui, Tao, Yu, Feifan, Yan, Lesan, Yao, Lutian, Zhong, Leilei, Yu, Wei, Han, Biao, Patel, Jay M., Liu, Jessica F., Beier, Frank, Levin, Lawrence Scott, Nelson, Charles, Shao, Zengwu, Han, Lin, Mauck, Robert L., Tsourkas, Andrew, Ahn, Jaimo, Cheng, Zhiliang

Source: Science Translational Medicine; 1/13/2021, Vol. 13 Issue 576, p1-14, 14p

Subject Terms: EPIDERMAL growth factor receptors, ARTICULAR cartilage, CARTILAGE, OSTEOARTHRITIS, INTRA-articular injections, CHARCOT joints