Armored bicistronic CAR T cells with dominant-negative TGF-β receptor II to overcome resistance in glioblastoma

Authors: Li, Nannan, Rodriguez, Jesse L., Yin, Yibo, Logun, Meghan T., Zhang, Logan, Yu, Shengkun, Hicks, Kelly A., Zhang, Jiasi Vicky, Zhang, Laura, Xie, Chuncheng, Wang, Jiabin, Wang, Tianyu, Xu, Jiayi, Fraietta, Joseph A., Binder, Zev A., Lin, Zhiguo, O’Rourke, Donald M.

Source: In Molecular Therapy 2 October 2024 32(10):3522-3538

The IAP antagonist birinapant enhances chimeric antigen receptor T cell therapy for glioblastoma by overcoming antigen heterogeneity

Authors: Song, Edward Z., Wang, Xin, Philipson, Benjamin I., Zhang, Qian, Thokala, Radhika, Zhang, Logan, Assenmacher, Charles-Antoine, Binder, Zev A., Ming, Guo-li, O’Rourke, Donald M., Song, Hongjun, Milone, Michael C.

Source: In Molecular Therapy - Oncolytics 15 December 2022 27:288-304

Locally secreted BiTEs complement CAR T cells by enhancing killing of antigen heterogeneous solid tumors

Authors: Yin, Yibo, Rodriguez, Jesse L., Li, Nannan, Thokala, Radhika, Nasrallah, MacLean P., Hu, Li, Zhang, Logan, Zhang, Jiasi Vicky, Logun, Meghan T., Kainth, Devneet, Haddad, Leila, Zhao, Yang, Wu, Tong, Johns, Emily X., Long, Yu, Liang, Hongsheng, Qi, Jiping, Zhang, Xiangtong, Binder, Zev A., Lin, Zhiguo, O'Rourke, Donald M.

Source: Molecular therapy. 30(7):2537-2553

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167134815.0x000001&indx=1&recIds=ETOCvdc_100167134815.0x000001

Examination of optimized protocols for pCASL: Sensitivity to macrovascular contamination, flow dispersion, and prolonged arterial transit time

Authors: Zhang, Logan X., Woods, Joseph G., Okell, Thomas W., Chappell, Michael A.

Source: Magnetic resonance in medicine. 86(4):2208-2219

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132314457.0x000001&indx=1&recIds=ETOCvdc_100132314457.0x000001

Reproducibility of arterial spin labeling cerebral blood flow image processing: A report of the ISMRM open science initiative for perfusion imaging (OSIPI) and the ASL MRI challenge.

Authors: Paschoal, Andre M., Woods, Joseph G., Pinto, Joana, Bron, Esther E., Petr, Jan, Kennedy McConnell, Flora A., Bell, Laura, Dounavi, Maria‐Eleni, van Praag, Cassandra Gould, Mutsaerts, Henk J. M. M., Taylor, Aaron Oliver, Zhao, Moss Y., Brumer, Irène, Chan, Wei Siang Marcus, Toner, Jack, Hu, Jian, Zhang, Logan X., Domingos, Catarina, Monteiro, Sara P., Figueiredo, Patrícia

Source: Magnetic Resonance in Medicine; Aug2024, Vol. 92 Issue 2, p836-852, 17p

Subject Terms: CEREBRAL circulation, PERFUSION imaging, SPIN labels, IMAGE processing, OPEN scholarship

Checkpoint Blockade Reverses Anergy in IL-13Rα2 Humanized scFv-Based CAR T Cells to Treat Murine and Canine Gliomas

Authors: Yin, Yibo, Boesteanu, Alina C., Binder, Zev A., Xu, Chong, Reid, Reiss A., Rodriguez, Jesse L., Cook, Danielle R., Thokala, Radhika, Blouch, Kristin, McGettigan-Croce, Bevin, Zhang, Logan, Konradt, Christoph, Cogdill, Alexandria P., Panjwani, M. Kazim, Jiang, Shuguang, Migliorini, Denis, Dahmane, Nadia, Posey, Avery D., Jr., June, Carl H., Mason, Nicola J., Lin, Zhiguo, O’Rourke, Donald M., Johnson, Laura A.

Source: In Molecular Therapy - Oncolytics 21 December 2018 11:20-38

Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development

Authors: Binder, Zev A., Thorne, Amy Haseley, Bakas, Spyridon, Wileyto, E. Paul, Bilello, Michel, Akbari, Hamed, Rathore, Saima, Ha, Sung Min, Zhang, Logan, Ferguson, Cole J., Dahiya, Sonika, Bi, Wenya Linda, Reardon, David A., Idbaih, Ahmed, Felsberg, Joerg, Hentschel, Bettina, Weller, Michael, Bagley, Stephen J., Morrissette, Jennifer J.D., Nasrallah, MacLean P., Ma, Jianhui, Zanca, Ciro, Scott, Andrew M., Orellana, Laura, Davatzikos, Christos, Furnari, Frank B., O'Rourke, Donald M.

Source: In Cancer Cell 9 July 2018 34(1):163-177

Transcriptome signatures associated with meningioma progression

Authors: Viaene, Angela, Zhang, Bo, Martinez-Lage, Maria, Xiang, Chaomei, Tosi, Umberto, Thawani, Jayesh, Gungor, Busra, Zhu, Yuankun, Roccograndi, Laura, Zhang, Logan, Bailey, Robert, Storm, Phillip, O'Rourke, Donald, Resnick, Adam, Grady, M., Dahmane, Nadia

Source: Acta neuropathologica communications. 7(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187395985.0x000001&indx=1&recIds=ETOCvdc_100187395985.0x000001

High-Affinity Chimeric Antigen Receptor With Cross-Reactive scFv to Clinically Relevant EGFR Oncogenic Isoforms.

Authors: Thokala, Radhika, Binder, Zev A., Yin, Yibo, Zhang, Logan, Zhang, Jiasi Vicky, Zhang, Daniel Y., Milone, Michael C., Ming, Guo-li, Song, Hongjun, O'Rourke, Donald M.

Source: Frontiers in Oncology; 9/10/2021, Vol. 11, p1-11, 11p

Subject Terms: CHIMERIC antigen receptors, EPIDERMAL growth factor receptors, T cells, DISEASE relapse

IMMU-48. RATIONAL DEVELOPMENT AND CHARACTERIZATION OF MULTIVALENT TARGETING TANDEM AND PARALLEL CAR T CELLS FOR GLIOMA

Authors: Yin, Yibo, Thokala, Radhika, Zhang, Logan, Kainth, Devneet, Haddad, Leila, Binder, Zev, Lin, Zhiguo, O'Rourke, Donald

Source: Neuro-oncology. 21(Supplement 6):vi129-vi129

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100097091976.0x000001&indx=1&recIds=ETOCvdc_100097091976.0x000001

CSIG-25. EPIDERMAL GROWTH FACTOR RECEPTOR EXTRACELLULAR DOMAIN MISSENSE MUTATION A289V AS A DRIVER OF GLIOBLASTOMA INVASION AND PROLIFERATION

Authors: Binder, Zev, Thorne, Amy, Bakas, Spyridon, Wileyto, E Paul, Akbari, Hamed, Rathore, Saima, Min Ha, Sung, Zhang, Logan, Idbaih, Ahmed, Bagley, Stephen, Morrissette, Jennifer, Nasrallah, MacLean, Ma, Jianhui, Zanca, Ciro, Scott, Andrew, Davatzikos, Christos, Furnari, Frank, O'Rourke, Donald

Source: Neuro-oncology. 20(suppl 6):vi48-vi48

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100094743143.0x000001&indx=1&recIds=ETOCvdc_100094743143.0x000001

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