A multicenter, randomized, double‐blind, placebo‐controlled, crossover trial to evaluate the efficacy and safety of zolmitriptan nasal spray for the acute treatment of migraine in patients aged 6 to 11 years, with an open‐label extension

Authors: Yonker, Marcy E., McVige, Jennifer, Zeitlin, Leonid, Visser, Hester

Source: Headache. 62(9):1207-1217

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185480852.0x000001&indx=1&recIds=ETOCvdc_100185480852.0x000001

Duration of benefit per Dose: Carbidopa-Levodopa immediate release vs. extended release capsules (Rytary®)

Authors: Hauser, Robert A., Zeitlin, Leonid, Fisher, Stanley, D'Souza, Richard

Source: In Parkinsonism and Related Disorders January 2021 82:133-137

Nephrocalcinosis tendency does not worsen under burosumab treatment for X-linked hypophosphatemic rickets: a multicenter pediatric study.

Authors: Levi, Shelly, Landau, Daniel, Davidovits, Miriam, Shapira Rootman, Mika, Brener, Avivit, Gal, Shoshana, Borovitz, Yael, Goldberg, Ori, Bello, Rachel, Cleper, Roxana, Lebenthal, Yael, Levy-Shraga, Yael, Tiosano, Dov, Chezana, Adi, Regev, Ravit, Zeitlin, Leonid

Source: Frontiers in Pediatrics; 2024, p1-8, 8p

The effect of growth hormone treatment in a child with tricho-rhino-phalangeal syndrome: A case report and review of the literature

Authors: Levy-Shraga, Yael, Modan-Moses, Dalit, Wientroub, Shlomo, Ovadia, Dror, Zeitlin, Leonid

Source: In European Journal of Medical Genetics April 2020 63(4)

Heterozygous mutations in the straitjacket region of the latency-associated peptide domain of TGFB2 cause Camurati–Engelmann disease type II

Authors: Wang, Zheng, Kometani, Mitsuhiro, Zeitlin, Leonid, Wilnai, Yael, Kinoshita, Akira, Yoshiura, Koh-ichiro, Ninomiya, Hiroko, Imamura, Takeshi, Guo, Long, Xue, Jingyi, Yan, Li, Ohashi, Hirofumi, Pretemer, Yann, Kawai, Shunsuke, Shiina, Masaaki, Ogata, Kazuhiro, Cohn, Daniel H., Matsumoto, Naomichi, Nishimura, Gen, Toguchida, Junya, Miyake, Noriko, Ikegawa, Shiro

Source: Journal of Human Genetics; November 2024, Vol. 69 Issue: 11 p599-605, 7p

Long-term use of interleukin-1 inhibitors reduce flare activity in patients with fibrodysplasia ossificans progressiva.

Authors: Haviv, Ruby^1,2 ruby.haviv@clalit.org.il, Zeitlin, Leonid^2,3, Moshe, Veronica¹, Ziv, Amit^1,2, Rabinowicz, Noa¹, Benedetti, Fabrizio De⁴, Prencipe, Giusi⁴, Matteo, Valentina⁴, Cunto, Carmen Laura De⁵, Hsiao, Edward C⁶, Uziel, Yosef^1,2

Source: Rheumatology. Sep2024, Vol. 63 Issue 9, p2597-2604. 8p.

Subject Terms: *FIBRODYSPLASIA ossificans progressiva, *DISEASE exacerbation, *RESEARCH funding, *HEALTH status indicators, *VISUAL analog scale, *QUESTIONNAIRES, *TREATMENT duration, *TREATMENT effectiveness, *BLOOD plasma, *PAIN, *RESEARCH, *CASE studies, *DISEASE relapse, *HEALTH outcome assessment, *INTERLEUKIN-1, *GLUCOCORTICOIDS, *INTERLEUKINS, *WELL-being, *CHEMICAL inhibitors

RPL13 Variants Cause Spondyloepimetaphyseal Dysplasia with Severe Short Stature

Authors: Le Caignec, Cedric, Ory, Benjamin, Lamoureux, François, O'Donohue, Marie-Francoise, Orgebin, Emilien, Lindenbaum, Pierre, Téletchéa, Stéphane, Saby, Manon, Hurst, Anna, Nelson, Katherine, Gilbert, Shawn R., Wilnai, Yael, Zeitlin, Leonid, Segev, Eitan, Tesfaye, Robel, Nizon, Mathilde, Cogne, Benjamin, Bezieau, Stéphane, Geoffroy, Loic, Hamel, Antoine, Mayrargue, Emmanuelle, de Courtivron, Benoît, Decock-Giraudaud, Aliette, Charrier, Céline, Pichon, Olivier, Retière, Christelle, Redon, Richard, Pepler, Alexander, McWalter, Kirsty, Da Costa, Lydie, Toutain, Annick, Gleizes, Pierre-Emmanuel, Baud'huin, Marc, Isidor, Bertrand

Source: American journal of human genetics. 105(5):1040-1047

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100092595554.0x000001&indx=1&recIds=ETOCvdc_100092595554.0x000001

Cardiovascular health in pediatric patients with X-linked hypophosphatemia under two years of burosumab therapy.

Authors: Brener, Avivit, Cleper, Roxana, Baruch, Guy, Rothschild, Ehud, Yackobovitch-Gavan, Michal, Beer, Gil, Zeitlin, Leonid, Kapusta, Livia

Source: Frontiers in Endocrinology; 2024, p1-8, 8p

Subject Terms: CHILD patients, HYPOPHOSPHATEMIA, FIBROBLAST growth factors, CARDIOVASCULAR diseases risk factors, MANUFACTURING defects, BLOOD pressure

Acute and chronic rapamycin use in patients with Fibrodysplasia Ossificans Progressiva: A report of two cases

Authors: Kaplan, Frederick S., Zeitlin, Leonid, Dunn, Stephen P., Benor, Shira, Hagin, David, Al Mukaddam, Mona, Pignolo, Robert J.

Source: Bone. 109:281-284

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100065663734.0x000001&indx=1&recIds=ETOCvdc_100065663734.0x000001

Safety and Efficacy of IPX203 in Parkinson's Disease: The RISE‐PD Open‐Label Extension Study.

Authors: Espay, Alberto J., Hauser, Robert A., Dhall, Rohit, Thakkar, Sandeep, Cloud, Leslie, Zeitlin, Leonid, Banisadr, Ghazal, Fisher, Stanley, Visser, Hester

Source: Movement Disorders; Feb2024, Vol. 39 Issue 2, p428-432, 5p

Massive Cervical Heterotopic Ossification and Extra-Articular Temporomandibular Joint Ankylosis

Authors: Haviv, Ruby, Zeitlin, Leonid, Hashkes, Philip J., Uziel, Yosef

Source: Journal of pediatrics. 248:127-128

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100172791620.0x000001&indx=1&recIds=ETOCvdc_100172791620.0x000001

Linear growth of children with X-linked hypophosphatemia treated with burosumab: a real-life observational study.

Authors: Levy-Shraga, Yael, Levi, Shelly, Regev, Ravit, Gal, Shoshana, Brener, Avivit, Lebenthal, Yael, Gillis, David, Strich, David, Zung, Amnon, Cleper, Roxana, Borovitz, Yael, Bello, Rachel, Tenenbaum, Ariel, Zadik, Zvi, Davidovits, Miriam, Zeitlin, Leonid, Tiosano, Dov

Source: European Journal of Pediatrics; Nov2023, Vol. 182 Issue 11, p5191-5202, 12p

Subject Terms: GROWTH of children, HYPOPHOSPHATEMIA, SOMATOTROPIN, CHILD patients, SCIENTIFIC observation

XLH Matters 2022: Insights and recommendations to improve outcomes for people living with X-linked hypophosphataemia (XLH).

Authors: Seefried, Lothar, Alzahrani, Ali, Arango Sancho, Pedro, Bacchetta, Justine, Crowley, Rachel, Emma, Francesco, Gibbins, Jonathan, Grandone, Anna, Javaid, Muhammad Kassim, Mindler, Gabriel, Raimann, Adalbert, Rothenbuhler, Anya, Tucker, Ian, Zeitlin, Leonid, Linglart, Agnès

Source: Orphanet Journal of Rare Diseases; 10/27/2023, Vol. 18 Issue 2, p1-16, 16p

Subject Terms: FRACTURE healing, TRANSITIONAL care, PHYSICAL mobility, YOUNG adults, TEENAGE pregnancy

IPX203 vs Immediate-Release Carbidopa-Levodopa for the Treatment of Motor Fluctuations in Parkinson Disease: The RISE-PD Randomized Clinical Trial.

Authors: Hauser, Robert A., Espay, Alberto J., Ellenbogen, Aaron L., Fernandez, Hubert H., Isaacson, Stuart H., LeWitt, Peter A., Ondo, William G., Pahwa, Rajesh, Schwarz, Johannes, Stocchi, Fabrizio, Zeitlin, Leonid, Banisadr, Ghazal, Fisher, Stanley, Visser, Hester, D'Souza, Richard

Source: JAMA Neurology; Oct2023, Vol. 80 Issue 10, p1062-1069, 8p

Identification of Disease Gene for Camurati-Engelmann Disease, Type II

Authors: Wang, Zheng, Xue, Jingyi, Nishimura, Gen, Kometani, Mitsuhiro, Wilnai, Yael, Zeitlin, Leonid, Kinoshita, Akira, Yoshiura, Koh-ichiro, Imamura, Takeshi, Ohashi, Hirofumi, Kawai, Shunsuke, Shiina, Masaaki, Ogata, Kazuhiro, Miyake, Noriko, Toguchida, Junya, Superti-Furga, Andrea, Matsumoto, Naomichi, Ikegawa, Shiro

Source: In Bone Reports May 2022 16 Supplement

The effect of cyclical intravenous pamidronate in children and adolescents with osteogenesis imperfecta Type V

Authors: Zeitlin, Leonid, Rauch, Frank, Travers, Rose, Munns, Craig, Glorieux, Francis H.

Source: In Bone 2006 38(1):13-20

Cementless posterior spinal fusion for the treatment of OI patients with severe spine deformity—a case series.

Authors: Gurel, Ron, Ovadia, Dror, Lebel, David E., Zeitlin, Leonid, Sigal, Amit

Source: European Spine Journal; Jun2022, Vol. 31 Issue 6, p1566-1572, 7p, 2 Black and White Photographs, 1 Chart

Subject Terms: SPINE abnormalities, SPINAL fusion, SURGICAL site infections, OSTEOGENESIS imperfecta, REOPERATION, SPINAL surgery

Looking for the skeleton in the closet—rare genetic diagnoses in patients with diabetes and skeletal manifestations.

Authors: Brener, Avivit^1,2 (AUTHOR) avivitb@tlvmc.gov.il, Zeitlin, Leonid^2,3 (AUTHOR), Wilnai, Yael^2,4 (AUTHOR), Birk, Ohad S.⁵ (AUTHOR), Rosenfeld, Talya^1,6 (AUTHOR), Chorna, Efrat^1,7 (AUTHOR), Lebenthal, Yael^1,2 (AUTHOR)

Source: Acta Diabetologica. May2022, Vol. 59 Issue 5, p711-719. 9p.

Subject Terms: *GENETIC disorder diagnosis, *DIAGNOSIS of diabetes, *TRANSFER RNA, *LIPODYSTROPHY, *PEOPLE with diabetes, *PANCREATIC beta cells

Body composition and cardiometabolic health of pediatric patients with X-linked hypophosphatemia (XLH) under burosumab therapy.

Authors: Brener, Avivit, Lebenthal, Yael, Cleper, Roxana, Kapusta, Livia, Zeitlin, Leonid

Source: Therapeutic Advances in Endocrinology & Metabolism; 3/16/2021, p1-10, 10p

Carbidopa and Levodopa Extended Release Capsules in Patients with and without Troublesome and Non-Troublesome Dyskinesia.

Authors: Hauser, Robert A.¹ (AUTHOR) rhauser@usf.edu, Zeitlin, Leonid² (AUTHOR), Fisher, Stanley³ (AUTHOR), D'Souza, Richard³ (AUTHOR)

Source: Journal of Parkinson's Disease. 2020, Vol. 10 Issue 3, p915-925. 11p.

Subject Terms: *DYSKINESIAS, *DOPA, *CARBIDOPA, *PHARMACOKINETICS