SGLT2-Inhibition in Patients With Alport Syndrome

Authors: Boeckhaus, Jan, Gale, Daniel P., Simon, James, Ding, Jie, Zhang, Yanqin, Bergmann, Carsten, Turner, A. Neil, Hall, Matthew, Sayer, John A., Srivastava, Shalabh, Kang, Hee Gyung, Cerkauskaite-Kerpauskiene, Agne, Gillion, Valentine, Claes, Kathleen J., Krueger, Bastian, de Fallois, Jonathan, Walden, Ulrike, Choi, Mira, Schueler, Markus, Mueller, Roman-Ulrich, Todorova, Polina, Hohenstein, Bernd, Zeisberg, Michael, Friede, Tim, Knebelmann, Bertrand, Halbritter, Jan, Gross, Oliver

Source: In Kidney International Reports December 2024 9(12):3490-3500

Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells

Authors: Mahadevan, Krishnan K., LeBleu, Valerie S., Ramirez, Elena V., Chen, Yang, Li, Bingrui, Sockwell, Amari M., Gagea, Mihai, Sugimoto, Hikaru, Sthanam, Lakshmi Kavitha, Tampe, Desiree, Zeisberg, Michael, Ying, Haoqiang, Jain, Abhinav K., DePinho, Ronald A., Maitra, Anirban, McAndrews, Kathleen M., Kalluri, Raghu

Source: In Developmental Cell 11 September 2023 58(17):1562-1577

Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer

Authors: Chen, Yang, Yang, Sujuan, Tavormina, Jena, Tampe, Desiree, Zeisberg, Michael, Wang, Huamin, Mahadevan, Krishnan K., Wu, Chang-Jiun, Sugimoto, Hikaru, Chang, Chia-Chi, Jenq, Robert R., McAndrews, Kathleen M., Kalluri, Raghu

Source: In Cancer Cell 8 August 2022 40(8):818-834

Urinary Dickkopf-3 as a Potential Marker for Estimated Glomerular Filtration Rate Decline in Patients With Heart Failure.

Authors: Pieper, Dennis, Sandek, Anja, Schäfer, Ann-Kathrin, Dihazi, Hassan, Dihazi, Gry Helene, Leha, Andreas, Zeisberg, Michael, Lüders, Stephan, Koziolek, Michael, Wallbach, Manuel

Source: Journal of the American Heart Association; 12/3/2024, Vol. 13 Issue 23, p1-13, 13p

Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer

Authors: Becker, Lisa M., O’Connell, Joyce T., Vo, Annie P., Cain, Margo P., Tampe, Desiree, Bizarro, Lauren, Sugimoto, Hikaru, McGow, Anna K., Asara, John M., Lovisa, Sara, McAndrews, Kathleen M., Zielinski, Rafal, Lorenzi, Philip L., Zeisberg, Michael, Raza, Sughra, LeBleu, Valerie S., Kalluri, Raghu

Source: In Cell Reports 2 June 2020 31(9)

Loss of tet methyl cytosine dioxygenase 3 (TET3) enhances cardiac fibrosis via modulating the DNA damage repair response.

Authors: Rath, Sandip Kumar, Nyamsuren, Gunsmaa, Tampe, Björn, Yu, David Sung-wen, Hulshoff, Melanie S., Schlösser, Denise, Maamari, Sabine, Zeisberg, Michael, Zeisberg, Elisabeth M.

Source: Clinical Epigenetics; 8/27/2024, Vol. 16 Issue 1, p1-20, 20p

Subject Terms: HOMOLOGOUS recombination, DOUBLE-strand DNA breaks, HEART fibrosis, DEOXYRIBOZYMES, DNA damage, DNA repair

Causal Connections From Chronic Kidney Disease to Cardiac Fibrosis

Authors: Hulshoff, Melanie S. ^*, Rath, Sandip K. ^*, Xu, Xingbo ^*, Zeisberg, Michael, Zeisberg, Elisabeth M. ^*

Source: In Seminars in Nephrology November 2018 38(6):629-636

Chromatin dynamics at the core of kidney fibrosis

Authors: Tampe, Björn, Zeisberg, Michael

Source: In Matrix Biology August 2018 68-69:194-229

Interdisziplinäre Fallkonferenzen als Chance für Myositis-Patienten?

Authors: Korsten, Peter, Rademacher, Jan-Gerd, Seitz, Cornelia, Zschüntzsch, Jana, Mößner, Rotraut, Zeisberg, Michael, Olgemöller, Ulrike, Buck, Cordula, Zechel, Sabrina, Müller, Gerhard, Vasko, Radovan, Schmidt, Jens

Source: Nervenheilkunde. 38(6):377-380

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186588439.0x000001&indx=1&recIds=ETOCvdc_100186588439.0x000001

Human Tumstatin and Human Endostatin Exhibit Distinct Antiangiogenic Activities Mediated by αvβ3 and α5β1 Integrins

Authors: Sudhakar, Akulapalli, Sugimoto, Hikaru, Yang, Changqing, Lively, Julie, Zeisberg, Michael, Kalluri, Raghu

Source: Proceedings of the National Academy of Sciences of the United States of America, 2003 Apr . 100(8), 4766-4771.

Access URL: https://www.jstor.org/stable/3144016

Low-dose hydralazine prevents fibrosis in a murine model of acute kidney injury–to–chronic kidney disease progression

Authors: Tampe, Björn, Steinle, Ulrike, Tampe, Désirée, Carstens, Julienne L., Korsten, Peter, Zeisberg, Elisabeth M., Müller, Gerhard A., Kalluri, Raghu, Zeisberg, Michael

Source: In Kidney International January 2017 91(1):157-176

17 - Tubulointerstitielle Nierenerkrankungen

Authors: Zeisberg, Michael

Source: In Klinikleitfaden Nephrologie Edition: Second Edition. 2024:369-382

3D virtual histology of murine kidneys –high resolution visualization of pathological alterations by micro computed tomography

Authors: Missbach-Guentner, Jeannine, Pinkert-Leetsch, Diana, Dullin, Christian, Ufartes, Roser, Hornung, Daniel, Tampe, Bjoern, Zeisberg, Michael, Alves, Frauke

Source: Scientific reports. 8(1):1-14

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111629658.0x000001&indx=1&recIds=ETOCvdc_100111629658.0x000001

High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis

Authors: Xu, Xingbo, Tan, Xiaoying, Tampe, Björn, Wilhelmi, Tim, Hulshoff, Melanie, Saito, Shoji, Moser, Tobias, Kalluri, Raghu, Hasenfuss, Gerd, Zeisberg, Elisabeth, Zeisberg, Michael

Source: Nature communications. 9(1):1-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178402883.0x000001&indx=1&recIds=ETOCvdc_100178402883.0x000001

Partial Epithelial-to-Mesenchymal Transition and Other New Mechanisms of Kidney Fibrosis

Authors: Lovisa, Sara, Zeisberg, Michael, Kalluri, Raghu

Source: In Trends in Endocrinology & Metabolism October 2016 27(10):681-695

Differentiation of functional endothelial cells from human induced pluripotent stem cells: A novel, highly efficient and cost effective method

Authors: Liu, Xiaopeng, Qi, Jing, Xu, Xingbo, Zeisberg, Michael, Guan, Kaomei, Zeisberg, Elisabeth M.

Source: In Differentiation October-November 2016 92(4):225-236

Single-nucleus transcriptomics reveals adrenergic and STAT3 signalling in paradoxical low-flow low-gradient-specific cardiomyocyte subclusters: implications for aortic stenosis pathogenesis and treatment.

Authors: Xu, Xingbo, Tan, Xiaoying, Cui, Baolong, Paul, Niels B, Elkenani, Manar, Beuthner, Bo E, Li, Weichao, Mohamed, Belal A, Schnelle, Moritz, Puls, Miriam, Zeisberg, Elisabeth M, Zeisberg, Michael, Beißbarth, Tim, Toischer, Karl, Hasenfuß, Gerd

Source: Cardiovascular Research; Sep2024, Vol. 120 Issue 13, p1505-1507, 3p

Subject Terms: HEART valve prosthesis implantation, AORTIC stenosis, CARDIAC hypertrophy, GENE expression, MYOCARDIUM, CARDIAC contraction

Snail Is a Direct Target of Hypoxia-inducible Factor 1α (HIF1α) in Hypoxia-induced Endothelial to Mesenchymal Transition of Human Coronary Endothelial Cells

Authors: Xu, Xingbo, Tan, Xiaoying, Tampe, Björn, Sanchez, Elisa, Zeisberg, Michael, Zeisberg, Elisabeth M.

Source: In Journal of Biological Chemistry 3 July 2015 290(27):16653-16664

Induction of Tet3-dependent Epigenetic Remodeling by Low-dose Hydralazine Attenuates Progression of Chronic Kidney Disease

Authors: Tampe, Björn, Tampe, Desiree, Zeisberg, Elisabeth M., Müller, Gerhard A., Bechtel-Walz, Wibke, Koziolek, Michael, Kalluri, Raghu, Zeisberg, Michael

Source: In EBioMedicine January 2015 2(1):19-36

Thrombospondin-1 Deficiency Causes a Shift from Fibroproliferative to Inflammatory Kidney Disease and Delays Onset of Renal Failure

Authors: Zeisberg, Michael, Tampe, Björn, LeBleu, Valerie, Tampe, Desiree, Zeisberg, Elisabeth M., Kalluri, Raghu

Source: In The American Journal of Pathology October 2014 184(10):2687-2698