Differences in immunogenicity of TP53-mutated cancers with low tumor mutational burden (TMB) A study on TP53mut endometrial-, ovarian- and triple-negative breast cancer

Authors: Steger, Katharina ^a, Fiegl, Heidelinde ^a, Feroz, Barin ^a, Leitner, Katharina ^a, Marth, Christian ^a, Hackl, Hubert ^{b, ⁎, 1}, Zeimet, Alain G. ^{a, ⁎⁎, 1}

Source: In European Journal of Cancer 26 March 2025 219

Validation and clinical performance of a single test, DNA based endometrial cancer molecular classifier

Authors: Jamieson, Amy ^{1, 2}, Grube, Marcel ³, Kommoss, Felix ⁴, Lum, Amy ⁵, Leung, Samuel ⁵, Chiu, Derek ⁵, Henderson, Gabriel ⁶, Heitz, Florian ⁷, Heublein, Sabine ⁴, Zeimet, A G ⁸, Hasenburg, Annette ⁹, Diebold, Joachim ¹⁰, Walter, Christina ³, Staebler, Annette ¹¹, Reynolds, Jerian ¹², Lapuk, Anna ¹², McConechy, Melissa K ¹², Huntsman, David G ^{2, 13}, Gilks, Blake ¹⁴, Kommoss, Stefan ³, McAlpine, Jessica N ^{1, 2, *}

Source: In International Journal of Gynecological Cancer December 2024 34(12):1888-1897

Pegylated liposomal doxorubicin combined with trabectedin as a treatment option in uterine sarcomas: a single-institution retrospective analysis

Authors: Steinlechner, Magdalena, Strobel, Laura, Leitner, Katharina, Pan, Teresa L., Feroz, Barin, Marth, Christian, Zeimet, Alain G. ^*

Source: In International Journal of Gynecological Cancer August 2024 34(8):1196-1202

Verification of the prognostic precision of the new 2023 FIGO staging system in endometrial cancer patients – An international pooled analysis of three ESGO accredited centres

Authors: Schwameis, Richard, Fanfani, Francesco, Ebner, Christoph, Zimmermann, Naomi, Peters, Inge, Nero, Camilla, Marth, Christian, Ristl, Robin, Leitner, Katharina, Grimm, Christoph, Oberndorfer, Felicitas, Capasso, Ilaria, Zeimet, Alain G., Polterauer, Stephan, Scambia, Giovanni, Fagotti, Anna, Concin, Nicole

Source: In European Journal of Cancer November 2023 193

Treatment strategies in patients with gynecological sarcoma: Results of the prospective intergroup real-world registry for gynecological sarcoma in Germany (REGSA-NOGGO RU1)

Authors: Roser, Eva ¹, Harter, Philipp ², Zocholl, Dario ³, Denschlag, Dominik ⁴, Chekerov, Radoslav ¹, Wimberger, Pauline ⁵, Kurzeder, Christian ⁶, Hasenburg, Annette ⁷, Muallem, Mustafa-Zelal ¹, Mustea, Alexander ⁸, Emons, Guenter ⁹, Zeimet, A G ¹⁰, Beck, Felix ¹, Arndt, Tjadina ¹, Brucker, Sara Y ¹¹, Kommoss, Stefan ¹¹, Heitz, Florian ², Welz, Julia ², Egger, Eva-Katharina ⁸, Kalder, Matthias ¹², Buderath, Paul ¹³, Klar, Maximilian ¹⁴, Marth, Christian ¹⁰, Ulrich, Uwe Andreas ¹⁵, Weigel, Michael ¹⁶, Traub, Lea ¹⁷, Anthuber, Christoph ¹⁸, Strauss, Hans ¹⁹, Hanker, Lars ²⁰, Link, Theresa ⁵, Kubiak, Karol ²¹, Melekian, Badrig ²², Hornung, Daniela ²³, Pölcher, Martin ²⁴, Lampe, Bjoern ²⁵, Krauß, Thomas ²⁶, Keilholz, Ulrich ²⁷, Flörcken, Anne ²⁸, Pietzner, Klaus ¹, Sehouli, Jalid ^{1, 27, *}

Source: In International Journal of Gynecological Cancer February 2023 33(2):223-230

Dubious effects of methadone as an “anticancer” drug on ovarian cancer cell-lines and patient-derived tumor-spheroids

Authors: Fiegl, Heidelinde, Hagenbuchner, Judith, Kyvelidou, Christiana, Seeber, Beata, Sopper, Sieghart, Tsibulak, Irina, Wieser, Verena, Reiser, Elisabeth, Roessler, Julia, Huhtinen, Kaisa, Carpén, Olli, Parson, Walther, Sprung, Susanne, Marth, Christian, Ausserlechner, Michael J., Zeimet, Alain G.

Source: In Gynecologic Oncology April 2022 165(1):129-136

Bevacizumab and platinum-based combinations for recurrent ovarian cancer: a randomised, open-label, phase 3 trial

Authors: Ackermann, Sven, Anthuber, Christoph, Aydogdu, Mustafa, Baldauf, Angelika, Bauer, Wolfgang, Behringer, Dirk, Belau, Antje, Bender, Alexandra, Brucker, Cosima, Burges, Alexander, Canzler, Ulrich, Daabach, Trygve, Denschlag, Dominik, Deryal, Mustafa, Dörfel, Steffen, Ebert, Juliane, El-Balat, Ahmed, Fehm, Tanja, Feidicker, Susanne Maria, Feisel-Schwickardi, Gabriele, Felberbaum, Ricardo, Frank, Matthias, Gebauer, Gerhard, Gerber, Bernd, Gerhardt, Axel, Grafe, Andrea, Griesshammer, Martin, Grischke, Eva-Maria, Gröll, Isolde, Gropp-Meier, Martina, Hager, Dietrich, Hanf, Volker, Hannig, Carla Verena, Hantschmann, Peer, Harter, Philipp, Hauzenberger, Tanja, Herwig, Uwe, Heubner, Martin, Hielscher, Carsten, Hilpert, Felix, Hitschold, Thomas, Hofmann, Manfred, Jackisch, Christian, Janni, Wolfgang, Kiesel, Ludwig, Ko, Yon-Dschun, Koch, Hans-Joachim, Krabisch, Petra, Krieger, Peter, Kubin, Thomas, Kühn, Thorsten, Lampe, Björn, Ledwon, Peter, Lemster, Sabine, Lex, Benno, Liebrich, Clemens, Lorenz, Ralf, Lück, Hans-Joachim, Mahner, Sven, Mallmann, Peter, Marmé, Frederik, Meier, Werner, Meinerz, Wolfgang, Menke, Götz, Möbus, Volker, Müller, Thomas, Müller, Volker, Neunhöffer, Tanja, Ober, Angelika, Oskay-Özcelik, Gülten, Ostertag, Horst, Park-Simon, Tjoung-Won, Pölcher, Martin, Rautenberg, Beate, Rein, Daniel, Reiter, Wilhelm, Rempen, Andreas, Runnebaum, Ingo, Schmalfeldt, Barbara, Schmidt, Marcus, Schnohr, Sabine, Scholz, Heinz, Schröder, Willibald, Sehouli, Jalid, Simon, Eike, Sperfeld, Antje, Steckkönig, Annette, Strauß, Hans-Georg, Stuth, Ronaldo, Terhaag, Jürgen, Thiel, Falk, Thill, Marc, Tomé, Oliver, Uleer, Christoph, Vogel, Susanne, Voß, Hermann, Weigel, Michael, Winkler, Ulrich, Wischnik, Arthur, Zeiser, Tobias, Zorr, Andreas, Glasspool, Ros, Hudson, Emma, Jones, Rachel, Lafleur, Judith, Marth, Christian, Petru, Edgar, Reinthaller, Alexander, Antill, Yoland, Azer, Mary, Baron-Hay, Sally, Beale, Philip, Begbie, Stephen, Black, Allison, Briscoe, Karen, Dean, Andrew, Goh, Jeffrey, Harvey, Sandra, Lee, Chee, Matos, Marco, Meniawy, Tarek, Olesen, Inger, Shannon, Catherine, Vasey, Paul, Abadie-Lacourtoisie, Sophie, Arsene, Olivier, Barthier, Sophie, Becuwe-Roemer, Célia, Berton-Rigaud, Dominique, Cappiello-Bataller, Maria, Catala, Stéphanie, Costan, Cristina, Del Piano, Francesco, Deplanque, Gaël, Despax, Raymond, Dohollou, Nadine, Garnier-Tixidré, Claire, Grenier, Julien, Guardiola, Emmanuel, Hardy-Bessard, Anne-Claire, Joly, Florence, Kurtz, Jean-Emmanuel, Lefeuvre-Plesse, Claudia, Leheurteur, Marianne, Lesoin, Anne, Levache, Charles-Briac, L'Haridon, Tifenn, Longo, Raffaele, Lortholary, Alain, Meunier, Jérôme, Mouret-Reynier, Marie-Ange, Petit, Thierry, Raban, Nadia, Romano, Olivier, Vannetzel, Jean-Michel, Zannetti, Alain, Pfisterer, Jacobus ^*, Shannon, Catherine M, Baumann, Klaus, Rau, Joern, Dean, Andrew P, Hein, Alexander, Zeimet, Alain G, Hanker, Lars C, Glasspool, Rosalind, de Gregorio, Nikolaus, Meniawy, Tarek M, Goh, Jeffrey C, Baron Hay, Sally, Kommoss, Stefan, du Bois, Andreas

Source: In The Lancet Oncology May 2020 21(5):699-709

Hopes and failures in front-line ovarian cancer therapy

Authors: Tsibulak, Irina, Zeimet, Alain G., Marth, Christian

Source: In Critical Reviews in Oncology / Hematology November 2019 143:14-19

Sacituzumab Govitecan In Platinum-Resistant Epithelial Ovarian Cancer In A Real-Life Clinical Setting

Authors: Prast, Isabel, Marth, Christian, Zeimet, Alain G., Tsibulak, Irina

Source: In International Journal of Gynecological Cancer February 2025 35(2) Supplement 1

Homologous Recombination Deficiency (HRD) In P53 Abnormal Endometrial Carcinoma

Authors: Mittelstadt, Suzana ^{1, 2}, Staebler, Annette ³, Walter, Christina B. ², Denkert, Carsten ⁴, Romey, Marcel ⁴, Knoll, Katharina ⁵, Zeimet, Alain G. ⁵, Diebold, Joachim ⁶, Heitz, Florian ⁷, Kommoss, Stefan ^{1, 2}, Grube, Marcel Philip ^{1, 2}

Source: In International Journal of Gynecological Cancer February 2025 35(2) Supplement 1

BRCA loss of function including BRCA1 DNA-methylation, but not BRCA-unrelated homologous recombination deficiency, is associated with platinum hypersensitivity in high-grade ovarian cancer.

Authors: Fiegl, Heidelinde, Schnaiter, Simon, Reimer, Daniel U., Leitner, Katharina, Nardelli, Petra, Tsibulak, Irina, Wieser, Verena, Wimmer, Katharina, Schamschula, Esther, Marth, Christian, Zeimet, Alain G.

Source: Clinical Epigenetics; 11/27/2024, Vol. 16 Issue 1, p1-10, 10p

Subject Terms: HOMOLOGOUS recombination, GENE expression, CANCER relapse, TREATMENT effectiveness, BRCA genes, POLY ADP ribose

The game-changing impact of POLE mutations in oncology--a review from a gynecologic oncology perspective.

Authors: Kög, Johanna, Pan, Teresa L., Marth, Christian, Zeimet, Alain G.

Source: Frontiers in Oncology; 2024, p1-11, 11p

Subject Terms: SOMATIC mutation, TREATMENT effectiveness, GYNECOLOGIC oncology, DNA polymerases, ENDOMETRIAL cancer

Heterogeneity of Cancer Stem Cells: Rationale for Targeting the Stem Cell Niche

Authors: Boesch, Maximilian, Sopper, Sieghart, Zeimet, Alain G., Reimer, Daniel, Gastl, Guenther, Ludewig, Burkhard, Wolf, Dominik

Source: In BBA - Reviews on Cancer December 2016 1866(2):276-289

Carboplatin and pegylated liposomal doxorubicin versus carboplatin and paclitaxel in very platinum-sensitive ovarian cancer patients: Results from a subset analysis of the CALYPSO phase III trial

Authors: Mahner, Sven, Meier, Werner, du Bois, Andreas, Brown, Chris, Lorusso, Domenica, Dell’Anna, Tiziana, Cretin, Jacques, Havsteen, Hanne, Bessette, Paul, Zeimet, Alain G., Vergote, Ignace, Vasey, Paul, Pujade-Lauraine, Eric, Gladieff, Laurence, Ferrero, Annamaria

Source: In European Journal of Cancer February 2015 51(3):352-358

miR-21-3p is a positive regulator of L1CAM in several human carcinomas

Authors: Doberstein, Kai, Bretz, Niko P., Schirmer, Uwe, Fiegl, Heidi, Blaheta, Roman, Breunig, Christian, Müller-Holzner, Elisabeth, Reimer, Dan, Zeimet, Alain G., Altevogt, Peter ^*

Source: In Cancer Letters 28 November 2014 354(2):455-466

Plasma concentrations of the vitamin E-binding protein afamin are associated with overall and progression-free survival and platinum sensitivity in serous ovarian cancer—a study by the OVCAD consortium

Authors: Melmer, Andreas, Fineder, Linda, Lamina, Claudia, Kollerits, Barbara, Dieplinger, Benjamin, Braicu, Ioana, Sehouli, Jalid, Cadron, Isabelle, Vergote, Ignace, Mahner, Sven, Zeimet, Alain G., Castillo-Tong, Dan Cacsire, Ebenbichler, Christoph F., Zeillinger, Robert, Dieplinger, Hans

Source: In Gynecologic Oncology January 2013 128(1):38-43

Neoadjuvant Chemotherapy Cannot Be Regarded as Adequate Routine Therapy Strategy of Advanced Ovarian Cancer

Authors: du Bois, Andreas ^{⁎, ⁎⁎}, Marth, Christian ^†, Pfisterer, Jacobus ^⁎, Harter, Philipp ^⁎, Hilpert, Felix ^⁎, Zeimet, Alain G. ^†, Sehouli, Jalid ^⁎

Source: In International Journal of Gynecological Cancer August 2011 21(6):1165-1168

DNA ploidy, nuclear size, proliferation index and DNA-hypomethylation in ovarian cancer

Authors: Zeimet, Alain G., Fiegl, Heidi, Goebel, Georg, Kopp, Francis, Allasia, Claude, Reimer, Daniel, Steppan, Ilona, Mueller-Holzner, Elisabeth, Ehrlich, Melanie, Marth, Christian

Source: In Gynecologic Oncology April 2011 121(1):24-31

High IL-12 p35 and IL-23 p19 mRNA expression is associated with superior outcome in ovarian cancer

Authors: Wolf, Anna Maria, Rumpold, Holger, Reimer, Daniel, Marth, Christian, Zeimet, Alain G., Wolf, Dominik

Source: In Gynecologic Oncology 2010 118(3):244-250

Validation of intraoperative risk assessment on frozen section for surgical management of endometrial carcinoma

Authors: Egle, Daniel, Grissemann, Barbara, Zeimet, Alain G., Müller-Holzner, Elisabeth, Marth, Christian

Source: In Gynecologic Oncology 2008 110(3):286-292