Cell type and regulatory analysis in amphioxus illuminates evolutionary origin of the vertebrate head

Authors: Anna Markos, Jan Kubovciak, Simona Mikula Mrstakova, Anna Zitova, Jan Paces, Simona Machacova, Zbynek Kozmik-Jr, Zbynek Kozmik, Iryna Kozmikova

Source: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

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Genetic analysis of medaka fish illuminates conserved and divergent roles of Pax6 in vertebrate eye development

Authors: Simona Mikula Mrstakova, Zbynek Kozmik

Source: Frontiers in Cell and Developmental Biology, Vol 12 (2024)

Subject Terms: lens, retina, eye evolution, vision, gene expression, Pax6, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2024.1448773/full; https://doaj.org/toc/2296-634X

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Ancestral role of Pax6 in chordate brain regionalization

Authors: Zbynek Kozmik, Iryna Kozmikova

Source: Frontiers in Cell and Developmental Biology, Vol 12 (2024)

Subject Terms: evolution, brain, eye, amphioxus, chordates, genome editing, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2024.1431337/full; https://doaj.org/toc/2296-634X

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Validated WGS and WES protocols proved saliva-derived gDNA as an equivalent to blood-derived gDNA for clinical and population genomic analyses

Authors: Katerina Kvapilova, Pavol Misenko, Jan Radvanszky, Ondrej Brzon, Jaroslav Budis, Juraj Gazdarica, Ondrej Pos, Marie Korabecna, Martin Kasny, Tomas Szemes, Petr Kvapil, Jan Paces, Zbynek Kozmik

Source: BMC Genomics, Vol 25, Iss 1, Pp 1-17 (2024)

Subject Terms: Genomics variant analysis, Saliva-derived gDNA, Whole genome sequencing, Whole exome sequencing, Validation guideline, Biotechnology, TP248.13-248.65, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2164

Access URL: https://doaj.org/article/a0a7b7e5449b4f6383ccc83c0d0fa3f4

Conserved enhancers control notochord expression of vertebrate Brachyury

Authors: Cassie L. Kemmler, Jana Smolikova, Hannah R. Moran, Brandon J. Mannion, Dunja Knapp, Fabian Lim, Anna Czarkwiani, Viviana Hermosilla Aguayo, Vincent Rapp, Olivia E. Fitch, Seraina Bötschi, Licia Selleri, Emma Farley, Ingo Braasch, Maximina Yun, Axel Visel, Marco Osterwalder, Christian Mosimann, Zbynek Kozmik, Alexa Burger

Source: Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/8918433ad9dc464ebd1fe886936070f5

Chromatin Remodeling Enzyme Snf2h Is Essential for Retinal Cell Proliferation and Photoreceptor Maintenance

Authors: Andrea Kuzelova, Naoko Dupacova, Barbora Antosova, Sweetu Susan Sunny, Zbynek Kozmik, Jan Paces, Arthur I. Skoultchi, Tomas Stopka

Source: Cells, Vol 12, Iss 7, p 1035 (2023)

Subject Terms: Snf2h, Smarca5, retina, photoreceptors, cell cycle, apoptosis, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/12/7/1035; https://doaj.org/toc/2073-4409

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mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia

Authors: Soyeon Lim, You-Joung Kim, Sooyeon Park, Ji-heon Choi, Young Hoon Sung, Katsuhiko Nishimori, Zbynek Kozmik, Han-Woong Lee, Jin Woo Kim

Source: eLife, Vol 10 (2021)

Subject Terms: retinal progenitor cell, mitotic division limit, clonal expansion, mTORC1, Hif1a, glycolysis, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/70079; https://doaj.org/toc/2050-084X

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A conserved regulatory program initiates lateral plate mesoderm emergence across chordates

Authors: Karin D. Prummel, Christopher Hess, Susan Nieuwenhuize, Hugo J. Parker, Katherine W. Rogers, Iryna Kozmikova, Claudia Racioppi, Eline C. Brombacher, Anna Czarkwiani, Dunja Knapp, Sibylle Burger, Elena Chiavacci, Gopi Shah, Alexa Burger, Jan Huisken, Maximina H. Yun, Lionel Christiaen, Zbynek Kozmik, Patrick Müller, Marianne Bronner, Robb Krumlauf, Christian Mosimann

Source: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/cfe6d2cea11f4fa1bf72c26475a34643

Optical Clearing and Light Sheet Microscopy Imaging of Amphioxus

Authors: Simona Machacova, Helena Chmelova, Anna Vavrova, Zbynek Kozmik, Iryna Kozmikova

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: amphioxus, light sheet microscopy, clearing technique, whole mount immunohistochemistry, photoreceptor, acetylated tubulin, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.702986/full; https://doaj.org/toc/2296-634X

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Wnt/β-Catenin Signaling Promotes Differentiation of Ischemia-Activated Adult Neural Stem/Progenitor Cells to Neuronal Precursors

Authors: Jan Kriska, Lucie Janeckova, Denisa Kirdajova, Pavel Honsa, Tomas Knotek, David Dzamba, Denisa Kolenicova, Olena Butenko, Martina Vojtechova, Martin Capek, Zbynek Kozmik, Makoto Mark Taketo, Vladimir Korinek, Miroslava Anderova

Source: Frontiers in Neuroscience, Vol 15 (2021)

Subject Terms: Wnt signaling, transgenic mouse, neural stem/progenitor cell, focal cerebral ischemia, adult neurogenesis, gliogenesis, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnins.2021.628983/full; https://doaj.org/toc/1662-453X

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Molecular Fingerprint of Amphioxus Frontal Eye Illuminates the Evolution of Homologous Cell Types in the Chordate Retina

Authors: Jiri Pergner, Anna Vavrova, Iryna Kozmikova, Zbynek Kozmik

Source: Frontiers in Cell and Developmental Biology, Vol 8 (2020)

Subject Terms: chordates, eye evolution, light detection, vision, gene expression, photoreceptors, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fcell.2020.00705/full; https://doaj.org/toc/2296-634X

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Neural crest cells require Meis2 for patterning the mandibular arch via the Sonic hedgehog pathway

Authors: Jaroslav Fabik, Katarina Kovacova, Zbynek Kozmik, Ondrej Machon

Source: Biology Open, Vol 9, Iss 6 (2020)

Subject Terms: meis, craniofacial, sonic hedgehog (shh) signalling, pharyngeal arch, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://bio.biologists.org/content/9/6/bio052043; https://doaj.org/toc/2046-6390

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Wnt/β-catenin signaling is an evolutionarily conserved determinant of chordate dorsal organizer

Authors: Iryna Kozmikova, Zbynek Kozmik

Source: eLife, Vol 9 (2020)

Subject Terms: body plan, axial patterning, evolution, wnt/β-catenin signaling, branchiostoma floridae, branchiostoma lanceolatum, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/56817; https://doaj.org/toc/2050-084X

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Tcf7L2 is essential for neurogenesis in the developing mouse neocortex

Authors: Olga Chodelkova, Jan Masek, Vladimir Korinek, Zbynek Kozmik, Ondrej Machon

Source: Neural Development, Vol 13, Iss 1, Pp 1-10 (2018)

Subject Terms: Neurogenenesis, Neocortex, Wnt signalling, Tcf7L1, Tcf7L2, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13064-018-0107-8; https://doaj.org/toc/1749-8104

Access URL: https://doaj.org/article/537928bfee7e4155ae9f6b3efb87bcb1

Dose-dependent regulation of horizontal cell fate by Onecut family of transcription factors.

Authors: Michaela Kreplova, Andrea Kuzelova, Barbora Antosova, Lucie Zilova, Herbert Jägle, Zbynek Kozmik

Source: PLoS ONE, Vol 15, Iss 8, p e0237403 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/348b2c4d8d7f497184157ae216d23575

The Gene Regulatory Network of Lens Induction Is Wired through Meis-Dependent Shadow Enhancers of Pax6.

Authors: Barbora Antosova, Jana Smolikova, Lucie Klimova, Jitka Lachova, Michaela Bendova, Iryna Kozmikova, Ondrej Machon, Zbynek Kozmik

Source: PLoS Genetics, Vol 12, Iss 12, p e1006441 (2016)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5137874?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/2b2bdba577094845b589e48271e267ab

Generation of mRx-Cre transgenic mouse line for efficient conditional gene deletion in early retinal progenitors.

Authors: Lucie Klimova, Jitka Lachova, Ondrej Machon, Radislav Sedlacek, Zbynek Kozmik

Source: PLoS ONE, Vol 8, Iss 5, p e63029 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3646923?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/dce8c5d8c3b349d59eb972e5df9136ab

Ectopic activation of Wnt/β-catenin signaling in lens fiber cells results in cataract formation and aberrant fiber cell differentiation.

Authors: Barbora Antosova, Jana Smolikova, Romana Borkovcova, Hynek Strnad, Jitka Lachova, Ondrej Machon, Zbynek Kozmik

Source: PLoS ONE, Vol 8, Iss 10, p e78279 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3813504?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/a1dbc38c169a4e1ea7f2df4eeaf0bd46

Conservation and diversification of an ancestral chordate gene regulatory network for dorsoventral patterning.

Authors: Iryna Kozmikova, Jana Smolikova, Cestmir Vlcek, Zbynek Kozmik

Source: PLoS ONE, Vol 6, Iss 2, p e14650 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0014650&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/4b4e31b21e244254981cbcf76748be88

A lens-specific co-injection marker for medaka transgenesis

Authors: Pavel Vopalensky, Jana Ruzickova, Barbora Pavlu, Zbynek Kozmik

Source: BioTechniques, Vol 48, Iss 3, Pp 235-236 (2010)

Subject Terms: transgenesis, co-injection marker, lens, fish, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/0736-6205; https://doaj.org/toc/1940-9818

Access URL: https://doaj.org/article/91920fbf4ba44792813f23de2ae8c356