Molecular genetic characterization of mixed-phenotype acute leukemia (MPAL) with BCR::ABL1 fusion

Authors: Shi, Sophia ^{a, b}, Zhou, Qianghua ^{a, b}, Zhao, Davidson ^{a, b}, Zarif, Mojgan ^a, Wei, Cuihong ^c, Sibai, Hassan ^d, Chang, Hong ^{a, b, ⁎}

Source: In Leukemia Research April 2025 151

A real-world analysis of clinical outcomes in AML with myelodysplasia-related changes: a comparison of ICC and WHO-HAEM5 criteria

Authors: Zhou, Qianghua, Zhao, Davidson, Zarif, Mojgan, Davidson, Marta B., Minden, Mark D., Tierens, Anne, Yeung, Yu Wing Tony, Wei, Cuihong, Chang, Hong

Source: In Blood Advances 9 April 2024 8(7):1760-1771

AML with CEBPA mutations: A comparison of ICC and WHO-HAEM5 criteria in patients with 20% or more blasts

Authors: Zhao, Davidson, Zhou, Qianghua, Zarif, Mojgan, Eladl, Entsar, Wei, Cuihong, Atenafu, Eshetu G., Schuh, Andre, Tierens, Anne, Yeung, Yu Wing Tony, Minden, Mark D., Chang, Hong

Source: In Leukemia Research November 2023 134

Impact of secondary‐type mutations in NPM1 mutated AML

Authors: Zhou, Qianghua, Zhao, Davidson, Zarif, Mojgan, Yeung, Yu Wing Tony, Richard‐Carpentier, Guillaume, Chang, Hong

Source: European journal of haematology. 111(1):165-168

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185754741.0x000001&indx=1&recIds=ETOCvdc_100185754741.0x000001

Molecular characterization of AML‐MRC reveals TP53 mutation as an adverse prognostic factor irrespective of MRC‐defining criteria, TP53 allelic state, or TP53 variant allele frequency

Authors: Zhao, Davidson, Eladl, Entsar, Zarif, Mojgan, Capo‐Chichi, José‐Mario, Schuh, Andre, Atenafu, Eshetu, Minden, Mark, Chang, Hong

Source: Cancer medicine. 12(6):6511-6522

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185281912.0x000001&indx=1&recIds=ETOCvdc_100185281912.0x000001

NPM1-mutated AML-MRC diagnosed on the basis of history of MDS or MDS/MPN frequently harbours secondary-type mutations and confers inferior outcome compared to AML with mutated NPM1

Authors: Zhao, Davidson, Zarif, Mojgan, Eladl, Entsar, Capo-Chichi, José-Mario, Smith, Adam C., Atenafu, Eshetu G., Tierens, Anne, Minden, Mark D., Schuh, Andre, Chang, Hong

Source: In Leukemia Research July 2022 118

TP53 Mutations in AML Patients Are Associated with Dismal Clinical Outcome Irrespective of Frontline Induction Regimen and Allogeneic Hematopoietic Cell Transplantation.

Authors: Zhao, Davidson^1,2 (AUTHOR), Zarif, Mojgan^1,2 (AUTHOR), Zhou, Qianghua^1,2 (AUTHOR), Capo-Chichi, José-Mario^1,2 (AUTHOR), Schuh, Andre³ (AUTHOR), Minden, Mark D.³ (AUTHOR), Atenafu, Eshetu G.⁴ (AUTHOR), Kumar, Rajat^3,5 (AUTHOR), Chang, Hong^1,2 (AUTHOR) hong.chang@uhn.ca

Source: Cancers. Jun2023, Vol. 15 Issue 12, p3210. 12p.

Subject Terms: *KRUSKAL-Wallis Test, *GENETIC mutation, *HOMOGRAFTS, *SEQUENCE analysis, *LOG-rank test, *RETROSPECTIVE studies, *ACQUISITION of data, *ALLELES, *REGRESSION analysis, *TREATMENT effectiveness, *CELLS, *MEDICAL records, *KAPLAN-Meier estimator, *DESCRIPTIVE statistics, *HEMATOPOIETIC stem cell transplantation, *DATA analysis software, *DISEASE remission, *OVERALL survival, *PROPORTIONAL hazards models

Impact of secondary‐type mutations in acute myeloid leukemia with CEBPA mutation.

Authors: Zhao, Davidson, Rumina, Musani, Zarif, Mojgan, Wei, Cuihong, Chang, Hong

Source: EJHaem; Dec2024, Vol. 5 Issue 6, p1370-1372, 3p

Oral pimonidazole unveils clinicopathologic and epigenetic features of hypoxic tumour aggressiveness in localized prostate cancer.

Authors: Ci, Xinpei, Chen, Sujun, Zhu, Rui, Zarif, Mojgan, Jain, Rahi, Guo, Wangyuan, Ramotar, Matthew, Gong, Linsey, Xu, Wenjie, Singh, Olivia, Mansouri, Sheila, Zadeh, Gelareh, Wei, Gong-Hong, Xu, Wei, Bristow, Robert, Berlin, Alejandro, Koritzinsky, Marianne, van der Kwast, Theodorus, He, Housheng Hansen

Source: BMC Cancer; 6/18/2024, Vol. 24 Issue 1, p1-12, 12p

Subject Terms: PROSTATE cancer, WHOLE genome sequencing, RADICAL prostatectomy, CLINICAL pathology, IMMUNOSTAINING, DNA methylation

T/myeloid MPAL with biallelic CEBPA mutations

Authors: Zarif, Mojgan, Chang, Hong

Source: In Blood 26 October 2023 142(17):1500-1500