Generation of a human iPSC line with heterozygous PRPF8 c.5792C > T, p. T1931M mutation to model retinitis pigmentosa using CRISPR/Cas9 technology

Authors: Hang Chen, Yuqin Liang, Yuexi Chen, Yuan Liang, Xiaoxue Li, Chunwen Duan, Zekai Cui, Jianing Gu, Chengcheng Ding, Xihao Sun, Jiansu Chen

Source: Stem Cell Research, Vol 84, Iss , Pp 103689- (2025)

Subject Terms: Biology (General), QH301-705.5

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Relation: http://www.sciencedirect.com/science/article/pii/S187350612500039X; https://doaj.org/toc/1873-5061

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Novel full-thickness biomimetic corneal model for studying pathogenesis and treatment of diabetic keratopathy

Authors: Zekai Cui, Xiaoxue Li, Yiwen Ou, Xihao Sun, Jianing Gu, Chengcheng Ding, Zhexiong Yu, Yonglong Guo, Yuqin Liang, Shengru Mao, Jacey Hongjie Ma, Hon Fai Chan, Shibo Tang, Jiansu Chen

Source: Materials Today Bio, Vol 30, Iss , Pp 101409- (2025)

Subject Terms: Diabetic keratopathy (DK), Biomimetic full-thickness corneal model, Lycium barbarum glycopeptide (LBGP), C-C motif chemokine ligand 5 (CCL5), Medicine (General), R5-920, Biology (General), QH301-705.5

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Relation: http://www.sciencedirect.com/science/article/pii/S2590006424004708; https://doaj.org/toc/2590-0064

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Generation of a gene-corrected isogenic human iPSC line (CSUASOi006-A-1) from a retinitis pigmentosa patient with heterozygous c.5792C > T mutation in the PRPF8 gene

Authors: Xihao Sun, Yuqin Liang, Chunwen Duan, Xujie Liu, Yalan Zhou, Shengru Mao, Zekai Cui, Jianing Gu, Chengcheng Ding, Jiansu Chen, Shibo Tang

Source: Stem Cell Research, Vol 81, Iss , Pp 103572- (2024)

Subject Terms: Biology (General), QH301-705.5

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Relation: http://www.sciencedirect.com/science/article/pii/S1873506124002708; https://doaj.org/toc/1873-5061

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Introduction of an RS1 mutation causative variant consistent with identified XLRS patient using CRISPR/Cas9 technology in normal iPSC

Authors: Xihao Sun, Shengru Mao, Yuqin Liang, Chunwen Duan, Zekai Cui, Jianing Gu, Bing Jiang, Chengcheng Ding, Jiansu Chen, Shibo Tang

Source: Stem Cell Research, Vol 81, Iss , Pp 103549- (2024)

Subject Terms: Biology (General), QH301-705.5

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Relation: http://www.sciencedirect.com/science/article/pii/S1873506124002472; https://doaj.org/toc/1873-5061

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A systematic review and meta-analysis of risk factors influencing patient-reported arm symptoms post-breast cancer treatment: Accounting for radiotherapy impact

Authors: Yuqin Liang, Yuedan Zhou, Ruud Houben, Karolien Verhoeven, Sofia Rivera, Liesbeth J. Boersma

Source: Breast, Vol 78, Iss , Pp 103812- (2024)

Subject Terms: Breast cancer, Patient-reported outcome measures, Arm symptom, Risk factor, Radiotherapy, Systematic review, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

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Relation: http://www.sciencedirect.com/science/article/pii/S0960977624001437; https://doaj.org/toc/1532-3080

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CRISPR/Cas9-mediated generation of a human induced pluripotent stem cell line with PRPF6 c.2699 G > A mutation to model retinitis pigmentosa

Authors: Yuqin Liang, Xihao Sun, Hang Chen, Zekai Cui, Jianing Gu, Chunwen Duan, Shengru Mao, Yuexi Chen, Xiaoxue Li, Siqi Xiong, Jiansu Chen

Source: Stem Cell Research, Vol 81, Iss , Pp 103581- (2024)

Subject Terms: Biology (General), QH301-705.5

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Relation: http://www.sciencedirect.com/science/article/pii/S1873506124002794; https://doaj.org/toc/1873-5061

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Integrated analysis of transcriptomics and metabolomics of garden asparagus (Asparagus officinalis L.) under drought stress

Authors: Xuhong Zhang, Changzhi Han, Yubo Wang, Tao Liu, Yuqin Liang, Yanpo Cao

Source: BMC Plant Biology, Vol 24, Iss 1, Pp 1-12 (2024)

Subject Terms: Drought stress, Transcriptome, Metabolome, Metabolic pathways, Asparagus, Botany, QK1-989

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Relation: https://doaj.org/toc/1471-2229

Access URL: https://doaj.org/article/705c87cb0603412d8cd668146e576fb3

Retinal organoids with X-linked retinoschisis RS1 (E72K) mutation exhibit a photoreceptor developmental delay and are rescued by gene augmentation therapy

Authors: Chunwen Duan, Chengcheng Ding, Xihao Sun, Shengru Mao, Yuqin Liang, Xinyu Liu, Xiaoyan Ding, Jiansu Chen, Shibo Tang

Source: Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2024)

Subject Terms: X-linked retinoschisis (XLRS), Retinal organoids (ROs), Human induced pluripotent stem cells (hiPSCs), Photoreceptor, Gene augmentation therapy, Medicine (General), R5-920, Biochemistry, QD415-436

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Relation: https://doaj.org/toc/1757-6512

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Calycosin improves atherosclerosis by reshaping the interaction between the gut microbiome and bile acid metabolism

Authors: Jiaqi Fu, Donghua Yu, Yuqin Liang, Xin Gao, Yunhe Shi, Yu Wang, Pingping Chen, Fang Lu, Shumin Liu

Source: Food Science and Human Wellness, Vol 14, Iss 4, p 9250085 (2025)

Subject Terms: calycosin, atherosderosis, bile acid metabolism, gut microbiota, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: https://www.sciopen.com/article/10.26599/FSHW.2024.9250085; https://doaj.org/toc/2097-0765; https://doaj.org/toc/2213-4530

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Efficient Fabrication of Human Corneal Stromal Cell Spheroids and Promoting Cell Stemness Based on 3D-Printed Derived PDMS Microwell Platform

Authors: Yuexi Chen, Jianing Gu, Zekai Cui, Xihao Sun, Yuqin Liang, Chunwen Duan, Xiaoxue Li, Zhanyu Su, Bo Zhang, Jiansu Chen, Zheng Wang

Source: Biomolecules, Vol 15, Iss 3, p 438 (2025)

Subject Terms: human corneal stromal cells, SMILE, three-dimensional spheroid culture, PDMS, stem cells, stemness, Microbiology, QR1-502

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Relation: https://www.mdpi.com/2218-273X/15/3/438; https://doaj.org/toc/2218-273X

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Application of patient-derived induced pluripotent stem cells and organoids in inherited retinal diseases

Authors: Yuqin Liang, Xihao Sun, Chunwen Duan, Shibo Tang, Jiansu Chen

Source: Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-17 (2023)

Subject Terms: Retinal organoid, Induced pluripotent stem cell, Inherited retinal disease, Disease modeling, Tissue engineering, Medicine (General), R5-920, Biochemistry, QD415-436

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Relation: https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/73c6d2f55c1a4bfe838a19bd77287ba5

Integration of 16S rRNA sequencing and metabolomics to investigate the modulatory effect of ginsenoside Rb1 on atherosclerosis

Authors: Yuqin Liang, Jiaqi Fu, Yunhe Shi, Xin Jiang, Fang Lu, Shumin Liu

Source: Heliyon, Vol 10, Iss 6, Pp e27597- (2024)

Subject Terms: Atherosclerosis, Ginsenoside Rb1, Inflammation, Gut microbiota, Short-chain fatty acid, Metabolomics, Science (General), Q1-390, Social sciences (General), H1-99

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Relation: http://www.sciencedirect.com/science/article/pii/S2405844024036284; https://doaj.org/toc/2405-8440

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Generation of a gene-corrected isogenic iPSC cell line from an X-linked retinoschisis patient with a hemizygous mutation c.304C > T (p.R102W) in RS1 gene

Authors: Shengru Mao, Xihao Sun, Chunwen Duan, Bing Jiang, Hongjie Ma, Shangli Ji, Yuqin Liang, Ruting Zhang, Jiansu Chen, Shibo Tang

Source: Stem Cell Research, Vol 73, Iss , Pp 103263- (2023)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1873506123002490; https://doaj.org/toc/1873-5061

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HuangQi ChiFeng decoction maintains gut microbiota and bile acid homeostasis through FXR signaling to improve atherosclerosis

Authors: Jiaqi Fu, Yuqin Liang, Yunhe Shi, Donghua Yu, Yu Wang, Pingping Chen, Shumin Liu, Fang Lu

Source: Heliyon, Vol 9, Iss 11, Pp e21935- (2023)

Subject Terms: Atherosclerosis, HQCFT, Bile acid, Gut microbiota, FXR, LXRα, Science (General), Q1-390, Social sciences (General), H1-99

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Relation: http://www.sciencedirect.com/science/article/pii/S2405844023091430; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/ce730e866d424ed4a0c364616f05586b

Combined full-length transcriptomic and metabolomic analysis reveals the regulatory mechanisms of adaptation to salt stress in asparagus

Authors: Xuhong Zhang, Changzhi Han, Yuqin Liang, Yang Yang, Yun Liu, Yanpo Cao

Source: Frontiers in Plant Science, Vol 13 (2022)

Subject Terms: salt stress, ion transport, metabolic adjustment, salinity tolerance, asparagus, Plant culture, SB1-1110

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fpls.2022.1050840/full; https://doaj.org/toc/1664-462X

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Generation of a gene-corrected human iPSC line (CSUASOi004-A-1) from a retinitis pigmentosa patient with heterozygous c.2699 G>A mutation in the PRPF6 gene

Authors: Yuqin Liang, Xihao Sun, Chunwen Duan, Yalan Zhou, Zekai Cui, Chengcheng Ding, Jianing Gu, Shengru Mao, Shangli Ji, Hon Fai Chan, Shibo Tang, Jiansu Chen

Source: Stem Cell Research, Vol 64, Iss , Pp 102911- (2022)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1873506122002604; https://doaj.org/toc/1873-5061

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Pre-Transplant Platelet Refractoriness and Alternative Donors Are Associated With Cytomegalovirus Retinitis in Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia

Authors: Yuehong Zhang, Yuqin Liang, Xu Zhang, Shunqing Wang, Jinpeng Cao, Zongyin Gao, Ling Li, Wenjian Mo

Source: Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)

Subject Terms: ocular infection, cytomegalovirus retinitis, hematopoietic stem cell transplantation, severe aplastic anemia, risk factor, Microbiology, QR1-502

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Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2022.870296/full; https://doaj.org/toc/2235-2988

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Establishment of a human induced pluripotent stem cell line (CSUASOi008-A) from a type 2 diabetic patient with retinopathy

Authors: Feng Tan, Chengcheng Ding, Xihao Sun, Yini Wang, Yu Peng, Yuqin Liang, Zhongping Chen, Shibo Tang, Jiansu Chen

Source: Stem Cell Research, Vol 59, Iss , Pp 102637- (2022)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1873506121004840; https://doaj.org/toc/1873-5061

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Comprehensive Evaluation of Salt Tolerance in Asparagus Germplasm Accessions (Asparagus officinalis L.) at Different Growth Stages

Authors: Huimin Gao, Xuhong Zhang, Yuqin Liang, Lingdi Dong, Changzhi Han, Yanpo Cao

Source: Journal of Food Quality, Vol 2021 (2021)

Subject Terms: Nutrition. Foods and food supply, TX341-641

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Relation: https://doaj.org/toc/0146-9428; https://doaj.org/toc/1745-4557

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The treatment and risk factors of retinopathy of prematurity in neonatal intensive care units

Authors: Yunxia Leng, Wenzhi Huang, Guoliang Ren, Cheng Cai, Qingbiao Tan, Yuqin Liang, Weizhong Yang, Zongyin Gao

Source: BMC Ophthalmology, Vol 18, Iss 1, Pp 1-8 (2018)

Subject Terms: Anti-VEGF, Neonatal intensive care unit/NICU, Retinopathy of prematurity/ROP, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12886-018-0973-1; https://doaj.org/toc/1471-2415

Access URL: https://doaj.org/article/473312180e224a40be856279955148be