Integrated multiomics signatures to optimize the accurate diagnosis of lung cancer

Authors: Mengmeng Zhao, Gang Xue, Bingxi He, Jiajun Deng, Tingting Wang, Yifan Zhong, Shenghui Li, Yang Wang, Yiming He, Tao Chen, Jun Zhang, Ziyue Yan, Xinlei Hu, Liuning Guo, Wendong Qu, Yongxiang Song, Minglei Yang, Guofang Zhao, Bentong Yu, Minjie Ma, Lunxu Liu, Xiwen Sun, Yunlang She, Dan Xie, Deping Zhao, Chang Chen

Source: Nature Communications, Vol 16, Iss 1, Pp 1-16 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/d64a9048c128445ab8737092ff591650

SNAI1 promotes epithelial-mesenchymal transition and maintains cancer stem cell-like properties in thymic epithelial tumors through the PIK3R2/p-EphA2 Axis

Authors: Haoran E, Lei Zhang, Zhenhua Yang, Long Xu, Tao Wang, Junhong Guo, Lang Xia, Juemin Yu, Heyong Wang, Yunlang She, Junqi Wu, Yue Zhao, Chang Chen, Deping Zhao

Source: Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)

Subject Terms: Thymic epithelial tumors, SNAI1, Epithelial-mesenchymal transition, Cancer stem cells, Phosphoinositide-3-kinase regulatory subunit 2 (PIK3R2), Phosphorylated EPH receptor A2 (p-EphA2), Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

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Prognostic Impact of Adjuvant Immunotherapy in Patients With Resectable NSCLC After Neoadjuvant Chemoimmunotherapy: A Brief Report

Authors: Yichen Dong, MD, Long Xu, MD, Jialiang Wen, MD, Haojie Si, MD, Juemin Yu, MD, Tao Chen, MD, Huikang Xie, MD, Xinjian Li, MD, Minglei Yang, MD, Junqiang Fan, MD, Junqi Wu, MD, Yunlang She, MD, Deping Zhao, MD, Chang Chen, MD, PhD

Source: JTO Clinical and Research Reports, Vol 6, Iss 1, Pp 100763- (2025)

Subject Terms: Non-small cell lung cancer, Neoadjuvant chemoimmunotherapy, Adjuvant immunotherapy, Perioperative immunotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

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Relation: http://www.sciencedirect.com/science/article/pii/S2666364324001334; https://doaj.org/toc/2666-3643

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PET/CT based cross-modal deep learning signature to predict occult nodal metastasis in lung cancer

Authors: Yifan Zhong, Chuang Cai, Tao Chen, Hao Gui, Jiajun Deng, Minglei Yang, Bentong Yu, Yongxiang Song, Tingting Wang, Xiwen Sun, Jingyun Shi, Yangchun Chen, Dong Xie, Chang Chen, Yunlang She

Source: Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/bd89d43617dd4e9e9206702ae1b48462

Prognostic Significance of the Proposed Residual Tumor Classification in Patients With NSCLC After Sleeve Lobectomy

Authors: Tao Chen, PhD, Yifan Zhong, PhD, Jialiang Wen, PhD, Jiajun Deng, PhD, Yunlang She, MD, Yuming Zhu, MD, Qiankun Chen, MD, Chunyan Wu, MD, Likun Hou, MD, Lei Jiang, MD, Chang Chen, MD, PhD

Source: JTO Clinical and Research Reports, Vol 4, Iss 10, Pp 100574- (2023)

Subject Terms: Residual tumor classification, UICC, IASLC, Sleeve lobectomy, Non–small cell lung cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666364323001170; https://doaj.org/toc/2666-3643

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Brief Report: Acetaminophen Reduces Neoadjuvant Chemoimmunotherapy Efficacy in Patients With NSCLC by Promoting Neutrophil Extracellular Trap Formation: Analysis From a Phase 2 Clinical Trial

Authors: Chongwu Li, MD, Junqi Wu, MD, Lei Zhang, MD, Fang Wang, MD, Long Xu, MD, Yue Zhao, MD, Yun Xiao, PhD, Fenghui Zhuang, MD, Likun Hou, MD, PhD, Deping Zhao, MD, PhD, Yunlang She, MD, PhD, Dong Xie, MD, PhD, Chang Chen, MD, PhD

Source: JTO Clinical and Research Reports, Vol 4, Iss 9, Pp 100556- (2023)

Subject Terms: Neoadjuvant, Immunotherapy, Lung cancer, Neutrophil extracellular traps, Proteomics, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666364323000991; https://doaj.org/toc/2666-3643

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Application of the Novel Grading System of Invasive Pulmonary Adenocarcinoma in a Real Diagnostic Scenario: A Brief Report of 9353 Cases

Authors: Yunlang She, MD, Yifan Zhong, MD, Likun Hou, MD, Shengnan Zhao, Liping Zhang, MD, Dong Xie, Yuming Zhu, MD, Chunyan Wu, MD, Chang Chen, MD

Source: JTO Clinical and Research Reports, Vol 4, Iss 3, Pp 100465- (2023)

Subject Terms: Lung adenocarcinoma, Grading system, Histological grade, Complex glands, EGFR mutation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666364323000048; https://doaj.org/toc/2666-3643

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The IASLC grading system for invasive pulmonary adenocarcinoma: a potential prognosticator for patients receiving neoadjuvant therapy

Authors: Haoran E, Junqi Wu, Yijiu Ren, Lang Xia, Long Xu, Shaoling Li, Yue Zhao, Chongwu Li, Yunlang She, Chunxia Su, Chunyan Wu, Likun Hou, Deping Zhao, Chang Chen

Source: Therapeutic Advances in Medical Oncology, Vol 15 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

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Relation: https://doaj.org/toc/1758-8359

Access URL: https://doaj.org/article/af4640557a184f0d878db0b6e68642fe

Deconstructing the intra-tumor subclonal heterogeneity of lung synchronous ground-glass nodules using whole-genome sequencing

Authors: Yijiu Ren, Minfang Song, Yunlang She, Huikang Xie, Hui Zheng, Chang Chen, Yiwen Zhang

Source: Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-3 (2022)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/a1f712c9a4814b1e9f290688dc709bbd

Deep learning for predicting major pathological response to neoadjuvant chemoimmunotherapy in non-small cell lung cancer: A multicentre studyResearch in context

Authors: Yunlang She, Bingxi He, Fang Wang, Yifan Zhong, Tingting Wang, Zhenchuan Liu, Minglei Yang, Bentong Yu, Jiajun Deng, Xiwen Sun, Chunyan Wu, Likun Hou, Yuming Zhu, Yang Yang, Hongjie Hu, Di Dong, Chang Chen, Jie Tian

Source: EBioMedicine, Vol 86, Iss , Pp 104364- (2022)

Subject Terms: Deep learning, Neoadjuvant chemoimmunotherapy, Major pathological response, Non-small cell lung cancer, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396422005461; https://doaj.org/toc/2352-3964

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Curcumin loaded polycaprolactone scaffold capable of anti-inflammation to enhance tracheal cartilage regeneration

Authors: Minglei Yang, Weiyan Sun, Long Wang, Hai Tang, Xiang Xu, Liangwei Yang, Junjun Ni, Kuoen Zheng, Xu Jiang, Weiwen Xu, Guofang Zhao, Yunlang She, Lei Zhang, Dong Xie, Chang Chen

Source: Materials & Design, Vol 224, Iss , Pp 111299- (2022)

Subject Terms: Curcumin, Anti-inflammation, Tracheal cartilage regeneration, Drug loading, Tissue engineering, Materials of engineering and construction. Mechanics of materials, TA401-492

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0264127522009212; https://doaj.org/toc/0264-1275

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Genopathomic profiling identifies signatures for immunotherapy response of lung adenocarcinoma via confounder-aware representation learning

Authors: Jiajun Deng, Jiancheng Yang, Likun Hou, Junqi Wu, Yi He, Mengmeng Zhao, Bingbing Ni, Donglai Wei, Hanspeter Pfister, Caicun Zhou, Tao Jiang, Yunlang She, Chunyan Wu, Chang Chen

Source: iScience, Vol 25, Iss 11, Pp 105382- (2022)

Subject Terms: Immunology, Cancer, Artificial intelligence, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004222016546; https://doaj.org/toc/2589-0042

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Early stage NSCLS patients’ prognostic prediction with multi-information using transformer and graph neural network model

Authors: Jie Lian, Jiajun Deng, Edward S Hui, Mohamad Koohi-Moghadam, Yunlang She, Chang Chen, Varut Vardhanabhuti

Source: eLife, Vol 11 (2022)

Subject Terms: lung cancer, medical imaging, transformer cnn, computed tomography, survival, prognostic model, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/80547; https://doaj.org/toc/2050-084X

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N6-methyladenosine-modified circIGF2BP3 inhibits CD8+ T-cell responses to facilitate tumor immune evasion by promoting the deubiquitination of PD-L1 in non-small cell lung cancer

Authors: Zhenchuan Liu, Tingting Wang, Yunlang She, Kaiqing Wu, Shaorui Gu, Lei Li, Chenglai Dong, Chang Chen, Yongxin Zhou

Source: Molecular Cancer, Vol 20, Iss 1, Pp 1-25 (2021)

Subject Terms: Circular RNA, Non-small-cell lung carcinoma, Plakophilin 3, PD-L1, Immune escape, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1476-4598

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Morphological Subtypes of Tumor Spread Through Air Spaces in Non-Small Cell Lung Cancer: Prognostic Heterogeneity and Its Underlying Mechanism

Authors: Huikang Xie, Hang Su, Erjia Zhu, Chang Gu, Shengnan Zhao, Yunlang She, Yijiu Ren, Dong Xie, Hui Zheng, Chunyan Wu, Chenyang Dai, Chang Chen

Source: Frontiers in Oncology, Vol 11 (2021)

Subject Terms: spread through air spaces, spread through a knife surface, non-small cell lung cancer, prognosis, artifact, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2021.608353/full; https://doaj.org/toc/2234-943X

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A Biomimetic Biphasic Scaffold Consisting of Decellularized Cartilage and Decalcified Bone Matrixes for Osteochondral Defect Repair

Authors: Runfeng Cao, Anqi Zhan, Zheng Ci, Cheng Wang, Yunlang She, Yong Xu, Kaiyan Xiao, Huitang Xia, Li Shen, Depeng Meng, Chang Chen

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: biphasic scaffold, decellularized cartilage matrix, decalcified bone matrix, osteochondral repair, tissue engineering, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.639006/full; https://doaj.org/toc/2296-634X

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3D Printed Biomimetic PCL Scaffold as Framework Interspersed With Collagen for Long Segment Tracheal Replacement

Authors: Yunlang She, Ziwen Fan, Long Wang, Yinze Li, Weiyan Sun, Hai Tang, Lei Zhang, Liang Wu, Hui Zheng, Chang Chen

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: biomimetic trachea development, ring structure, 3D-printing, tracheal replacement, mechanical property, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.629796/full; https://doaj.org/toc/2296-634X

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Bayesian network meta-analysis of efficacy and safety of neoadjuvant therapy for non-small-cell lung cancer

Authors: Yijiu Ren, Hai Tang, Jie Zhang, Yunlang She, Xiaoting Sun, Dong Xie, Chang Chen

Source: Therapeutic Advances in Medical Oncology, Vol 12 (2020)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1758-8359

Access URL: https://doaj.org/article/e4c6aa380b824dc69c4e10e75f5f9cfc

Is operation safe for lung cancer patients with interstitial lung disease on computed tomography?

Authors: Hai Tang, Yijiu Ren, Yunlang She, Chenyang Dai, Tingting Wang, Hang Su, Weiyan Sun, Gening Jiang, Chang Chen

Source: Therapeutic Advances in Respiratory Disease, Vol 14 (2020)

Subject Terms: Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/1753-4666

Access URL: https://doaj.org/article/e403c3291c904f8d96da97a029193dee

Predicting response to immunotherapy in advanced non-small-cell lung cancer using tumor mutational burden radiomic biomarker

Authors: Chang Chen, Jie Tian, Bingxi He, Di Dong, Yunlang She, Caicun Zhou, Mengjie Fang, Yongbei Zhu, Henghui Zhang, Zhipei Huang, Tao Jiang

Source: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/8/2/e000550.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/3858d690dda34be7b820000c91995601