Secretome from estrogen-responding human placenta-derived mesenchymal stem cells rescues ovarian function and circadian rhythm in mice with cyclophosphamide-induced primary ovarian insufficiency

Authors: Duy-Cuong Le, Mai-Huong T. Ngo, Yung-Che Kuo, Shu-Hwa Chen, Chung-Yen Lin, Thai-Yen Ling, Quoc Thao Trang Pham, Heng-Kien Au, Jihwan Myung, Yen-Hua Huang

Source: Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-29 (2024)

Subject Terms: Placenta mesenchymal stem cell, Estrogen receptor, Primary ovarian insufficiency, Ovarian circadian rhythm disorder, Angiogenin, Exosomal miRNA, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1423-0127

Access URL: https://doaj.org/article/0b97f6b1c17d4239a8ce8de9c3b219ea

A novel SEPT12 mutation, T96I, is associated with sperm head and annulus defects

Authors: Kuan-Ru Chen, Han-Yu Wang, Yung-Che Kuo, Yu-Chih Lo, Pao-Lin Kuo

Source: Frontiers in Cell and Developmental Biology, Vol 12 (2025)

Subject Terms: SEPTIN12, sperm head, sperm annulus, infertility, mutation, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2024.1498013/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/fe84e3ba07ab4607bb6ff9936b39d376

Corrigendum: Potential of cellular therapy for ALS: current strategies and future prospects

Authors: Ting-Jung Lin, Kuang-Chao Cheng, Luo-Yun Wu, Wei-Yu Lai, Thai-Yen Ling, Yung-Che Kuo, Yen-Hua Huang

Source: Frontiers in Cell and Developmental Biology, Vol 11 (2023)

Subject Terms: ALS, mesenchymal stem cell, motor neuron degeneration, precision medicine, cellular therapy, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2023.1292681/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/a8184208b0e9465797c170375baf485a

Potential of Cellular Therapy for ALS: Current Strategies and Future Prospects

Authors: Ting-Jung Lin, Kuang-Chao Cheng, Luo-Yun Wu, Wei-Yu Lai, Thai-Yen Ling, Yung-Che Kuo, Yen-Hua Huang

Source: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Subject Terms: ALS, mesenchymal stem cell, motor neuron degeneration, precision medicine, cellular therapy, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2022.851613/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/84e0dd7d35f14f70bdfc2b4543d85ee1

Vitiligo: An Autoimmune Skin Disease and its Immunomodulatory Therapeutic Intervention

Authors: Wei-Ling Chang, Woan-Ruoh Lee, Yung-Che Kuo, Yen-Hua Huang

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: vitiligo, autoimmune skin disorder, skin-resident memory T (TRM) cell, janus kinase, stem cell therapy, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.797026/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/e586801ac0f14fd6975ee4bf264facb6

DNMT3b/OCT4 expression confers sorafenib resistance and poor prognosis of hepatocellular carcinoma through IL-6/STAT3 regulation

Authors: Ssu-Chuan Lai, Yu-Ting Su, Ching-Chi Chi, Yung-Che Kuo, Kam-Fai Lee, Yu-Chih Wu, Pei-Chi Lan, Muh-Hwa Yang, Te-Sheng Chang, Yen-Hua Huang

Source: Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-18 (2019)

Subject Terms: Interleukin-6, Phospho-STAT3, OCT4, DNMT3b, Drug resistance, Hepatocellular carcinoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13046-019-1442-2; https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/81ffe598b12d460aa2b79bcea12cd258

Niche Laminin and IGF-1 Additively Coordinate the Maintenance of Oct-4 Through CD49f/IGF-1R-Hif-2α Feedforward Loop in Mouse Germline Stem Cells

Authors: Heng-Kien Au, Syue-Wei Peng, Chin-Lin Guo, Chien-Chia Lin, Yi-Lin Wang, Yung-Che Kuo, Tsz-Yau Law, Hong-Nerng Ho, Thai-Yen Ling, Yen-Hua Huang

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: germline stem cell, niche, extracellular matrix, hypoxia, laminin, IGF, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.646644/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/b689affe981b4728ba7db464478e1c2e

Niche Modulation of IGF-1R Signaling: Its Role in Stem Cell Pluripotency, Cancer Reprogramming, and Therapeutic Applications

Authors: Pei-Chin Chen, Yung-Che Kuo, Cheng-Ming Chuong, Yen-Hua Huang

Source: Frontiers in Cell and Developmental Biology, Vol 8 (2021)

Subject Terms: IGF-1R, niche, stem cells, cancer stemness, hypoxia, inflammation, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2020.625943/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/a75d660d66694309b76ac321a48383b0

IGF-1R Promotes Symmetric Self-Renewal and Migration of Alkaline Phosphatase+ Germ Stem Cells through HIF-2α-OCT4/CXCR4 Loop under Hypoxia

Authors: Yung-Che Kuo, Heng-Kien Au, Jue-Liang Hsu, Hsiao-Feng Wang, Chiung-Ju Lee, Syue-Wei Peng, Ssu-Chuan Lai, Yu-Chih Wu, Hong-Nerng Ho, Yen-Hua Huang

Source: Stem Cell Reports, Vol 10, Iss 2, Pp 524-537 (2018)

Subject Terms: Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213671117305519; https://doaj.org/toc/2213-6711

Access URL: https://doaj.org/article/43431158ae3d49b5b3fe4a80111fbc59

Correction to: DNMT3b/OCT4 expression confers sorafenib resistance and poor prognosis of hepatocellular carcinoma through IL-6/STAT3 regulation

Authors: Ssu-Chuan Lai, Yu-Ting Su, Ching-Chi Chi, Yung-Che Kuo, Kam-Fai Lee, Yu-Chih Wu, Pei-Chi Lan, Muh-Hwa Yang, Te-Sheng Chang, Yen-Hua Huang

Source: Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-2 (2020)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/cc590f14bbba44d28494b50c05fb1542

SEPT12 phosphorylation results in loss of the septin ring/sperm annulus, defective sperm motility and poor male fertility.

Authors: Yi-Ru Shen, Han-Yu Wang, Yung-Che Kuo, Shih-Chuan Shih, Chun-Hua Hsu, Yet-Ran Chen, Shang-Rung Wu, Chia-Yih Wang, Pao-Lin Kuo

Source: PLoS Genetics, Vol 13, Iss 3, p e1006631 (2017)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5386304?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/5d8d84d14b0b4ed6823364a9864a4899

TGF-βI Regulates Cell Migration through Pluripotent Transcription Factor OCT4 in Endometriosis.

Authors: Heng-Kien Au, Jui-Hung Chang, Yu-Chih Wu, Yung-Che Kuo, Yu-Hsi Chen, Wei-Chin Lee, Te-Sheng Chang, Pei-Chi Lan, Hung-Chih Kuo, Kha-Liang Lee, Mei-Tsu Lee, Chii-Ruey Tzeng, Yen-Hua Huang

Source: PLoS ONE, Vol 10, Iss 12, p e0145256 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0145256&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/caa58997ece848b2931968a4befed290

SEPTIN12 genetic variants confer susceptibility to teratozoospermia.

Authors: Ying-Hung Lin, Ya-Yun Wang, Hau-Inh Chen, Yung-Che Kuo, Yu-Wei Chiou, Hsi-Hui Lin, Ching-Ming Wu, Chao-Chin Hsu, Han-Sun Chiang, Pao-Lin Kuo

Source: PLoS ONE, Vol 7, Iss 3, p e34011 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3316533?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/dd3d92c44a5f41e083339717ea3c4770

SEPT12-Microtubule Complexes Are Required for Sperm Head and Tail Formation.

Authors: Pao-Lin Kuo, Han-Sun Chiang, Ya-Yun Wang, Yung-Che Kuo, Mei-Feng Chen, I-Shing Yu, Yen-Ni Teng, Shu-Wha Lin, Ying-Hung Lin

Source: International Journal of Molecular Sciences; Nov2013, Vol. 14 Issue 11, p22102-22116, 17p

Subject Terms: MICROTUBULES, SPERMATOZOA, SEPTINS, CYTOSKELETAL proteins, G proteins, POLYMERIZATION, CELL morphology

The role of the septin family in spermiogenesis.

Authors: Ying-Hung Lin¹, Yung-Che Kuo², Han-Sun Chiang^1,3, Pao-Lin Kuo^2,4 paolink@mail.ncku.edu.tw

Source: Spermatogenesis. Oct2011, Vol. 1 Issue 4, p298-302. 5p.

Subject Terms: *SEPTINS, *G proteins, *CELL physiology, *TESTIS, *MALE infertility, *SPERMATOGENESIS

The expression pattern of SEPT7 correlates with sperm morphology.

Authors: Hsin-Chih Albert Chao, Ying-Hung Lin, Yung-Che Kuo, Chiung-Jiung Shen, Hsian-Ann Pan, Pao-Lin Kuo

Source: Journal of Assisted Reproduction & Genetics; Jun2010, Vol. 27 Issue 6, p299-307, 9p

Subject Terms: SPERMATOGENESIS, PROTEINS, SPERMATOZOA, IMMUNOFLUORESCENCE, SEMEN

Correction: Inflammation Promotes Expression of Stemness-Related Properties in HBV-Related Hepatocellular Carcinoma.

Authors: Te-Sheng Chang, Chi-Long Chen, Yu-Chih Wu, Jun-Jen Liu, Yung Che Kuo, Kam-Fai Lee, Sin-Yi Lin, Sey-En Lin, Shui-Yi Tung, Liang-Mou Kuo, Ying-Huang Tsai, Yen-Hua Huang

Source: PLoS ONE, Vol 12, Iss 1, p e0171176 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5268363?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/dca0e74828034dd7a036b69d96831e2b

Inflammation Promotes Expression of Stemness-Related Properties in HBV-Related Hepatocellular Carcinoma.

Authors: Te-Sheng Chang, Chi-Long Chen, Yu-Chih Wu, Jun-Jen Liu, Yung Che Kuo, Kam-Fai Lee, Sin-Yi Lin, Sey-En Lin, Shui-Yi Tung, Liang-Mou Kuo, Ying-Huang Tsai, Yen-Hua Huang

Source: PLoS ONE, Vol 11, Iss 2, p e0149897 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4769282?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/75a3073c025b4b318dcbd2aaee3ba995