Ginsenoside Rg1 Regulates Immune Microenvironment and Neurological Recovery After Spinal Cord Injury Through MYCBP2 Delivery via Neuronal Cell‐Derived Extracellular Vesicles

Authors: Yuluo Rong, Jiaxing Wang, Tao Hu, Zhongming Shi, Chuandong Lang, Wei Liu, Weihua Cai, Yongjin Sun, Feng Zhang, Wenzhi Zhang

Source: Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)

Subject Terms: extracellular vesicles, ginsenoside Rg1, microglial polarization, MYCBP2/S100A9 axis, oxidative stress, spinal cord injury, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/2c00a71a026642048f343f0a79dc8bc3

Engineered extracellular vesicles for delivery of siRNA promoting targeted repair of traumatic spinal cord injury

Authors: Yuluo Rong, Zhuanghui Wang, Pengyu Tang, Jiaxing Wang, Chengyue Ji, Jie Chang, Yufeng Zhu, Wu Ye, Jianling Bai, Wei Liu, Guoyong Yin, Lipeng Yu, Xuhui Zhou, Weihua Cai

Source: Bioactive Materials, Vol 23, Iss , Pp 328-342 (2023)

Subject Terms: Extracellular vesicles, Spinal cord injury, siRNA, Microglia/macrophages polarization, Induced neural stem cells, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X22004753; https://doaj.org/toc/2452-199X

Access URL: https://doaj.org/article/fbfdf5bc8d454119bc9b1cd2763f9c7a

Small extracellular vesicles encapsulating CCL2 from activated astrocytes induce microglial activation and neuronal apoptosis after traumatic spinal cord injury

Authors: Yuluo Rong, Chengyue Ji, Zhuanghui Wang, Xuhui Ge, Jiaxing Wang, Wu Ye, Pengyu Tang, Dongdong Jiang, Jin Fan, Guoyong Yin, Wei Liu, Weihua Cai

Source: Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-20 (2021)

Subject Terms: Spinal cord injury, Astrocyte, Small extracellular vesicles, CCL2, Microglia, Neuron, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/4bef46187d4e463b94e51e82bf0d794e

Correction to: Small extracellular vesicles encapsulating CCL2 from activated astrocytes induce microglial activation and neuronal apoptosis after traumatic spinal cord injury

Authors: Yuluo Rong, Chengyue Ji, Zhuanghui Wang, Xuhui Ge, Jiaxing Wang, Wu Ye, Pengyu Tang, Dongdong Jiang, Jin Fan, Guoyong Yin, Wei Liu, Weihua Cai

Source: Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-3 (2021)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/98c0514dad9e45f9956c18cd9483540f

Establishment of a nomogram for predicting the surgical difficulty of anterior cervical spine surgery

Authors: Chengyue Ji, Yuluo Rong, Jiaxing Wang, Guoyong Yin, Jin Fan, Pengyu Tang, Dongdong Jiang, Wei Liu, Xuhui Ge, Shunzhi Yu, Weihua Cai

Source: BMC Surgery, Vol 21, Iss 1, Pp 1-7 (2021)

Subject Terms: Surgical difficulty, Anterior cervical spine surgery, Nomogram, Surgery, RD1-811

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2482

Access URL: https://doaj.org/article/737be455f0024e45bf37e3033d30bba5

Exosomal Transfer of LCP1 Promotes Osteosarcoma Cell Tumorigenesis and Metastasis by Activating the JAK2/STAT3 Signaling Pathway

Authors: Xuhui Ge, Wei Liu, Wene Zhao, Shuang Feng, Ao Duan, Chengyue Ji, Kai Shen, Wanshun Liu, Jiawen Zhou, Dongdong Jiang, Yuluo Rong, Fangyi Gong, Jiaxing Wang, Zhiyang Xu, Xiaoyan Li, Jin Fan, Yongzhong Wei, Jianling Bai, Weihua Cai

Source: Molecular Therapy: Nucleic Acids, Vol 21, Iss , Pp 900-915 (2020)

Subject Terms: osteosarcoma, exosomal LCP1, BMSCs, miR-135a-5p, JAK2/STAT3 pathway, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253120302146; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/0ae25f72e0c6402face4c6e8ab6ae9cd

Neuron-derived exosomes-transmitted miR-124-3p protect traumatically injured spinal cord by suppressing the activation of neurotoxic microglia and astrocytes

Authors: Dongdong Jiang, Fangyi Gong, Xuhui Ge, Chengtang Lv, Chenyu Huang, Shuang Feng, Zheng Zhou, Yuluo Rong, Jiaxing Wang, Chengyue Ji, Jian Chen, Wene Zhao, Jin Fan, Wei Liu, Weihua Cai

Source: Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-20 (2020)

Subject Terms: Spinal cord injury, Exosomes, Microglia, Astrocytes, miR-124-3p/MYH9 axis, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12951-020-00665-8; https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/38613806035943af9934d30e2a20ed93

MicroRNA-421-3p-abundant small extracellular vesicles derived from M2 bone marrow-derived macrophages attenuate apoptosis and promote motor function recovery via inhibition of mTOR in spinal cord injury

Authors: Jiaxing Wang, Yuluo Rong, Chengyue Ji, Chengtang Lv, Dongdong Jiang, Xuhui Ge, Fangyi Gong, Pengyu Tang, Weihua Cai, Wei Liu, Jin Fan

Source: Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-17 (2020)

Subject Terms: Autophagy, Bone marrow-derived macrophage, mTOR, Spinal cord injury, Small extracellular vesicle, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12951-020-00630-5; https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/1e19f19c2f4343a698d645b09628e1ef

Corrigendum to 'Exosomal miR-155 from M1-polarized macrophages promotes EndoMT and impairs mitochondrial function via activating NF-κB signaling pathway in vascular endothelial cells after traumatic spinal cord injury' [Redox Biol. 41 (2021) 101932/PMID:33714739]

Authors: Xuhui Ge, Pengyu Tang, Yuluo Rong, Dongdong Jiang, Xiao Lu, Chengyue Ji, Jiaxing Wang, Chenyu Huang, Ao Duan, Yang Liu, Xinglin Chen, Xichen Chen, Zhiyang Xu, Feng Wang, Zibin Wang, Xiaoyan Li, Wene Zhao, Jin Fan, Weihua Cai, Guoyong Yin, Wei Liu

Source: Redox Biology, Vol 47, Iss , Pp 102121- (2021)

Subject Terms: Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231721002809; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/2f7c934b461c4a6db82bdd3e04492bce

Exosome-shuttled miR-216a-5p from hypoxic preconditioned mesenchymal stem cells repair traumatic spinal cord injury by shifting microglial M1/M2 polarization

Authors: Wei Liu, Yuluo Rong, Jiaxing Wang, Zheng Zhou, Xuhui Ge, Chengyue Ji, Dongdong Jiang, Fangyi Gong, Linwei Li, Jian Chen, Shujie Zhao, Fanqi Kong, Changjiang Gu, Jin Fan, Weihua Cai

Source: Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-22 (2020)

Subject Terms: Spinal cord injury, Exosomes, Hypoxia, Microglia polarization, miR-216a-5p/TLR4 axis, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/e1b2b1fed81d474194e4fa0e4a37d9d7

miR-624-5p promoted tumorigenesis and metastasis by suppressing hippo signaling through targeting PTPRB in osteosarcoma cells

Authors: Yongjun Luo, Wei Liu, Pengyu Tang, Dongdong Jiang, Changjiang Gu, Yumin Huang, Fangyi Gong, Yuluo Rong, Dingfei Qian, Jian Chen, Zheng Zhou, Shujie Zhao, Jiaxing Wang, Tao Xu, Yongzhong Wei, Guoyong Yin, Jin Fan, Weihua Cai

Source: Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)

Subject Terms: Osteosarcoma, miR-624-5p, PTPRB, Hippo, Metastasis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/4dd3eb91e98d4f9ba60604bc0546eee6

Exosomal miR-155 from M1-polarized macrophages promotes EndoMT and impairs mitochondrial function via activating NF-κB signaling pathway in vascular endothelial cells after traumatic spinal cord injury

Authors: Xuhui Ge, Pengyu Tang, Yuluo Rong, Dongdong Jiang, Xiao Lu, Chengyue Ji, Jiaxing Wang, Chenyu Huang, Ao Duan, Yang Liu, Xinglin Chen, Xichen Chen, Zhiyang Xu, Feng Wang, Zibin Wang, Xiaoyan Li, Wene Zhao, Jin Fan, Wei Liu, Guoyong Yin, Weihua Cai

Source: Redox Biology, Vol 41, Iss , Pp 101932- (2021)

Subject Terms: Spinal cord injury, Blood-spinal-cord-barrier, miR-155/SOCS6/p65, Endothelial-to-mesenchymal transition, Mitochondria, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S221323172100080X; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/4b1d4977c9cf4f918f0aaf7549aa323c

SEPHS1 attenuates intervertebral disc degeneration by delaying nucleus pulposus cell senescence through the Hippo-Yap/Taz pathway.

Authors: Tao Hu, Zhongming Shi, Yongjin Sun, Feng Hu, Yuluo Rong, Jia Wang, Liang Wang, Wenbin Xu, Feng Zhang, Wen-Zhi Zhang

Source: American Journal of Physiology: Cell Physiology; Feb2024, Vol. 326 Issue 2, pC386-C399, 14p

Subject Terms: NUCLEUS pulposus, INTERVERTEBRAL disk, REACTIVE oxygen species, EXTRACELLULAR matrix, OXIDATIVE stress, CELLULAR aging

Deubiquitinase UCHL1 promotes angiogenesis and blood–spinal cord barrier function recovery after spinal cord injury by stabilizing Sox17.

Authors: Jiaxing Wang, Chengyue Ji, Wu Ye, Yuluo Rong, Xuhui Ge, Zhuanghui Wang, Pengyu Tang, Zheng Zhou, Yongjun Luo, Weihua Cai

Source: Cellular & Molecular Life Sciences; Jan2024, Vol. 81 Issue 1, p1-16, 16p, 7 Graphs

Risk Factors for Refracture following Primary Osteoporotic Vertebral Compression Fractures.

Authors: Chengyue Ji, Yuluo Rong, Jiaxing Wang, Shunzhi Yu, Guoyong Yin, Jin Fan, Pengyu Tang, Dongdong Jiang, Wei Liu, Fangyi Gong, Xuhui Ge, Weihua Cai

Source: Pain Physician; May2021, Vol. 24 Issue 3, pE335-E340, 6p

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