Inhibition of CDCP1 by 8‐isopentenylnaringenin synergizes with EGFR inhibitors in lung cancer treatment

Authors: Sze‐Ching Wong, Chun‐Chieh Yeh, Xun‐Yu Zhang, Chih‐Ying Hsieh, Chia‐Chien Lo, Ting‐Ting Kuo, Ching‐Chan Lin, Chih‐Hua Chao, Jing‐Pei Liu, Ling‐Chu Chang, Lu‐Hai Wang, Yuh‐Pyng Sher

Source: Molecular Oncology, Vol 17, Iss 8, Pp 1648-1665 (2023)

Subject Terms: 8‐isopentenylnaringenin, EGFR TKI acquired resistance, lung adenocarcinoma, necrosis, synergistic effects, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/353ae90eeedf4b26a5791f7b425b5f6c

A disintegrin and metalloproteinase domain 9 facilitates SARS-CoV-2 entry into cells with low ACE2 expression

Authors: Ivonne Melano, Wei-Chung Cheng, Li-Lan Kuo, Yuag-Meng Liu, Yu Chi Chou, Mien-Chie Hung, Michael M. C. Lai, Yuh-Pyng Sher, Wen-Chi Su

Source: Microbiology Spectrum, Vol 11, Iss 5 (2023)

Subject Terms: SARS-CoV-2, coronavirus, virus entry, virus-host interactions, infectious disease, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/019f88b4e76647a19ada77ea39f4d35e

Using bioinformatics approaches to identify survival-related oncomiRs as potential targets of miRNA-based treatments for lung adenocarcinoma

Authors: Chia-Hsin Liu, Shu-Hsuan Liu, Yo-Liang Lai, Yi-Chun Cho, Fang-Hsin Chen, Li-Jie Lin, Pei-Hua Peng, Chia-Yang Li, Shu-Chi Wang, Ji-Lin Chen, Heng-Hsiung Wu, Min-Zu Wu, Yuh-Pyng Sher, Wei-Chung Cheng, Kai-Wen Hsu

Source: Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 4626-4635 (2022)

Subject Terms: oncomiR, antagomiR, Lung adenocarcinoma, miRNA treatment, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2001037022003762; https://doaj.org/toc/2001-0370

Access URL: https://doaj.org/article/0142da904d0e48d8bb1bb3790a3773d0

Systematic identification of clinically relevant miRNAs for potential miRNA-based therapy in lung adenocarcinoma

Authors: Shu-Hsuan Liu, Kai-Wen Hsu, Yo-Liang Lai, Yu-Feng Lin, Fang-Hsin Chen, Pei-Hwa Peng, Li-Jie Lin, Heng-Hsiung Wu, Chia-Yang Li, Shu-Chi Wang, Min-Zu Wu, Yuh-Pyng Sher, Wei-Chung Cheng

Source: Molecular Therapy: Nucleic Acids, Vol 25, Iss , Pp 1-10 (2021)

Subject Terms: lung adenocarcinoma, miRNA, therapy, nucleotide drug, miRNA mimics, additive effect, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253121001141; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/cd747dbc44cd48deb46fab9b2c4a9054

EFHD2 contributes to non-small cell lung cancer cisplatin resistance by the activation of NOX4-ROS-ABCC1 axis

Authors: Chi-Chen Fan, Sheng-Ta Tsai, Chen-Yuan Lin, Ling-Chu Chang, Juan-Cheng Yang, Guan‐Yu Chen, Yuh-Pyng Sher, Shao-Chun Wang, Michael Hsiao, Wei‐Chao Chang

Source: Redox Biology, Vol 34, Iss , Pp 101571- (2020)

Subject Terms: EFHD2, Recurrence, Adjuvant chemotherapy, NOX4, ABCC1, Ibuprofen, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231720303785; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/6417aba6fe7e4f2d9cc2fcb446d63216

A Polypeptide of Tumor-Associated Antigen L6 with Intrinsic Adjuvant Activity Enhances Antitumor Immunity

Authors: Yuh-Pyng Sher, Kit Man Chai, Wen-Ching Chen, Kuan-Yin Shen, I-Hua Chen, Ming-Hui Lee, Fang-Feng Chiu, Shih-Jen Liu

Source: Vaccines, Vol 8, Iss 4, p 620 (2020)

Subject Terms: TAL6, lipoprotein, TLR2, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/8/4/620; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/3e0533cbf3fc4e7f96b97b4f51816749

Immunological evaluation of a novel HLA-A2 restricted phosphopeptide of tumor associated Antigen, TRAP1, on cancer therapy

Authors: Min-Han Lin, Kuan-Yin Shen, Bing-Sin Liu, I-Hua Chen, Yuh-Pyng Sher, Guan-Chin Tseng, Shih-Jen Liu, Wang-Chou Sung

Source: Vaccine: X, Vol 1, Iss , Pp - (2019)

Subject Terms: Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S259013621930018X; https://doaj.org/toc/2590-1362

Access URL: https://doaj.org/article/2370a381490241f6bca9c8221dc4d70f

ADAM9 up-regulates N-cadherin via miR-218 suppression in lung adenocarcinoma cells.

Authors: Yuh-Pyng Sher, Li-Ju Wang, Li-Ling Chuang, Mong-Hsun Tsai, Ting-Ting Kuo, Cheng-Chung Huang, Eric Y Chuang, Liang-Chuan Lai

Source: PLoS ONE, Vol 9, Iss 4, p e94065 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094065&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/3b0995927740413e8ac41d38082dcfcd

Blood AST, ALT and UREA/BUN Level Analysis

Authors: Yuh-Pyng Sher, Mien-Chie Hung

Source: Bio-Protocol, Vol 3, Iss 19 (2013)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://bio-protocol.org/en/bpdetail?id=931&type=0; https://doaj.org/toc/2331-8325

Access URL: https://doaj.org/article/cd8d2849215c461590fa56aeb0da941f

Down-regulation of NDRG1 promotes migration of cancer cells during reoxygenation.

Authors: Liang-Chuan Lai, Yi-Yu Su, Kuo-Chih Chen, Mong-Hsun Tsai, Yuh-Pyng Sher, Tzu-Pin Lu, Chien-Yueh Lee, Eric Y Chuang

Source: PLoS ONE, Vol 6, Iss 8, p e24375 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21912630/pdf/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/5051598b334d409e998b0c9d7bce035c

ADAM9 functions as a transcriptional regulator to drive angiogenesis in esophageal squamous cell carcinoma.

Authors: Yu-Sen Lin, Ting-Ting Kuo, Chia-Chien Lo, Wei-Chung Cheng, Wei-Chao Chang, Guan-Chin Tseng, Shih-Ting Bai, Yu-Kai Huang, Chih-Ying Hsieh, Han-Shui Hsu, Yi-Fan Jiang, Chen-Yuan Lin, Liang-Chuan Lai, Xing-Guo Li, Yuh-Pyng Sher

Source: International Journal of Biological Sciences; 2021, Vol. 17 Issue 14, p3898-3910, 13p

Identification of theranostic factors for patients developing metastasis after surgery for early-stage lung adenocarcinoma.

Authors: Wei-Chung Cheng, Chun-Yu Chang, Chia-Chien Lo, Chih-Ying Hsieh, Ting-Ting Kuo, Guan-Chin Tseng, Sze-Ching Wong, Shu-Fen Chiang, Chih-Yang Huang, Kevin, Liang-Chuan Lai, Tzu-Pin Lu, Chao, K. S. Clifford, Yuh-Pyng Sher

Source: Theranostics; 2021, Vol. 11 Issue 8, p3661-3675, 15p

MicroRNA-769-3p Down-regulates NDRG1 and Enhances Apoptosis in MCF-7 Cells During Reoxygenation.

Authors: En-Ching Luo, Ya-Chu Chang, Yuh-Pyng Sher, Wei-Yung Huang, Li-Ling Chuang, Yu-Chiao Chiu, Mong-Hsun Tsai, Chuang, Eric Y., Liang-Chuan Lai

Source: Scientific Reports; 8/1/2014, p1-8, 8p

Subject Terms: MICRORNA, APOPTOSIS, TUMORS, OXIDATIVE stress, CELL proliferation

Matching gene activity with physiological functions.

Authors: Wei Huang, Yuh-Pyng Sher, Peck, Konan, Fung, Yuan Cheng B.

Source: Proceedings of the National Academy of Sciences of the United States of America. 3/5/2002, Vol. 99 Issue 5, p2603. 6p. 4 Charts, 9 Graphs.

Subject Terms: *GENES, *DNA microarrays, *PULMONARY artery

ADAM9 Promotes Lung Cancer Metastases to Brain by a Plasminogen Activator-Based Pathway.

Authors: Chen-Yuan Lin^1,2, Hung-Jen Chen³, Cheng-Chung Huang⁴, Liang-Chuan Lai⁵, Tzu-Pin Lu⁶, Guan-Chin Tseng⁷, Ting-Ting Kuo⁴, Qian-Yu Kuok⁴, Jennifer L. Hsu^4,8,9, Shian-Ying Sung¹⁰, Mien-Chie Hung^4,9,11,12 mhung@mdanderson.org, Yuh-Pyng Sher^1,4 ypsher@mail.cmu.edu.tw

Source: Cancer Research. 9/15/2014, Vol. 74 Issue 18, p5229-5243. 15p.

Subject Terms: *MEMBRANE proteins, *INTEGRINS, *CANCER cell migration, *LUNG cancer, *PLASMINOGEN activators

Anti-IFN-γ autoantibodies in adults with disseminated nontuberculous mycobacterial infections are associated with HLA-DRB1* 16:02 and HLA-DQB1 *05:02 and the reactivation of latent varicella-zoster virus infection.

Authors: Chih-Yu Chi^1,2, Chen-chung Chu^3,4, Jing-Pei Liu⁵, Chia-Hao Lin^5,6, Mao-Wang Ho², Wen-Jyi Lo⁷, Po-Chang Lin², Hung-Jen Chen^8,9, Chia-Huei Chou², Jia-Yih Feng^10,11, Chang-Phone Fung¹², Yuh-Pyng Sher^1,13, Chi-Yuan Li¹, Jen-Hsien Wang², Cheng-Lung Ku^1,5 clku@mail.cgu.edu.tw

Source: Blood. 2/21/2013, Vol. 121 Issue 8, p1357-1366. 10p.

Subject Terms: *AUTOANTIBODIES, *AUTOIMMUNE diseases, *MYCOBACTERIAL diseases, *VARICELLA-zoster virus diseases, *IMMUNOLOGIC diseases, *SALMONELLA diseases

Nuclear ErbB2 Enhances Translation and Cell Growth by Activating Transcription of Ribosomal RNA Genes.

Authors: Long-Yuan Li^1,2,3,4 mhung@mdanderson.org, Hsiuyi Chen^1,2, Yi-Hsien Hsieh¹, Ying-Nai Wang⁵, Hsiao-Ju Chu^1,2, Ya-Huey Chen¹, Hui-Yu Chen^1,2, Peng-Ju Chien^1,2, Haou-Tzong Ma³, Ho-Cheng Tsai^1,2, Chien-Chen Lai^1,6, Yuh-Pyng Sher¹, Huang-Chun Lien⁷, Chang-Hai Tsai^1,4, Mien-Chie Hung^1,2,5

Source: Cancer Research. Jun2011, Vol. 71 Issue 12, p4269-4279. 11p.

Subject Terms: *CARCINOGENESIS, *GROWTH factors, *RNA polymerases, *CANCER invasiveness, *CHROMATIN