IDH2 mutation accelerates TPO‐induced myelofibrosis with enhanced S100a8/a9 and NFκB signaling in vivo

Authors: Chien‐Chin Lin, Chi‐Yuan Yao, Yu‐Hung Wang, Yueh‐Chwen Hsu, Chang‐Tsu Yuan, Tsung‐Chih Chen, Chia‐Lang Hsu, Sze‐Hwei Lee, Jhih‐Yi Lee, Pin‐Tsen Shih, Chein‐Jun Kao, Po‐Han Chuang, Yuan‐Yeh Kuo, Hsin‐An Hou, Wen‐Chien Chou, Hwei‐Fang Tien

Source: eJHaem, Vol 5, Iss 4, Pp 738-748 (2024)

Subject Terms: IDH2 mutation, myelofibrosis, S100a8/a9, TPO, Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/2688-6146

Access URL: https://doaj.org/article/fa92d941b488439f9510b04086ba0152

Comparison of the 2022 world health organization classification and international consensus classification in myelodysplastic syndromes/neoplasms

Authors: Wan-Hsuan Lee, Chien-Chin Lin, Cheng-Hong Tsai, Feng-Ming Tien, Min-Yen Lo, Mei-Hsuan Tseng, Yuan-Yeh Kuo, Shan-Chi Yu, Ming-Chih Liu, Chang-Tsu Yuan, Yi-Tsung Yang, Ming-Kai Chuang, Bor-Sheng Ko, Jih-Luh Tang, Hsun-I Sun, Yi-Kuang Chuang, Hwei-Fang Tien, Hsin-An Hou, Wen-Chien Chou

Source: Blood Cancer Journal, Vol 14, Iss 1, Pp 1-11 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2044-5385

Access URL: https://doaj.org/article/08649900302e45c9bf674e6a825aabb4

Dysregulated immune and metabolic pathways are associated with poor survival in adult acute myeloid leukemia with CEBPA bZIP in-frame mutations

Authors: Feng-Ming Tien, Chi-Yuan Yao, Xavier Cheng-Hong Tsai, Min-Yen Lo, Chien-Yuan Chen, Wan-Hsuan Lee, Chien-Chin Lin, Yuan-Yeh Kuo, Yen-Ling Peng, Mei-Hsuan Tseng, Yu-Sin Wu, Ming-Chih Liu, Liang-In Lin, Ming-Kai Chuang, Bor-Sheng Ko, Ming Yao, Jih-Luh Tang, Wen-Chien Chou, Hsin-An Hou, Hwei-Fang Tien

Source: Blood Cancer Journal, Vol 14, Iss 1, Pp 1-10 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2044-5385

Access URL: https://doaj.org/article/a473b9ab2e6e4571988c16d2b5a68bfe

Validation of the molecular international prognostic scoring system in patients with myelodysplastic syndromes defined by international consensus classification

Authors: Wan-Hsuan Lee, Ming-Tao Tsai, Cheng-Hong Tsai, Feng-Ming Tien, Min-Yen Lo, Mei-Hsuan Tseng, Yuan-Yeh Kuo, Ming-Chih Liu, Yi-Tsung Yang, Jui-Che Chen, Jih-Luh Tang, Hsun-I Sun, Yi-Kuang Chuang, Liang-In Lin, Wen-Chien Chou, Chien-Chin Lin, Hsin-An Hou, Hwei-Fang Tien

Source: Blood Cancer Journal, Vol 13, Iss 1, Pp 1-8 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2044-5385

Access URL: https://doaj.org/article/7479abc62de646a98b87cad2d66ca5e0

Poor prognostic implications of myelodysplasia-related mutations in both older and younger patients with de novo AML

Authors: Xavier Cheng-Hong Tsai, Kuo-Jui Sun, Min-Yen Lo, Feng-Ming Tien, Yuan-Yeh Kuo, Mei-Hsuan Tseng, Yen-Ling Peng, Yi-Kuang Chuang, Bor-Sheng Ko, Jih-Luh Tang, Hsun-I Sun, Ming-Chih Liu, Chia-Wen Liu, Chien-Chin Lin, Ming Yao, Wen-Chien Chou, Hsin-An Hou, Hwei-Fang Tien

Source: Blood Cancer Journal, Vol 13, Iss 1, Pp 1-11 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2044-5385

Access URL: https://doaj.org/article/b596d2b3efd1497b8eea73005ee3a8d3

P721: VALIDATION OF THE MOLECULAR INTERNATIONAL PROGNOSTIC SCORING SYSTEM IN PATIENTS WITH MYELODYSPLASTIC SYNDROMES DEFINED BY INTERNATIONAL CONSENSUS CLASSIFICATION

Authors: Wan Hsuan Lee, Ming-Daw Tsai, Chien-Chin Lin, Cheng-Hong Tsai, Feng-Ming Tien, Min-Yen Lo, Mei-Hsuan Tseng, Yuan-Yeh Kuo, Ming-Chih Liu, Jih-Luh Tang, Hsun -I Sun, Yi-Kuang Chuang, Wen-Chien Chou, Hsin-An Hou, Hwei-Fang Tien

Source: HemaSphere, Vol 7, p e4348711 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/01.HS9.0000969788.43487.11; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/c694affdd9594caeab76299a2a7a35c5

Incorporation of long non-coding RNA expression profile in the 2017 ELN risk classification can improve prognostic prediction of acute myeloid leukemia patientsResearch in context

Authors: Cheng-Hong Tsai, Chi-Yuan Yao, Feng-Min Tien, Jih-Luh Tang, Yuan-Yeh Kuo, Yu-Chiao Chiu, Chien-Chin Lin, Mei-Hsuan Tseng, Yen-Ling Peng, Ming-Chih Liu, Chia-Wen Liu, Ming Yao, Liang-In Lin, Wen-Chien Chou, Chien-Yu Chen, Hsin-An Hou, Hwei-Fang Tien

Source: EBioMedicine, Vol 40, Iss , Pp 240-250 (2019)

Subject Terms: Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396419300271; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/9408d3a4d7ab488fb4e6d2b8f6f08a36

Dynamics of DNMT3A mutation and prognostic relevance in patients with primary myelodysplastic syndrome

Authors: Ming-En Lin, Hsin-An Hou, Cheng-Hong Tsai, Shang-Ju Wu, Yuan-Yeh Kuo, Mei-Hsuan Tseng, Ming-Chih Liu, Chia-Wen Liu, Wen-Chien Chou, Chien-Yuan Chen, Jih-Luh Tang, Ming Yao, Chi-Cheng Li, Shang-Yi Huang, Bor-Sheng Ko, Szu-Chun Hsu, Chien-Ting Lin, Hwei-Fang Tien

Source: Clinical Epigenetics, Vol 10, Iss 1, Pp 1-12 (2018)

Subject Terms: DNMT3A, Myelodysplastic syndrome, Prognosis, Paired samples, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13148-018-0476-1; https://doaj.org/toc/1868-7075; https://doaj.org/toc/1868-7083

Access URL: https://doaj.org/article/1b2f6646e739435697f12ad50dbf6887

The distinct biological implications of Asxl1 mutation and its roles in leukemogenesis revealed by a knock-in mouse model

Authors: Yueh-Chwen Hsu, Yu-Chiao Chiu, Chien-Chin Lin, Yuan-Yeh Kuo, Hsin-An Hou, Yi-Shiuan Tzeng, Chein-Jun Kao, Po-Han Chuang, Mei-Hsuan Tseng, Tzu-Hung Hsiao, Wen-Chien Chou, Hwei-Fang Tien

Source: Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-15 (2017)

Subject Terms: Asxl1, MN1, Hematopoietic stem cell, Engraftment, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13045-017-0508-x; https://doaj.org/toc/1756-8722

Access URL: https://doaj.org/article/e1bcb35b80b140e5ac3ca19ec376ebd2

Concomitant WT1 mutations predict poor prognosis in acute myeloid leukemia patients with double mutant CEBPA

Authors: Feng-Ming Tien, Hsin-An Hou, Jih-Luh Tang, Yuan-Yeh Kuo, Chien-Yuan Chen, Cheng-Hong Tsai, Ming Yao, Chien-Ting Lin, Chi-Cheng Li, Shang-Yi Huang, Bor-Sheng Ko, Szu-Chun Hsu, Shang-Ju Wu, Jia-Hau Liu, Sheng Chieh Chou, Woei Tsay, Mei-Hsuan Tseng, Ming-Chih Liu, Chia-Wen Liu, Liang-In Lin, Wen-Chien Chou, Hwei-Fang Tien

Source: Haematologica, Vol 103, Iss 11 (2018)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/8675; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/b5617c9e41f041c086ae44b00c80a901

Distinct molecular genetics of chronic lymphocytic leukemia in Taiwan: clinical and pathogenetic implications

Authors: Shang-Ju Wu, Chien-Ting Lin, Andreas Agathangelidis, Liang-In Lin, Yuan-Yeh Kuo, Hwei-Fang Tien, Paolo Ghia

Source: Haematologica, Vol 102, Iss 6 (2017)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/8099; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/2213a7f19788439f9e43da483e2574f8

Higher HOPX expression is associated with distinct clinical and biological features and predicts poor prognosis in de novo acute myeloid leukemia

Authors: Chien-Chin Lin, Yueh-Chwen Hsu, Yi-Hung Li, Yuan-Yeh Kuo, Hsin-An Hou, Keng-Hsueh Lan, Tsung-Chih Chen, Yi-Shiuan Tzeng, Yi-Yi Kuo, Chein-Jun Kao, Po-Han Chuang, Mei-Hsuan Tseng, Yu-Chiao Chiu, Wen-Chien Chou, Hwei-Fang Tien

Source: Haematologica, Vol 102, Iss 6 (2017)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/8095; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/a7f7507adb43418086bba3823755de28

Mutation and Lineage Analysis of DNMT3A in BCR-ABL1-negative Chronic Myeloproliferative Neoplasms

Authors: Huan-Chau Lin, Shu-Ching Wang, Caleb Gon-Shen Chen, Ming-Chih Chang, Wei-Ting Wang, Nai-Wen Su, Hung-I Cheng, Johnson Lin, Yi-Fang Chang, Ruey-Kuen Hsieh, Chien-Chung Chang, Yuchi Hwang, Ken-Hong Lim, Yuan-Yeh Kuo

Source: International Journal of Gerontology, Vol 7, Iss 3, Pp 186-188 (2013)

Subject Terms: DNMT3A, mutation, myeloproliferative neoplasm, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1873959813000069; https://doaj.org/toc/1873-9598

Access URL: https://doaj.org/article/8da35d0012b24a9892ca26cdea777184

Clinical and prognostic implications of Roundabout 4 (robo4) in adult patients with acute myeloid leukemia.

Authors: Yin-Kai Chen, Hsin-An Hou, Jih-Luh Tang, Jie-Yang Jhuang, Yan-Jun Lai, Ming-Cheng Lee, Yuan-Yeh Kuo, Wen-Chien Chou, Chieh-Yu Liu, Chung-Wu Lin, Shih-Sung Chuang, Chien-Yuan Chen, Mei-Hsuan Tseng, Chi-Fei Huang, Ying-Chieh Chiang, Fen-Yu Lee, Ming-Chih Liu, Chia-Wen Liu, Ming Yao, Shang-Yi Huang, Bor-Sheng Ko, Szu-Chun Hsu, Shang-Ju Wu, Woei Tsay, Yao-Chang Chen, Hwei-Fang Tien

Source: PLoS ONE, Vol 10, Iss 3, p e0119831 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4368775?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/fc4bd59247cf40128068a13a9557cf65

The N-terminal CEBPA mutant in acute myeloid leukemia impairs CXCR4 expression

Authors: Yuan-Yeh Kuo, Hsin-An Hou, Yin-Kai Chen, Li-Yu Li, Po-Hsuen Chen, Mei-Hsuan Tseng, Chi-Fei Huang, Fen-Yu Lee, Ming-Chih Liu, Chia-Wen Liu, Wen-Chien Chou, Chieh-Yu Liu, Jih-Luh Tang, Ming Yao, Hwei-Fang Tien

Source: Haematologica, Vol 99, Iss 12 (2014)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/7220; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/cb50fa52893742bbbfbd0daba01d4503

The clinical implication of SRSF2 mutation in patients with myelodysplastic syndrome and its stability during disease evolution.

Authors: Shang-Ju Wu¹, Yuan-Yeh Kuo², Hsin-An Hou¹, Li-Yu Li², Mei-Hsuan Tseng¹, Chi-Fei Huang¹, Fen-Yu Lee³, Ming-Chih Liu³, Chia-Wen Liu³, Chien-Ting Lin¹, Chien-Yuan Chen¹, Wen-Chien Chou^1,4, Ming Yao¹, Shang-Yi Huang¹, Bor-Sheng Ko¹, Jih-Luh Tang¹, Woei Tsay¹, Hwei-Fang Tien¹ d90442001@ntu.edu.tw

Source: Blood. 10/11/2012, Vol. 120 Issue 15, p3106-3111. 6p.

Subject Terms: *MEDICAL genetics, *CLINICAL medicine, *MYELODYSPLASTIC syndromes, *SOMATIC mutation, *RNA splicing, *DISEASE progression, *PATIENTS

DNMT3A mutations in acute myeloid leukemia: stability during disease evolution and clinical implications.

Authors: Hsin-An Hou^1,2, Yuan-Yeh Kuo³, Chieh-Yu Liu⁴, Wen-Chien Chou^1,5, Ming Cheng Lee¹, Chien-Yuan Chen¹, Liang-In Lin⁶, Mei-Hsuan Tseng¹, Chi-Fei Huang¹, Ying-Chieh Chiang¹, Fen-Yu Lee⁷, Ming-Chih Liu⁷, Chia-Wen Liu⁷, Jih-Luh Tang¹, Ming Yao¹, Shang-Yi Huang¹, Bor-Sheng Ko¹, Szu-Chun Hsu⁵, Shang-Ju Wu¹, Woei Tsay¹

Source: Blood. 1/12/2012, Vol. 119 Issue 2, p559-568. 10p.

Subject Terms: *ACUTE myeloid leukemia, *CYTOGENETICS, *GENETIC mutation, *MULTIVARIATE analysis, *LEUKOCYTES, *BLOOD platelets

Control of dTTP pool size by anaphase promoting complex/cyclosome is essential for the maintenance of genetic stability.

Authors: Po-Yuan Ke¹, Yuan-Yeh Kuo¹, Chuan-Mei Hu¹, Zee-Fen Chang¹ zfchang@ha.mc.ntu.edu.tw

Source: Genes & Development. 8/15/2005, Vol. 19 Issue 16, p1920-1933. 14p. 5 Diagrams, 6 Graphs.

Subject Terms: *PROTEOLYSIS, *CELL cycle, *THYMIDINE, *MITOSIS, *GROWTH factors

GATA-1 and Gfi-1B Interplay To Regulate Bcl-xL Transcription.

Authors: Yuan-Yeh Kuo¹, Zee-Fen Chang¹ ZFCHANG@ha.mc.ntu.edu.tw

Source: Molecular & Cellular Biology. Jun2007, Vol. 27 Issue 12, p6-6. 1p.

Subject Terms: *ERYTHROPOIESIS, *CELLS, *CHROMATIN, *THERAPEUTICS, *IMATINIB, *DRUG therapy, *APOPTOSIS