Induction of ER Stress by an AAV5 BDD FVIII Construct Is Dependent on the Strength of the Hepatic-Specific Promoter

Authors: Fong, Sylvia, Handyside, Britta, Sihn, Choong-Ryoul, Liu, Su, Zhang, Lening, Xie, Lin, Murphy, Ryan, Galicia, Nicole, Yates, Bridget, Minto, Wesley C., Vitelli, Catherine, Harmon, Danielle, Ru, Yuanbin, Yu, Guoying Karen, Escher, Claudia, Vowinckel, Jakob, Woloszynek, Jill, Akeefe, Hassib, Mahimkar, Rajeev, Bullens, Sherry, Bunting, Stuart

Source: In Molecular Therapy - Methods & Clinical Development 11 September 2020 18:620-630

Assessment of predicted enzymatic activity of α‐N‐acetylglucosaminidase variants of unknown significance for CAGI 2016

Authors: Clark, Wyatt T., Kasak, Laura, Bakolitsa, Constantina, Hu, Zhiqiang, Andreoletti, Gaia, Babbi, Giulia, Bromberg, Yana, Casadio, Rita, Dunbrack, Roland, Folkman, Lukas, Ford, Colby T., Jones, David, Katsonis, Panagiotis, Kundu, Kunal, Lichtarge, Olivier, Martelli, Pier L., Mooney, Sean D., Nodzak, Conor, Pal, Lipika R., Radivojac, Predrag, Savojardo, Castrense, Shi, Xinghua, Zhou, Yaoqi, Uppal, Aneeta, Xu, Qifang, Yin, Yizhou, Pejaver, Vikas, Wang, Meng, Wei, Liping, Moult, John, Yu, Guoying Karen, Brenner, Steven E., LeBowitz, Jonathan H.

Source: Human mutation. 40(9):1519-1529

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100088915299.0x000001&indx=1&recIds=ETOCvdc_100088915299.0x000001

Quantitative Assessment of Neuroinflammation, Myelinogenesis, Demyelination, and Nerve Fiber Regeneration in Immunostained Sciatic Nerves From Twitcher Mice With a Tissue Image Analysis Platform.

Authors: Wilson, Irene, Vitelli, Cathy, Yu, Guoying Karen, Pacheco, Glenn, Vincelette, Jon, Bunting, Stuart, Sisó, Sílvia

Source: Toxicologic Pathology; Jun2021, Vol. 49 Issue 4, p950-962, 13p

Subject Terms: NERVE fibers, MYELINATION, SCIATIC nerve, IMAGE analysis, TISSUE analysis, OLIGODENDROGLIA, SCHWANN cells

Identifying therapeutic drug targets using bidirectional effect genes.

Authors: Estrada, Karol, Froelich, Steven, Wuster, Arthur, Bauer, Christopher R., Sterling, Teague, Clark, Wyatt T., Ru, Yuanbin, Trinidad, Marena, Nguyen, Hong Phuc, Luu, Amanda R., Wendt, Daniel J., Yogalingam, Gouri, Yu, Guoying Karen, LeBowitz, Jonathan H., Cardon, Lon R.

Source: Nature Communications; 4/13/2021, Vol. 12 Issue 1, p1-11, 11p

Subject Terms: DRUG utilization, SHORT stature, PHENOTYPES, GENE targeting

This result is not displayed to guests.
Login for full access.