Hint from an Enzymatic Reaction: Superoxide Dismutase Models Efficiently Suppress Colorectal Cancer Cell Proliferation

Authors: Lim, Hanae, Oh, Chaeun, Park, Myong-Suk, Park, Hyung-Bin, Ahn, Chaewon, Bae, Woo Kyun, Yoo, Kyung Hyun, Hong, Seungwoo

Source: Journal of the American Chemical Society. 145(29):16058-16068

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN633261177&indx=1&recIds=ETOCRN633261177

MicroRNA-dependent inhibition of WEE1 controls cancer stem-like characteristics and malignant behavior in ovarian cancer

Authors: Cho, Jin Gu, Kim, Sung-wook, Lee, Aram, Jeong, Ha-neul, Yun, Eunsik, Choi, Jihea, Jeong, Su Jin, Chang, Woochul, Oh, Sumin, Yoo, Kyung Hyun, Lee, Jung Bok, Yoon, Sukjoon, Lee, Myeong-Sok, Park, Jong Hoon, Jung, Min Hyung, Kim, So-Woon, Kim, Ki Hyung, Suh, Dong Soo, Choi, Kyung Un, Choi, Jungmin, Kim, Jongmin, Kwon, Byung Su

Source: In Molecular Therapy - Nucleic Acids 13 September 2022 29:803-822

Integrative transcriptomic and genomic analyses unveil the IFI16 variants and expression as MASLD progression markers.

Authors: Kim, Doyoon, Shah, Masaud, Kim, Jang Hyun, Kim, JungMo, Baek, Yang-Hyun, Jeong, Jin-Sook, Han, Sang-Young, Lee, Yong Sun, Park, Gaeul, Cho, Jin-Han, Roh, Young-Hoon, Lee, Sung-Wook, Choi, Gi-Bok, Park, Jong Hoon, Yoo, Kyung Hyun, Seong, Rho Hyun, Lee, Yeon-Su, Woo, Hyun Goo

Source: Hepatology (02709139); Mar2025, Vol. 81 Issue 3, p962-975, 14p

Bioinspired nonheme iron complex that triggers mitochondrial apoptotic signalling pathway specifically for colorectal cancer cellsElectronic supplementary information (ESI) available. CCDC 1999286–1999288. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/d1sc05094j

Authors: Lee, Yool, Oh, Chaeun, Kim, Jin, Park, Myong-Suk, Bae, Woo Kyun, Yoo, Kyung Hyun, Hong, Seungwoo

Source: Chemical science. 13(3):737-747

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139045322.0x000001&indx=1&recIds=ETOCvdc_100139045322.0x000001

TAZ/Wnt-β-catenin/c-MYC axis regulates cystogenesis in polycystic kidney disease

Authors: Lee, Eun Ji, Seo, Eunjeong, Kim, Jin Won, Nam, Sun Ah, Lee, Jong Young, Jun, Jaehee, Oh, Sumin, Park, Minah, Jho, Eek-hoon, Yoo, Kyung Hyun, Park, Jong Hoon, Kim, Yong Kyun

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Nov . 117(46), 29001-29012.

Access URL: https://www.jstor.org/stable/26971025

Transcriptome analysis upon potassium usnate exposure reveals ATF3-induced apoptosis in human gastric and colon cancer cells

Authors: Yoo, Kyung Hyun, Kim, Dae-Hwan, Oh, Sumin, Park, Myong-Suk, Kim, Hangun, Ha, Hyung-Ho, Cho, Sang-Hee, Chung, Ik-Joo, Bae, Woo Kyun

Source: In Phytomedicine October 2021 91

VIM-AS1, which is regulated by CpG methylation, cooperates with IGF2BP1 to inhibit tumor aggressiveness via EPHA3 degradation in hepatocellular carcinoma.

Authors: Han, Su-hyang, Ko, Je Yeong, Jung, Sungju, Oh, Sumin, Kim, Do Yeon, Kang, Eunseo, Kim, Myung Sup, Chun, Kyung-Hee, Yoo, Kyung Hyun, Park, Jong Hoon

Source: Experimental & Molecular Medicine EMM; Dec2024, Vol. 56 Issue 12, p2617-2630, 14p

NRXN1 as a Prognostic Biomarker: Linking Copy Number Variation to EMT and Survival in Colon Cancer.

Authors: Bang, Hyun Jin, Shim, Hyun-Jeong, Park, Mi-Ra, Yoon, Sumin, Yoo, Kyung Hyun, Kim, Young-Kook, Lee, Hyunju, Nam, Jeong-Seok, Hwang, Jun-Eul, Bae, Woo-Kyun, Chung, Ik-Joo, Sun, Eun-Gene, Cho, Sang-Hee

Source: International Journal of Molecular Sciences; Nov2024, Vol. 25 Issue 21, p11423, 15p

Subject Terms: COLON cancer, GENE expression, TUMOR markers, WESTERN immunoblotting, COLORECTAL cancer

Autophagy induction promotes renal cyst growth in polycystic kidney disease

Authors: Lee, Eun Ji, Ko, Je Yeong, Oh, Sumin, Jun, Jaehee, Mun, Hyowon, Lim, Chae Ji, Seo, Seungwoon, Ko, Hyuk Wan, Kim, Hyunho, Oh, Yun Kyu, Ahn, Curie, Kang, Minyong, Kim, Min Jung, Yoo, Kyung Hyun, Oh, Goo Taeg, Park, Jong Hoon

Source: In EBioMedicine October 2020 60

Galectin 3‐binding protein (LGALS3BP) depletion attenuates hepatic fibrosis by reducing transforming growth factor‐β1 (TGF‐β1) availability and inhibits hepatocarcinogenesis.

Authors: Kim, Dae‐Hwan, Sung, Minjeong, Park, Myong‐Suk, Sun, Eun‐Gene, Yoon, Sumin, Yoo, Kyung Hyun, Radhakrishnan, Kamalakannan, Jung, Sung Yun, Bae, Woo‐Kyun, Cho, Sang‐Hee, Chung, Ik‐Joo

Source: Cancer Communications; Oct2024, Vol. 44 Issue 10, p1106-1129, 24p

Silent mating‐type information regulation 2 homolog 1 overexpression is an important strategy for the survival of adapted suspension tumor cells

Authors: Park, Ji Young, Han, Sora, Ka, Hye In, Joo, Hyun Jeong, Soh, Su Jung, Yoo, Kyung Hyun, Yang, Young

Source: Cancer science. 110(9):2773-2782

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100087646941.0x000001&indx=1&recIds=ETOCvdc_100087646941.0x000001

Impact of miR‐192 and miR‐194 on cyst enlargement through EMT in autosomal dominant polycystic kidney disease

Authors: Kim, Do Yeon, Woo, Yu Mi, Lee, Sunyoung, Oh, Sumin, Shin, Yubin, Shin, Jeong-Oh, Park, Eun Young, Ko, Je Yeong, Lee, Eun Ji, Bok, Jinwoong, Yoo, Kyung Hyun, Park, Jong Hoon

Source: FASEB journal. 33(2):2870-2884

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103608673.0x000001&indx=1&recIds=ETOCvdc_100103608673.0x000001

Hypomethylation of ATP1A1 Is Associated with Poor Prognosis and Cancer Progression in Triple-Negative Breast Cancer.

Authors: Kim, Yesol, Ko, Je Yeong, Kong, Hyun Kyung, Lee, Minyoung, Chung, Woosung, Lim, Sera, Son, Dasom, Oh, Sumin, Park, Jee Won, Kim, Do Yeon, Lee, Minju, Han, Wonshik, Park, Woong-Yang, Yoo, Kyung Hyun, Park, Jong Hoon

Source: Cancers; May2024, Vol. 16 Issue 9, p1666, 18p

Subject Terms: BREAST cancer prognosis, CANCER invasiveness, BREAST tumors, TUMOR markers, DNA methylation, ADENOSINE triphosphatase, CELL lines, GENE expression profiling, DISEASE progression

Functional Enhancers As Master Regulators of Tissue-Specific Gene Regulation and Cancer Development

Authors: Ko, Je Yeong, Oh, Sumin, Yoo, Kyung Hyun ^*

Source: In Molecules and Cells March 2017 40(3):169-177

STAT5-Driven Enhancers Tightly Control Temporal Expression of Mammary-Specific Genes

Authors: Shin, Ha Youn, Hennighausen, Lothar, Yoo, Kyung Hyun

Source: Journal of mammary gland biology and neoplasia. 24(1):61-71

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127565465.0x000001&indx=1&recIds=ETOCvdc_100127565465.0x000001

Dissecting Tissue-Specific Super-Enhancers by Integrating Genome-Wide Analyses and CRISPR/Cas9 Genome Editing

Authors: Yoo, Kyung Hyun, Hennighausen, Lothar, Shin, Ha Youn

Source: Journal of mammary gland biology and neoplasia. 24(1):47-59

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127565412.0x000001&indx=1&recIds=ETOCvdc_100127565412.0x000001

C1q/TNF-α–Related Protein 1 (CTRP1) Maintains Blood Pressure Under Dehydration Conditions

Authors: Han, Sora, Jeong, Ae Lee, Lee, Sunyi, Park, Jeong Su, Buyanravjikh, Sumiyasuren, Kang, Wonku, Choi, Seungmok, Park, Changmin, Han, Jin, Son, Woo-Chan, Yoo, Kyung Hyun, Cheong, Jae Hoon, Oh, Goo Taeg, Lee, Won-Young, Kim, Jongwan, Suh, Suk Hyo, Lee, Sang-Hak, Lim, Jong-Seok, Lee, Myeong-Sok, Yang, Young

Source: Circulation research. 123(5):e5-e19

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100066028226.0x000001&indx=1&recIds=ETOCvdc_100066028226.0x000001

Targeting the Epigenome as a Novel Therapeutic Approach for Breast Cancer

Authors: Oh, Sumin, Ko, Je Yeong, Oh, Chaeun, Yoo, Kyung Hyun

Source: Advances in experimental medicine and biology. 1026:287-314

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN614804439&indx=1&recIds=ETOCRN614804439

The T47D cell line is an ideal experimental model to elucidate the progesterone-specific effects of a luminal A subtype of breast cancer

Authors: Yu, Sungryul, Kim, Taemook, Yoo, Kyung Hyun, Kang, Keunsoo

Source: Biochemical and biophysical research communications. 486(3):752-758

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100047249252.0x000001&indx=1&recIds=ETOCvdc_100047249252.0x000001

The STAT5-regulated miR-193b locus restrains mammary stem and progenitor cell activity and alveolar differentiation

Authors: Yoo, Kyung Hyun, Kang, Keunsoo, Feuermann, Yonatan, Jang, Seung Jin, Robinson, Gertraud W., Hennighausen, Lothar

Source: In Developmental Biology 15 November 2014 395(2):245-254