Comparative effectiveness of subcutaneous sarilumab 200 mg biweekly, subcutaneous Tocilizumab 162 mg biweekly, and intravenous Tocilizumab 8 mg/kg every 4 weeks in patients with rheumatoid arthritis: a prospective cohort study

Authors: Akira Onishi, Masao Tanaka, Takayuki Fujii, Koichi Murata, Kosaku Murakami, Motomu Hashimoto, Ryu Watanabe, Yuji Nozaki, Chisato Ashida, Wataru Yamamoto, Hirotaka Yamada, Sho Sendo, Kosuke Ebina, Hidehiko Makino, Yonsu Son, Yumiko Wada, Kenichiro Hata, Shuichi Matsuda, Akio Morinobu

Source: Arthritis Research & Therapy, Vol 27, Iss 1, Pp 1-11 (2025)

Subject Terms: Rheumatoid arthritis, Antirheumatic agents, Interleukin-6 inhibitors, Tocilizumab, Sarilumab, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/fc8310747e0347119acb51116c294e72

Drug retention of biologics and Janus kinase inhibitors in patients with rheumatoid arthritis: the ANSWER cohort study

Authors: Motomu Hashimoto, Wataru Yamamoto, Atsushi Kumanogoh, Yuichi Maeda, Yasutaka Okita, Ken Nakata, Shinya Hayashi, Masaki Katayama, Tadashi Okano, Takayuki Fujii, Seiji Okada, Kosuke Ebina, Yuki Etani, Makoto Hirao, Koichi Murata, Ryota Hara, Koji Nagai, Yuri Hiramatsu, Yonsu Son, Hideki Amuro, Takaichi Okano, Yo Ueda, Shotaro Tachibana

Source: RMD Open, Vol 9, Iss 3 (2023)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://rmdopen.bmj.com/content/9/3/e003160.full; https://doaj.org/toc/2056-5933

Access URL: https://doaj.org/article/c7789ed324f64b73b06d2a49de139a14

Panniculitis in dermatomyositis: Two cases with antitranscriptional intermediary factor‐1 antibody as myositis‐specific antibody and review of the literature

Authors: Kaori Takezawa, Ikuko Ueda‐Hayakawa, Akihiro Tanaka, Yonsu Son, Fumikazu Yamazaki, Naotomo Kambe, Hiroyuki Okamoto, Manabu Fujimoto

Source: Journal of Cutaneous Immunology and Allergy, Vol 5, Iss 3, Pp 88-93 (2022)

Subject Terms: antitranscriptional intermediary factor‐1 antibody, clinical feature, dermatomyositis, myositis‐specific autoantibody, panniculitis, Dermatology, RL1-803, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2574-4593

Access URL: https://doaj.org/article/29c93efeae694f749a12ebf738d380e1

Factors affecting drug retention of Janus kinase inhibitors in patients with rheumatoid arthritis: the ANSWER cohort study

Authors: Kosuke Ebina, Toru Hirano, Yuichi Maeda, Wataru Yamamoto, Motomu Hashimoto, Koichi Murata, Akira Onishi, Sadao Jinno, Ryota Hara, Yonsu Son, Hideki Amuro, Tohru Takeuchi, Ayaka Yoshikawa, Masaki Katayama, Keiichi Yamamoto, Yasutaka Okita, Makoto Hirao, Yuki Etani, Atsushi Kumanogoh, Seiji Okada, Ken Nakata

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/4f5b37cb670c499a922ca1bc68f13735

Comparison of the drug retention and reasons for discontinuation of tumor necrosis factor inhibitors and interleukin-6 inhibitors in Japanese patients with elderly-onset rheumatoid arthritis—the ANSWER cohort study

Authors: Sadao Jinno, Akira Onishi, Maureen Dubreuil, Motomu Hashimoto, Wataru Yamamoto, Koichi Murata, Tohru Takeuchi, Takuya Kotani, Yuichi Maeda, Kosuke Ebina, Yonsu Son, Hideki Amuro, Ryota Hara, Masaki Katayama, Jun Saegusa

Source: Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-9 (2021)

Subject Terms: ANSWER cohort, Biological disease-modifying antirheumatic drugs, Drug retention, Elderly onset rheumatoid arthritis, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/d2017bdb0d4045efb9549d25234a243b

Mycophenolic acid, the active form of mycophenolate mofetil, interferes with IRF7 nuclear translocation and type I IFN production by plasmacytoid dendritic cells

Authors: Minoru Shigesaka, Tomoki Ito, Muneo Inaba, Kai Imai, Hideki Yamanaka, Yoshiko Azuma, Akihiro Tanaka, Hideki Amuro, Tohru Nishizawa, Yonsu Son, Atsushi Satake, Yoshio Ozaki, Shosaku Nomura

Source: Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-11 (2020)

Subject Terms: SLE, Plasmacytoid DCs, Myeloid DCs, Type I IFN, MPA, IRF7, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13075-020-02356-z; https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/e81bcc18f79f45499484f4c1e8f8cccc

Drug retention of 7 biologics and tofacitinib in biologics-naïve and biologics-switched patients with rheumatoid arthritis: the ANSWER cohort study

Authors: Kosuke Ebina, Toru Hirano, Yuichi Maeda, Wataru Yamamoto, Motomu Hashimoto, Koichi Murata, Tohru Takeuchi, Hideyuki Shiba, Yonsu Son, Hideki Amuro, Akira Onishi, Kengo Akashi, Ryota Hara, Masaki Katayama, Keiichi Yamamoto, Atsushi Kumanogoh, Makoto Hirao

Source: Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-11 (2020)

Subject Terms: ANSWER cohort, Biological disease-modifying antirheumatic drugs, Drug retention, Rheumatoid arthritis, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13075-020-02232-w; https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/4669e0ad46c94ef0981d1d8a12dd9861

The Correlation between the Vascular Calcification Score of the Coronary Artery and the Abdominal Aorta in Patients with Psoriasis

Authors: Trang Nguyen-Mai Huynh, Fumikazu Yamazaki, Izumi Kishimoto, Akihiro Tanaka, Yonsu Son, Yoshio Ozaki, Kazuya Takehana, Hideaki Tanizaki

Source: Diagnostics, Vol 13, Iss 2, p 274 (2023)

Subject Terms: calcification, coronary artery, abdominal aorta, psoriasis, risk factors, velocity, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/2075-4418/13/2/274; https://doaj.org/toc/2075-4418

Access URL: https://doaj.org/article/574f478e4f5e490a80fa2a5d2374c4c3

Correction to: Drug tolerability and reasons for discontinuation of seven biologics in 4466 treatment courses of rheumatoid arthritis—the ANSWER cohort study

Authors: Kosuke Ebina, Motomu Hashimoto, Wataru Yamamoto, Toru Hirano, Ryota Hara, Masaki Katayama, Akira Onishi, Koji Nagai, Yonsu Son, Hideki Amuro, Keiichi Yamamoto, Yuichi Maeda, Koichi Murata, Sadao Jinno, Tohru Takeuchi, Makoto Hirao, Atsushi Kumanogoh, Hideki Yoshikawa

Source: Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-4 (2019)

Subject Terms: Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13075-019-1897-8; https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/a638623c16d5486fb66e1ce77e0ada0d

Drug tolerability and reasons for discontinuation of seven biologics in 4466 treatment courses of rheumatoid arthritis—the ANSWER cohort study

Authors: Kosuke Ebina, Motomu Hashimoto, Wataru Yamamoto, Toru Hirano, Ryota Hara, Masaki Katayama, Akira Onishi, Koji Nagai, Yonsu Son, Hideki Amuro, Keiichi Yamamoto, Yuichi Maeda, Koichi Murata, Sadao Jinno, Tohru Takeuchi, Makoto Hirao, Atsushi Kumanogoh, Hideki Yoshikawa

Source: Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-10 (2019)

Subject Terms: ANSWER cohort, Biological disease-modifying antirheumatic drugs, Discontinuation, Rheumatoid arthritis, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13075-019-1880-4; https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/8276c108654a42928fa6b40574c6e116

Factors associated with the achievement of biological disease-modifying antirheumatic drug-free remission in rheumatoid arthritis: the ANSWER cohort study

Authors: Motomu Hashimoto, Moritoshi Furu, Wararu Yamamoto, Takanori Fujimura, Ryota Hara, Masaki Katayama, Akira Ohnishi, Kengo Akashi, Shuzo Yoshida, Koji Nagai, Yonsu Son, Hideki Amuro, Toru Hirano, Kosuke Ebina, Ryuji Uozumi, Hiromu Ito, Masao Tanaka, Koichiro Ohmura, Takao Fujii, Tsuneyo Mimori

Source: Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-10 (2018)

Subject Terms: Rheumatoid arthritis, Biological disease-modifying antirheumatic drugs, Discontinuation, Tumor necrosis factor, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13075-018-1673-1; https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/4cd5e2f3433e4dbcad326af2ee7761ea

Drug tolerability and reasons for discontinuation of seven biologics in elderly patients with rheumatoid arthritis -The ANSWER cohort study.

Authors: Kosuke Ebina, Motomu Hashimoto, Wataru Yamamoto, Toru Hirano, Ryota Hara, Masaki Katayama, Akira Onishi, Koji Nagai, Yonsu Son, Hideki Amuro, Keiichi Yamamoto, Yuichi Maeda, Koichi Murata, Sadao Jinno, Tohru Takeuchi, Makoto Hirao, Atsushi Kumanogoh, Hideki Yoshikawa

Source: PLoS ONE, Vol 14, Iss 5, p e0216624 (2019)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/8c0d1d916a504071bbc6c6d78ba62932

Drug retention and discontinuation reasons between seven biologics in patients with rheumatoid arthritis -The ANSWER cohort study.

Authors: Kosuke Ebina, Motomu Hashimoto, Wataru Yamamoto, Akira Ohnishi, Daijiro Kabata, Toru Hirano, Ryota Hara, Masaki Katayama, Shuzo Yoshida, Koji Nagai, Yonsu Son, Hideki Amuro, Kengo Akashi, Takanori Fujimura, Makoto Hirao, Keiichi Yamamoto, Ayumi Shintani, Atsushi Kumanogoh, Hideki Yoshikawa

Source: PLoS ONE, Vol 13, Iss 3, p e0194130 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5854351?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/da74f67791e94618b8e588c6dd945d6e

Prognostic factors affecting respiratory-related death in patients with rheumatoid arthritis complicated by interstitial lung disease: An ANSWER cohort study.

Authors: Hidehiko Makino, Kotani, Takuya, Hata, Kenichiro, Nishioka, Daisuke, Yamamoto, Wataru, Yoshikawa, Ayaka, Wada, Yumiko, Hiramatsu, Yuri, Shiba, Hideyuki, Nagai, Koji, Katayama, Masaki, Yonsu Son, Amuro, Hideki, Onishi, Akira, Akashi, Kengo, Hara, Ryota, Hirano, Toru, Hashimotoj, Motomu, Takeuchia, Tohru

Source: Modern Rheumatology; Sep2023, Vol. 33 Issue 5, p928-935, 8p

Subject Terms: INTERSTITIAL lung diseases, RHEUMATOID arthritis, PROGNOSIS, COHORT analysis, DISEASE duration, PEPTIDES

Drug retention of biologics and Janus kinase inhibitors in patients with rheumatoid arthritis: the ANSWER cohort study.

Authors: Kosuke Ebina, Yuki Etani, Yuichi Maeda, Yasutaka Okita, Makoto Hirao, Wataru Yamamoto, Motomu Hashimoto, Koichi Murata, Ryota Hara, Koji Nagai, Yuri Hiramatsu, Yonsu Son, Hideki Amuro, Takayuki Fujii, Takaichi Okano, Yo Ueda, Masaki Katayama, Tadashi Okano, Shotaro Tachibana, Shinya Hayashi

Source: RMD Open; Aug2023, Vol. 9 Issue 3, p1-11, 11p

Anti-MDA-5 Antibody-positive Dermatomyositis after Allogeneic Bone Marrow Transplantation for Acute Transformation of Chronic Myelogenous Leukemia.

Authors: Mariko Futamura, Yoshio Ozaki, Hidehiko Makino, Saki Tsujimoto, Minoru Shigesaka, Akihiro Tanaka, Keiko Shimamoto, Yonsu Son, Tomoki Ito, Shosaku Nomura

Source: Internal Medicine; 2023, Vol. 62 Issue 7, p1081-1087, 7p

The real-world effectiveness of anti-RANKL antibody denosumab on the clinical fracture prevention in patients with rheumatoid arthritis: The ANSWER cohort study.

Authors: Koichi Murata, Ryuji Uozumi, Motomu Hashimoto, Kosuke Ebina, Kengo Akashi, Akira Onishi, Koji Nagai, Ayaka Yoshikawa, Masaki Katayama, Yonsu Son, Hideki Amuro, Ryota Hara, Wataru Yamamoto, Ryu Watanabe, Kosaku Murakami, Masao Tanaka, Hiromu Ito, Akio Morinobu, Shuichi Matsuda

Source: Modern Rheumatology; Jul2022, Vol. 32 Issue 4, p834-838, 5p

Subject Terms: RHEUMATOID arthritis, DENOSUMAB, COHORT analysis, IMMUNOGLOBULINS

Hydroxychloroquine for the treatment of lupus erythematosus with cutaneous involvement: clinical efficacy and serial analysis of anti-DNA antibody levels.

Authors: Ikuko UEDA-HAYAKAWA, Nhung Thi My LY, Chuyen Thi Hong NGUYEN, Tomoko MATSUDA, Fumikazu YAMAZAKI, Naotomo KAMBE, Yonsu SON, Hiroyuki OKAMOTO

Source: European Journal of Dermatology; Sep/Oct2019, Vol. 29 Issue 5, p557-559, 3p

Serum Interleukin 6 Before and After Therapy with Tocilizumab Is a Principal Biomarker in Patients with Rheumatoid Arthritis.

Authors: Keiko Shimamoto, Tomoki Ito, Yoshio Ozaki, Hideki Amuro, Akihiro Tanaka, Tohru Nishizawa, Yonsu Son, Muneo Inaba, Shosaku Nomura

Source: Journal of Rheumatology; Jul2013, Vol. 40 Issue 7, p1074-1081, 8p

Statins, Inhibitors of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase, Function as Inhibitors of Cellular and Molecular Components Involved in Type I Interferon Production.

Authors: Amuro, Hideki, Ito, Tomoki, Miyamoto, Rie, Sugimoto, Hiroyuki, Torii, Yoshitaro, Yonsu Son, Nakamichi, Naoto, Yamazaki, Chihiro, Hoshino, Katsuaki, Kaisho, Tsuneyasu, Ozaki, Yoshio, Inaba, Muneo, Amakawa, Ryuichi, Fukuhara, Shirou

Source: Arthritis & Rheumatism; Jul2010, Vol. 62 Issue 7, p2073-2085, 13p, 1 Diagram, 6 Graphs

Subject Terms: STATINS (Cardiovascular agents), INTERFERONS, DENDRITIC cells, TUMOR necrosis factors, LIGANDS (Biochemistry), AUTOIMMUNE disease treatment