Oxytocin improves maternal licking behavior deficits in autism-associated Shank3 mutant dogs

Authors: Wen Lyu, Yuan Li, Aiyu Yao, Qing-quan Tan, Rong Zhang, Jian-ping Zhao, Kun Guo, Yong-hui Jiang, Rui Tian, Yong Q. Zhang

Source: Translational Psychiatry, Vol 15, Iss 1, Pp 1-10 (2025)

Subject Terms: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://doaj.org/toc/2158-3188

Access URL: https://doaj.org/article/ed52001f739e4e9db7c774e58a72a154

Endothelial SHANK3 regulates tight junctions in the neonatal mouse blood-brain barrier through β-Catenin signaling

Authors: Yong-Eun Kim, Minseong Kim, Sunwhi Kim, Raham Lee, Yusuke Ujihara, Esther Magdalena Marquez-Wilkins, Yong-Hui Jiang, Esther Yang, Hyun Kim, Changhoon Lee, Changwon Park, Il Hwan Kim

Source: Nature Communications, Vol 16, Iss 1, Pp 1-17 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/69688edb737b43f69e5f1ee2272b7945

Proximity analysis of native proteomes reveals phenotypic modifiers in a mouse model of autism and related neurodevelopmental conditions

Authors: Yudong Gao, Daichi Shonai, Matthew Trn, Jieqing Zhao, Erik J. Soderblom, S. Alexandra Garcia-Moreno, Charles A. Gersbach, William C. Wetsel, Geraldine Dawson, Dmitry Velmeshev, Yong-hui Jiang, Laura G. Sloofman, Joseph D. Buxbaum, Scott H. Soderling

Source: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/f993b5c92d79459eb326486abfab23a3

Transcriptome analysis identifies an ASD-Like phenotype in oligodendrocytes and microglia from C58/J amygdala that is dependent on sex and sociability

Authors: George D. Dalton, Stephen K. Siecinski, Viktoriya D. Nikolova, Gary P. Cofer, Kathryn J. Hornburg, Yi Qi, G. Allan Johnson, Yong-Hui Jiang, Sheryl S. Moy, Simon G. Gregory

Source: Behavioral and Brain Functions, Vol 20, Iss 1, Pp 1-23 (2024)

Subject Terms: Autism, Oligodendrocyte, Microglia, Myelin, Oxytocin, Amygdala, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1744-9081

Access URL: https://doaj.org/article/3a0dc3d8da37446598bf596a2a78dc61

Impaired synaptic function and hyperexcitability of the pyramidal neurons in the prefrontal cortex of autism-associated Shank3 mutant dogs

Authors: Feipeng Zhu, Qi Shi, Yong-hui Jiang, Yong Q. Zhang, Hui Zhao

Source: Molecular Autism, Vol 15, Iss 1, Pp 1-14 (2024)

Subject Terms: Shank3, Autism spectrum disorder, Synaptic transmission, Excitability, Dog, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2040-2392

Access URL: https://doaj.org/article/c33e2697ba1d414aa5290ce5fc5ff14d

Patterns of Cytogenomic Findings from a Case Series of Recurrent Pregnancy Loss Provide Insight into the Extent of Genetic Defects Causing Miscarriages

Authors: Autumn DiAdamo, Hongyan Chai, Mei Ling Chong, Guilin Wang, Jiadi Wen, Yong-Hui Jiang, Peining Li

Source: Global Medical Genetics, Vol 11, Iss 01, Pp 123-131 (2024)

Subject Terms: recurrent pregnancy loss, products of conception, chromosomal abnormalities, pathogenic copy number variants, Genetics, QH426-470, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2699-9404

Access URL: https://doaj.org/article/b5a57dd33fbc45bcafbbfdc3162cd114

Transcriptional determinism and stochasticity contribute to the complexity of autism-associated SHANK family genes

Authors: Xiaona Lu, Pengyu Ni, Paola Suarez-Meade, Yu Ma, Emily Niemitz Forrest, Guilin Wang, Yi Wang, Alfredo Quiñones-Hinojosa, Mark Gerstein, Yong-hui Jiang

Source: Cell Reports, Vol 43, Iss 7, Pp 114376- (2024)

Subject Terms: CP: Neuroscience, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124724007046; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/fc95a257f22349b9bb5b87d26085c896

Identifying critical windows of air pollution exposure during preconception and gestational period on birthweight: a prospective cohort study

Authors: Jiawen Liao, Yi Zhang, Zhenchun Yang, Chenyu Qiu, Wu Chen, Junfeng Jim Zhang, Kiros Berhane, Zhipeng Bai, Bin Han, Jia Xu, Yong-hui Jiang, Frank Gilliland, Weili Yan, Guoying Huang, Zhanghua Chen

Source: Environmental Health, Vol 22, Iss 1, Pp 1-14 (2023)

Subject Terms: Air Pollutant, Small for gestational age, Large for gestational age, Preconception, Pregnancy, Birthweight, Industrial medicine. Industrial hygiene, RC963-969, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1476-069X

Access URL: https://doaj.org/article/758ee18f7365441492f70eb32d2e1e39

CHD8 mutations increase gliogenesis to enlarge brain size in the nonhuman primate

Authors: Bang Li, Hui Zhao, Zhuchi Tu, Weili Yang, Rui Han, Lu Wang, Xiaopeng Luo, Mingtian Pan, Xiusheng Chen, Jiawei Zhang, Huijuan Xu, Xiangyu Guo, Sen Yan, Peng Yin, Zhiguang Zhao, Jianrong Liu, Yafeng Luo, Yuefeng Li, Zhengyi Yang, Baogui Zhang, Zhiqiang Tan, Hao Xu, Tianzi Jiang, Yong-hui Jiang, Shihua Li, Yong Q. Zhang, Xiao-Jiang Li

Source: Cell Discovery, Vol 9, Iss 1, Pp 1-23 (2023)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2056-5968

Access URL: https://doaj.org/article/f4a0a5dc3c484d7ab32f386567e0b825

P602: Genetic modifiers as a basis for phenotypic variability in mosaic trisomy 8

Authors: Zakia Abdelhamed, Daniel Dykas, Autumn DiAdamo, Jai-Di Wen, Hui Zhang, Michele Spencer-Manzon, Peining Li, Yong-Hui Jiang, Allen Bale

Source: Genetics in Medicine Open, Vol 2, Iss , Pp 101508- (2024)

Subject Terms: Genetics, QH426-470, Medicine

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S294977442400654X; https://doaj.org/toc/2949-7744

Access URL: https://doaj.org/article/b29eefdfda3a4640ad0e77343e2d061d

Estimation on risk of spontaneous abortions by genomic disorders from a meta‐analysis of microarray results on large case series of pregnancy losses

Authors: Gang Peng, Qinghua Zhou, Hongyan Chai, Jiadi Wen, Hongyu Zhao, Hugh S. Taylor, Yong‐Hui Jiang, Peining Li

Source: Molecular Genetics & Genomic Medicine, Vol 11, Iss 8, Pp n/a-n/a (2023)

Subject Terms: chromosome microarray analysis (CMA), genomic disorders, pathogenic copy number variants (pCNVs), pregnancy loss (PL), products of conception (POC), spontaneous abortion (SAB), Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/2324-9269

Access URL: https://doaj.org/article/b6114eb278a54495b6af068716582854

Vitamin C epigenetically controls osteogenesis and bone mineralization

Authors: Roman Thaler, Farzaneh Khani, Ines Sturmlechner, Sharareh S. Dehghani, Janet M. Denbeigh, Xianhu Zhou, Oksana Pichurin, Amel Dudakovic, Sofia S. Jerez, Jian Zhong, Jeong-Heon Lee, Ramesh Natarajan, Ivo Kalajzic, Yong-hui Jiang, David R. Deyle, Eleftherios P. Paschalis, Barbara M. Misof, Tamas Ordog, Andre J. van Wijnen

Source: Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/03ddd7fcf25c4309b04599c7af2fbd14

SHANK3 in vagal sensory neurons regulates body temperature, systemic inflammation, and sepsis

Authors: Linlin Zhang, Sangsu Bang, Qianru He, Megumi Matsuda, Xin Luo, Yong-Hui Jiang, Ru-Rong Ji

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: autism, nodose ganglion, sepsis, TRPM2, TRPV1, vagus nerve, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1124356/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/5609d08e859f4a66879311570b8b5490

P641: Whole-exome sequencing on product of conception: A cohort study to evaluate clinical utility and genetic etiology for pregnancy loss

Authors: Chen Zhao, Hongyan Chai, Hui Zhang, Yong-hui Jiang, Peining Li, Allen Bale

Source: Genetics in Medicine Open, Vol 1, Iss 1, Pp 100697- (2023)

Subject Terms: Genetics, QH426-470, Medicine

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2949774423006970; https://doaj.org/toc/2949-7744

Access URL: https://doaj.org/article/dc32c9c017a14512bc28091566f66ab6

TET1-mediated DNA hydroxymethylation regulates adult remyelination in mice

Authors: Sarah Moyon, Rebecca Frawley, Damien Marechal, Dennis Huang, Katy L. H. Marshall-Phelps, Linde Kegel, Sunniva M. K. Bøstrand, Boguslawa Sadowski, Yong-Hui Jiang, David A. Lyons, Wiebke Möbius, Patrizia Casaccia

Source: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/0cc9b5962f0a40eabbf4462ab04b7567

BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology

Authors: Liansheng Zhang, Yun Qian, Jie Li, Xuan Zhou, He Xu, Jie Yan, Jialing Xiang, Xiang Yuan, Beicheng Sun, Sangram S. Sisodia, Yong-Hui Jiang, Xiaohua Cao, Naihe Jing, Anning Lin

Source: iScience, Vol 24, Iss 9, Pp 102942- (2021)

Subject Terms: Molecular biology, Neuroscience, Molecular neuroscience, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S258900422100910X; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/4f8639ed15974668b2c7dbbdfeb33c90

Autism-associated CHD8 deficiency impairs axon development and migration of cortical neurons

Authors: Qiong Xu, Yuan-yuan Liu, Xiaoming Wang, Guo-he Tan, Hui-ping Li, Samuel W. Hulbert, Chun-yang Li, Chun-chun Hu, Zhi-qi Xiong, Xiu Xu, Yong-hui Jiang

Source: Molecular Autism, Vol 9, Iss 1, Pp 1-17 (2018)

Subject Terms: CHD8, Autism spectrum disorder (ASD), Chromatin remodeling, Neurite growth, Neurodevelopment, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13229-018-0244-2; https://doaj.org/toc/2040-2392

Access URL: https://doaj.org/article/f5e82f90f69d4bb7af33c882d69be995

Role of PUF60 gene in Verheij syndrome: a case report of the first Chinese Han patient with a de novo pathogenic variant and review of the literature

Authors: Qiong Xu, Chun-yang Li, Yi Wang, Hui-ping Li, Bing-bing Wu, Yong-hui Jiang, Xiu Xu

Source: BMC Medical Genomics, Vol 11, Iss 1, Pp 1-5 (2018)

Subject Terms: PUF60, Verheij syndrome, Intellectual disability, Chinese Han patient, Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12920-018-0421-3; https://doaj.org/toc/1755-8794

Access URL: https://doaj.org/article/9d910014222e4651af6a5c3dafbef518

Characteristics of undiagnosed diseases network applicants: implications for referring providers

Authors: Nicole M. Walley, Loren D. M. Pena, Stephen R. Hooper, Heidi Cope, Yong-Hui Jiang, Allyn McConkie-Rosell, Camilla Sanders, Kelly Schoch, Rebecca C. Spillmann, Kimberly Strong, Alexa T. McCray, Paul Mazur, Cecilia Esteves, Kimberly LeBlanc, Undiagnosed Diseases Network, Anastasia L. Wise, Vandana Shashi

Source: BMC Health Services Research, Vol 18, Iss 1, Pp 1-8 (2018)

Subject Terms: Medically unexplained symptoms, Medically unexplained physical symptoms, Undiagnosed diseases, Genomics, Health policy, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12913-018-3458-2; https://doaj.org/toc/1472-6963

Access URL: https://doaj.org/article/41a86d65a9524c2abee5f89c183cb163

CRISPR/Cas9-induced shank3b mutant zebrafish display autism-like behaviors

Authors: Chun-xue Liu, Chun-yang Li, Chun-chun Hu, Yi Wang, Jia Lin, Yong-hui Jiang, Qiang Li, Xiu Xu

Source: Molecular Autism, Vol 9, Iss 1, Pp 1-13 (2018)

Subject Terms: shank3, CRISPR/Cas9, Zebrafish, ASD, Social behavior, Animal model, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13229-018-0204-x; https://doaj.org/toc/2040-2392

Access URL: https://doaj.org/article/76d8d4748b244b049725f5167964fe4a