All-in-one bimodal DNA and RNA next-generation sequencing panel for integrative diagnosis of glioma

Authors: Higa, Nayuta, Akahane, Toshiaki, Kirishima, Mari, Yonezawa, Hajime, Makino, Ryutaro, Uchida, Hiroyuki, Yokoyama, Seiya, Takajo, Tomoko, Otsuji, Ryosuke, Fujioka, Yutaka, Sangatsuda, Yuhei, Kuga, Daisuke, Yamahata, Hitoshi, Hata, Nobuhiro, Horie, Nobutaka, Kurosaki, Masamichi, Yamamoto, Junkoh, Yoshimoto, Koji, Tanimoto, Akihide, Hanaya, Ryosuke

Source: In Pathology - Research and Practice November 2024 263

Prognosis prediction via histological evaluation of cellular heterogeneity in glioblastoma.

Authors: Kirishima, Mari¹ (AUTHOR), Yokoyama, Seiya¹ (AUTHOR), Akahane, Toshiaki^1,2 (AUTHOR), Higa, Nayuta³ (AUTHOR), Uchida, Hiroyuki³ (AUTHOR), Yonezawa, Hajime³ (AUTHOR), Matsuo, Kei¹ (AUTHOR), Yamamoto, Junkoh⁴ (AUTHOR), Yoshimoto, Koji⁵ (AUTHOR), Hanaya, Ryosuke³ (AUTHOR) hanaya@m2.kufm.kagoshima-u.ac.jp, Tanimoto, Akihide^1,2,6 (AUTHOR) akit09@m3.kufm.kagoshima-u.ac.jp

Source: Scientific Reports. 10/23/2024, Vol. 14 Issue 1, p1-11. 11p.

Subject Terms: *O6-Methylguanine-DNA Methyltransferase, *CELL analysis, *PROGNOSIS, *CELL anatomy, CENTRAL nervous system tumors

Distribution and favorable prognostic implication of genomic EGFR alterations in IDH‐wildtype glioblastoma

Authors: Higa, Nayuta, Akahane, Toshiaki, Hamada, Taiji, Yonezawa, Hajime, Uchida, Hiroyuki, Makino, Ryutaro, Watanabe, Shoji, Takajo, Tomoko, Yokoyama, Seiya, Kirishima, Mari, Matsuo, Kei, Fujio, Shingo, Hanaya, Ryosuke, Tanimoto, Akihide, Yoshimoto, Koji

Source: Cancer medicine. 12(1):49-60

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187842119.0x000001&indx=1&recIds=ETOCvdc_100187842119.0x000001

Characterization and treatment of gemcitabine‐ and cisplatin‐resistant bladder cancer cells with a pan‐RAS inhibitor

Authors: Yoshino, Hirofumi, Yokoyama, Seiya, Tamai, Motoki, Okamura, Shunsuke, Iizasa, Sayaka, Sakaguchi, Takashi, Osako, Yoichi, Inoguchi, Satoru, Matsushita, Ryosuke, Yamada, Yasutoshi, Nakagawa, Masayuki, Tatarano, Shuichi, Tanimoto, Akihide, Enokida, Hideki

Source: FEBS open bio. 13(6):1056-1066

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184659013.0x000001&indx=1&recIds=ETOCvdc_100184659013.0x000001

Targeting Heat Shock Transcription Factor 4 Enhances the Efficacy of Cabozantinib and Immune Checkpoint Inhibitors in Renal Cell Carcinoma.

Authors: Saito, Saeki, Yoshino, Hirofumi, Yokoyama, Seiya, Tominaga, Mitsuhiko, Li, Gang, Arima, Junya, Kawahara, Ichiro, Fukuda, Ikumi, Mitsuke, Akihiko, Sakaguchi, Takashi, Inoguchi, Satoru, Matsushita, Ryosuke, Yamada, Yasutoshi, Tatarano, Shuichi, Tanimoto, Akihide, Enokida, Hideki

Source: International Journal of Molecular Sciences; Feb2025, Vol. 26 Issue 4, p1776, 15p

Subject Terms: HEAT shock factors, IMMUNE checkpoint inhibitors, VASCULAR endothelial growth factors, RENAL cell carcinoma, PROTEIN-tyrosine kinase inhibitors

Electroporation Induces Unexpected Alterations in Gene Expression: A Tip for Selection of Optimal Transfection Method.

Authors: Hamada, Taiji, Yokoyama, Seiya, Akahane, Toshiaki, Matsuo, Kei, Kitazono, Ikumi, Furukawa, Tatsuhiko, Tanimoto, Akihide

Source: Current Issues in Molecular Biology; Feb2025, Vol. 47 Issue 2, p91, 15p

One-hundred-nm-scale electronic structure and transport calculations of organic polymers on the K computer

Authors: Imachi, Hiroto, Yokoyama, Seiya, Kaji, Takami, Abe, Yukiya, Tada, Tomofumi, Hoshi, Takeo

Subject Terms: Condensed Matter - Materials Science

Access URL: http://arxiv.org/abs/1603.09616

PCP4/PEP19 downregulates neurite outgrowth via transcriptional regulation of Ascl1 and NeuroD1 expression in human neuroblastoma M17 cells

Authors: Kitazono, Ikumi, Hamada, Taiji, Yoshimura, Takuya, Kirishima, Mari, Yokoyama, Seiya, Akahane, Toshiaki, Tanimoto, Akihide

Source: In Laboratory Investigation December 2020 100(12):1551-1563

Novel linear algebraic theory and one-hundred-million-atom quantum material simulations on the K computer

Authors: Hoshi, Takeo, Sogabe, Tomohiro, Miyatad, Takafumi, Lee, Dongjin, Zhang, Shao-Liang, Imachi, Hiroto, Kawai, Yoshifumi, Akiyama, Yohei, Yamazaki, Keita, Yokoyama, Seiya

Subject Terms: Condensed Matter - Materials Science, Physics - Computational Physics

Access URL: http://arxiv.org/abs/1402.7285

'Surface epithelial slackening' pattern in endometrioid carcinoma: A morphological feature for differentiating the POLE mutation-subtype from the no specific molecular profile subtype

Authors: Kitazono, Ikumi, Akahane, Toshiaki, Yokoyama, Seiya, Kobayashi, Yusuke, Togami, Shinichi, Yanazume, Shintaro, Tasaki, Takashi, Noguchi, Hirotsugu, Tabata, Kazuhiro, Kobayashi, Hiroaki, Tanimoto, Akihide

Source: Pathology, research and practice. 247

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193883652.0x000001&indx=1&recIds=ETOCvdc_100193883652.0x000001

A tailored next‐generation sequencing panel identified distinct subtypes of wildtype IDH and TERT promoter glioblastomas

Authors: Higa, Nayuta, Akahane, Toshiaki, Yokoyama, Seiya, Yonezawa, Hajime, Uchida, Hiroyuki, Takajo, Tomoko, Kirishima, Mari, Hamada, Taiji, Matsuo, Kei, Fujio, Shingo, Hanada, Tomoko, Hosoyama, Hiroshi, Yonenaga, Masanori, Sakamoto, Akihisa, Hiraki, Tsubasa, Tanimoto, Akihide, Yoshimoto, Koji

Source: Cancer science. 111(10):3902-3911

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100109047500.0x000001&indx=1&recIds=ETOCvdc_100109047500.0x000001

Genome Editing Using Cas9 Ribonucleoprotein Is Effective for Introducing PDGFRA Variant in Cultured Human Glioblastoma Cell Lines.

Authors: Hamada, Taiji¹ (AUTHOR), Yokoyama, Seiya¹ (AUTHOR), Akahane, Toshiaki¹ (AUTHOR), Matsuo, Kei¹ (AUTHOR), Tanimoto, Akihide¹ (AUTHOR) akit09@m3.kufm.kagoshima-u.ac.jp

Source: International Journal of Molecular Sciences. Jan2023, Vol. 24 Issue 1, p500. 13p.

Subject Terms: *GENOME editing, *CRISPRS, *CELL lines, *PLASMIDS, *PLATELET-derived growth factor receptors, *CANCER cell analysis

Assessment of tumor characteristics based on glycoform analysis of membrane-tethered MUC1

Authors: Matsuda, Atsushi, Higashi, Michiyo, Nakagawa, Tomomi, Yokoyama, Seiya, Kuno, Atsushi, Yonezawa, Suguru, Narimatsu, Hisashi

Source: In Laboratory Investigation September 2017 97(9):1103-1113

Gallbladder microbiota composition is associated with pancreaticobiliary and gallbladder cancer prognosis.

Authors: Kirishima, Mari¹ (AUTHOR), Yokoyama, Seiya¹ (AUTHOR), Matsuo, Kei¹ (AUTHOR), Hamada, Taiji¹ (AUTHOR), Shimokawa, Michiko¹ (AUTHOR), Akahane, Toshiaki¹ (AUTHOR), Sugimoto, Tomoyuki² (AUTHOR), Tsurumaru, Hirohito³ (AUTHOR), Ishibashi, Matsujiro³ (AUTHOR), Mataki, Yuko⁴ (AUTHOR), Ootsuka, Takao⁴ (AUTHOR), Nomoto, Mitsuharu¹ (AUTHOR), Hayashi, Chihiro⁵ (AUTHOR), Horiguchi, Akihiko⁵ (AUTHOR), Higashi, Michiyo¹ (AUTHOR), Tanimoto, Akihide¹ (AUTHOR) akit09@m3.kufm.kagoshima-u.ac.jp

Source: BMC Microbiology. 5/27/2022, Vol. 22 Issue 1, p1-12. 12p.

Subject Terms: *GALLBLADDER cancer, *BREAST cancer prognosis, *GALLBLADDER, *CANCER prognosis, *CHOLANGIOCARCINOMA, *LYMPHATIC metastasis, *OVERALL survival

Exercise Suppresses Head and Neck Squamous Cell Carcinoma Growth via Oncostatin M.

Authors: Yoshimura, Takuya, Hirano, Yuka, Hamada, Taiji, Yokoyama, Seiya, Suzuki, Hajime, Takayama, Hirotaka, Migita, Hirono, Ishida, Takayuki, Nakamura, Yasunori, Ohsawa, Masahiro, Asakawa, Akihiro, Ishihata, Kiyohide, Tanimoto, Akihide

Source: Cancers; Mar2024, Vol. 16 Issue 6, p1187, 12p

Subject Terms: SQUAMOUS cell carcinoma, SURVIVAL, MOUTH tumors, RESEARCH funding, EXERCISE therapy, HEAD & neck cancer, ENZYME-linked immunosorbent assay, CELL proliferation, METASTASIS, ANIMAL experimentation, CYTOKINES, CELL survival, DISEASE progression, MYOKINES, SARCOPENIA

Next-generation sequencing analysis of endometrial screening liquid-based cytology specimens: a comparative study to tissue specimens

Authors: Akahane, Toshiaki, Kitazono, Ikumi, Yanazume, Shintaro, Kamio, Masaki, Togami, Shinichi, Sakamoto, Ippei, Nohara, Sachio, Yokoyama, Seiya, Kobayashi, Hiroaki, Hiraki, Tsubasa, Suzuki, Shinsuke, Ueno, Shinichi, Tanimoto, Akihide

Source: BMC medical genomics. 13(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171930274.0x000001&indx=1&recIds=ETOCvdc_100171930274.0x000001

Mucin Expression in Endoscopic Ultrasound-Guided Fine-Needle Aspiration Specimens Is a Useful Prognostic Factor in Pancreatic Ductal Adenocarcinoma

Authors: Higashi, Michiyo, Yokoyama, Seiya, Yamamoto, Takafumi, Goto, Yuko, Kitazono, Ikumi, Hiraki, Tsubasa, Taguchi, Hiroki, Hashimoto, Shinichi, Fukukura, Yoshihiko, Koriyama, Chihaya, Mataki, Yuko, Maemura, Kosei, Shinchi, Hiroyuki, Jain, Maneesh, Batra, Surinder K., Yonezawa, Suguru

Source: Pancreas. 44(5):728-734

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100037070451.0x000001&indx=1&recIds=ETOCvdc_100037070451.0x000001

Identification of Neck Lymph Node Metastasis-Specific microRNA—Implication for Use in Monitoring or Prediction of Neck Lymph Node Metastasis.

Authors: Higashi, Yutaro, Nakamura, Kodai, Takaoka, Ryota, Tani, Mika, Noma, Yusaku, Mori, Kazuki, Yamashiro, Kota, Yokoyama, Seiya, Hamada, Tomofumi, Sugiura, Tsuyoshi

Source: Cancers; Aug2023, Vol. 15 Issue 15, p3769, 17p

Subject Terms: HEAD & neck cancer diagnosis, METASTASIS, LYMPH nodes, MICRORNA, HEAD & neck cancer, REGRESSION analysis, CANCER patients, COMPARATIVE studies, DESCRIPTIVE statistics, RESEARCH funding, TUMOR markers, POLYMERASE chain reaction, SENSITIVITY & specificity (Statistics), SQUAMOUS cell carcinoma

Motor

MALAT1 functions as a transcriptional promoter of MALAT1::GLI1 fusion for truncated GLI1 protein expression in cancer.

Authors: Hamada, Taiji, Higashi, Michiyo, Yokoyama, Seiya, Akahane, Toshiaki, Hisaoka, Masanori, Noguchi, Hirotsugu, Furukawa, Tatsuhiko, Tanimoto, Akihide

Source: BMC Cancer; 5/10/2023, Vol. 23 Issue 1, p1-12, 12p

Subject Terms: PROTEIN expression, GENE fusion, GENE expression, LINCRNA, BINDING sites