A Case of Primary Lung Adenocarcinoma With Recurrent Brain Metastasis due to Transformation to Small Cell Carcinoma During Adjuvant Atezolizumab Therapy

Authors: Nao Kobayashi, Noriaki Sunaga, Masakiyo Yatomi, Ikuo Wakamatsu, Sohei Muto, Hayato Ikota, Rei Yamaguchi, Yoichi Ohtaki, Toshiteru Nagashima, Nobuteru Kubo, Tomomi Masuda, Yosuke Miura, Hiroaki Tsurumaki, Reiko Sakurai, Yasuhiko Koga, Takeshi Hisada, Toshitaka Maeno

Source: Thoracic Cancer, Vol 16, Iss 2, Pp n/a-n/a (2025)

Subject Terms: adenocarcinoma, immune checkpoint inhibitor, non‐small cell lung cancer, small cell lung cancer, therapeutic resistance, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1759-7706; https://doaj.org/toc/1759-7714

Access URL: https://doaj.org/article/223533b8458f46a8b552a1b86ec0393a

Prognosis of non‐small cell lung cancer with postoperative regional lymph node recurrence

Authors: Yoichi Ohtaki, Toshiteru Nagashima, Naoko Okano, Nobuteru Kubo, Takeru Ohtaka, Noriaki Sunaga, Reiko Sakurai, Yosuke Miura, Seshiru Nakazawa, Natsuko Kawatani, Tomohiro Yazawa, Ryohei Yoshikawa, Eiji Narusawa, Ken Shirabe

Source: Thoracic Cancer, Vol 15, Iss 11, Pp 859-866 (2024)

Subject Terms: chemoradiotherapy, driver gene, lymph node recurrence, non‐small cell lung cancer (NSCLC), radiotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1759-7706; https://doaj.org/toc/1759-7714

Access URL: https://doaj.org/article/dc8c1c5ac6b64107ac18af0dd6e3b070

Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome‐wide association and whole genome sequencing analyses

Authors: Kouya Shiraishi, Atsushi Takahashi, Yukihide Momozawa, Yataro Daigo, Syuzo Kaneko, Takahisa Kawaguchi, Hideo Kunitoh, Shingo Matsumoto, Hidehito Horinouchi, Akiteru Goto, Takayuki Honda, Kimihiro Shimizu, Masahiro Torasawa, Daisuke Takayanagi, Motonobu Saito, Akira Saito, Yuichiro Ohe, Shun‐ichi Watanabe, Koichi Goto, Masahiro Tsuboi, Katsuya Tsuchihara, Sadaaki Takata, Tomomi Aoi, Atsushi Takano, Masashi Kobayashi, Yohei Miyagi, Kazumi Tanaka, Hiroyuki Suzuki, Daichi Maeda, Takumi Yamaura, Maiko Matsuda, Yoko Shimada, Takaaki Mizuno, Hiromi Sakamoto, Teruhiko Yoshida, Yasushi Goto, Tatsuya Yoshida, Taiki Yamaji, Makoto Sonobe, Shinichi Toyooka, Kazue Yoneda, Katsuhiro Masago, Fumihiro Tanaka, Megumi Hara, Nobuo Fuse, Satoshi S. Nishizuka, Noriko Motoi, Norie Sawada, Yuichiro Nishida, Kazuki Kumada, Kenji Takeuchi, Kozo Tanno, Yasushi Yatabe, Kuniko Sunami, Tomoyuki Hishida, Yasunari Miyazaki, Hidemi Ito, Mitsuhiro Amemiya, Hirohiko Totsuka, Haruhiko Nakayama, Tomoyuki Yokose, Kazuyoshi Ishigaki, Toshiteru Nagashima, Yoichi Ohtaki, Kazuhiro Imai, Ken Takasawa, Yoshihiro Minamiya, Kazuma Kobayashi, Kenichi Okubo, Kenji Wakai, Atsushi Shimizu, Masayuki Yamamoto, Motoki Iwasaki, Koichi Matsuda, Johji Inazawa, Yuichi Shiraishi, Hiroyoshi Nishikawa, Yoshinori Murakami, Michiaki Kubo, Fumihiko Matsuda, Yoichiro Kamatani, Ryuji Hamamoto, Keitaro Matsuo, Takashi Kohno

Source: Cancer Communications, Vol 44, Iss 2, Pp 287-293 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2523-3548

Access URL: https://doaj.org/article/a4b8ea6db19942899046a4b6375483b8

The oncogenic role of LGR6 overexpression induced by aberrant Wnt/β‐catenin signaling in lung cancer

Authors: Noriaki Sunaga, Kyoichi Kaira, Kimihiro Shimizu, Ichidai Tanaka, Yosuke Miura, Seshiru Nakazawa, Yoichi Ohtaki, Reika Kawabata‐Iwakawa, Mitsuo Sato, Luc Girard, John D. Minna, Takeshi Hisada

Source: Thoracic Cancer, Vol 15, Iss 2, Pp 131-141 (2024)

Subject Terms: non‐small cell lung cancer, oncogene, small cell lung cancer, Wnt pathway, β‐catenin, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1759-7706; https://doaj.org/toc/1759-7714

Access URL: https://doaj.org/article/5f3ac49b46674432a77218e09361baf5

Autoimmune alopecia areata due to thymoma without myasthenia gravis: a case report

Authors: Yukino Saito, Tomohiro Yazawa, Toshiteru Nagashima, Yoichi Ohtaki, Natsuko Kawatani, Eiji Narusawa, Ryohei Yoshikawa, Nozomi Matsumura, Tatsuro Maehara, Ken Shirabe

Source: Surgical Case Reports, Vol 9, Iss 1, Pp 1-4 (2023)

Subject Terms: Thymoma, Alopecia areata, Surgery, Autoimmune disease, RD1-811

File Description: electronic resource

Relation: https://doaj.org/toc/2198-7793

Access URL: https://doaj.org/article/dc469c8095234a0691e06e66229fb663

Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

Authors: Jianxin Shi, Kouya Shiraishi, Jiyeon Choi, Keitaro Matsuo, Tzu-Yu Chen, Juncheng Dai, Rayjean J. Hung, Kexin Chen, Xiao-Ou Shu, Young Tae Kim, Maria Teresa Landi, Dongxin Lin, Wei Zheng, Zhihua Yin, Baosen Zhou, Bao Song, Jiucun Wang, Wei Jie Seow, Lei Song, I-Shou Chang, Wei Hu, Li-Hsin Chien, Qiuyin Cai, Yun-Chul Hong, Hee Nam Kim, Yi-Long Wu, Maria Pik Wong, Brian Douglas Richardson, Karen M. Funderburk, Shilan Li, Tongwu Zhang, Charles Breeze, Zhaoming Wang, Batel Blechter, Bryan A. Bassig, Jin Hee Kim, Demetrius Albanes, Jason Y. Y. Wong, Min-Ho Shin, Lap Ping Chung, Yang Yang, She-Juan An, Hong Zheng, Yasushi Yatabe, Xu-Chao Zhang, Young-Chul Kim, Neil E. Caporaso, Jiang Chang, James Chung Man Ho, Michiaki Kubo, Yataro Daigo, Minsun Song, Yukihide Momozawa, Yoichiro Kamatani, Masashi Kobayashi, Kenichi Okubo, Takayuki Honda, Dean H. Hosgood, Hideo Kunitoh, Harsh Patel, Shun-ichi Watanabe, Yohei Miyagi, Haruhiko Nakayama, Shingo Matsumoto, Hidehito Horinouchi, Masahiro Tsuboi, Ryuji Hamamoto, Koichi Goto, Yuichiro Ohe, Atsushi Takahashi, Akiteru Goto, Yoshihiro Minamiya, Megumi Hara, Yuichiro Nishida, Kenji Takeuchi, Kenji Wakai, Koichi Matsuda, Yoshinori Murakami, Kimihiro Shimizu, Hiroyuki Suzuki, Motonobu Saito, Yoichi Ohtaki, Kazumi Tanaka, Tangchun Wu, Fusheng Wei, Hongji Dai, Mitchell J. Machiela, Jian Su, Yeul Hong Kim, In-Jae Oh, Victor Ho Fun Lee, Gee-Chen Chang, Ying-Huang Tsai, Kuan-Yu Chen, Ming-Shyan Huang, Wu-Chou Su, Yuh-Min Chen, Adeline Seow, Jae Yong Park, Sun-Seog Kweon, Kun-Chieh Chen, Yu-Tang Gao, Biyun Qian, Chen Wu, Daru Lu, Jianjun Liu, Ann G. Schwartz, Richard Houlston, Margaret R. Spitz, Ivan P. Gorlov, Xifeng Wu, Ping Yang, Stephen Lam, Adonina Tardon, Chu Chen, Stig E. Bojesen, Mattias Johansson, Angela Risch, Heike Bickeböller, Bu-Tian Ji, H-Erich Wichmann, David C. Christiani, Gadi Rennert, Susanne Arnold, Paul Brennan, James McKay, John K. Field, Sanjay S. Shete, Loic Le Marchand, Geoffrey Liu, Angeline Andrew, Lambertus A. Kiemeney, Shan Zienolddiny-Narui, Kjell Grankvist, Mikael Johansson, Angela Cox, Fiona Taylor, Jian-Min Yuan, Philip Lazarus, Matthew B. Schabath, Melinda C. Aldrich, Hyo-Sung Jeon, Shih Sheng Jiang, Jae Sook Sung, Chung-Hsing Chen, Chin-Fu Hsiao, Yoo Jin Jung, Huan Guo, Zhibin Hu, Laurie Burdett, Meredith Yeager, Amy Hutchinson, Belynda Hicks, Jia Liu, Bin Zhu, Sonja I. Berndt, Wei Wu, Junwen Wang, Yuqing Li, Jin Eun Choi, Kyong Hwa Park, Sook Whan Sung, Li Liu, Chang Hyun Kang, Wen-Chang Wang, Jun Xu, Peng Guan, Wen Tan, Chong-Jen Yu, Gong Yang, Alan Dart Loon Sihoe, Ying Chen, Yi Young Choi, Jun Suk Kim, Ho-Il Yoon, In Kyu Park, Ping Xu, Qincheng He, Chih-Liang Wang, Hsiao-Han Hung, Roel C. H. Vermeulen, Iona Cheng, Junjie Wu, Wei-Yen Lim, Fang-Yu Tsai, John K. C. Chan, Jihua Li, Hongyan Chen, Hsien-Chih Lin, Li Jin, Jie Liu, Norie Sawada, Taiki Yamaji, Kathleen Wyatt, Shengchao A. Li, Hongxia Ma, Meng Zhu, Zhehai Wang, Sensen Cheng, Xuelian Li, Yangwu Ren, Ann Chao, Motoki Iwasaki, Junjie Zhu, Gening Jiang, Ke Fei, Guoping Wu, Chih-Yi Chen, Chien-Jen Chen, Pan-Chyr Yang, Jinming Yu, Victoria L. Stevens, Joseph F. Fraumeni, Nilanjan Chatterjee, Olga Y. Gorlova, Chao Agnes Hsiung, Christopher I. Amos, Hongbing Shen, Stephen J. Chanock, Nathaniel Rothman, Takashi Kohno, Qing Lan

Source: Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/91497ad90e1e4c55a94f6aaf69b16ba4

Durable response to afatinib rechallenge in a long‐term survivor of non‐small cell lung cancer harboring EGFR L858R and L747V mutations

Authors: Mio Kanbe, Noriaki Sunaga, Kenichiro Hara, Hiiru Sawada, Ikuo Wakamatsu, Kentaro Hara, Sohei Muto, Yuri Sawada, Hiroaki Masubuchi, Mari Sato, Yosuke Miura, Hiroaki Tsurumaki, Masakiyo Yatomi, Reiko Sakurai, Yasuhiko Koga, Yoichi Ohtaki, Toshiteru Nagashima, Naoko Okano, Nobuteru Kubo, Toshitaka Maeno, Takeshi Hisada

Source: Thoracic Cancer, Vol 13, Iss 22, Pp 3225-3228 (2022)

Subject Terms: afatinib, epidermal growth factor receptor, progression‐free survival, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1759-7706; https://doaj.org/toc/1759-7714

Access URL: https://doaj.org/article/d6b392ec2974405a97ac8b33a3e7d1f8

Video-assisted thoracoscopic segmentectomy with combined chest wall resection: A case report

Authors: Yoichi Ohtaki, Toshiki Yajima, Kai Obayashi, Seshiru Nakazawa, Hayato Ikota, Ken Shirabe

Source: Journal of Cardiothoracic Surgery, Vol 17, Iss 1, Pp 1-4 (2022)

Subject Terms: Lung cancer, Video-assisted thoracoscopic surgery, Segmentectomy, Chest wall, Surgery, RD1-811, Anesthesiology, RD78.3-87.3

File Description: electronic resource

Relation: https://doaj.org/toc/1749-8090

Access URL: https://doaj.org/article/b075eef6e03245a2a7c2100e105bed44

Clinical and anatomical features of the lateral costal artery and vein

Authors: Seshiru Nakazawa, Natsuko Kawatani, Kai Obayashi, Yoichi Ohtaki, Tomokazu Ito, Toshiki Yajima, Ken Shirabe

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/8418f49f90ff449f9113d53d874c04ae

Comprehensive expressional analysis of chemosensitivity‐related markers in large cell neuroendocrine carcinoma of the lung

Authors: Yoichi Ohtaki, Kyoichi Kaira, Toshiki Yajima, Bilguun Erkhem‐Ochir, Osamu Kawashima, Mitsuhiro Kamiyoshihara, Hitoshi Igai, Ryoichi Onozato, Takashi Ibe, Takayuki Kosaka, Seshiru Nakazawa, Toshiteru Nagashima, Tetsunari Oyama, Ken Shirabe

Source: Thoracic Cancer, Vol 12, Iss 20, Pp 2666-2679 (2021)

Subject Terms: chemosensitivity, large cell neuroendocrine carcinoma, lung cancer, thymidylate synthase, topoisomerase II, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1759-7706; https://doaj.org/toc/1759-7714

Access URL: https://doaj.org/article/e29d209aeacb49aeb4152324c238fa38

Ectopic thymoma in the paratracheal region of the middle mediastinum: a rare case report and literature review

Authors: Toshiki Yajima, Akira Mogi, Kimihiro Shimizu, Takayuki Kosaka, Toshiteru Nagashima, Yoichi Ohtaki, Kai Obayashi, Seshiru Nakazawa, Misaki Iijima, Yuka Yoshida, Junko Hirato, Hiroyuki Kuwano

Source: BMC Research Notes, Vol 11, Iss 1, Pp 1-5 (2018)

Subject Terms: Ectopic thymoma, Middle mediastinal tumor, Ectopic thymus, Paratracheal nodule, Medicine, Biology (General), QH301-705.5, Science (General), Q1-390

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13104-018-3359-9; https://doaj.org/toc/1756-0500

Access URL: https://doaj.org/article/c1c651dc94214d1db2a093a8f89f6cb1

Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma

Authors: Kouya Shiraishi, Yukinori Okada, Atsushi Takahashi, Yoichiro Kamatani, Yukihide Momozawa, Kyota Ashikawa, Hideo Kunitoh, Shingo Matsumoto, Atsushi Takano, Kimihiro Shimizu, Akiteru Goto, Koji Tsuta, Shun-ichi Watanabe, Yuichiro Ohe, Yukio Watanabe, Yasushi Goto, Hiroshi Nokihara, Koh Furuta, Akihiko Yoshida, Koichi Goto, Tomoyuki Hishida, Masahiro Tsuboi, Katsuya Tsuchihara, Yohei Miyagi, Haruhiko Nakayama, Tomoyuki Yokose, Kazumi Tanaka, Toshiteru Nagashima, Yoichi Ohtaki, Daichi Maeda, Kazuhiro Imai, Yoshihiro Minamiya, Hiromi Sakamoto, Akira Saito, Yoko Shimada, Kuniko Sunami, Motonobu Saito, Johji Inazawa, Yusuke Nakamura, Teruhiko Yoshida, Jun Yokota, Fumihiko Matsuda, Keitaro Matsuo, Yataro Daigo, Michiaki Kubo, Takashi Kohno

Source: Nature Communications, Vol 7, Iss 1, Pp 1-7 (2016)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/06abe374e88a4c0f861cb8193ced8a5f

Highly sensitive detection of a HER2 12-base pair duplicated insertion mutation in lung cancer using the Eprobe-PCR method.

Authors: Yoshiaki Takase, Kengo Usui, Kimihiro Shimizu, Yasumasa Kimura, Tatsuo Ichihara, Takahiro Ohkawa, Jun Atsumi, Yasuaki Enokida, Seshiru Nakazawa, Kai Obayashi, Yoichi Ohtaki, Toshiteru Nagashima, Yasumasa Mitani, Izumi Takeyoshi

Source: PLoS ONE, Vol 12, Iss 2, p e0171225 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0171225&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/6569c880dde0404f931ab6ee0fa2ad93

Pyothorax and Constrictive Pericarditis after Chemoradiotherapy for Esophageal Cancer.

Authors: Yohei Ishibashi, Noriaki Takama, Yoichi Ohtaki, Norimichi Koitabashi, Masahiko Kurabayashi, Hideki Ishii

Source: Internal Medicine; 2024, Vol. 63 Issue 10, p1387-1393, 7p

Postrecurrence survival of surgically resected pulmonary adenocarcinoma patients according to EGFR and KRAS mutation status.

Authors: YOICHI OHTAKI¹, KIMIHIRO SHIMIZU¹ kmshimizu@gmail.com, SEIICHI KAKEGAWA¹, TOSHITERU NAGASHIMA¹, TETSUHIRO NAKANO¹, JUN ATSUMI¹, YASUAKI ENOKIDA¹, HITOSHI IGAI¹, TAKASHI IBE¹, MASAYUKI SUGANO¹, MITSUHIRO KAMIYOSHIHARA¹, OSAMU KAWASHIMA¹, KYOICHI KAIRA², NORIAKI SUNAGA², IZUMI TAKEYOSHI¹

Source: Molecular & Clinical Oncology. 2014, Vol. 2 Issue 3, p187-196. 10p.

Subject Terms: *ADENOCARCINOMA, *LUNG cancer, *EPIDERMAL growth factor receptors, *ONCOGENES, TUMOR genetics

Single-nucleotide polymorphism (c.309T>G) in the MDM2 gene and lung cancer risk.

Authors: YASUAKI ENOKIDA, KIMIHIRO SHIMIZU, SEIICHI KAKEGAWA, JUN ATSUMI, YOSHIAKI TAKASE, YOHEI MIYAMAE, TOSHITERU NAGASHIMA, YOICHI OHTAKI, KYOICHI KAIRA, NORIAKI SUNAGA, NORIKO YANAGITANI, REIKO YOSHINO, KATSUHIKO TSUNEKAWA, HITOSHI IGAI, MITSUHIRO KAMIYOSHIHARA, KENGO USUI, LEZHAVA, ALEXANDER, YOSHIO TOMIZAWA, TOSHIHISA ISHIKAWA, MASAMI MURAKAMI

Source: Biomedical Reports; 2014, Vol. 2 Issue 5, p719-724, 6p

Subject Terms: SINGLE nucleotide polymorphisms, GENES, LUNG cancer, ALLELES, GENETIC polymorphisms