Human and mouse proteomics reveals the shared pathways in Alzheimer’s disease and delayed protein turnover in the amyloidome

Authors: Jay M. Yarbro, Xian Han, Abhijit Dasgupta, Ka Yang, Danting Liu, Him K. Shrestha, Masihuz Zaman, Zhen Wang, Kaiwen Yu, Dong Geun Lee, David Vanderwall, Mingming Niu, Huan Sun, Boer Xie, Ping-Chung Chen, Yun Jiao, Xue Zhang, Zhiping Wu, Surendhar R. Chepyala, Yingxue Fu, Yuxin Li, Zuo-Fei Yuan, Xusheng Wang, Suresh Poudel, Barbora Vagnerova, Qianying He, Andrew Tang, Patrick T. Ronaldson, Rui Chang, Gang Yu, Yansheng Liu, Junmin Peng

Source: Nature Communications, Vol 16, Iss 1, Pp 1-16 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/eb7e187ca0ce475e8bb891e8fcbe46c3

A computational tool to infer enzyme activity using post-translational modification profiling data

Authors: Dehui Kong, Aijun Zhang, Ling Li, Zuo-Fei Yuan, Yingxue Fu, Long Wu, Ashutosh Mishra, Anthony A. High, Junmin Peng, Xusheng Wang

Source: Communications Biology, Vol 8, Iss 1, Pp 1-8 (2025)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/bcee18af6025428796dc249b3dbe544d

Author Correction: Treadmill training improves lung function and inhibits alveolar cell apoptosis in spinal cord injured rats

Authors: Xianbin Wang, Yingxue Fu, Xianglian Yang, Yan Chen, Ni Zeng, Shouxing Hu, Shuai Ouyang, Xiao Pan, Shuang Wu

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-4 (2025)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/fd01520df48e4eb9bb33ad08827e9348

Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI complex homeostasis in neurons

Authors: Xiaoting Zhou, You-Kyung Lee, Xianting Li, Henry Kim, Carlos Sanchez-Priego, Xian Han, Haiyan Tan, Suiping Zhou, Yingxue Fu, Kerry Purtell, Qian Wang, Gay R. Holstein, Beisha Tang, Junmin Peng, Nan Yang, Zhenyu Yue

Source: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/71903ec458994596b1e2fc44fc246235

Treadmill training improves lung function and inhibits alveolar cell apoptosis in spinal cord injured rats

Authors: Xianbin Wang, Yingxue Fu, Xianglian Yang, Yan Chen, Ni Zeng, Shouxing Hu, Shuai Ouyang, Xiao Pan, Shuang Wu

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)

Subject Terms: Spinal cord injury, Lung injury, Treadmill training, miR145-5p, MAP3K3, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/486b75b80a384e72aea522e6a9dfc09b

An adaptive stress response that confers cellular resilience to decreased ubiquitination

Authors: Liam C. Hunt, Vishwajeeth Pagala, Anna Stephan, Boer Xie, Kiran Kodali, Kanisha Kavdia, Yong-Dong Wang, Abbas Shirinifard, Michelle Curley, Flavia A. Graca, Yingxue Fu, Suresh Poudel, Yuxin Li, Xusheng Wang, Haiyan Tan, Junmin Peng, Fabio Demontis

Source: Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/ecc3809ff4864ac888167d9faaecd3c0

PEAC: An Ultrasensitive and Cost-Effective MRD Detection System in Non-small Cell Lung Cancer Using Plasma Specimen

Authors: Jianping Xu, Yue Pu, Rui Lin, Shanshan Xiao, Yingxue Fu, Tao Wang

Source: Frontiers in Medicine, Vol 9 (2022)

Subject Terms: liquid biopsy, CtDNA, ddPCR, NGS, PEAC, MRD, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2022.822200/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/eee666f4213f4040ba3863afde7c78c2

Research on the Selective Electrocatalytic Reduction of SO2 to Recover S0 by Pb Electrode

Authors: Xudong Liu, Xiaoyang Wang, Jiaqi Long, Xiaofeng Xie, Lin Wu, Zhujiang Wang, Yingxue Fu, Hao Chen, Kaisong Xiang, Hui Liu

Source: Metals, Vol 13, Iss 3, p 569 (2023)

Subject Terms: Pb, SO2, S0, surfactant, sulfur adhesion, Mining engineering. Metallurgy, TN1-997

File Description: electronic resource

Relation: https://www.mdpi.com/2075-4701/13/3/569; https://doaj.org/toc/2075-4701

Access URL: https://doaj.org/article/634f772de82e406ba6e8bc743cee1255

Integrated Multiomics Analyses Revealing Different Molecular Profiles Between Early- and Late-Stage Lung Adenocarcinoma

Authors: Dongsheng Yue, Weiran Liu, Liuwei Gao, Lianmin Zhang, Tao Wang, Shanshan Xiao, Yingxue Fu, Nan Li, Rui Lin, Yao Hu, Lieming Ding, Zhenfa Zhang, Bin Zhang, Changli Wang

Source: Frontiers in Oncology, Vol 11 (2021)

Subject Terms: lung adenocarcinoma, whole-genome sequencing, RNA-seq, ATAC-seq, integrated multi-omics analyses, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2021.746943/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/a4d697d4ec9e407c91674a9acb947a7a

Systematic Evaluation of the Diagnostic and Prognostic Significance of Competitive Endogenous RNA Networks in Prostate Cancer

Authors: Zihu Guo, Liang Han, Yingxue Fu, Ziyin Wu, Yaohua Ma, Yueping Li, Haiqing Wang, Li Jiang, Shengnan Liang, Zhenzhong Wang, Furong Li, Wei Xiao, Jingbo Wang, Yonghua Wang

Source: Frontiers in Genetics, Vol 11 (2020)

Subject Terms: prostate cancer, ceRNA network, diagnostic model, prognosis, bioinformatics analysis, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fgene.2020.00785/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/64a54980eff146ec8c542f685d647b74

Deciphering the multicomponent synergy mechanism from a systems pharmacology perspective: Application to Gualou Xiebai Decoction for coronary heart disease

Authors: Yang Yang, Chao Huang, Xing Su, Jinglin Zhu, Xuetong Chen, Yingxue Fu, Zhenzhong Wang, Jun Zhou, Wei Xiao, Chunli Zheng, Yonghua Wang

Source: Journal of Functional Foods, Vol 47, Iss , Pp 143-155 (2018)

Subject Terms: Systems pharmacology, Synergy, Gualou Xiebai Decoction, Coronary heart disease, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1756464618300756; https://doaj.org/toc/1756-4646

Access URL: https://doaj.org/article/b0179505b31b43c0b697d39de305f6f9

Systems pharmacology uncovers serotonergic pathway mediated psychotherapeutic effects of Lonicerae Japonicae Flos

Authors: Ziyin Wu, Liyang Chen, Zihu Guo, Kaiyue Li, Yingxue Fu, Jinglin Zhu, Xuetong Chen, Chao Huang, Chunli Zheng, Yaohua Ma, Xiaogang Li, Jun Zhou, Zhenzhong Wang, Wei Xiao, Yonghua Wang

Source: Journal of Functional Foods, Vol 60, Iss , Pp - (2019)

Subject Terms: Psychiatric disorder, Complementary and alternative therapies, Lonicerae Japonicae Flos, Systems pharmacology, RNA-Seq, Serotonergic pathway, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1756464619303251; https://doaj.org/toc/1756-4646

Access URL: https://doaj.org/article/cc5bc16023c347cca44fc18c2901a1b6

Systems-Mapping of Herbal Effects on Complex Diseases Using the Network-Perturbation Signatures

Authors: Xuetong Chen, Chunli Zheng, Chun Wang, Zihu Guo, Shuo Gao, Zhangchi Ning, Chao Huang, Cheng Lu, Yingxue Fu, Daogang Guan, Aiping Lu, Yonghua Wang

Source: Frontiers in Pharmacology, Vol 9 (2018)

Subject Terms: systems pharmacology, herbal medicines, perturbation signatures, network pharmacology, personalized medicine, mathematical modeling, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2018.01174/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/a0250ec15b8d45cd8cdf5ae80179f746

Systems pharmacology for traditional Chinese medicine with application to cardio-cerebrovascular diseases

Authors: Yingxue Fu, Yonghua Wang, Boli Zhang

Source: Journal of Traditional Chinese Medical Sciences, Vol 1, Iss 2, Pp 84-91 (2014)

Subject Terms: Systems pharmacology, Traditional Chinese medicine, Cardiovascular and cerebrovascular diseases, Systems biology, Miscellaneous systems and treatments, RZ409.7-999

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2095754815000083; https://doaj.org/toc/2095-7548

Access URL: https://doaj.org/article/0770ebbdcecd4358ba78c82928dfd112

JUMPn: A Streamlined Application for Protein Co-Expression Clustering and Network Analysis in Proteomics

Authors: David Vanderwall, author¹, Poudel Suresh, author^{1, 2}, Yingxue Fu, author², Ji-Hoon Cho, author², Timothy I. Shaw, author^{2, 3}, Ashutosh Mishra, author², Anthony A. High, author², Junmin Peng, author^{1, 2}, Yuxin Li, author^{1, 2}

Source: Journal of Visualized Experiments. (176)

Availability: http://www.jove.com/video/62796

Insights from systems pharmacology into cardiovascular drug discovery and therapy.

Authors: Peng Li¹ lpeng@nwsuaf.edu.cn, Yingxue Fu¹ 760587207@qq.com, Jinlong Ru¹ 527104360@qq.com, Chao Huang¹ 994625904@qq.com, Jiangfeng Du² j.du@maastrichtuniversity.nl, Chunli Zheng¹ 523041423@qq.com, Xuetong Chen¹ 908687194@qq.com, Pidong Li¹ 78956287@qq.com, Aiping Lu³ lap64067611@126.com, Ling Yang⁴ yling@dicp.ac.cn, Yonghua Wang¹ yh_wang@nwsuaf.edu.cn

Source: BMC Systems Biology. 2014, Vol. 8 Issue 1, p175-200. 26p.

Subject Terms: *PHARMACOLOGY, *CARDIOVASCULAR agents, *CARDIOVASCULAR disease treatment, *PROTEINS, *GENETIC pleiotropy, *ETIOLOGY of diseases

Weak-binding molecules are not drugs?-toward a systematic strategy for finding effective weak-binding drugs.

Authors: Jinan Wang¹, Zihu Guo¹, Yingxue Fu¹, Ziyin Wu¹, Chao Huang¹, Chunli Zheng¹, Piar Ali Shar¹, Zhenzhong Wang², Wei Xiao³, Yonghua Wang⁴, yh_wang@nwsuaf.edu.cn

Source: Briefings in Bioinformatics; Mar2017, Vol. 18 Issue 2, p321-332, 12p

Large-scale exploration and analysis of drug combinations.

Authors: Peng Li¹, Chao Huang¹, Yingxue Fu¹, Jinan Wang¹, Ziyin Wu¹, Jinlong Ru¹, Chunli Zheng¹, Zihu Guo¹, Xuetong Chen¹, Wei Zhou¹, Wenjuan Zhang¹, Yan Li², Jianxin Chen³, Aiping Lu⁴, Yonghua Wa¹, yh_wang@nwsuaf.edu.cn

Source: Bioinformatics; 6/15/2015, Vol. 31 Issue 12, p2007-2016, 10p

Systems pharmacology-based approach for dissecting the addition and subtraction theory of traditional Chinese medicine: An example using Xiao-Chaihu-Decoction and Da-Chaihu-Decoction.

Authors: Bohui Li^1,2, Weiyang Tao^1,2, Chunli Zheng^1,2, Shar, Piar Ali^2,3, Chao Huang^1,2, Yingxue Fu^1,2, Yonghua Wang^1,2, yh_wang@nwsuaf.edu.cn

Source: Computers in Biology & Medicine; Oct2014, Vol. 53, p19-29, 11p

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