Targeting FABP4/UCP2 axis to overcome cetuximab resistance in obesity-driven CRC with drug-tolerant persister cells

Authors: Cheng, Yi-Chiao ^{a, b}, Chen, Ming-Yao ^{c, d}, Yadav, Vijesh Kumar ^{c, d}, Pikatan, Narpati Wesa ^e, Fong, Iat-Hang ^{f, g}, Kuo, Kuang-Tai ^h, Yeh, Chi-Tai ^{f, g, ⁎}, Tsai, Jo-Ting ^{a, i, j, ⁎⁎}

Source: In Translational Oncology March 2025 53

S-hydroxychloroquine prevents the antiphospholipid thrombogenic complexes for antiphospholipid syndrome treatment

Authors: Hsieh, Ming-Shou ^{a, 1}, Liu, Heng-Wei ^{b, c, d, 1}, Guo, Fu-You ^e, Song, Deng-Pan ^e, Li, Meng-Yuan ^e, Chao, Tsu-Yi ^f, Fong, Iat-Hang ^{b, c, d}, Chang, Yu-Sheng ^{g, h, ⁎}, Yeh, Chi-Tai ^{a, i, ⁎⁎}

Source: In Biomedicine & Pharmacotherapy May 2025 186

Sphingosine-1-phosphate receptor 3 promotes neuronal apoptosis via the TNF-α/caspase-3 signaling pathway after acute intracerebral hemorrhage

Authors: Song, Dengpan, Li, Mengyuan, Zhang, Longxiao, Zhang, Kaiyuan, An, Yuan, Feng, Mengzhao, Wang, Fang, Yeh, Chi-Tai, Wang, Jian, Guo, Fuyou

Source: In Molecular and Cellular Neuroscience December 2024 131

Targeting the Neuropilin-1 receptor with Ovatodiolide and progress in using periodontal ligament organoids for COVID-19 research and therapy

Authors: Hsieh, Ming-Shou, Chen, Ming-Yao, Chang, Yu-Sheng, Huang, Chin-Sheng, Hsu, Tung-Nien, Huang, Mao-Suan, Yeh, Chi-Tai, Tzeng, Yew-Min

Source: In Life Sciences 15 August 2024 351

Therapeutic targeting of thioredoxin reductase 1 causes ferroptosis while potentiating anti-PD-1 efficacy in head and neck cancer

Authors: Hsieh, Ming-Shou, Ling, Hang Huong, Setiawan, Syahru Agung, Hardianti, Mardiah Suci, Fong, Iat-Hang, Yeh, Chi-Tai, Chen, Jia-Hong

Source: In Chemico-Biological Interactions 25 May 2024 395

Notopterol mitigates IL-1β-triggered pyroptosis by blocking NLRP3 inflammasome via the JAK2/NF-kB/hsa-miR-4282 route in osteoarthritis

Authors: Chen, Ko-Ta ^{a, 1}, Yeh, Chi-Tai ^{b, c, 1}, Yadav, Vijesh Kumar ^b, Pikatan, Narpati Wesa ^b, Fong, Iat-Hang ^b, Lee, Wei-Hwa ^d, Chiu, Yen-Shuo ^{e, f, g, h, ⁎}

Source: In Heliyon 30 March 2024 10(6)

Exosomal miR-21 determines lung-to-brain metastasis specificity through the DGKB/ERK axis within the tumor microenvironment

Authors: Tiong, Tung-Yu ^{a, b}, Chan, Mei-lin ^{c, d}, Wang, Chun-Hua ^{e, f}, Yadav, Vijesh Kumar ^g, Pikatan, Narpati Wesa ^h, Fong, Iat-Hang ^g, Yeh, Chi-Tai ^{g, i}, Kuo, Kuang-Tai ^{a, b}, Huang, Wen-Chien ^{c, d, ⁎}

Source: In Life Sciences 15 September 2023 329

Synergistic disruption of BTK and BCL-2 causes apoptosis while inducing ferroptosis in double-hit lymphoma

Authors: Setiawan, Syahru Agung, Liu, Winston Zhenhao, Weng, Pei‐Wei, Lee, Chia-Hwa, Yadav, Vijesh Kumar, Hardianti, Mardiah Suci, Yeh, Chi-Tai, Chao, Tsu-Yi

Source: In European Journal of Pharmacology 15 March 2023 943

Therapeutic targeting of hepatocellular carcinoma cells with antrocinol, a novel, dual-specificity, small-molecule inhibitor of the KRAS and ERK oncogenic signaling pathways

Authors: Hsu, Chia-Hung, Weng, Pei‐Wei, Chen, Ming-Yao, Yeh, Chi-Tai, Setiawan, Syahru Agung, Yadav, Vijesh Kumar, Wu, Alexander T.H., Tzeng, David T.W., Gong, Jian-Xian, Yang, Zhen, Tzeng, Yew-Min

Source: In Chemico-Biological Interactions 25 January 2023 370

Ovatodiolide and antrocin synergistically inhibit the stemness and metastatic potential of hepatocellular carcinoma via impairing ribosome biogenesis and modulating ERK/Akt-mTOR signaling axis

Authors: Chen, Ming-Yao, Hsu, Chia-Hung, Setiawan, Syahru Agung, Tzeng, David T.W., Ma, Hon-Ping, Ong, Jiann Ruey, Chu, Yi Cheng, Hsieh, Ming-Shou, Wu, Alexander T.H., Tzeng, Yew-Min, Yeh, Chi-Tai

Source: In Phytomedicine January 2023 108

Urokinase plasminogen activator induces epithelial-mesenchymal and metastasis of pancreatic cancer through plasmin/MMP14/TGF-β axis, which is inhibited by 4-acetyl-antroquinonol B treatment

Authors: Wu, Chung-Ze, Chu, Yi Cheng, Lai, Shiue-Wei, Hsieh, Ming-Shou, Yadav, Vijesh Kumar, Fong, Iat-Hang, Deng, Li, Huang, Chun-Chih, Tzeng, Yew-Min, Yeh, Chi-Tai, Chen, Jin-Shuen

Source: In Phytomedicine June 2022 100

Air pollution-regulated E-cadherin mediates contact inhibition of proliferation via the hippo signaling pathways in emphysema

Authors: Chang, Jer-Hwa, Lee, Yueh-Lun, Laiman, Vincent, Han, Chia-Li, Jheng, Yu-Teng, Lee, Kang-Yun, Yeh, Chi-Tai, Kuo, Han-Pin, Chung, Kian Fan, Heriyanto, Didik Setyo, Hsiao, Ta-Chih, Wu, Sheng-Ming, Ho, Shu-Chuan, Chuang, Kai-Jen, Chuang, Hsiao-Chi

Source: In Chemico-Biological Interactions 5 January 2022 351

The JAK inhibitor Tofacitinib inhibits structural damage in osteoarthritis by modulating JAK1/TNF-alpha/IL-6 signaling through Mir-149-5p

Authors: Chiu, Yen-Shuo, Bamodu, Oluwaseun Adebayo, Fong, Iat-Hang, Lee, Wei-Hwa, Lin, Chih-Cheng, Lu, Chen-Hsu, Yeh, Chi-Tai

Source: In Bone October 2021 151

Isoorientin inhibits epithelial-to-mesenchymal properties and cancer stem-cell-like features in oral squamous cell carcinoma by blocking Wnt/β-catenin/STAT3 axis

Authors: Liu, Shao-Cheng, Huang, Chin-Sheng, Huang, Chih-Ming, Hsieh, Ming-Shou, Huang, Mao-Suan, Fong, Iat-Hang, Yeh, Chi-Tai, Lin, Chih-Cheng

Source: In Toxicology and Applied Pharmacology 1 August 2021 424

Adipose-derived stem cell induced-tissue repair or wound healing is mediated by the concomitant upregulation of miR-21 and miR-29b expression and activation of the AKT signaling pathway

Authors: Liu, Shao-Cheng, Bamodu, Oluwaseun Adebayo, Kuo, Kuang-Tai, Fong, Iat-Hang, Lin, Chih-Cheng, Yeh, Chi-Tai, Chen, Shyi-Gen

Source: In Archives of Biochemistry and Biophysics 15 July 2021 705

Sphk1/S1P pathway promotes blood-brain barrier breakdown after intracerebral hemorrhage through inducing Nlrp3-mediated endothelial cell pyroptosis.

Authors: Feng, Mengzhao, An, Yuan, Qin, Qi, Fong, Iat-Hang, Zhang, Kaiyuan, Wang, Fang, Song, Dengpan, Li, Mengyuan, Yu, Min, Yeh, Chi-Tai, Chang, Junlei, Guo, Fuyou

Source: Cell Death & Disease; Dec2024, Vol. 15 Issue 12, p1-16, 16p

Effects of statins in patients with coronary artery spasm: A nationwide population‐based study.

Authors: Lee, Yu‐Ching, Hung, Ming‐Jui, Chen, Tien‐Hsing, Mao, Chun‐Tai, Yeh, Chi‐Tai, Kounis, Nicholas G., Chen, Ian Y., Hu, Patrick, Hung, Ming‐Yow

Source: CTS: Clinical & Translational Science; Nov2024, Vol. 17 Issue 11, p1-16, 16p

Subject Terms: MAJOR adverse cardiovascular events, HEMORRHAGIC stroke, PROPENSITY score matching, CORONARY artery disease, ISCHEMIC stroke

Ovatodiolide suppresses inflammatory response in BEAS-2B cells by regulating the CREB/AQP5 pathway, and sensitizes nasopharyngeal carcinoma cells to radiation therapy

Authors: Liu, Shao-Cheng, Huang, Chih-Ming, Chang, Yung-Lung, Bamodu, Oluwaseun Adebayo, Yeh, Chi-Tai, Wang, Hsing-Won, Lee, Fei-Peng, Lin, Chun-Shu

Source: In European Journal of Pharmacology 15 September 2019 859

Ovatodiolide inhibits the oncogenicity and cancer stem cell-like phenotype of glioblastoma cells, as well as potentiate the anticancer effect of temozolomide

Authors: Su, Yu-kai, Bamodu, Oluwaseun Adebayo, Tzeng, Yew-Min, Hsiao, Michael, Yeh, Chi-Tai, Lin, Chien-Min

Source: In Phytomedicine August 2019 61

Coronary Artery Spasm-Related Heart Failure Syndrome: Literature Review.

Authors: Hung, Ming-Jui¹ (AUTHOR) hmj1447@cgmh.org.tw, Yeh, Chi-Tai^2,3 (AUTHOR) ctyeh@s.tmu.edu.tw, Kounis, Nicholas G.⁴ (AUTHOR) ngkounis@otenet.gr, Koniari, Ioanna⁵ (AUTHOR) ioanna.koniari@lhch.nhs.uk, Hu, Patrick^6,7 (AUTHOR) patrick.hu@ucr.edu, Hung, Ming-Yow^8,9,10 (AUTHOR) myhung6@ms77.hinet.net

Source: International Journal of Molecular Sciences. Apr2023, Vol. 24 Issue 8, p7530. 35p.

Subject Terms: *KOUNIS syndrome, *CORONARY arteries, *HEART failure, *SYNDROMES, *ANGINA pectoris