A Genome-Scale RNA--Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington's Disease.

Authors: Miller, John P.¹, Yates, Bridget E.¹, Al-Ramahi, Ismael², Berman, Ari E.¹, Sanhueza, Mario², Kim, Eugene², de Haro, Maria², DeGiacomo, Francesco¹, Torcassi, Cameron¹, Holcomb, Jennifer¹, Gafni, Juliette¹, Mooney, Sean D.¹, Botas, Juan², Ellerby, Lisa M.¹ lellerby@buckinstitute.org, Hughes, Robert E.¹ rhughes@buckinstitute.org

Source: PLoS Genetics. Nov2012, Vol. 8 Issue 11, Special section p1-22. 22p. 1 Color Photograph, 1 Diagram, 2 Charts, 5 Graphs.

Subject Terms: *HUNTINGTON disease, *RNA interference, *GLUTAMIC acid, *PATHOLOGY, *DROSOPHILA, *ANIMAL models in research, *GENETICS

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