Deep Learning-Assisted Compound Bioactivity Estimation Framework

Authors: Yasmine Eid Mahmoud Yousef, Ayman El-Kilany, Farid Ali, Yassin M. Nissan, Ehab E. Hassanein

Source: Egyptian Informatics Journal, Vol 28, Iss , Pp 100558- (2024)

Subject Terms: Drug discovery, Deep learning, Regression, Auto-encoder, Classification, Electronic computers. Computer science, QA75.5-76.95

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S111086652400121X; https://doaj.org/toc/1110-8665

Access URL: https://doaj.org/article/c0dd1a4db37b4bbe8bc98b80c4b7c75c

New proapoptotic chemotherapeutic agents based on the quinolone-3-carboxamide scaffold acting by VEGFR-2 inhibition

Authors: Zeinab S. El-Fakharany, Yassin M. Nissan, Nada K. Sedky, Reem K. Arafa, Sahar M. Abou-Seri

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-22 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/fa84e6d1b71d42208b3a605f3cb0e6d6

Antimicrobial and anticancer activity of some novel fluorinated thiourea derivatives carrying sulfonamide moieties: synthesis, biological evaluation and molecular docking

Authors: Mostafa M. Ghorab, Mansour S. Alsaid, Mohamed S. A. El-Gaby, Mahmoud M. Elaasser, Yassin M. Nissan

Source: Chemistry Central Journal, Vol 11, Iss 1, Pp 1-14 (2017)

Subject Terms: Isothiocyanate, Sulfonamide, Fluorinated thiourea, Antimicrobial and anticancer activity, Chemistry, QD1-999

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13065-017-0258-4; https://doaj.org/toc/1752-153X

Access URL: https://doaj.org/article/1937e12809ab459fa143cd227757e66d

Design and Synthesis of New Quinoxaline Derivatives as Anticancer Agents and Apoptotic Inducers

Authors: Aliya M. S. El Newahie, Yassin M. Nissan, Nasser S. M. Ismail, Dalal A. Abou El Ella, Sohair M. Khojah, Khaled A.M. Abouzid

Source: Molecules, Vol 24, Iss 6, p 1175 (2019)

Subject Terms: quinoxaline, synthesis, anti-cancer activity, cell cycle, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/24/6/1175; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/57a8f786f960428fa7e2ea32e0f87e0f