Cost-Effectiveness of Artificial Intelligence-Enabled Electrocardiograms for Early Detection of Low Ejection Fraction: A Secondary Analysis of the Electrocardiogram Artificial Intelligence-Guided Screening for Low Ejection Fraction Trial

Authors: Thao, Viengneesee ^a, Zhu, Ye ^{a, b}, Tseng, Andrew S. ^c, Inselman, Jonathan W. ^a, Borah, Bijan J. ^a, McCoy, Rozalina G. ^e, Attia, Zachi I. ^c, Lopez-Jimenez, Francisco ^c, Pellikka, Patricia A. ^c, Rushlow, David R. ^d, Friedman, Paul A. ^c, Noseworthy, Peter A. ^c, Yao, Xiaoxi ^{a, c, ∗}

Source: In Mayo Clinic Proceedings: Digital Health December 2024 2(4):620-631

Assessing Artificial Intelligence Solution Effectiveness: The Role of Pragmatic Trials

Authors: Jin, Mauricio F. ^a, Noseworthy, Peter A. ^b, Yao, Xiaoxi ^{b, c, ∗}

Source: In Mayo Clinic Proceedings: Digital Health December 2024 2(4):499-510

Balloon guide catheters for endovascular thrombectomy in patients with acute ischaemic stroke due to large-vessel occlusion in China (PROTECT-MT): a multicentre, open-label, blinded-endpoint, randomised controlled trial

Authors: Feng, ZZ, Zou, C, Lv, N, Wang, CC, Duan, GL, Wu, YN, Yu, Y, Zheng, Q, Yin, HW, Zhang, MM, Wu, XF, Chen, L, Jiang, Y, Yang, WJ, Zhou, YH, Li, DM, Gan, LF, Yu, LJ, Jin, TY, Zhang, HJ, Xu, L, Han, N, Xu, XL, Qian, L, Li, Z, Wang, LJ, Zhang, GH, Jiang, W, Yi, TY, Wu, YM, Deng, JS, Wei, LM, Long, ZP, Lei, YB, Hao, JH, Zhang, ZY, Jia, ZY, Cao, YZ, Cao, J, Zhu, XC, Wang, SF, Luo, LL, Xu, Y, Lu, Y, Wang, H, Min, JL, Zhang, WB, Shi, MC, Tang, K, Yang, Y, Wu, J, Wang, M, Lu, HW, Su, DJ, Qi, DY, Zhu, DY, Sun, HY, Wang, XJ, Xu, SC, Xu, C, Qiao, HY, Guan, M, Wang, YP, Wang, QW, Liu, Y, Zhao, JX, Zhou, H, Yang, F, Huang, S, Hou, JK, Zhang, YX, Jia, ZC, Zhang, X, Yue, XC, Huang, CM, Zhao, B, Yu, T, Liu, Jianmin ^{*, *}, Zhou, Yu ^*, Zhang, Lei ^*, Li, Zifu ^*, Chen, Wenhuo ^*, Zhu, Yueqi, Yao, Xiaoxi, Zhang, Liyong, Liu, Shen, Peng, Ya, Wei, Ming, Zhang, Quanbin, Shu, Hansheng, Wang, Shouchun, Liu, Wenhua, Wan, Shu, Li, Tong, Fang, Yibin, Han, Hongxing, Zhang, Guang, Huang, Li'an, Wang, Feng, Cheng, Guangsen, Gao, Lianbo, Shi, Hongchao, Han, Jintao, Luo, Yun, Li, Shuai, Cai, Chuwei, Yin, Rong, Jin, Zhenglong, Shao, Chengwei, Tian, Bing, Zhang, Yongxin, Li, Qiang, Zhang, Yingying, Zhang, Ping, Li, Binben, Xing, Pengfei, Shen, Hongjian, Zhu, Xuan, Zhang, Xiaoxi, Hua, Weilong, Shen, Fang, Huyan, Meihua, Chen, Rundong, Zuo, Qiao, Huang, Qinghai, Xu, Yi, Deng, Benqiang, Zhao, Rui ^*, Goyal, Mayank ^*, Zhang, Yongwei ^*, Yang, Pengfei ^{*, *}

Source: In The Lancet 30 November-6 December 2024 404(10468):2165-2174

Evaluation of germicidal ultraviolet-C disinfection in a real-world outpatient health care environment

Authors: Challener, Douglas W., Tande, Aaron J., Koutras, Carolina, Wade, Richard L., McIntee, Maggie A., Strauss, David M., Yao, Xiaoxi, Chang, Yu- Hui, Berbari, Elie

Source: In AJIC: American Journal of Infection Control September 2024 52(9):1030-1034

Bailout intracranial angioplasty or stenting following thrombectomy for acute large vessel occlusion in China (ANGEL-REBOOT): a multicentre, open-label, blinded-endpoint, randomised controlled trial

Authors: Gao, Feng, Tong, Xu, Jia, Baixue, Wei, Ming, Pan, Yuesong, Yang, Ming, Sun, Dapeng, Nguyen, Thanh N, Ren, Zeguang, Demiraj, Francis, Yao, Xiaoxi, Xu, Chenghua, Yuan, Guangxiong, Wan, Yue, Tang, Jianjun, Wang, Jing, Jiang, Yuanfei, Wang, Chaobin, Luo, Xiang, Yang, Haihua, Shen, Ruile, Wu, Zhilin, Yuan, Zhengzhou, Wan, Dongjun, Hu, Wei, Liu, Yan, Jing, Ping, Wei, Liping, Zheng, Tuanyuan, Wu, Yingchun, Yang, Xinguang, Sun, Yaxuan, Wen, Changming, Chang, Mingze, Yin, Bo, Li, Di, Duan, Jixin, Sun, Dianjing, Guo, Zaiyu, Xu, Guodong, Wang, Guoqing, Wang, Liyu, Wang, Yang, Jia, Weihua, Ma, Gaoting, Huo, Xiaochuan, Mo, Dapeng, Ma, Ning, Liu, Liping, Zhao, Xingquan, Wang, Yilong, Fiehler, Jens, Wang, Yongjun ^**, Miao, Zhongrong ^*

Source: In The Lancet Neurology August 2024 23(8):797-806

Endovascular therapy in acute ischaemic stroke with large infarction with matched or mismatched clinical-radiological severities: a post-hoc analysis of the ANGEL-ASPECT trial

Authors: Wang, Yongjun, Wang, Yilong, Liu, Liping, Liebeskind, David S., Miao, Zhongrong, Ren, Zeguang, Pereira, Vitor Mendes, Ji, Xunming, Dong, Qiang, Xu, Anding, Liu, Xinfeng, Yang, Qingwu, Jing (Chair), Jing, Zhang, Zhe, Zhang, Yingkui, Wu, Wei, Sun, Dapeng, Qi, Zhongqi, Li, Shuo, Liu, Zhenqiang, Yu, Zequan, Zhang, Jingyu, Chen, Fangguang, Li, Kangyue, Zhang, Kai, Hu, Mingkai, Liu (Chair), Jianmin, Yao, Chen, Chen, Kangning, Fang (Chair), Kun, Song, Bo, Dong, Yi, Huo, Xiaochuan, Ma, Gaoting, Yuan, Guangxiong, Han, Hongxing, Chen, Wenhuo, Wei, Ming, Zhang, Jiangang, Zhou, Zhiming, Yao, Xiaoxi, Wang, Guoqing, Song, Weigen, Cai, Xueli, Nan, Guangxian, Li, Di, Wang, Yizhou, Ling, Wentong, Cai, Chuwei, Wen, Changming, Wang, En, Zhang, Liyong, Jiang, Changchun, Liu, Yajie, Liao, Geng, Chen, Xiaohui, Li, Tianxiao, Liu, Shudong, Li, Jinglun, Sun, Yaxuan, Xu, Na, Gao, Zong’en, Ju, Dongsheng, Song, Cunfeng, Xuan, Jinggang, Zhou, Feng, Shi, Qing, Luo, Jun, Liu, Yan, Guo, Zaiyu, Li, Tong, Zheng, Hongbo, Dai, Linzhi, Zhao, Junfeng, Gui, Liqiang, Geng, Xiaokun, Tang, Yufeng, Yin, Congguo, Yang, Hua, An, Ruiyang, Sun, Yuying, Wu, Yanan, Yu, Chunlai, Zheng, Shuangcheng, Pan, Yuesong, Jin, Aoming, Xiang, Xianglong, Wang, Mengxing, Yan, Hongyi, He, Yuanling, Li, Chunyang, Kong, Weixia, Chen, Yuhuan, Guo, Chenhao, Ji, Fengjie, Ji, Pengshan, Liu, Lei, Lu, Xinghua, Luo, Guangkuo, Wang, Nanjing, Zhang, Yu, Liu, Bo, Yang, Jian, Deng, Jingjing, Wang, Juan, Wang, Wanru, Yu, Hang, Cui, Le, Liu, Wenwen, Wang, Ziyong, Zhao, Xia, Zhou, Zhou, Yi-Chou Wang, Alvin, Zheng, Lina, Nie, Ximing, Liu, Xin, Duan, Wanying, Liu, Jingyi, Wei, Yufei, Wen, Miao, Yang, Zhonghua, Leung, Thomas W., Nguyen, Thanh N., Leng, Xinyi

Source: In eClinicalMedicine June 2024 72

Realtime Diagnosis from Electrocardiogram Artificial Intelligence-Guided Screening for Atrial Fibrillation with Long Follow-Up (REGAL): Rationale and design of a pragmatic, decentralized, randomized controlled trial

Authors: Yao, Xiaoxi, Attia, Zachi I., Behnken, Emma M., Hart, Melissa S., Inselman, Shealeigh A., Weber, Kayla C., Li, Fan, Stricker, Nikki H., Stricker, John L., Friedman, Paul A., Noseworthy, Peter A.

Source: In American Heart Journal January 2024 267:62-69

Physicians' perspectives on percutaneous left atrial appendage occlusion for patients with atrial fibrillation

Authors: Kir, Devika, Van Houten, Holly K., Walvatne, Kelli N., Behnken, Emma M., Alkhouli, Mohamad Adnan, Graff-Radford, Jonathan, Melduni, Rowlens M., Gersh, Bernard J., Friedman, Paul A., Shah, Nilay D., Noseworthy, Peter A., Yao, Xiaoxi

Source: In American Heart Journal December 2023 266:14-24

The Digitization and Decentralization of Clinical Trials

Authors: Harmon, David M., Noseworthy, Peter A., Yao, Xiaoxi

Source: In Mayo Clinic Proceedings October 2023 98(10):1568-1578

Clinical Trials Overview: From Explanatory to Pragmatic Clinical Trials

Authors: Le-Rademacher, Jennifer, Gunn, Heather, Yao, Xiaoxi, Schaid, Daniel J.

Source: In Mayo Clinic Proceedings August 2023 98(8):1241-1253

Screening for peripartum cardiomyopathies using artificial intelligence in Nigeria (SPEC-AI Nigeria): Clinical trial rationale and design

Authors: Adedinsewo, Demilade A., Morales-Lara, Andrea Carolina, Dugan, Jennifer, Garzon-Siatoya, Wendy T., Yao, Xiaoxi, Johnson, Patrick W., Douglass, Erika J., Attia, Zachi I., Phillips, Sabrina D., Yamani, Mohamad H., Tobah, Yvonne Butler, Rose, Carl H., Sharpe, Emily E., Lopez-Jimenez, Francisco, Friedman, Paul A., Noseworthy, Peter A., Carter, Rickey E.

Source: In American Heart Journal July 2023 261:64-74

Identifying treatment heterogeneity in atrial fibrillation using a novel causal machine learning method

Authors: Ngufor, Che, Yao, Xiaoxi, Inselman, Jonathan W., Ross, Joseph S., Dhruva, Sanket S., Graham, David J., Lee, Joo-Yeon, Siontis, Konstantinos C., Desai, Nihar R., Polley, Eric, Shah, Nilay D., Noseworthy, Peter A.

Source: In American Heart Journal June 2023 260:124-140

Clinician Adoption of an Artificial Intelligence Algorithm to Detect Left Ventricular Systolic Dysfunction in Primary Care.

Authors: Rushlow, David R., Croghan, Ivana T., Inselman, Jonathan W., Thacher, Tom D., Friedman, Paul A., Yao, Xiaoxi, Pellikka, Patricia A., Lopez-Jimenez, Francisco, Bernard, Matthew E., Barry, Barbara A., Attia, Itzhak Z., Misra, Artika, Foss, Randy M., Molling, Paul E., Rosas, Steven L., Noseworthy, Peter A.

Source: In Mayo Clinic Proceedings November 2022 97(11):2076-2085

Artificial intelligence-guided screening for atrial fibrillation using electrocardiogram during sinus rhythm: a prospective non-randomised interventional trial

Authors: Noseworthy, Peter A ^*, Attia, Zachi I, Behnken, Emma M, Giblon, Rachel E, Bews, Katherine A, Liu, Sijia, Gosse, Tara A, Linn, Zachery D, Deng, Yihong, Yin, Jun, Gersh, Bernard J, Graff-Radford, Jonathan, Rabinstein, Alejandro A, Siontis, Konstantinos C, Friedman, Paul A, Yao, Xiaoxi

Source: In The Lancet 8-14 October 2022 400(10359):1206-1212

Artificial Intelligence–Enabled Electrocardiogram for Atrial Fibrillation Identifies Cognitive Decline Risk and Cerebral Infarcts

Authors: Weil, Erika L., Noseworthy, Peter A., Lopez, Camden L., Rabinstein, Alejandro A., Friedman, Paul A., Attia, Zachi I., Yao, Xiaoxi, Siontis, Konstantinos C., Kremers, Walter K., Christopoulos, Georgios, Mielke, Michelle M., Vemuri, Prashanthi, Jack, Clifford R., Jr., Gersh, Bernard J., Machulda, Mary M., Knopman, David S., Petersen, Ronald C., Graff-Radford, Jonathan

Source: In Mayo Clinic Proceedings May 2022 97(5):871-880

Artificial Intelligence-Enabled ECG to Identify Silent Atrial Fibrillation in Embolic Stroke of Unknown Source

Authors: Rabinstein, Alejandro A., Yost, Micah D., Faust, Louis, Kashou, Anthony H., Latif, Omar S, Graff-Radford, Jonathan, Attia, Itzhak Zachi, Yao, Xiaoxi, Noseworthy, Peter A., Friedman, Paul A.

Source: In Journal of Stroke and Cerebrovascular Diseases September 2021 30(9)

Batch enrollment for an artificial intelligence-guided intervention to lower neurologic events in patients with undiagnosed atrial fibrillation: rationale and design of a digital clinical trial

Authors: Yao, Xiaoxi, Attia, Zachi I., Behnken, Emma M., Walvatne, Kelli, Giblon, Rachel E., Liu, Sijia, Siontis, Konstantinos C., Gersh, Bernard J., Graff-Radford, Jonathan, Rabinstein, Alejandro A., Friedman, Paul A., Noseworthy, Peter A.

Source: In American Heart Journal September 2021 239:73-79

Cost Effectiveness of an Electrocardiographic Deep Learning Algorithm to Detect Asymptomatic Left Ventricular Dysfunction

Authors: Tseng, Andrew S., Thao, Viengneesee, Borah, Bijan J., Attia, Itzhak Zachi, Medina Inojosa, Jose, Kapa, Suraj, Carter, Rickey E., Friedman, Paul A., Lopez-Jimenez, Francisco, Yao, Xiaoxi, Noseworthy, Peter A.

Source: In Mayo Clinic Proceedings July 2021 96(7):1835-1844

Long-Term Clinical Outcomes of Underdosed Direct Oral Anticoagulants in Patients with Atrial Fibrillation and Atrial Flutter

Authors: Ashraf, Hasan, Agasthi, Pradyumna, Shanbhag, Anusha, Mehta, Ramila A., Rattanawong, Pattara, Allam, Mohamed, Pujari, Sai Harika, Mookadam, Farouk, Freeman, William K., Srivathsan, Komandoor, Sorajja, Dan, Shen, Win-Kuang, Noseworthy, Peter A., Yang, Eric H., Masry, Hicham Z. El, Yao, Xiaoxi, Mulpuru, Siva K., Beohar, Nirat, Holmes, David R., Jr, Arsanjani, Reza

Source: In The American Journal of Medicine June 2021 134(6):788-796

Renal Outcomes in Patients with Systolic Heart Failure Treated With Sacubitril-Valsartan or Angiotensin Converting Enzyme Inhibitor/Angiotensin Receptor Blocker

Authors: Tan, Nicholas Y., Deng, Yihong, Yao, Xiaoxi, Sangaralingham, Lindsey R., Shah, Nilay D., Rule, Andrew D., Burnett, John C., Jr., Dunlay, Shannon M., Sangaralingham, S. Jeson

Source: In Mayo Clinic Proceedings: Innovations, Quality & Outcomes April 2021 5(2):286-297