Evidence of premature lymphocyte aging in people with low anti-spike antibody levels after BNT162b2 vaccination

Authors: Huang, Yapei, Shin, Juliana E., Xu, Alexander M., Yao, Changfu, Joung, Sandy, Wu, Min, Zhang, Ruan, Shin, Bongha, Foley, Joslyn, Mahov, Simeon B., Modes, Matthew E., Ebinger, Joseph E., Driver, Matthew, Braun, Jonathan G., Jefferies, Caroline A., Parimon, Tanyalak, Hayes, Chelsea, Sobhani, Kimia, Merchant, Akil, Gharib, Sina A., Jordan, Stanley C., Cheng, Susan, Goodridge, Helen S., Chen, Peter

Source: In iScience 21 October 2022 25(10)

Categorization of lung mesenchymal cells in development and fibrosis

Authors: Liu, Xue, Rowan, Simon C., Liang, Jiurong, Yao, Changfu, Huang, Guanling, Deng, Nan, Xie, Ting, Wu, Di, Wang, Yizhou, Burman, Ankita, Parimon, Tanyalak, Borok, Zea, Chen, Peter, Parks, William C., Hogaboam, Cory M., Weigt, S. Samuel, Belperio, John, Stripp, Barry R., Noble, Paul W., Jiang, Dianhua

Source: In iScience 25 June 2021 24(6)

SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery

Authors: Mulay, Apoorva, Konda, Bindu, Garcia, Gustavo, Jr., Yao, Changfu, Beil, Stephen, Villalba, Jaquelyn M., Koziol, Colin, Sen, Chandani, Purkayastha, Arunima, Kolls, Jay. K., Pociask, Derek A., Pessina, Patrizia, de Aja, Julio Sainz, Garcia-de-Alba, Carolina, Kim, Carla F., Gomperts, Brigitte, Arumugaswami, Vaithilingaraja, Stripp, Barry R.

Source: In Cell Reports 4 May 2021 35(5)

Cell-Type-Specific Immune Dysregulation in Severely Ill COVID-19 Patients

Authors: Yao, Changfu, Bora, Stephanie A., Parimon, Tanyalak, Zaman, Tanzira, Friedman, Oren A., Palatinus, Joseph A., Surapaneni, Nirmala S., Matusov, Yuri P., Cerro Chiang, Giuliana, Kassar, Alexander G., Patel, Nayan, Green, Chelsi E.R., Aziz, Adam W., Suri, Harshpreet, Suda, Jo, Lopez, Andres A., Martins, Gislâine A., Stripp, Barry R., Gharib, Sina A., Goodridge, Helen S., Chen, Peter

Source: In Cell Reports 5 January 2021 34(1)

Senescence of Alveolar Type 2 Cells Drives Progressive Pulmonary Fibrosis

Authors: Yao, Changfu, Guan, Xiangrong, Carraro, Gianni, Parimon, Tanyalak, Liu, Xue, Huang, Guanling, Mulay, Apoorva, Soukiasian, Harmik J., David, Gregory, Weigt, Stephen S.

Source: American journal of respiratory and critical care medicine. 203(6):707-717

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN628007091&indx=1&recIds=ETOCRN628007091

Cell competition drives bronchiolization and pulmonary fibrosis.

Authors: Warren, Rachel, Klinkhammer, Kylie, Lyu, Handeng, Knopp, Joseph, Yuan, Tingting, Yao, Changfu, Stripp, Barry, De Langhe, Stijn P.

Source: Nature Communications; 12/5/2024, Vol. 15 Issue 1, p1-17, 17p

Subject Terms: IDIOPATHIC pulmonary fibrosis, STEM cells, WNT genes, MYC oncogenes, GENE expression

FGF10-FGFR2B Signaling Generates Basal Cells and Drives Alveolar Epithelial Regeneration by Bronchial Epithelial Stem Cells after Lung Injury

Authors: Yuan, Tingting, Volckaert, Thomas, Redente, Elizabeth F., Hopkins, Seantel, Klinkhammer, Kylie, Wasnick, Roxana, Chao, Cho-Ming, Yuan, Jie, Zhang, Jin-San, Yao, Changfu, Majka, Susan, Stripp, Barry R., Günther, Andreas, Riches, David W.H., Bellusci, Saverio, Thannickal, Victor J., De Langhe, Stijn P.

Source: In Stem Cell Reports 14 May 2019 12(5):1041-1055

Single-Cell Reconstruction of Human Basal Cell Diversity in Normal and Idiopathic Pulmonary Fibrosis Lungs

Authors: Carraro, Gianni, Mulay, Apoorva, Yao, Changfu, Mizuno, Takako, Konda, Bindu, Petrov, Martin, Lafkas, Daniel, Arron, Joe R., Hogaboam, Cory M., Chen, Peter

Source: American journal of respiratory and critical care medicine. 202(11):1540-1550

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN625479847&indx=1&recIds=ETOCRN625479847

An aberrant immune–epithelial progenitor niche drives viral lung sequelae.

Authors: Narasimhan, Harish, Cheon, In Su, Qian, Wei, Hu, Sheng’en Shawn, Parimon, Tanyalak, Li, Chaofan, Goplen, Nick, Wu, Yue, Wei, Xiaoqin, Son, Young Min, Fink, Elizabeth, de Almeida Santos, Gislane, Tang, Jinyi, Yao, Changfu, Muehling, Lyndsey, Canderan, Glenda, Kadl, Alexandra, Cannon, Abigail, Young, Samuel, Hannan, Riley

Source: Nature; Oct2024, Vol. 634 Issue 8035, p961-969, 9p

Transcriptomics Analysis Identifies the Decline in the Alveolar Type II Stem Cell Niche in Aged Human Lungs.

Authors: Liu, Xue, Zhang, Xuexi, Yao, Changfu, Liang, Jiurong, Noble, Paul W., Jiang, Dianhua

Source: American Journal of Respiratory Cell & Molecular Biology; Aug2024, Vol. 71 Issue 2, p229-241, 13p

Subject Terms: STEM cell niches, LUNGS, TRANSCRIPTOMES, TRANSCRIPTION factors, CELLULAR aging

Single-Cell Deconvolution of Fibroblast Heterogeneity in Mouse Pulmonary Fibrosis

Authors: Xie, Ting, Wang, Yizhou, Deng, Nan, Huang, Guanling, Taghavifar, Forough, Geng, Yan, Liu, Ningshan, Kulur, Vrishika, Yao, Changfu, Chen, Peter, Liu, Zhengqiu, Stripp, Barry, Tang, Jie, Liang, Jiurong, Noble, Paul W., Jiang, Dianhua

Source: In Cell Reports 27 March 2018 22(13):3625-3640

STK11 is required for the normal program of ciliated cell differentiation in airways

Authors: Chu, Qiqi, Yao, Changfu, Qi, Xiangbing, Stripp, Barry, Tang, Nan

Source: Cell discovery. 5(1):1-16

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185361860.0x000001&indx=1&recIds=ETOCvdc_100185361860.0x000001

Interstitial Macrophages Mediate Efferocytosis of Alveolar Epithelium during Influenza Infection.

Authors: Zuttion, Marilia Sanchez Santos Rizzo, Parimon, Tanyalak, Yao, Changfu, Stripp, Barry R., Wang, Ying, Soto, Christopher M., Ortega, Zackary, Li, Xiao, Janssen, William J., Chen, Peter

Source: American Journal of Respiratory Cell & Molecular Biology; Mar2024, Vol. 70 Issue 3, p159-164, 6p

Subject Terms: ALVEOLAR macrophages, INFLUENZA, LUNGS, EPITHELIAL cells, MACROPHAGES, EPITHELIUM

Rare SOX2+ Airway Progenitor Cells Generate KRT5+ Cells that Repopulate Damaged Alveolar Parenchyma following Influenza Virus Infection

Authors: Ray, Samriddha, Chiba, Norika, Yao, Changfu, Guan, Xiangrong, McConnell, Alicia M., Brockway, Brian, Que, Loretta, McQualter, Jonathan L., Stripp, Barry R.

Source: Stem cell reports. 7(5):817-825

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100062940732.0x000001&indx=1&recIds=ETOCvdc_100062940732.0x000001

P53 Regulates Progenitor Cell Quiescence and Differentiation in the Airway

Authors: McConnell, Alicia M., Yao, Changfu, Yeckes, Alyson R., Wang, Yizhou, Selvaggio, Anna S., Tang, Jie, Kirsch, David G., Stripp, Barry R.

Source: Cell reports. 17(9):2173-2182

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100050592003.0x000001&indx=1&recIds=ETOCvdc_100050592003.0x000001

Domain Requirements of the JIL-1 Tandem Kinase for Histone H3 Serine 10 Phosphorylation and Chromatin Remodeling in Vivo

Authors: Li, Yeran, Cai, Weili, Wang, Chao, Yao, Changfu, Bao, Xiaomin, Deng, Huai, Girton, Jack, Johansen, Jørgen, Johansen, Kristen M.

Source: In Journal of Biological Chemistry 5 July 2013 288(27):19441-19449

Epithelial plasticity and innate immune activation promote lung tissue remodeling following respiratory viral infection.

Authors: Beppu, Andrew K., Zhao, Juanjuan, Yao, Changfu, Carraro, Gianni, Israely, Edo, Coelho, Anna Lucia, Drake, Katherine, Hogaboam, Cory M., Parks, William C., Kolls, Jay K., Stripp, Barry R.

Source: Nature Communications; 9/19/2023, Vol. 14 Issue 1, p1-16, 16p

Subject Terms: VIRUS diseases, LUNGS, RESPIRATORY infections, TISSUE remodeling, FATE mapping (Genetics), LUNG diseases

HER2 drives lung fibrosis by activating a metastatic cancer signature in invasive lung fibroblasts

Authors: Liu, Xue, Geng, Yan, Liang, Jiurong, Coelho, Ana Lucia, Yao, Changfu, Deng, Nan, Wang, Yizhou, Dai, Kristy, Huang, Guanling, Xie, Ting

Source: Journal of experimental medicine. 219(10):e20220126-e20220126

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN630369732&indx=1&recIds=ETOCRN630369732

Chromator is required for proper microtubule spindle formation and mitosis in Drosophila

Authors: Ding, Yun, Yao, Changfu, Lince-Faria, Mariana, Rath, Uttama, Cai, Weili, Maiato, Helder, Girton, Jack, Johansen, Kristen M., Johansen, Jørgen

Source: In Developmental Biology 2009 334(1):253-263

Evidence for a role of spindle matrix formation in cell cycle progression by antibody perturbation.

Authors: Yao, Changfu¹, Wang, Chao¹, Li, Yeran¹, Zavortink, Michael¹, Archambault, Vincent², Girton, Jack¹, Johansen, Kristen M.¹ kristen@iastate.edu, Johansen, Jørgen¹ jorgen@iastate.edu

Source: PLoS ONE. 11/28/2018, Vol. 13 Issue 11, p1-23. 23p.

Subject Terms: *EXTRACELLULAR matrix proteins, *DROSOPHILA physiology, *CELL cycle, *IMMUNOGLOBULINS, *MICROTUBULES