Therapeutic targeting de novo purine biosynthesis driven by β-catenin-dependent PPAT upregulation in hepatoblastoma

Authors: Ming Ding, Chunshuang Ma, Yanyan Lin, Houshun Fang, Yan Xu, Shuxuan Wang, Yao Chen, Jiquan Zhou, Hongxiang Gao, Yuhua Shan, Liyuan Yang, Huiying Sun, Yabin Tang, Xiaoyu Wu, Liang Zhu, Liang Zheng, Yehuda G. Assaraf, Bin-Bing S. Zhou, Song Gu, Hui Li

Source: Cell Death and Disease, Vol 16, Iss 1, Pp 1-14 (2025)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/efb40728d3a44722b20fc4d0da43e1e2

Biological and genetic characterization of a newly established human primary multidrug-resistant distal cholangiocarcinoma cell line, CBC3T-6

Authors: Mingzhen Bai, Ruoshui Wang, Chongfei Huang, Ruyang Zhong, Ningzu Jiang, Wenkang Fu, Ningning Mi, Long Gao, Yuyao Jin, Haidong Ma, Jie Cao, Haiying Yu, Qiang Jing, Chao Zhang, Ping Yue, Yong Zhang, Yanyan Lin, Hengwei Zhang, Wenbo Meng

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Subject Terms: Distal cholangiocarcinoma, Cell line, Multidrug resistance, KRAS mutations, TP53 mutations, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/d768550e8ec847dc99ac103f084fabbe

Characteristics of gut microbiota and metabolites in extrahepatic cholangiocarcinoma and their prognostic value for resectable lesions

Authors: Cheng Ye, Bo Zhang, Yanyan Lin, Fangfang Han, Huaqing Shi, Chunlu Dong, Wence Zhou

Source: Frontiers in Cellular and Infection Microbiology, Vol 15 (2025)

Subject Terms: extrahepatic cholangiocarcinoma, gut microbiota, metabolites, postoperative prognosis, predictive value, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2025.1523863/full; https://doaj.org/toc/2235-2988

Access URL: https://doaj.org/article/1904638aa1b94a4d89360be1e1752856

Beyond ribosomal function: RPS6 deficiency suppresses cholangiocarcinoma cell growth by disrupting alternative splicing

Authors: Wenkang Fu, Yanyan Lin, Mingzhen Bai, Jia Yao, Chongfei Huang, Long Gao, Ningning Mi, Haidong Ma, Liang Tian, Ping Yue, Yong Zhang, Jinduo zhang, Yanxian Ren, Liyun Ding, Lunzhi Dai, Joseph W. Leung, Jinqiu Yuan, Wenhua Zhang, Wenbo Meng

Source: Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 3931-3948 (2024)

Subject Terms: Cholangiocarcinoma, Ribosomal protein S6, Alternative splicing, p53, Minichromosome maintenance complex component 7, Vivo morpholino, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211383524002582; https://doaj.org/toc/2211-3835

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N-acetyltransferase 10 affects the proliferation of intrahepatic cholangiocarcinoma and M2-type polarization of macrophages by regulating C-C motif chemokine ligand 2

Authors: Teng Cai, Jianye Dai, Yanyan Lin, Zhongtian Bai, Jingdong Li, Wenbo Meng

Source: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)

Subject Terms: NAT10, Intrahepatic cholangiocarcinoma, CCL2, Berberine, Macrophage, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/438c5993590048f683814889caf9bf5e

eHSP90α in front-line therapy in EGFR exon 19 deletion and 21 Leu858Arg mutations in advanced lung adenocarcinoma

Authors: Yingzhen Bian, Haizhou Liu, Jinglei Huang, Zhaorong Feng, Yanyan Lin, Jilin Li, Litu Zhang

Source: BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)

Subject Terms: eHSP90α, Exon 19 deletion, Exon 21 Leu858Arg, Lung adenocarcinoma, Biomarker, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/dee9d7a29eb4463e965a0cdfde0ad8f1

Early prediction of acute gallstone pancreatitis severity: a novel machine learning model based on CT features and open access online prediction platform

Authors: Yuhu Ma, Ping Yue, Jinduo Zhang, Jinqiu Yuan, Zhaoqing Liu, Zixian Chen, Hengwei Zhang, Chao Zhang, Yong Zhang, Chunlu Dong, Yanyan Lin, Yatao Liu, Shuyan Li, Wenbo Meng

Source: Annals of Medicine, Vol 56, Iss 1 (2024)

Subject Terms: Gallstone pancreatitis, CT features, radiomics, random forest, prediction, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/0785-3890; https://doaj.org/toc/1365-2060

Access URL: https://doaj.org/article/c5f2f7ff1b7c42da98d8e3c0da4a6d5b

Design and synthesis of quorum-sensing agonist for improving biofilm formation and the application of Acidithiobacillus thiooxidans in bioleaching

Authors: Deping Tang, Yanpeng Xi, Wentao Song, Mengjiao Li, Yali Liu, Yanyan Lin, Ran Zhang, Aihong Mao

Source: Frontiers in Microbiology, Vol 15 (2024)

Subject Terms: quorum sensing agonist, Acidithiobacillus thiooxidans, biofilm, adhesion, bioleaching, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2024.1465633/full; https://doaj.org/toc/1664-302X

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Management of left atrial myxoma in pregnant women: a case series

Authors: Yanli Liu, Haiping Wang, Huanlei Huang, Fengzhen Han, Jian Zhuang, Yanqiu Ou, Yanyan Lin, Weina Zhang

Source: Journal of Cardiothoracic Surgery, Vol 19, Iss 1, Pp 1-6 (2024)

Subject Terms: Cardiac myxoma, Pregnancy, Cardiopulmonary bypass, Totally endoscopic minimally invasive cardiac surgery, Outcome, Surgery, RD1-811, Anesthesiology, RD78.3-87.3

File Description: electronic resource

Relation: https://doaj.org/toc/1749-8090

Access URL: https://doaj.org/article/95b07c4812234bb7827aafa26b1ed4b6

Design of the distribution of iron oxide (Fe3O4) nano-particle drug in realistic cholangiocarcinoma model and the simulation of temperature increase during magnetic induction hyperthermia

Authors: Yawen Lu, Chongfei Huang, WenKang Fu, Long Gao, Ningning Mi, Haidong Ma, Mingzhen Bai, Zhili Xia, Xianzhuo Zhang, Liang Tian, Jinyu Zhao, Ningzu Jiang, Leiqing Wang, Ruyang Zhong, Chao Zhang, Yeying Wang, YanYan Lin, Ping Yue, Wenbo Meng

Source: Pharmacological Research, Vol 207, Iss , Pp 107333- (2024)

Subject Terms: cholangiocarcinoma, magnetic hyperthermia therapy, magnetic nanoparticles, 3D models, Finite Element Analysis, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1043661824002780; https://doaj.org/toc/1096-1186

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Dietary patterns, genetic predisposition, and risk of cholelithiasis: a large-scale prospective cohort study

Authors: Kecheng Jin, Ningning Mi, Wangping He, Ruyang Zhong, Boru Jin, Zhen Liu, Chunlu Dong, Yanyan Lin, Ping Yue, Bin Xia, Qiangsheng He, Jinqiu Yuan, Wenbo Meng

Source: Frontiers in Nutrition, Vol 11 (2024)

Subject Terms: dietary patterns, genetic risk, cholelithiasis, UK Biobank, gene-diet interactions, dietary intervention, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnut.2024.1469789/full; https://doaj.org/toc/2296-861X

Access URL: https://doaj.org/article/58a4d0bdd400425db04a76b7b35f8f35

The hidden hurdles of clinical clerkship: unraveling the types and distribution of professionalism dilemmas among South Korean medical students

Authors: Ye Ji Kang, Yanyan Lin, Jaehee Rho, Jungjoon Ihm, Do-Hwan Kim

Source: BMC Medical Education, Vol 24, Iss 1, Pp 1-13 (2024)

Subject Terms: Clerkship, Medical professionalism dilemmas, Medical students, Nun-chi, Student-doctor, Special aspects of education, LC8-6691, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1472-6920

Access URL: https://doaj.org/article/e759e14004d34719b4ffd519488ec843

Regular use of paracetamol and risk of liver cancer: a prospective cohort study

Authors: Liang Tian, Ningning Mi, Leiqing Wang, Chongfei Huang, Wenkang Fu, Mingzhen Bai, Long Gao, Haidong Ma, Chao Zhang, Yawen Lu, Jinyu Zhao, Xianzhuo Zhang, Ningzu Jiang, Yanyan Lin, Ping Yue, Bin Xia, Qiangsheng He, Jinqiu Yuan, Wenbo Meng

Source: BMC Cancer, Vol 24, Iss 1, Pp 1-8 (2024)

Subject Terms: Liver cancer, Paracetamol, Prospective cohort study, UK Biobank, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/bacf09ca74a3419ca81cee37762be386

Diphylleia Grayi-Inspired Intelligent Temperature-Responsive Transparent Nanofiber Membranes

Authors: Cengceng Zhao, Gaohui Liu, Yanyan Lin, Xueqin Li, Na Meng, Xianfeng Wang, Shaoju Fu, Jianyong Yu, Bin Ding

Source: Nano-Micro Letters, Vol 16, Iss 1, Pp 1-12 (2024)

Subject Terms: Biomimetic, Transparent, Nanofibrous membrane, Temperature response, Phase change materials, Technology

File Description: electronic resource

Relation: https://doaj.org/toc/2311-6706; https://doaj.org/toc/2150-5551

Access URL: https://doaj.org/article/92835fc4258b4dbba8d391710808579d

Transcriptome Analysis Reveals the Mechanism of Y0-C10-HSL on Biofilm Formation and Motility of Pseudomonas aeruginosa

Authors: Deping Tang, Yali Liu, Huihui Yao, Yanyan Lin, Yanpeng Xi, Mengjiao Li, Aihong Mao

Source: Pharmaceuticals, Vol 17, Iss 12, p 1719 (2024)

Subject Terms: P. aeruginosa, biofilm, transcriptome, quorum sensing inhibitor, C. elegans, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/17/12/1719; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/72d7a0ce89e14d59be62bd4b0c2bbd31

Correlation analysis between BRAFV600E mutation and ultrasonic and clinical features of papillary thyroid cancer

Authors: Jiahao Wen, Haizhou Liu, Yanyan Lin, Zixuan Liang, Lili Wei, Qi Zeng, Shanshan Wei, Litu Zhang, Weiping Yang

Source: Heliyon, Vol 10, Iss 9, Pp e29955- (2024)

Subject Terms: Papillary thyroid cancer, BRAF, Ultrasonic features, Nomogram, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024059863; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/b378773876cb468baecbbc786e9536a5

Integrated analysis of scRNA-seq and bulk RNA-seq reveals that GPRC5A is an important prognostic gene in pancreatic cancer and is associated with B-cell Infiltration in pancreatic cancer

Authors: Chunlu Dong, Haidong Ma, Ningning Mi, Wenkang Fu, Jianfeng Yi, Long Gao, Haiping Wang, Yanxian Ren, Yanyan Lin, Fangfang Han, Zhou Chen, Wence Zhou

Source: Frontiers in Oncology, Vol 14 (2024)

Subject Terms: pancreatic cancer, single-cell, immune infiltration, B cell, Gprc5a, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1283164/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/02d2a27bf311406786a610bb0911e908

Metabolic characteristics and pathogenesis of precocious puberty in girls: the role of perfluorinated compounds

Authors: Jinxia Wu, Jing Chen, Rong Huang, Hongwei Zhu, Lin Che, Yanyan Lin, Yajie Chang, Guiping Shen, Jianghua Feng

Source: BMC Medicine, Vol 21, Iss 1, Pp 1-18 (2023)

Subject Terms: Premature thelarche, Central precocious puberty, Specific biomarkers, Metabolic network, Perfluorinated compounds, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/e0c69627a5d44fb4a742d990c309ab64

Identification of a novel bile marker clusterin and a public online prediction platform based on deep learning for cholangiocarcinoma

Authors: Long Gao, Yanyan Lin, Ping Yue, Shuyan Li, Yong Zhang, Ningning Mi, Mingzhen Bai, Wenkang Fu, Zhili Xia, Ningzu Jiang, Jie Cao, Man Yang, Yanni Ma, Fanxiang Zhang, Chao Zhang, Joseph W. Leung, Shun He, Jinqiu Yuan, Wenbo Meng, Xun Li

Source: BMC Medicine, Vol 21, Iss 1, Pp 1-15 (2023)

Subject Terms: Cholangiocarcinoma, Clusterin, Deep learning, Diagnostic biomarker, Proteomics, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/37a8a2223d054d4998630db313ece8d4

The association between family adaptability and adolescent depression: the chain mediating role of social support and self-efficacy

Authors: Yanyan Lin, Guangyunxian Jia, Zirong Zhao, Meng Li, Guanghai Cao

Source: Frontiers in Psychology, Vol 15 (2024)

Subject Terms: family adaptability, social support, self-efficacy, depression, adolescents, Psychology, BF1-990

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fpsyg.2024.1308804/full; https://doaj.org/toc/1664-1078

Access URL: https://doaj.org/article/b3075b24c64d40d5a6884e47c5d5b77f