Characterization of the trehalase function of Haemonchus contortus and its immunomodulatory effect on host PBMCs

Authors: Wen, Zhaohai ^{a, b}, Yan, Shuping ^{a, b}, Amujilata ^b, Feng, Jiajun ^b, Chen, Cheng ^b, Xu, Yongde ^b, Lu, Mingmin ^b, Xu, Lixin ^b, Song, Xiaokai ^b, Li, Xiangrui ^b, Yan, Ruofeng ^{b, ⁎}

Source: In International Journal of Biological Macromolecules May 2025 309 Part 4

Vaccination with formulations targeting Eimeria maxima and Clostridium perfringens conferred comprehensive protection using a dual-infection challenge model of necrotic enteritis

Authors: Zhang, Qingzheng ^a, Yuan, Yue ^a, Pu, Xianglin ^a, Xu, Lixin ^a, Song, Xiaokai ^a, Yan, Ruofeng ^a, Li, Xiangrui ^a, Li, Charles ^b, Yuan, Cheng ^{c, ⁎}, Lu, Mingmin ^{a, b, ⁎⁎}

Source: In Poultry Science February 2025 104(2)

Protective efficacy of Eimeria maxima EmLPL and EmTregIM-1 against homologous challenge in chickens

Authors: Xiang, Quanjia, Wan, Yun, Pu, Xianglin, Lu, Mingmin, Xu, Lixin, Yan, Ruofeng, Li, Xiangrui, Song, Xiaokai

Source: In Poultry Science July 2024 103(7)

Identification and characterization of the receptors of a microneme adhesive repeat domain of Eimeria maxima microneme protein 3 in chicken intestine epithelial cells

Authors: Zhang, Yang, Lu, Mingmin, Huang, Jianmei, Tian, Xiaowei, Liang, Meng, Wang, Mingyue, Song, Xiaokai, Xu, Lixin, Yan, Ruofeng, Li, Xiangrui

Source: In Poultry Science April 2024 103(4)

IFN-γ inhibitory molecules derived from Eimeria maxima inhibit IL-12 secretion by modulating MAPK pathways in chicken macrophages

Authors: Chen, Chen, Chen, Yufeng, Lu, Mingmin, Xu, Lixin, Yan, Ruofeng, Li, Xiangrui, Song, Xiaokai

Source: In Poultry Science February 2024 103(2)

Inhibitory effect of Eimeria maxima IFN-γ inhibitory molecules on the immune function of T cell subsets in chickens

Authors: Pu, Xianglin, Pan, Yangdong, Xiang, Quanjia, Lu, Mingmin, Xu, Lixin, Yan, Ruofeng, Li, Xiangrui, Song, Xiaokai

Source: In Poultry Science December 2023 102(12)

Eimeria tenella 14-kDa phosphohistidine phosphatase stimulates maturation of chicken dendritic cells and mediates DC-induced T cell priming in a Th1 cytokine interface

Authors: Lakho, Shakeel Ahmed, Haseeb, Muhammad, Huang, Jianmei, Hasan, Muhammad Waqqas, Khand, Faiz Muhammad, Leghari, Ambreen, Aleem, Muhammad Tahir, Ali, Hyder, Song, XiaoKai, Xu, Lixin, Yan, RuoFeng, Li, XiangRui

Source: In Research in Veterinary Science 20 December 2022 152:61-71

Hepatocellular carcinoma-associated antigen 59 and ADP-ribosylation factor 1 with poly (lactic-co-glycolic acid): A promising candidate as nanovaccine against haemonchosis

Authors: Wang, QiangQiang, Muhammad, Tahir Aleem, Muhammad, Waqqas Hasan, Muhammad, Ali Memon, Muhammad, Haseeb, Yan, RuoFeng, Xu, LiXin, Song, XiaoKai, Li, XiangRui

Source: In Microbial Pathogenesis July 2022 168

Histone deacetylase SIR2 in Toxoplasma gondii modulates functions of murine macrophages in vitro and protects mice against acute toxoplasmosis in vivo

Authors: Yu, ZhengQing, Chen, SiYing, Aleem, MuhammadTahir, He, SuHui, Yang, Yang, Zhou, TianYuan, Liu, JunLong, Luo, JianXun, Yan, RuoFeng, Xu, LiXin, Song, XiaoKai, Li, XiangRui

Source: In Microbial Pathogenesis May 2021 154

Poly (D, L-lactide-co-glycolide) delivery system improve the protective efficacy of recombinant antigen TA4 against Eimeria tenella infection

Authors: Huang, Jianmei, Chen, Siying, Zhou, Zhouyang, Sun, Xiaoting, Haseeb, Muhammad, Lakho, Shakeel Ahmed, Zhang, Yang, Liu, Jiabin, Shah, Muhammad Ali A., Song, Xiaokai, Xu, Lixin, Yan, Ruofeng, Li, Xiangrui

Source: In Poultry Science May 2021 100(5)

Haemonchus contortus hepatocellular carcinoma-associated antigen 59 with poly (lactic-co-glycolic acid): A promising nanovaccine candidate against Haemonchus contortus infection

Authors: Wang, QiangQiang, Muhammad, Tahir Aleem, Muhammad, Waqqas Hasan, Muhammad, Ali Memon, Muhammad, Haseeb, Yan, RuoFeng, Xu, LiXin, Song, XiaoKai, Li, XiangRui ^*

Source: In Veterinary Parasitology April 2021 292

Enzymes involved in trehalose-chitin synthesis in Haemonchus contortus could be vaccine candidates for goats.

Authors: Wen, Zhaohai, Amu, Jilata, Aimulajiang, Kalibixiati, Feng, Jiajun, Chen, Cheng, Xu, Yongde, Lu, Mingmin, Xu, Lixin, Song, Xiaokai, Li, Xiangrui, Yan, Ruofeng

Source: Parasites & Vectors; 2/20/2025, Vol. 18 Issue 1, p1-13, 13p

Subject Terms: HAEMONCHUS contortus, SUBCUTANEOUS injections, RECOMBINANT proteins, IMMUNOGLOBULIN G, MEDICAL sciences

Modulatory functions of recombinant electron transfer flavoprotein α subunit protein from Haemonchus contortus on goat immune cells in vitro

Authors: Wang, Yujian, Ehsan, Muhammad, Wang, Shuai, Tian, Xiaowei, Yan, RuoFeng, Song, XiaoKai, Xu, LiXin, Li, XiangRui ^*

Source: In Veterinary Parasitology December 2020 288

Characterization of a phosphotyrosyl phosphatase activator homologue of the parasitic nematode Haemonchus contortus and its immunomodulatory effect on goat peripheral blood mononuclear cells in vitro

Authors: Wang, Yujian, Wang, Wenjuan, Ehsan, Muhammad, Zhang, Yang, Yan, RuoFeng, Song, XiaoKai, Xu, LiXin, Zhang, Xichen, Li, XiangRui

Source: In International Journal for Parasitology December 2020 50(14):1157-1166

In vitro effects of 5 recombinant antigens of Eimeria maxima on maturation, differentiation, and immunogenic functions of dendritic cells derived from chicken spleen

Authors: Haseeb, Muhammad, Lakho, Shakeel Ahmed, Huang, Jianmei, Hasan, Muhammad Waqqas, Ali-ul-Husnain Naqvi, Muhammad, Zhou, Zhouyang, Yan, Ruofeng, Xu, Lixin, Song, Xiaokai, Li, Xiangrui

Source: In Poultry Science November 2020 99(11):5331-5343

HcFAR, a functional inhibitor of goat TGF-β1 identified from excretory and secretory products of Haemonchus contortus

Authors: Bu, Yongqian, Cao, Man, Tian, Xiaowei, Lu, Mingmin, Li, Junjie, Mao, Dingyi, Yu, Lin, Memon, Muhammad Ali, Li, Charles, Xu, Lixin, Song, Xiaokai, Yan, Ruofeng, Li, Xiangrui ^*

Source: In Veterinary Parasitology October 2020 286

Recombinant ubiquitin-conjugating enzyme of Eimeria maxima induces immunogenic maturation in chicken splenic-derived dendritic cells and drives Th1 polarization in-vitro

Authors: Lakho, Shakeel Ahmed, Haseeb, Muhammad, Huang, Jianmei, Hasan, Muhammad Waqqas, Naqvi, Muhammad Ali-ul-Husnain, Zhou, Zhouyang, Song, XiaoKai, Yan, RuoFeng, Xu, Lixin, Li, XiangRui

Source: In Microbial Pathogenesis June 2020 143

Haemonchus contortus transthyretin domain - containing protein (HcTTR): A promising vaccine candidate against Haemonchus contortus infection

Authors: Tian, Xiaowei, Lu, Mingmin, Jia, Caiwen, Bu, Yongqian, Aimulajiang, Kalibixiati, Zhang, Yang, Li, Charles, Yan, Ruofeng, Xu, Lixin, Song, Xiaokai, Li, Xiangrui ^*

Source: In Veterinary Parasitology March 2020 279

Immunodiagnostic potential of recombinant tropomyosin during prepatent Haemonchus contortus infection in goat

Authors: Naqvi, Muhammad Ali-ul-Husnain, Jamil, Tahseen, Naqvi, Sana Zahra, Memon, Muhammad Ali, Aimulajiang, Kalibixiati, Aleem, Muhammad Tahir, Ehsan, Muhammad, Xu, Lixin, Song, Xiaokai, Li, Xiangrui, Yan, Ruofeng

Source: In Research in Veterinary Science February 2020 128:197-204

Nanoparticle containing recombinant excretory/secretory-24 protein of Haemonchus contortus enhanced the cellular immune responses in mice.

Authors: Hasan, Muhammad Waqqas, Haseeb, Muhammad, Gadahi, Javaid Ali, Ehsan, Muhammad, Wang, Qiangqiang, Lakho, Shakeel Ahmed, Haider, Ali, Aleem, Muhammad Tahir, Aimulajiang, Kalibixiati, Lu, Mingmin, Xu, Lixin, Song, Xiaokai, Li, Xiangrui, Yan, Ruofeng

Source: Frontiers in Veterinary Science; 2024, p1-13, 13p

Subject Terms: HAEMONCHUS contortus, VACCINE effectiveness, PHENOTYPIC plasticity, SCANNING electron microscopes, T cells