Polycationic phosphorous dendrimer potentiates multiple antibiotics against drug-resistant mycobacterial pathogens

Authors: Imran, Mohmmad, Singh, Shriya, Ahmad, Mohammad Naiyaz, Malik, Pradip, Mukhopadhyay, Atri, Yadav, Karan Singh, Gupta, Umesh D., Mugale, Madhav N., Mitra, Kalyan, Srivastava, Kishore K., Chopra, Sidharth, Mignani, Serge, Apartsin, Evgeny, Majoral, Jean-Pierre, Dasgupta, Arunava

Source: In Biomedicine & Pharmacotherapy April 2024 173

Cooperative STAT3-NFkB signaling modulates mitochondrial dysfunction and metabolic profiling in hepatocellular carcinoma

Authors: Ishteyaque, Sharmeen, Singh, Gurvinder, Yadav, Karan Singh, Verma, Smriti, Sharma, Rakesh Kumar, Sen, Sumati, Srivastava, Anurag Kumar, Mitra, Kalyan, Lahiri, Amit, Bawankule, Dnyaneshwar U., Rath, Srikanta Kumar, Kumar, Dinesh, Mugale, Madhav Nilakanth

Source: In Metabolism March 2024 152

Imperatorin ameliorates kidney injury in diabetic mice by regulating the TGF-β/Smad2/3 signaling axis, epithelial-to-mesenchymal transition, and renal inflammation

Authors: Kundu, Sourav, Ghosh, Ankana, Yadav, Karan Singh, Mugale, Madhav Nilakanth, Sahu, Bidya Dhar

Source: In European Journal of Pharmacology 15 January 2024 963

CYP2E1 triggered GRP78/ATF6/CHOP signaling axis inhibit apoptosis and promotes progression of hepatocellular carcinoma

Authors: Ishteyaque, Sharmeen, Yadav, Karan Singh, Verma, Smriti, Washimkar, Kaveri R., Mugale, Madhav Nilakanth

Source: In Archives of Biochemistry and Biophysics 1 September 2023 745

Chitosan/HPMC-based mucoadhesive film co-loaded with fluconazole and ofloxacin for management of polymicrobial keratitis

Authors: Sanap, Sachin Nashik, Bisen, Amol Chhatrapati, Kedar, Ashwini, Yadav, Karan Singh, Krishna, Atul, Akhir, Abdul, Chopra, Sidharth, Mugale, Madhav Nilakanth, Bhatta, Rabi Sankar

Source: In International Journal of Biological Macromolecules 1 December 2022 222 Part B:2785-2795

QbD based antifungal drug-loaded ophthalmic liposomal formulation for the management of fungal keratitis: In vitro, ex vivo and in vivo pharmacokinetic studies

Authors: Sanap, Sachin Nashik, Bisen, Amol Chhatrapati, Mishra, Anjali, Biswas, Arpon, Agrawal, Sristi, Yadav, Karan Singh, Krishna, Atul, Chopra, Sidharth, Mugale, Madhav Nilakanth, Bhatta, Rabi Sankar

Source: In Journal of Drug Delivery Science and Technology August 2022 74

4-HIL mitigates type-2 diabetic complications through inhibiting inflammation and Nrf2 mediated oxidative stress in rats

Authors: Singh, Rupali, Yadav, Karan Singh, Prajapati, Ramanand, Sharma, Sharad, Rath, Srikanta Kumar, Narender, Tadigoppula, Mugale, Madhav Nilakanth

Source: In Phytomedicine Plus February 2022 2(1)

Solanum nigrum Toxicity and Its Neuroprotective Effect Against Retinal Ganglion Cell Death Through Modulation of Extracellular Matrix in a Glaucoma Rat Model.

Authors: Yadav, Karan Singh^1,2 (AUTHOR), Bisen, Amol Chhatrapati^2,3 (AUTHOR), Ishteyaque, Sharmeen^1,2 (AUTHOR), Sharma, Isha¹ (AUTHOR), Verma, Smriti^1,2 (AUTHOR), Sanap, Sachin Nashik^2,3 (AUTHOR), Verma, Shobhit^1,2 (AUTHOR), Washimkar, Kaveri R.^1,2 (AUTHOR), Kumar, Akhilesh¹ (AUTHOR), Tripathi, Vineeta^2,4 (AUTHOR), Bhatta, Rabi Sankar^2,3 (AUTHOR), Mugale, Madhav Nilakanth^1,2 (AUTHOR) madhav.mugale@cdri.res.in

Source: Journal of Ocular Pharmacology & Therapeutics. Jun2024, Vol. 40 Issue 5, p309-324. 16p.

Subject Terms: *RETINAL ganglion cells, *LABORATORY rats, *SOLANUM nigrum, *EXTRACELLULAR matrix, *LIQUID chromatography-mass spectrometry

Pharmaceutical Emulsions: A Viable Approach for Ocular Drug Delivery.

Authors: Bisen, Amol Chhatrapati, Srivastava, Saurabh, Mishra, Anjali, Sanap, Sachin Nashik, Biswas, Arpon, Choudhury, Abhijit Deb, Dubey, Ayush, Gupta, Neeraj Mohan, Yadav, Karan Singh, Mugale, Madhav Nilakanth, Bhatta, Rabi Sankar

Source: Journal of Ocular Pharmacology & Therapeutics; Jun2024, Vol. 40 Issue 5, p261-280, 20p

Subject Terms: OPHTHALMIC drugs, EMULSIONS, DRUG development

Redoxisome and diabetic retinopathy: Pathophysiology and therapeutic interventions

Authors: Sharma, Isha, Yadav, Karan Singh, Mugale, Madhav Nilakanth

Source: Pharmacological research. 182

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187743993.0x000001&indx=1&recIds=ETOCvdc_100187743993.0x000001

Corrigendum to “Cooperative STAT3-NFkB signaling modulates mitochondrial dysfunction and metabolic profiling in hepatocellular carcinoma” [Metabolism, Volume 152, March 2024, 155771]

Authors: Ishteyaque, Sharmeen, Singh, Gurvinder, Yadav, Karan Singh, Verma, Smriti, Sharma, Rakesh Kumar, Sen, Sumati, Srivastav, Anurag Kumar, Mitr, Kalyan, Lahiri, Amit, Bawankule, Dnyaneshwar U., Rath, Srikanta Kumar, Kumar, Dinesh, Mugale, Madhav Nilakanth

Source: In Metabolism April 2024 153

Assessment of antidiabetic effect of 4-HIL in type 2 diabetic and healthy Sprague Dawley rats.

Authors: Singh, Pragati, Ishteyaque, Sharmeen, Prajapati, Ramanand, Yadav, Karan Singh, Singh, Rupali, Kumar, Akhilesh, Sharma, Sharad, Narender, Tadigoppula, Mugale, Madhav Nilakanth

Source: Human & Experimental Toxicology; Jan-Dec2022, Vol. 41, p1-11, 11p

Subject Terms: BIOLOGICAL models, IN vitro studies, PANCREAS, IN vivo studies, BODY weight, ANIMAL experimentation, BLOOD sugar monitoring, HYPOGLYCEMIC agents, ISOLEUCINE, AMINOGLYCOSIDES, DIABETES, TYPE 2 diabetes, TREATMENT effectiveness, RATS, COMPARATIVE studies, SEEDS, DESCRIPTIVE statistics, TOXICITY testing, PLANT extracts, CELL lines, GLUCOSE tolerance tests, INSULIN resistance, PHARMACODYNAMICS

Hypohidrotic ectodermal dysplasia presenting as aural and nasal myiasis

Authors: Bhat K., Vikram, Ramya, B., Yadav, Karan Singh

Source: In International Journal of Pediatric Otorhinolaryngology Extra 2009 4(3):114-117

QbD based antifungal drug-loaded ophthalmic liposomal formulation for the management of fungal keratitis: In vitro, ex vivoand in vivopharmacokinetic studies

Authors: Sanap, Sachin Nashik, Bisen, Amol Chhatrapati, Mishra, Anjali, Biswas, Arpon, Agrawal, Sristi, Yadav, Karan Singh, Krishna, Atul, Chopra, Sidharth, Mugale, Madhav Nilakanth, Bhatta, Rabi Sankar

Source: Journal of Drug Delivery Science and Technology; August 2022, Vol. 74 Issue: 1

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