USP14 promotes tryptophan metabolism and immune suppression by stabilizing IDO1 in colorectal cancer

Authors: Dongni Shi, Xianqiu Wu, Yunting Jian, Junye Wang, Chengmei Huang, Shuang Mo, Yue Li, Fengtian Li, Chao Zhang, Dongsheng Zhang, Huizhong Zhang, Huilin Huang, Xin Chen, Y. Alan Wang, Chuyong Lin, Guozhen Liu, Libing Song, Wenting Liao

Source: Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/da0e7849fcb34a24976064852f9e4e8c

Prediction of biomarkers and therapeutic combinations for anti-PD-1 immunotherapy using the global gene network association

Authors: Chia-Chin Wu, Y. Alan Wang, J. Andrew Livingston, Jianhua Zhang, P. Andrew Futreal

Source: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/3bdbdf71cb3845a18e523fbc02456486

Telomere dysfunction activates YAP1 to drive tissue inflammation

Authors: Deepavali Chakravarti, Baoli Hu, Xizeng Mao, Asif Rashid, Jiexi Li, Jun Li, Wen-ting Liao, Elizabeth M. Whitley, Prasenjit Dey, Pingping Hou, Kyle A. LaBella, Andrew Chang, Guocan Wang, Denise J. Spring, Pingna Deng, Di Zhao, Xin Liang, Zhengdao Lan, Yiyun Lin, Sharmistha Sarkar, Christopher Terranova, Yonathan Lissanu Deribe, Sarah E. Blutt, Pablo Okhuysen, Jianhua Zhang, Eduardo Vilar, Ole Haagen Nielsen, Andrew Dupont, Mamoun Younes, Kalyani R. Patel, Noah F. Shroyer, Kunal Rai, Mary K. Estes, Y. Alan Wang, Alison A. Bertuch, Ronald A. DePinho

Source: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/b5a35bee98a746039f8bae5793248657

Effective combinatorial immunotherapy for penile squamous cell carcinoma

Authors: Tianhe Huang, Xi Cheng, Jad Chahoud, Ahmed Sarhan, Pheroze Tamboli, Priya Rao, Ming Guo, Ganiraju Manyam, Li Zhang, Yu Xiang, Leng Han, Xiaoying Shang, Pingna Deng, Yanting Luo, Xuemin Lu, Shan Feng, Magaly Martinez Ferrer, Y. Alan Wang, Ronald A. DePinho, Curtis A. Pettaway, Xin Lu

Source: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/a75e587ee5244319a4b94f79be2430fb

Telomere dysfunction induces metabolic and mitochondrial compromise.

Authors: Sahin, Ergün, Colla, Simona, Liesa, Marc, Moslehi, Javid, Müller, Florian L., Guo, Mira, Cooper, Marcus, Kotton, Darrell, Fabian, Attila J., Walkey, Carl, Maser, Richard S., Tonon, Giovanni, Foerster, Friedrich, Robert Xiong, Y. Alan Wang, Shukla, Sachet A., Jaskelioff, Mariela, Martin, Eric S., Heffernan, Timothy P., Protopopov, Alexei

Source: Nature. 2/17/2011, Vol. 470 Issue 7334, p359-365. 7p. 5 Graphs.

Subjects: MITOCHONDRIAL DNA, REACTIVE oxygen species, TELOMERES, GROWTH factors, GLUCONEOGENESIS, DNA damage, STEM cells, APOPTOSIS

ATM is activated by mitotic stress and suppresses centrosome amplification in primary but not in tumor cells.

Authors: Kate Shen, Yaolin Wang, S.C. Brooks, Avraham Raz, Y. Alan Wang

Source: Journal of Cellular Biochemistry; Dec2006, Vol. 99 Issue 5, p1267-1274, 8p

Stochastic cancer progression driven by non‐clonal chromosome aberrations.

Authors: Henry H. Q. Heng, Joshua B. Stevens, Gou Liu, Steven W. Bremer, Karen J. Ye, Prem‐Veer Reddy, Gen Sheng Wu, Y. Alan Wang, Michael A. Tainsky, Christine J. Ye

Source: Journal of Cellular Physiology; Aug2006, Vol. 208 Issue 2, p461-472, 12p

Subject Terms: CHROMOSOME abnormalities, STOCHASTIC analysis, CELL nuclei, CANCER research

Induction of murine leukemia and lymphoma by dominant negative retinoic acid receptor α.

Authors: Y. Alan Wang, Kate Shen, Yasumasa Ishida, Yaolin Wang, Akira Kakizuka, S.C. Brooks

Source: Molecular Carcinogenesis; Dec2005, Vol. 44 Issue 4, p252-261, 0p

Retinoic acid signaling is required for proper morphogenesis of mammary gland.

Authors: Y. Alan Wang, Kate Shen, Yaolin Wang, S.C. Brooks

Source: Developmental Dynamics; Dec2005, Vol. 234 Issue 4, p892-899, 0p

Effects of an Indolocarbazole-Derived CDK4 Inhibitor on Breast Cancer Cells

Authors: Yuan Sun, Ying-xia Li, Hai-jun Wu, Si-hung Wu, Y. Alan Wang, Dian-zhong Luo, D. Joshua Liao

Source: Journal of Cancer, Vol 2, Iss 1, Pp 36-51 (2011)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.jcancer.org/v02p0036.htm; https://doaj.org/toc/1837-9664

Access URL: https://doaj.org/article/b8b715f68dd344cebdea1b253bc5af2b