Polymeric immunogel prevents tumor recurrence and metastasis by dual activation of innate and adaptive immunity

Authors: Guanyu Jin, Hao Liu, Zi Mei, Qionghua Jin, Sheng Ma, Lanqing Wang, Yuanzhen Su, Letian Lv, Zijuan Wang, Huicong Zhou, Mingqiang Li, Zehuan Huang, Xuesi Chen, Shixian Lv

Source: Bioactive Materials, Vol 45, Iss , Pp 102-114 (2025)

Subject Terms: Polymeric drug carriers, Polymeric hydrogels, Biodegradable polymers, Controlled drug release, Tumor recurrence and metastasis, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X24004924; https://doaj.org/toc/2452-199X

Access URL: https://doaj.org/article/8d02ceedd9fb45a299b1fb2b07541356

Mannan-decorated STING-activating vaccine carrier for spatial coordinative stimulating antigen-specific immune responses

Authors: Liping Liu, Jiayu Zhao, Zichao Huang, Yudi Xu, Hongyu Chen, Ruirui Qiao, Wantong Song, Zhaohui Tang, Thomas P. Davis, Xuesi Chen

Source: Fundamental Research, Vol 5, Iss 1, Pp 183-191 (2025)

Subject Terms: Cancer immunotherapy, Cancer vaccine, Nanotechnology, Drug delivery, Biopolymer, Science (General), Q1-390

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S266732582300122X; https://doaj.org/toc/2667-3258

Access URL: https://doaj.org/article/32afaaa1dfa14ab4a88eed8b780412da

Minimally Invasive Injectable Gel for Local Immunotherapy of Liver and Gastric Cancer

Authors: Xinghui Si, Guofeng Ji, Sheng Ma, Zichao Huang, Taiyuan Liu, Zhiyuan Shi, Yu Zhang, Jia Li, Wantong Song, Xuesi Chen

Source: Advanced Science, Vol 11, Iss 38, Pp n/a-n/a (2024)

Subject Terms: cancer immunotherapy, gastric cancer, hydrogels, liver cancer, minimally invasive injection, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/8c53c6c75b1d4946a722d306c93ee26e

Sustainable, Recyclable, and Bench-Stable Catalytic System for Synthesis of Poly(ester‑b‑carbonate)

Authors: Yifan Jia, Bokun Li, Yifei Sun, Chenyang Hu, Xiang Li, Shunjie Liu, Xianhong Wang, Xuan Pang, Xuesi Chen

Source: Chem & Bio Engineering, Vol 1, Iss 6, Pp 559-567 (2024)

Subject Terms: Chemical engineering, TP155-156, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://doaj.org/toc/2836-967X

Access URL: https://doaj.org/article/a67faadb084a454ab02ce945ad55cd7a

Light‐Assisted 3D‐Printed Hydrogels for Antibacterial Applications

Authors: Liwen Zhang, Naufal Kabir Ahamed Nasar, Xumin Huang, Chenyang Hu, Xuan Pang, Xuesi Chen, Ruirui Qiao, Thomas Paul Davis

Source: Small Science, Vol 4, Iss 8, Pp n/a-n/a (2024)

Subject Terms: 3D printing, antibacterial and tissue engineering, hydrogel, Materials of engineering and construction. Mechanics of materials, TA401-492

File Description: electronic resource

Relation: https://doaj.org/toc/2688-4046

Access URL: https://doaj.org/article/1f5c1e1f1bb7422e9e142c179cc8e7f8

Ultra-durable cell-free bioactive hydrogel with fast shape memory and on-demand drug release for cartilage regeneration

Authors: Yuxuan Yang, Xiaodan Zhao, Shuang Wang, Yanfeng Zhang, Aiming Yang, Yilong Cheng, Xuesi Chen

Source: Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/3ce000e10897485ba706e48bf8cbcb58

Gene-guided OX40L anchoring to tumor cells for synergetic tumor 'self-killing' immunotherapy

Authors: Lin Lin, Yingying Hu, Zhaopei Guo, Jie Chen, Pingjie Sun, Huayu Tian, Xuesi Chen

Source: Bioactive Materials, Vol 25, Iss , Pp 689-700 (2023)

Subject Terms: OX40L anchoring to tumor cell membrane, Gene engineering, Tumor immunotherapy, Anti-PD therapy, Tumor relapse and metastasis, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X22003073; https://doaj.org/toc/2452-199X

Access URL: https://doaj.org/article/d7e24fd3b4e2431ab75ce8a0fa3cc534

Ring-finger protein 5 attenuates oxygen-glucose deprivation and reperfusion-induced mitochondrial dysfunction and inflammation in cardiomyocytes by inhibiting the S100A8/MYD88/NF-κB axis

Authors: Xuesi Chen, Yingjie Wu, Yingchun Bao

Source: Chinese Journal of Physiology, Vol 66, Iss 4, Pp 228-238 (2023)

Subject Terms: heart failure, inflammation, mitochondrial dysfunction, ring-finger protein 5, s100a8/myd88/nf-κb axis, Physiology, QP1-981

File Description: electronic resource

Relation: http://www.cjphysiology.org/article.asp?issn=0304-4920;year=2023;volume=66;issue=4;spage=228;epage=238;aulast=Chen; https://doaj.org/toc/0304-4920; https://doaj.org/toc/2666-0059

Access URL: https://doaj.org/article/fb687ad6cdf7407ebefd1cf939b94956

Fabrication of Antifouling/Antimicrobial Polysulfonium‐Coated Surface Against Biofilms and Water Bacterial Contamination

Authors: Xutao Ma, Min Lin, Jing Sun, Xuesi Chen

Source: Advanced NanoBiomed Research, Vol 3, Iss 7, Pp n/a-n/a (2023)

Subject Terms: antibacterial, antifouling, biofilms, coatings, polysulfoniums, water bacterial contamination, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/2699-9307

Access URL: https://doaj.org/article/eb7ecfded6df4bfcb8da499733afd2f7

Predicting potential biomarkers and immune infiltration characteristics in heart failure

Authors: Xuesi Chen, Qijun Zhang, Qin Zhang

Source: Mathematical Biosciences and Engineering, Vol 19, Iss 9, Pp 8671-8688 (2022)

Subject Terms: immune infiltrate, heart failure, machine learning, lasso, cibersort, svm-rfe, Biotechnology, TP248.13-248.65, Mathematics, QA1-939

File Description: electronic resource

Relation: https://doaj.org/toc/1551-0018

Access URL: https://doaj.org/article/f94749b85cfb4c2f9135a056dc9f484e

Instructive cartilage regeneration modalities with advanced therapeutic implantations under abnormal conditions

Authors: Zhonghan Wang, Hanxiang Le, Yanbing Wang, He Liu, Zuhao Li, Xiaoyu Yang, Chenyu Wang, Jianxun Ding, Xuesi Chen

Source: Bioactive Materials, Vol 11, Iss , Pp 317-338 (2022)

Subject Terms: Cartilage lesion, Pathological microenvironment, Synergistic effect, Tissue engineering, Cartilage regeneration, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X21004540; https://doaj.org/toc/2452-199X

Access URL: https://doaj.org/article/0f70be2105894145a4567fdbd36cc660

Biofunctionalized composite scaffold to potentiate osteoconduction, angiogenesis, and favorable metabolic microenvironment for osteonecrosis therapy

Authors: Tongtong Zhu, Mengyang Jiang, Mingran Zhang, Liguo Cui, Xiaoyu Yang, Xukai Wang, Guangyao Liu, Jianxun Ding, Xuesi Chen

Source: Bioactive Materials, Vol 9, Iss , Pp 446-460 (2022)

Subject Terms: Biofunctionalized scaffold, Osteoconduction, Angiogenesis, Favorable metabolic microenvironment, Osteonecrosis therapy, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X21003686; https://doaj.org/toc/2452-199X

Access URL: https://doaj.org/article/f28cf238a0774e8d804479d68b3836dd

Combining mannose receptor mediated nanovaccines and gene regulated PD-L1 blockade for boosting cancer immunotherapy

Authors: Jie Chen, Huapan Fang, Yingying Hu, Jiayan Wu, Sijia Zhang, Yuanji Feng, Lin Lin, Huayu Tian, Xuesi Chen

Source: Bioactive Materials, Vol 7, Iss , Pp 167-180 (2022)

Subject Terms: Gene delivery, PD-L1 blockade, Targeted vaccine, Nanovaccines, Tumor immunotherapy, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X21002565; https://doaj.org/toc/2452-199X

Access URL: https://doaj.org/article/bae696f74ad649fba7a21f95f196d33f

Combination of epigenetic regulation with gene therapy-mediated immune checkpoint blockade induces anti-tumour effects and immune response in vivo

Authors: Huapan Fang, Zhaopei Guo, Jie Chen, Lin Lin, Yingying Hu, Yanhui Li, Huayu Tian, Xuesi Chen

Source: Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/88a68866c470414a9fb6c60275bc712b

Reactive oxygen species activated by mitochondria-specific camptothecin prodrug for enhanced chemotherapy

Authors: Zhaopei Guo, Zian Wang, Ruifeng Liang, Huayu Tian, Xuesi Chen, Meiwan Chen

Source: Biomolecules & Biomedicine, Vol 22, Iss 6 (2022)

Subject Terms: Camptothecin prodrug, reactive oxygen species, antitumor therapy, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.bjbms.org/ojs/index.php/bjbms/article/view/7194; https://doaj.org/toc/2831-0896; https://doaj.org/toc/2831-090X

Access URL: https://doaj.org/article/f7b8cad552b34e1d814313e7cc55d505

Bioactive Materials Promote Wound Healing through Modulation of Cell Behaviors

Authors: Ruotao Li, Kai Liu, Xu Huang, Di Li, Jianxun Ding, Bin Liu, Xuesi Chen

Source: Advanced Science, Vol 9, Iss 10, Pp n/a-n/a (2022)

Subject Terms: bioactive material, cell behavior, wound microenvironment, wound healing, regenerative medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/22cbd3c4a2b443d99f038e455699c3bb

3D Printed Personalized Nerve Guide Conduits for Precision Repair of Peripheral Nerve Defects

Authors: Kai Liu, Lesan Yan, Ruotao Li, Zhiming Song, Jianxun Ding, Bin Liu, Xuesi Chen

Source: Advanced Science, Vol 9, Iss 12, Pp n/a-n/a (2022)

Subject Terms: peripheral nerve repair, personalized nerve guide conduit, precision tissue regeneration, three‐dimensional printing, tissue engineering, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/f278e813e89d44d286a6cd9f5ca1055b

Construction and validation of steroid-induced rabbit osteonecrosis model

Authors: Tongtong Zhu, Mengyang Jiang, Mingran Zhang, Liguo Cui, Xiaoyu Yang, Xukai Wang, Guangyao Liu, Jianxun Ding, Xuesi Chen

Source: MethodsX, Vol 9, Iss , Pp 101713- (2022)

Subject Terms: Steroid-induced rabbit osteonecrosis model, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2215016122000942; https://doaj.org/toc/2215-0161

Access URL: https://doaj.org/article/b7431deb1c6c458f81b86f2b83e42863

Injectable Polypeptide Hydrogel Depots Containing Dual Immune Checkpoint Inhibitors and Doxorubicin for Improved Tumor Immunotherapy and Post-Surgical Tumor Treatment

Authors: Zhixiong Chen, Yan Rong, Junfeng Ding, Xueliang Cheng, Xuesi Chen, Chaoliang He

Source: Pharmaceutics, Vol 15, Iss 2, p 428 (2023)

Subject Terms: hydrogel, combination therapy, immunotherapy, polypeptide, ICB therapy, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/2/428; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/ed4a2ec7fd224e01bfe7dc85a0bf37ab

Advanced biosafety materials for prevention and theranostics of biosafety issues

Authors: Jianxun Ding, Haihua Xiao, Xuesi Chen

Source: Biosafety and Health, Vol 4, Iss 2, Pp 59-60 (2022)

Subject Terms: Infectious and parasitic diseases, RC109-216, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590053622000337; https://doaj.org/toc/2590-0536

Access URL: https://doaj.org/article/717dc2c7129045d49bdffa9e0590faef