Phase 2 study of serplulimab with the bevacizumab biosimilar HLX04 in the first-line treatment of advanced hepatocellular carcinoma

Authors: Zhenggang Ren, Guoliang Shao, Jie Shen, Li Zhang, Xu Zhu, Weijia Fang, Guoping Sun, Yuxian Bai, Jianbing Wu, Lianxin Liu, Yuan Yuan, Jingdong Zhang, Zhen Li, Ling Zhang, Tao Yin, Jincai Wu, Xiaoli Hou, Haoyu Yu, Jing Li, Qingyu Wang, Jun Zhu, Jia Fan, the Serplulimab-HCC Investigators

Source: Cancer Immunology, Immunotherapy, Vol 74, Iss 2, Pp 1-12 (2025)

Subject Terms: Serplulimab, HLX04, Anti-PD-1, Bevacizumab biosimilar, Advanced hepatocellular carcinoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1432-0851

Access URL: https://doaj.org/article/8a8026f6fa5644ddb4018e00329803a1

Visible-Light-Driven Carboxylative 1,2-Difunctionalization of CC Bonds with Tetrabutylammonium Oxalate

Authors: Sai Wang, Pei Xu, Zhi-Tao Liu, Yi-Qin Liu, Hao-Qiang Jiang, Tian-Zi Hao, Hui-Xian Jiang, Hui Xu, Xu-Dong Cao, Dong Guo, Xu Zhu

Source: ACS Central Science, Vol 11, Iss 1, Pp 46-56 (2024)

Subject Terms: Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2374-7951

Access URL: https://doaj.org/article/848375ca293746cbb4d29b69f496cba6

Study on the therapeutic potential of induced neural stem cells for Alzheimer's disease in mice

Authors: Qiongqiong Ji, Yuanhao Lv, Bei Hu, Yue Su, Imran Ibrahim Shaikh, Xu Zhu

Source: Biological Research, Vol 57, Iss 1, Pp 1-12 (2024)

Subject Terms: Alzheimer’s disease (AD), Mouse embryonic fibroblasts (MEFs), Induced neural stem cells (iNSCs), Sox2, Valproic acid (VPA), Transplantation treatment, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/0717-6287

Access URL: https://doaj.org/article/e743445e14984db2959a6fccc10b43e5

Associations between exposure to volatile organic compounds with obesity in adults

Authors: Runmiao Wu, Lei Jia, Xu Zhu, Gongchang Guan, Junkui Wang, Rutai Hui, Meijuan Ma, Zhao Zhao, Hui Pang, Ling Zhu

Source: Human Nutrition & Metabolism, Vol 39, Iss , Pp 200296- (2025)

Subject Terms: VOCs, Obesity, NHANES, Qgcomp, Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666149724000586; https://doaj.org/toc/2666-1497

Access URL: https://doaj.org/article/332fec53162f4493a2e40f7a74b49c57

Inverse Relationship Between Serum Carotenoid Levels and Cardiovascular‐Kidney‐Metabolic Syndrome Among the General Adult Population

Authors: Mengli Chen, Shuyue Cai, Qinfeng Jia, Yifang Suo, Yuan Tang, Yanping Shi, Xu Zhu, Haifeng Zhang

Source: Journal of Diabetes, Vol 17, Iss 2, Pp n/a-n/a (2025)

Subject Terms: cardiovascular disease, carotenoids, kidney disease, metabolic syndrome, NHANES, WQS, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://doaj.org/toc/1753-0393; https://doaj.org/toc/1753-0407

Access URL: https://doaj.org/article/9dcdbe25c54b49599da0963d3dc3e8b3

Increasing Health Burdens Driven by Global Trade Induced Air Pollution

Authors: Ruifei Li, Yu Luo, Xu Zhu, Jin Zhang, Pei Hua, Zhenyu Wang, Wenyu Yang, Qiuwen Chen, Hui Li

Source: Earth's Future, Vol 13, Iss 1, Pp n/a-n/a (2025)

Subject Terms: air pollution, health burdens, consumption and income‐based, socioeconomic drivers, international trade, Environmental sciences, GE1-350, Ecology, QH540-549.5

File Description: electronic resource

Relation: https://doaj.org/toc/2328-4277

Access URL: https://doaj.org/article/c16c17427fbc44bba39ab23a993a4cdb

Association between HALP (hemoglobin, albumin, lymphocyte, and platelet) score and poor outcomes in acute ischemic stroke patients with type 2 diabetes mellitus: a study from the Third China National Stroke Registry

Authors: Xu Zhu, Yijun Zhang, Anxin Wang, Xiaoli Zhang, Guoyuan Yu, Shifeng Xiang, Yiping Wu, Xia Meng

Source: Frontiers in Neurology, Vol 15 (2025)

Subject Terms: acute ischemic stroke, type 2 diabetes mellitus, HALP scores, outcome, stroke, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2024.1461188/full; https://doaj.org/toc/1664-2295

Access URL: https://doaj.org/article/653cc898d1064931bdfa3e4de5775e0b

Tumor burden with AFP improves survival prediction for TACE-treated patients with HCC: An international observational study☆

Authors: Dongdong Xia, Wei Bai, Qiuhe Wang, Jin Wook Chung, Xavier Adhoute, Roman Kloeckner, Hui Zhang, Yong Zeng, Pimsiri Sripongpun, Chunhui Nie, Seung Up Kim, Ming Huang, Wenhao Hu, Xiangchun Ding, Guowen Yin, Hailiang Li, Hui Zhao, Jean-Pierre Bronowicki, Jing Li, Jiaping Li, Xiaoli Zhu, Jianbing Wu, Chunqing Zhang, Weidong Gong, Zixiang Li, Zhengyu Lin, Tao Xu, Tao Yin, Rodolphe Anty, Jinlong Song, Haibin Shi, Guoliang Shao, Weixin Ren, Yongjin Zhang, Shufa Yang, Yanbo Zheng, Jian Xu, Wenhui Wang, Xu Zhu, Ying Fu, Chang Liu, Apichat Kaewdech, Rong Ding, Jie Zheng, Shuaiwei Liu, Hui Yu, Lin Zheng, Nan You, Wenzhe Fan, Shuai Zhang, Long Feng, Guangchuan Wang, Peng Zhang, Xueda Li, Jian Chen, Feng Zhang, Wenbo Shao, Weizhong Zhou, Hui Zeng, Gengfei Cao, Wukui Huang, Wenjin Jiang, Wen Zhang, Lei Li, Aiwei Feng, Enxin Wang, Zhexuan Wang, Dandan Han, Yong Lv, Jun Sun, Bincheng Ren, Linying Xia, Xiaomei Li, Jie Yuan, Zhengyu Wang, Bohan Luo, Kai Li, Wengang Guo, Zhanxin Yin, Yan Zhao, Jielai Xia, Daiming Fan, Kaichun Wu, Dominik Bettinger, Arndt Vogel, Guohong Han

Source: JHEP Reports, Vol 7, Iss 1, Pp 101216- (2025)

Subject Terms: Hepatocellular carcinoma, Transarterial chemoembolization, Tumor burden, Alpha-fetoprotein, Risk stratification, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555924002209; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/76421d8f0c9842bb968706dadd45eae0

Integrated multi-omics demonstrates enhanced antitumor efficacy of donafenib combined with FADS2 inhibition in hepatocellular carcinoma

Authors: Hui Li, Yafeng Dai, Di Wu, Song Gao, Jianhai Guo, Pengjun Zhang, Hui Chen, Fuxin Kou, Shaoxing Liu, Aiwei Feng, Baojiang Liu, Dongdong Hou, Xu Zhu

Source: Translational Oncology, Vol 51, Iss , Pp 102142- (2025)

Subject Terms: Hepatocellular carcinoma, Donafenib, Fatty acid desaturase 2, Combination therapy, Multi-omics analysis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1936523324002699; https://doaj.org/toc/1936-5233

Access URL: https://doaj.org/article/1b4354ff9d9d4a5ca07ebc096927f357

BaAM-YOLO: a balanced feature fusion and attention mechanism based vehicle detection network in aerial images

Authors: Xunxun Zhang, Xu Zhu

Source: Journal of Highway and Transportation Research and Development, Vol 18, Iss 3, Pp 48-60 (2024)

Subject Terms: traffic engineering, vehicle detection, balanced feature fusion, attention mechanism, focal loss, Transportation engineering, TA1001-1280

File Description: electronic resource

Relation: https://www.sciopen.com/article/10.26599/HTRD.2024.9480022; https://doaj.org/toc/2095-6215

Access URL: https://doaj.org/article/47c3497cc554495cbce05e4289d8c00a

Nomogram predicting early urinary incontinence after radical prostatectomy

Authors: Cheng Shen, Xu Zhu, Zhan Chen, Wei Zhang, Xinfeng Chen, Bing Zheng, Donghua Gu

Source: BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)

Subject Terms: Prostate cancer, Radical prostatectomy (RP), Urinary incontinence, Urethral pressure profile, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/1553dba50d39453c983955e43b39ac8f

Epigenetic modification of CD4+ T cells into Tregs by 5-azacytidine as cellular therapeutic for atherosclerosis treatment

Authors: Ling Zhu, Zhongwei Liu, Qianwei Cui, Gongchang Guan, Rutai Hui, Xiqiang Wang, Junkui Wang, Yong Zhang, Xu Zhu

Source: Cell Death and Disease, Vol 15, Iss 9, Pp 1-11 (2024)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/53cc96a553d94602a1745cac56cb01cb

3D Printing of Periodic Porous Metamaterials for Tunable Electromagnetic Shielding Across Broad Frequencies

Authors: Qinniu Lv, Zilin Peng, Haoran Pei, Xinxing Zhang, Yinghong Chen, Huarong Zhang, Xu Zhu, Shulong Wu

Source: Nano-Micro Letters, Vol 16, Iss 1, Pp 1-20 (2024)

Subject Terms: Polymeric component, 3D printing, Tunable electromagnetic shielding, Periodic porous metamaterials, Honeycomb pore structure, Technology

File Description: electronic resource

Relation: https://doaj.org/toc/2311-6706; https://doaj.org/toc/2150-5551

Access URL: https://doaj.org/article/213b1dab232e49e09cf42d0609e7a534

Computation of the exact time delay margin for vehicle platoon under generic communication topologies

Authors: Xu Zhu, Maode Yan, Panpan Yang, Yongtao Liu

Source: Journal of Traffic and Transportation Engineering (English ed. Online), Vol 11, Iss 4, Pp 761-775 (2024)

Subject Terms: Vehicle platoon, Exact time delay margin, Generic communication topologies, System decomposition, Characteristic roots' distribution, Transportation engineering, TA1001-1280

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2095756424000734; https://doaj.org/toc/2095-7564

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Multi-omics profiling of retinal pigment epithelium reveals enhancer-driven activation of RANK-NFATc1 signaling in traumatic proliferative vitreoretinopathy

Authors: Mengyu Liao, Xu Zhu, Yumei Lu, Xiaoping Yi, Youhui Hu, Yumeng Zhao, Zhisheng Ye, Xu Guo, Minghui Liang, Xin Jin, Hong Zhang, Xiaohong Wang, Ziming Zhao, Yupeng Chen, Hua Yan

Source: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/a2b0f22db73840dbbb393cee3c110bce

A novel dual-target Septin9 methylation assay for improved detection of early-stage colorectal cancer and high-grade intraepithelial neoplasia

Authors: Youming Wu, Yongqing Tong, Haitao Zhang, Yun Li, Xu Zhu, Ming Li, Lili Qiu, Wenlan Liu, Siqing Mei, Yu Mao, Yanhua Cao, Caiyan Su, Wentao Yu, Junli Wang, Taizhong Wang, Zhongyuan Zhu, De-Hua Yu

Source: BMC Cancer, Vol 24, Iss 1, Pp 1-9 (2024)

Subject Terms: Colorectal cancer (CRC), Methylation, PCR, Septin9, CpG-rich subregions, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/393f1c70317b45dcae5d91530012e13c

Dual-mode ratiometric electrochemical and turn-on fluorescent probe for reliably detecting H2O2 in Parkinson's disease serum

Authors: Hui Dong, Linlin Zheng, Zuying Wang, Ke Xu, Wentian Chen, Zi Liu, Zhu Chang, Yanli Zhou, Xu Zhu, Yintang Zhang, Maotian Xu

Source: Sensors and Actuators Reports, Vol 9, Iss , Pp 100305- (2025)

Subject Terms: Dual-mode, Ratiometric electrochemical, Fluorescent, Parkinson's disease, Hydrogen peroxide, Instruments and machines, QA71-90

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666053925000244; https://doaj.org/toc/2666-0539

Access URL: https://doaj.org/article/19b2f4444c1f4de59cfe49880b5fb519

Prognosis Prediction of Cardiovascular Event With Glucose‐Albumin Ratio on Patients With Cancer and Prescribed With Anthracycline

Authors: Iokfai Cheang, Ying Li, Xu Zhu, Ziqi Chen, Qing‐Wen Ren, Mei‐Zhen Wu, Xin Xu, Hung‐Fat Tse, Kai‐Hang Yiu, Xinli Li

Source: Cancer Medicine, Vol 13, Iss 23, Pp n/a-n/a (2024)

Subject Terms: anthracycline, biomarker, cancer, cardiotoxicity, chemotherapy, GAR, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/88862ed0beb646d689a2c9db22482cc3

Therapeutic potential of EVs loaded with CB2 receptor agonist in spinal cord injury via the Nrf2/HO-1 pathway

Authors: Imran Ibrahim Shaikh, Ramesh Bhandari, Shekhar Singh, Xu Zhu, Khawar Ali Shahzad, Chuxiao Shao, Liming Cheng, Jian Xiao

Source: Redox Report, Vol 29, Iss 1 (2024)

Subject Terms: Spinal cord injury, hUC-MSC-exosome, AM1241, inflammation, oxidative stress, apoptosis, Pathology, RB1-214, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1351-0002; https://doaj.org/toc/1743-2928

Access URL: https://doaj.org/article/283a45b888294baab149e2c2c6e7bbd7

T-cell engagers: model interrogation as a tool to quantify the interplay of relative affinity and target expression on trimer formation

Authors: Massimo Lai, Cesar Pichardo-Almarza, Meghna Verma, Md Shahinuzzaman, Xu Zhu, Holly Kimko

Source: Frontiers in Pharmacology, Vol 15 (2024)

Subject Terms: T-cell engagers, TCEs, TCR, TAA, dose-response, target engagement, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1470595/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/f29c23aa266f4820aa6aa24bd23b7e43