TAp63γ is the primary isoform of TP63 for tumor suppression but not development

Authors: Xinbin Chen, Wenqiang Sun, Xiangmudong Kong, Xin Ming, Yanhong Zhang, Wensheng Yan, Shakur Mohibi, Mingyi Chen, Keith Mitchell, Jin Zhang

Source: Cell Death Discovery, Vol 11, Iss 1, Pp 1-9 (2025)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2058-7716

Access URL: https://doaj.org/article/ca23bfde42934cf8abffa44f07b2e97d

Prognostic significance of fibrinogen levels in sepsis-associated acute kidney injury: unveiling a nonlinear relationship and clinical implications

Authors: Manqin Chen, Xinbin Chen, Huaxiang Ling, Chengwen Bai, Lihua Chen, Lin Zhong, Ping Gong, Fei Shi

Source: Frontiers in Nephrology, Vol 4 (2024)

Subject Terms: fibrinogen, sepsis, acute kidney injury, sepsis-associated acute kidney injury, mortality, medical information mart for intensive care-IV, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneph.2024.1398386/full; https://doaj.org/toc/2813-0626

Access URL: https://doaj.org/article/007c4f49221545dcba9f174a8dd5308f

Development of Novel Peptides That Target the Ninjurin 1 and 2 Pathways to Inhibit Cell Growth and Survival via p53

Authors: Jin Zhang, Xiangmudong Kong, Xinbin Chen

Source: Cells, Vol 14, Iss 6, p 401 (2025)

Subject Terms: Ninjurin 1, Ninjuring 2, peptide, p53, cancer treatment, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/14/6/401; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/5a68c2b5502648f6b1199f386291a107

Ferredoxin 1 is essential for embryonic development and lipid homeostasis

Authors: Shakur Mohibi, Yanhong Zhang, Vivian Perng, Mingyi Chen, Jin Zhang, Xinbin Chen

Source: eLife, Vol 13 (2024)

Subject Terms: ferredoxin 1, ferredoxin reductase, lipidomics, lipid homeostasis, steatohepatitis, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/91656; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/43a44f2d4ef144da9f7b413f62c39002

TP73 Isoform-specific disruption reveals a critical role of TAp73beta in growth suppression and inflammatory response

Authors: Jin Zhang, Wenqiang Sun, Wensheng Yan, Xiangmudong Kong, Tong Shen, Kyra Laubach, Mingyi Chen, Xinbin Chen

Source: Cell Death and Disease, Vol 14, Iss 1, Pp 1-12 (2023)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/54bc7e824f7646598604f6d03f28f446

Isoform-specific disruption of the TP73 gene reveals a critical role for TAp73γ in tumorigenesis via leptin

Authors: Xiangmudong Kong, Wensheng Yan, Wenqiang Sun, Yanhong Zhang, Hee Jung Yang, Mingyi Chen, Hongwu Chen, Ralph W de Vere White, Jin Zhang, Xinbin Chen

Source: eLife, Vol 12 (2023)

Subject Terms: TAp73, p53, Leptin, oncogenesis, obesity, TAp73γ, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/82115; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/3d0f73f2102d4f66a7d02282d5fbfdc7

The RNA-binding protein RBM24 regulates lipid metabolism and SLC7A11 mRNA stability to modulate ferroptosis and inflammatory response

Authors: Jin Zhang, Xiangmudong Kong, Wenqiang Sun, Leyi Wang, Tong Shen, Mingyi Chen, Xinbin Chen

Source: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Subject Terms: Rbm24, Rbm38, SLC7A11, ferroptosis, inflammatory response, mRNA stability, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2022.1008576/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/2dd41c75231f4858b70b2942b6742ec4

Optimization of eIF4E-Binding Peptide Pep8 to Disrupt the RBM38-eIF4E Complex for Induction of p53 and Tumor Suppression

Authors: Christopher A. Lucchesi, Jin Zhang, Demitria M. Vasilatis, Elizabeth Yip, Xinbin Chen

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: eIF4E, RBM38, p53, eIF4E-binding peptide, peptide, radiotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.893062/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/474d26c584464e12832d09e5fcb5c78a

RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype

Authors: Demin Cai, Junjian Wang, Bei Gao, Jin Li, Feng Wu, June X. Zou, Jianzhen Xu, Yuqian Jiang, Hongye Zou, Zenghong Huang, Alexander D. Borowsky, Richard J. Bold, Primo N. Lara, Jian Jian Li, Xinbin Chen, Kit S. Lam, Ka-Fai To, Hsing-Jien Kung, Oliver Fiehn, Ruqian Zhao, Ronald M. Evans, Hong-Wu Chen

Source: Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/985e83249405455e850f73d41a842e97

The p53 Family: A Role in Lipid and Iron Metabolism

Authors: Kyra Laubach, Jin Zhang, Xinbin Chen

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: p53, p63, p73, metabolism, lipid, iron, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.715974/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/0b0fca381a3f44c9bd5aa92b30ccb6fb

p73α1, an Isoform of the p73 Tumor Suppressor, Modulates Lipid Metabolism and Cancer Cell Growth via Stearoyl-CoA Desaturase-1

Authors: Zachary Rabow, Kyra Laubach, Xiangmudong Kong, Tong Shen, Shakur Mohibi, Jin Zhang, Oliver Fiehn, Xinbin Chen

Source: Cells, Vol 11, Iss 16, p 2516 (2022)

Subject Terms: p73 isoforms, the p53 family, Stearoyl-CoA Desaturase, lipid metabolism, Kennedy pathway, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/16/2516; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/83b2b5ee08cd4db5b966da33b2891c24

Correction: PUMA Cooperates with p21 to Regulate Mammary Epithelial Morphogenesis and Epithelial-To-Mesenchymal Transition.

Authors: Yanhong Zhang, Wensheng Yan, Yong Sam Jung, Xinbin Chen

Source: PLoS ONE, Vol 15, Iss 8, p e0237624 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/83795ab3a62e45f991ab54a5930ef3ea

DEC1 coordinates with HDAC8 to differentially regulate TAp73 and ΔNp73 expression.

Authors: Yingjuan Qian, Jin Zhang, Yong-Sam Jung, Xinbin Chen

Source: PLoS ONE, Vol 9, Iss 1, p e84015 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3880278?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/507c57d90c1a4a7fbf66404d79f97ba5

Arsenic trioxide reactivates proteasome-dependent degradation of mutant p53 protein in cancer cells in part via enhanced expression of Pirh2 E3 ligase.

Authors: Wensheng Yan, Yong-Sam Jung, Yanhong Zhang, Xinbin Chen

Source: PLoS ONE, Vol 9, Iss 8, p e103497 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4130519?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/829567fa38894f0282368940e22f7cff

Poly (C)-binding protein 1 regulates p63 expression through mRNA stability.

Authors: Seong-Jun Cho, Yong-Sam Jung, Xinbin Chen

Source: PLoS ONE, Vol 8, Iss 8, p e71724 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3737132?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/39caa0490cd146febc010f751a8b57c6

PUMA Cooperates with p21 to Regulate Mammary Epithelial Morphogenesis and Epithelial-To-Mesenchymal Transition.

Authors: Yanhong Zhang, Wensheng Yan, Yong Sam Jung, Xinbin Chen

Source: PLoS ONE, Vol 8, Iss 6, p e66464 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3689819?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/3c9db4046dfa4febab8522c70c09d3a0

Mutant p53 cooperates with knockdown of endogenous wild-type p53 to disrupt tubulogenesis in Madin-Darby canine kidney cells.

Authors: Yanhong Zhang, Wensheng Yan, Xinbin Chen

Source: PLoS ONE, Vol 8, Iss 12, p e85624 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3874028?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/f26cc2ee80a743b6a100fda6986ee6d9

MicroRNA let-7c is downregulated in prostate cancer and suppresses prostate cancer growth.

Authors: Nagalakshmi Nadiminty, Ramakumar Tummala, Wei Lou, Yezi Zhu, Xu-Bao Shi, June X Zou, Hongwu Chen, Jin Zhang, Xinbin Chen, Jun Luo, Ralph W deVere White, Hsing-Jien Kung, Christopher P Evans, Allen C Gao

Source: PLoS ONE, Vol 7, Iss 3, p e32832 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3316551?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/9a02ec23e9174007b2847f00a64e2340

Fluoroquinolone-mediated inhibition of cell growth, S-G2/M cell cycle arrest, and apoptosis in canine osteosarcoma cell lines.

Authors: Kyoung won Seo, Roseline Holt, Yong-Sam Jung, Carlos O Rodriguez, Xinbin Chen, Robert B Rebhun

Source: PLoS ONE, Vol 7, Iss 8, p e42960 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3424257?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/6a1d1a0f6b774309ab92f7d221144ae7

HuR is necessary for mammary epithelial cell proliferation and polarity at least in part via ΔNp63.

Authors: Wensheng Yan, Yanhong Zhang, Jin Zhang, Seong-Jun Cho, Xinbin Chen

Source: PLoS ONE, Vol 7, Iss 9, p e45336 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3445479?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/c811b44fd3244a3abf0bcb7b98661eb7