AML typical mutations (CEBPA, FLT3, NPM1) identify a high-risk chronic myelomonocytic leukemia independent of CPSS molecular

Authors: Castaño-Díez, Sandra ^{1, 2}, López-Guerra, Mònica ^{1, 3}, Zugasti, Inés ^{2, 4}, Calvo, Xavier ^{2, 5}, Schulz, Felicitas Isabel ⁶, Avendaño, Alejandro ^{2, 7}, Mora, Elvira ^{2, 8}, Falantes, José ^{2, 9}, Azaceta, Gemma ^{2, 10}, Ibáñez, Mariam ^{2, 11}, Chen, Tzu ^{2, 12}, Notario, Cristina ^{2, 13}, Amer, Neus ^{2, 14}, Palomo, Laura ^{2, 15}, Pomares, Helena ^{2, 16}, Vila, Jordi ^{2, 17}, Bernal del Castillo, Teresa ^{2, 18}, Jiménez-Vicente, Carlos ⁴, Esteban, Daniel ¹⁹, Guijarro, Francesca ¹, Álamo, José ^{1, 2}, Cortés-Bullich, Albert ⁴, Torrecillas-Mayayo, Víctor ²⁰, Triguero, Ana ⁴, Mont-de Torres, Lucía ²⁰, Carcelero, Ester ²¹, Cardús, Aina ¹, Germing, Ulrich ⁶, Betz, Beate ²², Rozman, Maria ^{1, 2}, Arenillas, Leonor ^{2, 5}, Zamora, Lurdes ^{2, 19}, Díez-Campelo, María ^{2, 7}, Xicoy, Blanca ^{2, 19}, Esteve, Jordi ⁴, Díaz-Beyá, Marina ^{2, 4, ∗}

Source: In Blood Advances 14 January 2025 9(1):39-53

Influence of TP53 gene mutations and their allelic status in myelodysplastic syndromes with isolated 5q deletion

Authors: Montoro, Maria Julia, Palomo, Laura, Haferlach, Claudia, Acha, Pamela, Chan, Onyee, Navarro, Víctor, Kubota, Yasuo, Schulz, Felicitas Isabel, Meggendorfer, Manja, Briski, Robert, Al Ali, Najla, Xicoy, Blanca, López-Cadenas, Félix, Bosch, Francesc, González, Teresa, Eder, Lea Naomi, Jerez, Andrés, Wang, Yu-Hung, Campagna, Alessia, Santini, Valeria, Bernal del Castillo, Teresa, Such, Esperanza, Tien, Hwei-Fang, Diaz Varela, Nicolás, Platzbecker, Uwe, Haase, Detlef, Díez-Campelo, María, Della Porta, Matteo, Garcia-Manero, Guillermo, Wiseman, Daniel H., Germing, Ulrich, Maciejewski, Jaroslaw P., Komrokji, Rami S., Sole, Francesc, Haferlach, Torsten, Valcárcel, David

Source: In Blood 17 October 2024 144(16):1722-1731

Efficacy and safety of fedratinib in patients with myelofibrosis previously treated with ruxolitinib (FREEDOM2): results from a multicentre, open-label, randomised, controlled, phase 3 trial

Authors: Harrison, Claire N ^*, Mesa, Ruben, Talpaz, Moshe, Al-Ali, Haifa Kathrin, Xicoy, Blanca, Passamonti, Francesco, Palandri, Francesca, Benevolo, Giulia, Vannucchi, Alessandro Maria, Mediavilla, Clemence, Iurlo, Alessandra, Kim, InHo, Rose, Shelonitda, Brown, Patrick, Hernandez, Christopher, Wang, Jia, Kiladjian, Jean-Jacques

Source: In The Lancet Haematology October 2024 11(10):e729-e740

Low dose lenalidomide versus placebo in non-transfusion dependent patients with low risk, del(5q) myelodysplastic syndromes (SintraREV): a randomised, double-blind, phase 3 trial

Authors: Díez-Campelo, María ^*, López-Cadenas, Félix, Xicoy, Blanca, Lumbreras, Eva, González, Teresa, del Rey González, Mónica, Sánchez-García, Joaquín, Coll Jordà, Rosa, Slama, Bohrane, Hernández-Rivas, Jose-Ángel, Thepot, Sylvain, Bernal, Teresa, Guerci-Bresler, Agnès, Bargay, Joan, Amigo, María Luz, Preudhomme, Claude, Fenwarth, Laurene, Platzbecker, Uwe, Götze, Katharina S, Arar, Ali, Toribio, Sofía, Del Cañizo, Consuelo, Hernández-Rivas, Jesús María, Fenaux, Pierre

Source: In The Lancet Haematology September 2024 11(9):e659-e670

Phase 1 study of JNJ-64619178, a protein arginine methyltransferase 5 inhibitor, in patients with lower-risk myelodysplastic syndromes

Authors: Haque, Tamanna, Cadenas, Felix López, Xicoy, Blanca, Alfonso-Pierola, Ana, Platzbecker, Uwe, Avivi, Irit, Brunner, Andrew M., Chromik, Jöerg, Morillo, Daniel, Patel, Manish R., Falantes, Jose, Leitch, Heather A., Germing, Ulrich, Preis, Meir, Lenox, Laurie, Lauring, Josh, Brown, Regina J., Kalota, Anna, Mehta, Jaydeep, Pastore, Friederike, Gu, Junchen, Mistry, Pankaj, Valcárcel, David

Source: In Leukemia Research November 2023 134

Momelotinib long-term safety and survival in myelofibrosis: integrated analysis of phase 3 randomized controlled trials

Authors: Verstovsek, Srdan, Mesa, Ruben, Gupta, Vikas, Lavie, David, Dubruille, Viviane, Cambier, Nathalie, Platzbecker, Uwe, Hus, Marek, Xicoy, Blanca, Oh, Stephen T., Kiladjian, Jean-Jacques, Vannucchi, Alessandro M., Gerds, Aaron, Egyed, Miklos, Mayer, Jiří, Sacha, Tomasz, Kawashima, Jun, Morris, Marc, Huang, Mei, Harrison, Claire

Source: In Blood Advances 25 July 2023 7(14):3582-3591

Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis (MOMENTUM): results from an international, double-blind, randomised, controlled, phase 3 study

Authors: Abulafia, Adi Shacham, Al-Ali, Haifa Kathrin, Andreasson, Bjorn, Angona, Anna, Ayala, Rosa, Bang, Soo-Mee, Bank, Bruce, Barraco, Fiorenza, Beggiato, Eloise, Benghiat, Fleur Samantha, Bonifacio, MassimiliaNo, Bories, Claire, Borsaru, Gabriela, Brabrand, Mette, Braester, Andrei, Broliden, Andes, Buxhofer-Ausch, Veronika, Cambier, Nathalie, Caramella, Marianna, Carpentier, Benjamin, Cascavilla, Nicola, Castellano, Maria Giraldo, Chang, Hung, Chen, Chih-Cheng, Cheong, June-Won, Choi, Yunsuk, Choi, Philip, Corsetti, Maria Teresa, Cuadrado, Isabel Montero, Cunningham, Julia, Damaj, Gandhi Laurent, De Stefano, Valerio, Delage, Robert, Delgado, Regina Garcĺa, Diaz, Jose Miguel Torregrosa, Dombi, Péter, Dubruille, Viviane, Egyed, Miklós, El Fassi, Daniel, Elinder-Camburn, Anna, Elli, Elena Maria, Ellis, Martin, Fava, Carmen, Fazal, Salman, Fleischman, Angela, Foltz, Lynda, Fox, Laura, Gabrail, Nashat, Garcĺa-Gutiérrez, Jose Valentĺn, Gerds, Aaron, Girault, Stephane, Gisslinger, Heinz, Gluvacov, Alexandru, Goh, Yeow Tee, Göthert, Joachim, Granacher, Nikki, Grosicki, Sebastian, Gupta, Vikas, Hadjiev (Hadzhiev), Evgeni (Evgueniy), Hafraoui, Kaoutar, Hamed, Aryan, Harrison, Claire, Hasselbalch, Hans, Hauser, Hanns, Heaney, Mark, Hebart, Holger, Hernandez Rivas, Jesus Maria, Higuero Saavedra, Victor, Hillis, Christopher, Hou, Hsin-An, How, Jonathan, Huang, Daniel, Hus, Marek, Illés, Arpad, Isidori, Alessandro, Iurlo, Alessandra, Ivanov, Vadim, Johansson, Peter, Jung, Chul Won, Kiladjian, Jean-Jacques, Kirgner, Ilya, Koren-Michowitz, Maya, Koschmieder, Steffen, Kosztolanyi, Szabolcs Ors, Kreiniz, Natalia, Kuykendall, Andrew, Lambert, Jonathan, Laribi, Kamel, Lascaux, Axelle, Lavie, Noa, Lavie, David, Lazaroiu, Mihaela, Leahy, Michael, Lech-Maranda, Ewa, Lee, Sung-Eun, Lee, Won Sik, Legrand, Ollivier, Lemoli, Roberto, Liang, James, Lim, Sung-Nam, Loschi, Michael, Lucchesi, Alessandro, Macarie, Ioan, Marolleau, Jean-Pierre, Martelli, Maurizio, Mayer, Jiri, McCloskey, James, McDermott, Christopher, McLornan, Donal, McMahon, Brandon, Mehta, Priyanka, Mesa, Ruben, Mikala, Gábor, Milojkovic, Dragana, Mineur, Philippe, Mishchenko, Elena, Moon, Joon Ho, Nagy, Zsolt, Narayanan, Srinivasan, O'Connell, Casey, Ocroteala, Luminita, Oh, Stephen, Ojeda-Uribe, Mario, Ong, Kiat Hoe, Otegbeye, Folashade, Palmer, Jeanne, Pane, Fabrizio, Passamonti, Francesco, Patriarca, Andrea, Perkins, Andrew, Pietrantuono, Giuseppe, Plander, Mark, Platzbecker, Uwe, Prasad, Ritam, Prejzner, Witold, Rachow, Tobias, Radinoff, Atanas, Rejtő, László, Rinaldi, Ciro, Robak, Tadeusz, Rodriguez, Maria Angeles Fernandez, Ronson, Aaron, Ross, David, Sacha, Tomasz, Sadjadian, Parvis, Salar, Antonio, Santillana, Guillermo Sanz, Scheid, Christof, Schmidt, Aline, Severinsen, Marianne Tang, Stoeva, Vera, Szwedyk, Paweł, Tiribelli, Mario, Trautmann-Grill, Karolin, Trottier, Amy, Tzvetkov, Nikolay, van Droogenbroeck, Janusz, Vannucchi, Alessandro, Verstovsek, Srdan, Vianelli, Nicola, von Bubnoff, Nikolas, Wolf, Dominik, Woszczyk, Dariusz, Woźny, Tomasz, Wróbel, Tomasz, Xicoy, Blanca, Yeh, Su-Peng, Yoon, Sung-Soo, Gerds, Aaron T, Vannucchi, Alessandro M, Kuykendall, Andrew T, Lazaroiu, Mihaela C, Egyed, Miklos, Fox, Maria Laura, Harrison, Claire N, Klencke, Barbara J, Ro, Sunhee, Donahue, Rafe, Kawashima, Jun

Source: In The Lancet 28 January 2023 401(10373):269-280

Natural killer cell receptors and ligand variants modulate response to tyrosine kinase inhibitors in patients with chronic myeloid leukemia

Authors: Closa, Laia, Xicoy, Blanca, Zamora, Lurdes, Estrada, Natalia, Colomer, Dolors, Herrero, Maria J., Vidal, Francisco, Alvarez‐Larrán, Alberto, Caro, Jose L.

Source: HLA. 99(2):93-104

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139316919.0x000001&indx=1&recIds=ETOCvdc_100139316919.0x000001

Predictors of thrombosis and bleeding in 1613 myelofibrosis patients from the Spanish Registry of Myelofibrosis

Authors: Hernández‐Boluda, Juan‐Carlos, Pastor‐Galán, Irene, Arellano‐Rodrigo, Eduardo, Raya, José‐María, Pérez‐Encinas, Manuel, Ayala, Rosa, Ferrer‐Marín, Francisca, Velez, Patricia, Mora, Elvira, Fox, María‐Laura, Hernández‐Rivas, Jesús‐María, Xicoy, Blanca, Mata‐Vázquez, María‐Isabel, García‐Fortes, María, Pérez‐López, Raúl, Angona, Anna, Cuevas, Beatriz, Senín, Alicia, Ramírez, María‐José, Ramírez‐Payer, Angel, Gómez‐Casares, María‐Teresa, Martínez‐Valverde, Clara, Magro, Elena, Steegmann, Juan‐Luis, Durán, María‐Antonia, García‐Hernández, Carmen, Gasior, Mercedes, Villambrosia, Sonia González, Alvarez‐Larrán, Alberto, Pereira, Arturo

Source: British journal of haematology. 199(4):529-538

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165058638.0x000001&indx=1&recIds=ETOCvdc_100165058638.0x000001

Real‐world analysis of main clinical outcomes in patients with polycythemia vera treated with ruxolitinib or best available therapy after developing resistance/intolerance to hydroxyurea

Authors: Alvarez‐Larrán, Alberto, Garrote, Marta, Ferrer‐Marín, Francisca, Pérez‐Encinas, Manuel, Mata‐Vazquez, M. Isabel, Bellosillo, Beatriz, Arellano‐Rodrigo, Eduardo, Gómez, Montse, García, Regina, García‐Gutiérrez, Valentín, Gasior, Mercedes, Cuevas, Beatriz, Angona, Anna, Gómez‐Casares, María Teresa, Martínez, Clara M., Magro, Elena, Ayala, Rosa, Orbe‐Barreto, Rafael, Pérez‐López, Raúl, Fox, Maria Laura, Raya, José‐María, Guerrero, Lucía, García‐Hernández, Carmen, Caballero, Gonzalo, Murillo, Ilda, Xicoy, Blanca, Ramírez, M. José, Carreño‐Tarragona, Gonzalo, Hernández‐Boluda, Juan Carlos, Pereira, Arturo

Source: Cancer. 128(13):2441-2448

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100153653875.0x000001&indx=1&recIds=ETOCvdc_100153653875.0x000001

Pathophysiologic and clinical implications of molecular profiles resultant from deletion 5q

Authors: Adema, Vera, Palomo, Laura, Walter, Wencke, Mallo, Mar, Hutter, Stephan, La Framboise, Thomas, Arenillas, Leonor, Meggendorfer, Manja, Radivoyevitch, Tomas, Xicoy, Blanca, Pellagatti, Andrea, Haferlach, Claudia, Boultwood, Jacqueline, Kern, Wolfgang, Visconte, Valeria, Sekeres, Mikkael, Barnard, John, Haferlach, Torsten, Solé, Francesc, Maciejewski, Jaroslaw P.

Source: In eBioMedicine June 2022 80

Proposed global prognostic score for systemic mastocytosis: a retrospective prognostic modelling study

Authors: Muñoz-González, Javier I, Álvarez-Twose, Iván, Jara-Acevedo, María, Zanotti, Roberta, Perkins, Cecelia, Jawhar, Mohamad, Sperr, Wolfgang R, Shoumariyeh, Khalid, Schwaab, Juliana, Greiner, Georg, Henriques, Ana, Caldas, Carolina, Fernández-Giménez, Carlos, Sánchez-Muñoz, Laura, Mayado, Andrea, Pérez-Pons, Alba, Schmitt-Graeff, Annette, Duyster, Justus, Tanasi, Ilaria, Olivieri, Francesco, Mora-Casterá, Elvira, Luna, Irene, Senent, Leonor, Bañas, Maria-Helena, Nuñez-García, Amanda, Jurado-Chacón, Manuel, Martín-Sánchez, Guillermo, Colado, Enrique, Xicoy, Blanca, Gener-Ricós, Georgina, Gotlib, Jason, Bonadonna, Patrizia, Reiter, Andreas, Valent, Peter, García-Montero, Andrés C, Orfao, Alberto ^*

Source: In The Lancet Haematology March 2021 8(3):e194-e204

Myelodysplastic syndromes with 20q deletion: incidence, prognostic value and impact on response to azacitidine of ASXL1 chromosomal deletion and genetic mutations

Authors: Martín, Iván, Villamón, Eva, Abellán, Rosario, Calasanz, Maria José, Irigoyen, Aroa, Sanz, Guillermo, Such, Esperanza, Mora, Elvira, Gutiérrez, Míriam, Collado, Rosa, García‐Serra, Rocío, Vara, Míriam, Blanco, Mª Laura, Oiartzabal, Itziar, Álvarez, Sara, Bernal, Teresa, Granada, Isabel, Xicoy, Blanca, Jerez, Andrés, Calabuig, Marisa, Diez, Rosana, Gil, Ángela, Díez-Campelo, María, Solano, Carlos, Tormo, Mar

Source: British journal of haematology. 194(4):708-717

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127364034.0x000001&indx=1&recIds=ETOCvdc_100127364034.0x000001

Chronic myelomonocytic leukemia and blastic plasmacytoid dendritic cell neoplasm. A case report and systematic review

Authors: Espasa, Andrea, Sorigue, Marc, Tapia, Gustavo, Cabezon, Marta, Vergara, Sara, Raya, Minerva, Navarro, Jose‐Tomas, Junca, Jordi, Zamora, Lurdes, Xicoy, Blanca

Source: Cytometry.Part B.Clinical cytometry. 100(3):292-295

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121105021.0x000001&indx=1&recIds=ETOCvdc_100121105021.0x000001

Quantification of Histone H1 Subtypes Using Targeted Proteomics.

Authors: López-Gómez, Jordi, Villarreal, Laura, Andrés, Marta, Ponte, Inma, Xicoy, Blanca, Zamora, Lurdes, Vilaseca, Marta, Roque, Alicia

Source: Biomolecules (2218-273X); Oct2024, Vol. 14 Issue 10, p1221, 18p

Subject Terms: CHRONIC myeloid leukemia, PROTEIN-tyrosine kinase inhibitors, SOMATIC cells, IMATINIB, WESTERN immunoblotting

Beyond myeloid neoplasms germline guidelines: Validation of the thresholds criteria in the search of germline predisposition variants.

Authors: Mestre, Julia, Chaparro, Lorea, Manzanares, Ana, Xicoy, Blanca, Zamora, Lurdes, Sole, Francesc, Calvete, Oriol

Source: EJHaem; Oct2024, Vol. 5 Issue 5, p1021-1027, 7p

Predicting Survival after Allogeneic Hematopoietic Cell Transplantation in Myelofibrosis: Performance of the Myelofibrosis Transplant Scoring System (MTSS) and Development of a New Prognostic Model

Authors: Hernández-Boluda, Juan-Carlos, Pereira, Arturo, Alvarez-Larran, Alberto, Martín, Ana-Africa, Benzaquen, Ana, Aguirre, Lourdes, Mora, Elvira, González, Pedro, Mora, Jorge, Dorado, Nieves, Sampol, Antonia, García-Gutiérrez, Valentín, López-Godino, Oriana, Fox, María-Laura, Reguera, Juan Luis, Pérez-Encinas, Manuel, Pascual, María-Jesús, Xicoy, Blanca, Parody, Rocío, González-Pinedo, Leslie, Español, Ignacio, Avendaño, Alejandro, Correa, Juan-Gonzalo, Vallejo, Carlos, Jurado, Manuel, García-Cadenas, Irene, Osorio, Santiago, Durán, María-Antonia, Sánchez-Guijo, Fermín, Cervantes, Francisco, Piñana, José-Luis

Source: In Biology of Blood and Marrow Transplantation December 2020 26(12):2237-2244

Impact of previous admission to an intensive care unit on stem cell transplantation outcome

Alternate Title: Impacto de un ingreso previo en una unidad de medicina intensiva sobre los resultados del trasplante hematopoyético (Spanish; Castilian)

Authors: Sarrate, Edurne, Jiménez, Maria-José, Morgades, Mireia, Marcos, Pilar, Ricart, Pilar, Vives, Susana, Xicoy, Blanca, Torrent, Anna, Misis, María-Teresa, Bordeje, Maria-Luisa, Batlle, Montserrat, Moreno, Miriam, Sancho, Juan-Manuel, Ribera, Josep-Maria, Ferra, Christelle

Source: In Medicina Clínica (English Edition) 13 November 2020 155(9):382-387

Molecular landscape and clonal architecture of adult myelodysplastic/myeloproliferative neoplasms

Authors: Palomo, Laura ¹, Meggendorfer, Manja ², Hutter, Stephan ², Twardziok, Sven ², Ademà, Vera ³, Fuhrmann, Irene ², Fuster-Tormo, Francisco ¹, Xicoy, Blanca ⁴, Zamora, Lurdes ⁴, Acha, Pamela ¹, Kerr, Cassandra M. ³, Kern, Wolfgang ², Maciejewski, Jaroslaw P. ³, Solé, Francesc ¹, Haferlach, Claudia ^{1, 2}, Haferlach, Torsten ²

Source: In Blood 15 October 2020 136(16):1851-1862

Early Prediction of Subsequent Molecular Response to Nilotinib in Patients with Chronic Myeloid Leukemia: Comparison of the Quantification of BCR-ABL1 Ratios Using ABL1 or GUSB Control Genes

Authors: Stuckey, Ruth, Casado, Luis-Felipe, Colomer, Dolors, Gómez-Casares, María Teresa, Casas, Laura, García-Gutierrez, Valentín, Sastre, José Luis, Ramírez-Payer, Ángel, Vall-Llovera, Ferrán, Goñi, María Ángeles, Xicoy, Blanca, Godoy, Ana Cristina, Núñez, Javier, Mora, Itxaso, Vallansot, Rolando, López-Lorenzo, José Luis, Palomera, Luis, Conesa, Venancio, Noya, María Soledad, Sánchez-Guijo, Fermín, Peña, Ascensión, Bautista, Guiomar, Steegmann, Juan Luis

Source: In The Journal of Molecular Diagnostics October 2020 22(10):1217-1224