Synergistic effects of Smac mimetic APG-1387 with anti-PD-1 antibody are attributed to increased CD3 + NK1.1 + cell recruitment secondary to induction of cytokines from tumor cells

Authors: Wentao Pan, Qiuyun Luo, Eric Liang, Mude Shi, Jian Sun, Huimin Shen, Zhenhai Lu, Lin Zhang, Xianglei Yan, Luping Yuan, Suna Zhou, Hanjie Yi, Yifan Zhai, Miao-zhen Qiu, Dajun Yang

Source: Cancer Cell International, Vol 24, Iss 1, Pp 1-13 (2024)

Subject Terms: Smac mimetic, APG-1387, Combination therapy, Immunotherapy, CD3 + NK1.1 + cells, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2867

Access URL: https://doaj.org/article/351b402f688449ceb4c6ca9f401e8dfc

Fcγ-Receptor-Independent Controlled Activation of CD40 Canonical Signaling by Novel Therapeutic Antibodies for Cancer Therapy

Authors: Karsten Beckmann, Carmen Reitinger, Xianglei Yan, Anna Carle, Eva Blümle, Nicole Jurkschat, Claudia Paulmann, Sandra Prassl, Linda V. Kazandjian, Karin Loré, Falk Nimmerjahn, Stephan Fischer

Source: Antibodies, Vol 13, Iss 2, p 31 (2024)

Subject Terms: CD40, antibody, dendritic cell, immunoglobulin, immune cell activation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4468/13/2/31; https://doaj.org/toc/2073-4468

Access URL: https://doaj.org/article/365c7b3037aa408db99a37f815277aa8

A third dose of the unmodified COVID-19 mRNA vaccine CVnCoV enhances quality and quantity of immune responses

Authors: Klara Lenart, Fredrika Hellgren, Sebastian Ols, Xianglei Yan, Alberto Cagigi, Rodrigo Arcoverde Cerveira, Inga Winge, Jakub Hanczak, Stefan O. Mueller, Edith Jasny, Kim Schwendt, Susanne Rauch, Benjamin Petsch, Karin Loré

Source: Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 309-323 (2022)

Subject Terms: vaccine, mRNA vaccine, antibody response, affinity maturation, vaccine biodistribution, innate immunity, Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050122001437; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/7fe635994c564778a82c953e5d6c3cf7

Bcl‐2/Bcl‐xl inhibitor APG‐1252‐M1 is a promising therapeutic strategy for gastric carcinoma

Authors: Hanjie Yi, Miao‐Zhen Qiu, Luping Yuan, Qiuyun Luo, Wentao Pan, Suna Zhou, Lin Zhang, Xianglei Yan, Da‐Jun Yang

Source: Cancer Medicine, Vol 9, Iss 12, Pp 4197-4206 (2020)

Subject Terms: APG‐1252‐M1, apoptosis, Bcl‐2/Bcl‐xl inhibitor, gastric cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/6d3d315277894e3ab1c21328cee0f491

Preclinical development of HQP1351, a multikinase inhibitor targeting a broad spectrum of mutant KIT kinases, for the treatment of imatinib-resistant gastrointestinal stromal tumors

Authors: Xuechao Liu, Guangfeng Wang, Xianglei Yan, Haibo Qiu, Ping Min, Miaoyi Wu, Chunyang Tang, Fei Zhang, Qiuqiong Tang, Saijie Zhu, Miaozhen Qiu, Wei Zhuang, Douglas D. Fang, Zhiwei Zhou, Dajun Yang, Yifan Zhai

Source: Cell & Bioscience, Vol 9, Iss 1, Pp 1-12 (2019)

Subject Terms: Gastrointestinal stromal tumor, Drug resistance, Kit tyrosine kinase, Imatinib, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13578-019-0351-6; https://doaj.org/toc/2045-3701

Access URL: https://doaj.org/article/684f49e1df854ee8a1b2931e36258433

A novel small molecule inhibitor of MDM2-p53 (APG-115) enhances radiosensitivity of gastric adenocarcinoma

Authors: Hanjie Yi, Xianglei Yan, Qiuyun Luo, Luping Yuan, Baoxia Li, Wentao Pan, Lin Zhang, Haibo Chen, Jing Wang, Yubin Zhang, Yifan Zhai, Miao-Zhen Qiu, Da-Jun Yang

Source: Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-10 (2018)

Subject Terms: Small molecule inhibitors, MDM2, p53, Gastric cancer, Radiation, Apoptosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13046-018-0765-8; https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/741ca8ab6c9e4e2bb0e4bb81ca774357

Integrated soil moisture fusion for enhanced agricultural drought monitoring in China

Authors: Aifeng Lv, Xianglei Yang, Wenxiang Zhang, Yan Han

Source: Agricultural Water Management, Vol 311, Iss , Pp 109401- (2025)

Subject Terms: Data fusion, Triple collocation, Soil moisture, Spatiotemporal analysis, Drought monitoring, Agriculture (General), S1-972, Agricultural industries, HD9000-9495

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0378377425001155; https://doaj.org/toc/1873-2283

Access URL: https://doaj.org/article/640f482a3a7e4a8a897a86ea640350a5

Point-to-Multipoint Phase-Stabilized Microwave Signal Transmission in Optical Fiber Links Using Passive Phase Compensation

Authors: Yao, Jiang, Xihua, Zou, Xianglei, Yan

Source: Guang xue xue bao. 39(9):0906005-0906005

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN622643503&indx=1&recIds=ETOCRN622643503

APG-1252-12A induces mitochondria-dependent apoptosis through inhibiting the antiapoptotic proteins Bcl-2/Bcl-xl in HL-60 cells.

Authors: JING WANG, DAJUN YANG, QIUYUN LUO, MIAOZHEN QIU, LIN ZHANG, BAOXIA LI, HAIBO CHEN, HANJIE YI, XIANGLEI YAN, SHUXIA LI, JIAN SUN

Source: International Journal of Oncology; Aug2017, Vol. 51 Issue 2, p563-572, 10p

Wideband Doppler frequency shift measurement and direction ambiguity resolution using optical frequency shift and optical heterodyning.

Authors: Bing Lu¹, Wei Pan¹, Xihua Zou^1,2, zouxihua@swjtu.edu.cn, Xianglei Yan¹, Lianshan Yan¹, Bin Luo¹

Source: Optics Letters; 5/15/2015, Vol. 40 Issue 10, p2321-2324, 4p