Increased melanin induces aberrant keratinocyte − melanocyte − basal − fibroblast cell communication and fibrogenesis by inducing iron overload and ferroptosis resistance in keloids

Authors: Xiangguang Shi, Xueyi Xia, Yang Xiao, Ying Zhang, Yiyi Gong, Yahui Chen, Chenyi Shi, Wei Wang, Jianlan Liu, Jia Huang, Mengguo Liu, Zhuoya Xu, Yanyun Ma, Mengkun Shi, Jiucun Wang, Wenyu Wu

Source: Cell Communication and Signaling, Vol 23, Iss 1, Pp 1-21 (2025)

Subject Terms: Keloid, Melanin, Fibrogenesis, Iron overload, Ferroptosis resistance, Medicine, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1478-811X

Access URL: https://doaj.org/article/f2ecd73a2d5b49688c0d1c68570554f1

The novel molecular mechanism of pulmonary fibrosis: insight into lipid metabolism from reanalysis of single-cell RNA-seq databases

Authors: Xiangguang Shi, Yahui Chen, Mengkun Shi, Fei Gao, Lihao Huang, Wei Wang, Dong Wei, Chenyi Shi, Yuexin Yu, Xueyi Xia, Nana Song, Xiaofeng Chen, Jörg H. W. Distler, Chenqi Lu, Jingyu Chen, Jiucun Wang

Source: Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-19 (2024)

Subject Terms: Pulmonary fibrosis, Lipid metabolism, Lipid metabolomic gene, Single-cell RNA-sequencing reanalysis, Nutritional diseases. Deficiency diseases, RC620-627

File Description: electronic resource

Relation: https://doaj.org/toc/1476-511X

Access URL: https://doaj.org/article/4d9bf9c18f6f41499b6b70bf0e68e597

CTHRC1+ fibroblasts are stimulated by macrophage‐secreted SPP1 to induce excessive collagen deposition in keloids

Authors: Jing Liu, Yan Huang, Yiyi Gong, Qingmei Liu, Jinran Lin, Jianlan Liu, Mengguo Liu, Jia Huang, Weilin Pu, Yanyun Ma, Yuting Zhang, Haiyang Li, Xiangguang Shi, Yue Zhang, Jian Wang, Yifei Zhu, Qin Wang, Kelu Wei, Jiayi Wang, Yu'ou Sha, Jiucun Wang, Wenyu Wu

Source: Clinical and Translational Medicine, Vol 12, Iss 12, Pp n/a-n/a (2022)

Subject Terms: Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2001-1326

Access URL: https://doaj.org/article/edf680eb8f724045a732fa74a71fd8dc

LDLR dysfunction induces LDL accumulation and promotes pulmonary fibrosis

Authors: Xiangguang Shi, Yahui Chen, Qingmei Liu, Xueqian Mei, Jing Liu, Yulong Tang, Ruoyu Luo, Dayan Sun, Yanyun Ma, Wenyu Wu, Wenzhen Tu, Yinhuan Zhao, Weihong Xu, Yuehai Ke, Shuai Jiang, Yan Huang, Rui Zhang, Lei Wang, Yuanyuan Chen, Jingjing Xia, Weilin Pu, Honglin Zhu, Xiaoxia Zuo, Yisha Li, Jinhua Xu, Fei Gao, Dong Wei, Jingyu Chen, Wenguang Yin, Qingwen Wang, Huaping Dai, Libing Yang, Gang Guo, Jimin Cui, Nana Song, Hejian Zou, Shimin Zhao, Jörg H.W. Distler, Li Jin, Jiucun Wang

Source: Clinical and Translational Medicine, Vol 12, Iss 1, Pp n/a-n/a (2022)

Subject Terms: apoptosis, combination treatment, LDL, LDLR, pulmonary fibrosis, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2001-1326

Access URL: https://doaj.org/article/0f21d675bca543928fd4910c62714fc6

Increased Expression of Zyxin and Its Potential Function in Androgenetic Alopecia

Authors: Qingmei Liu, Xiangguang Shi, Yue Zhang, Yan Huang, Kai Yang, Yulong Tang, Yanyun Ma, Yuting Zhang, Ji'an Wang, Li Zhang, Qi Zhang, Xiao Liu, Jinran Lin, Jiucun Wang, Wenyu Wu

Source: Frontiers in Cell and Developmental Biology, Vol 8 (2021)

Subject Terms: androgenetic alopecia, Zyxin, hair follicle, dermal papilla cell, RNA-seq, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2020.582282/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/b79af1202ba64c60a68dee9eeda55de4

Treatment effects of the traditional Chinese medicine Shenks in bleomycin-induced lung fibrosis through regulation of TGF-beta/Smad3 signaling and oxidative stress

Authors: Haiyan Chu, Ying Shi, Shuai Jiang, Qicheng Zhong, Yongqiang Zhao, Qingmei Liu, Yanyun Ma, Xiangguang Shi, Weifeng Ding, Xiaodong Zhou, Jimin Cui, Li Jin, Gang Guo, Jiucun Wang

Source: Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/0facbc85898245e5ac42ab18e616186d

Enhancement of Zyxin Promotes Skin Fibrosis by Regulating FAK/PI3K/AKT and TGF-β Signaling Pathways via Integrins.

Authors: Yan Huang, Han Zhao, Yuting Zhang, Yulong Tang, Xiangguang Shi, Shuai Jiang, Weilin Pu, Jing Liu, Yanyun Ma, Juiming Lin, Jinran Lin, Wenyu Wu, Yiyi Gong, Jiucun Wang, Qingmei Liu

Source: International Journal of Biological Sciences; 2023, Vol. 19 Issue 8, p2394-2408, 15p

Sirtuin1 Protects against Systemic Sclerosis-related Pulmonary Fibrosis by Decreasing Proinflammatory and Profibrotic Processes.

Authors: Haiyan Chu, Shuai Jiang, Qingmei Liu, Yanyun Ma, Xiaoxia Zhu, Minrui Liang, Xiangguang Shi, Weifeng Ding, Xiaodong Zhou, Hejian Zou, Feng Qian, Shaul, Philip W., Li Jin, Jiucun Wang

Source: American Journal of Respiratory Cell & Molecular Biology; Jan2018, Vol. 58 Issue 1, p28-39, 12p, 6 Graphs

Glycolytic reprogramming in cancer cells: PKM2 dimer predominance induced by pulsatile PFK-1 activity.

Authors: Xiangguang Shi, Lingchong You, Ruo-yu Luo

Source: Physical Biology; Nov2019, Vol. 16 Issue 6, p1-1, 1p

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