D-ribose-5-phosphate inactivates YAP and functions as a metabolic checkpoint

Authors: Cheng-E Tu, Yong-Feng Liu, Hong-Wei Liu, Chun-Mei Jiao, Quentin Liu, Mien-Chie Hung, Peng Li, Xiang-Bo Wan, Xin-Juan Fan, Yun-Long Wang

Source: Journal of Hematology & Oncology, Vol 18, Iss 1, Pp 1-21 (2025)

Subject Terms: Metabolic stress, Glucose deprivation, D-ribose-5-phosphate, YAP, LATS1, Purine nucleoside phosphorylase, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-8722

Access URL: https://doaj.org/article/0a960a347acd48219c9586a2b7e46cf6

Phase separation in DNA double-strand break response

Authors: Huan-Lei Liu, Hao Nan, Wan-Wen Zhao, Xiang-Bo Wan, Xin-Juan Fan

Source: Nucleus, Vol 15, Iss 1 (2024)

Subject Terms: DNA damage response (DDR), DNA double-strand break (DSB), liquid-liquid phase separation (LLPS), condensates, homologous recombination (HR), nonhomologous end-joining (NHEJ), Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1949-1034; https://doaj.org/toc/1949-1042

Access URL: https://doaj.org/article/7751d5556522435ca788274cdf66af7c

Liquid-liquid phase separation in DNA double-strand breaks repair

Authors: Yun-Long Wang, Wan-Wen Zhao, Jie Shi, Xiang-Bo Wan, Jian Zheng, Xin-Juan Fan

Source: Cell Death and Disease, Vol 14, Iss 11, Pp 1-10 (2023)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/37087f77236f482fb697648277d8055a

Effects of neoadjuvant radiochemotherapy for anorectal function in locally advanced rectal cancer patients: a study protocol for a prospective, observational, controlled, multicentre study

Authors: Jie Shi, Yi-Kan Cheng, Fang He, Jian Zheng, Yun-Long Wang, Xiang-Bo Wan, Hong-Cheng Lin, Xin-Juan Fan

Source: BMC Cancer, Vol 23, Iss 1, Pp 1-7 (2023)

Subject Terms: Anorectal function, Locally advanced rectal cancer, Neoadjuvant chemoradiotherapy, Total mesorectal excision, Sphincter preservation treatments, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/7b4c858db413410ab17621da85345ea7

CiRS-7 Enhances the Liquid-liquid Phase Separation of miRISC and Promotes DNA Damage Repair

Authors: Yun-Long Wang, Li-Li Feng, Jie Shi, Wan-Ying Chen, Shu-Ying Bie, Shao-Mei Bai, Guang-Dong Zeng, Rui-Zhi Wang, Jian Zheng, Xiang-Bo Wan, Xin-Juan Fan

Source: Nucleus, Vol 14, Iss 1 (2023)

Subject Terms: CircRNA, ciRS-7, condensation, DNA repair, liquid-liquid phase separation, miRISC, Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1949-1034; https://doaj.org/toc/1949-1042

Access URL: https://doaj.org/article/bee520bfbc00401088b402ce11f3625a

DNA damage-induced paraspeckle formation enhances DNA repair and tumor radioresistance by recruiting ribosomal protein P0

Authors: Yun-Long Wang, Wan-Wen Zhao, Shao-Mei Bai, Yan Ma, Xin-Ke Yin, Li-Li Feng, Guang-Dong Zeng, Fang Wang, Wei-Xing Feng, Jian Zheng, Ying-Nai Wang, Bing Zeng, Quentin Liu, Mien-Chie Hung, Xiang-Bo Wan

Source: Cell Death and Disease, Vol 13, Iss 8, Pp 1-13 (2022)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/67b2f196f89c4d2e98e308070287c485

MRNIP condensates promote DNA double-strand break sensing and end resection

Authors: Yun-Long Wang, Wan-Wen Zhao, Shao-Mei Bai, Li-Li Feng, Shu-Ying Bie, Li Gong, Fang Wang, Ming-Biao Wei, Wei-Xing Feng, Xiao-Lin Pang, Cao-Litao Qin, Xin-Ke Yin, Ying-Nai Wang, Weihua Zhou, Daniel R. Wahl, Quentin Liu, Ming Chen, Mien-Chie Hung, Xiang-Bo Wan

Source: Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/0d2d630dc0a747b8807be46604e76da1

Fibroblast CEBPD/SDF4 axis in response to chemotherapy-induced angiogenesis through CXCR4

Authors: Jhih-Ying Chi, Yu-Wei Hsiao, Hai-Ling Liu, Xin-Juan Fan, Xiang-Bo Wan, Tsung-Lin Liu, Sheng-Jou Hung, Yi-Ting Chen, Hsin-Yin Liang, Ju-Ming Wang

Source: Cell Death Discovery, Vol 7, Iss 1, Pp 1-16 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2058-7716

Access URL: https://doaj.org/article/757da9e997c74013b8992407199a400b

The watch-and-wait strategy versus surgical resection for rectal cancer patients with a clinical complete response after neoadjuvant chemoradiotherapy

Authors: Qiao-xuan Wang, Rong Zhang, Wei-wei Xiao, Shu Zhang, Ming-biao Wei, Yong-heng Li, Hui Chang, Wei-hao Xie, Li-ren Li, Pei-rong Ding, Gong Chen, Zhi-fan Zeng, Wei-hu Wang, Xiang-bo Wan, Yuan-hong Gao

Source: Radiation Oncology, Vol 16, Iss 1, Pp 1-8 (2021)

Subject Terms: Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1748-717X

Access URL: https://doaj.org/article/babda910c4bb48308aaf8a3cb193ba1f

A circRNA signature predicts postoperative recurrence in stage II/III colon cancer

Authors: Huai‐Qiang Ju, Qi Zhao, Feng Wang, Ping Lan, Zixian Wang, Zhi‐Xiang Zuo, Qi‐Nian Wu, Xin‐Juan Fan, Hai‐Yu Mo, Li Chen, Ting Li, Chao Ren, Xiang‐Bo Wan, Gong Chen, Yu‐Hong Li, Wei‐Hua Jia, Rui‐Hua Xu

Source: EMBO Molecular Medicine, Vol 11, Iss 10, Pp 1-13 (2019)

Subject Terms: biomarker, circular RNA, recurrence, stage II/III colon cancer, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/94e8fd3a10b94556b180eefd64ab1aa9

Prognostic Value of Interval Between the Initiation of Neoadjuvant Treatment to Surgery for Patients With Locally Advanced Rectal Cancer Following Neoadjuvant Chemotherapy, Radiotherapy and Definitive Surgery

Authors: Xiang-Bo Wan, Qun Zhang, Mo Chen, Yanping Liu, Jian Zheng, Ping Lan, Fang He

Source: Frontiers in Oncology, Vol 10 (2020)

Subject Terms: locally advanced rectal cancer, neoadjuvant treatment, neoadjuvant treatment interval, prognostic value, surgery interval, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fonc.2020.01280/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/0ef522fa10a14ccc85b06746b78a024b

Endoscope-guided interstitial intensity-modulated brachytherapy and intracavitary brachytherapy as boost radiation for primary early T stage nasopharyngeal carcinoma.

Authors: Xiang-Bo Wan, Rou Jiang, Fang-Yun Xie, Zhen-Yu Qi, Ai-Ju Li, Wei-Jun Ye, Yi-Jun Hua, Yu-Liang Zhu, Xiong Zou, Ling Guo, Hai-Qiang Mai, Xiang Guo, Ming-Huang Hong, Ming-Yuan Chen

Source: PLoS ONE, Vol 9, Iss 3, p e90048 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090048&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/1ffea6896a2146068bb22cd6b01373af

Beclin 1 deficiency correlated with lymph node metastasis, predicts a distinct outcome in intrahepatic and extrahepatic cholangiocarcinoma.

Authors: Tian-Tian Wang, Qing-Hua Cao, Ming-Yuan Chen, Qing Xia, Xin-Juan Fan, Xiao-Kun Ma, Qu Lin, Chang-Chang Jia, Min Dong, Dan-Yun Ruan, Ze-Xiao Lin, Jing-Yun Wen, Li Wei, Xing Li, Zhan-Hong Chen, Lei Wang, Xiang-Yuan Wu, Xiang-Bo Wan

Source: PLoS ONE, Vol 8, Iss 11, p e80317 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3841169?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/adc78059c4f140c09588ea933c85aa77

Molecular prognostic prediction for locally advanced nasopharyngeal carcinoma by support vector machine integrated approach.

Authors: Xiang-Bo Wan, Yan Zhao, Xin-Juan Fan, Hong-Min Cai, Yan Zhang, Ming-Yuan Chen, Jie Xu, Xiang-Yuan Wu, Hong-Bo Li, Yi-Xin Zeng, Ming-Huang Hong, Quentin Liu

Source: PLoS ONE, Vol 7, Iss 3, p e31989 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3302890?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/cac1826dd0ba444db61a9b616f7bc7f2

Ubiquitin-induced RNF168 condensation promotes DNA double-strand break repair.

Authors: Li-Li Feng, Shu-Ying Bie, Zhi-Heng Deng, Shao-Mei Bai, Jie Shi, Cao-Litao Qin, Huan-Lei Liu, Jia-Xu Li, Wan-Ying Chen, Jin-Ying Zhou, Chun-Mei Jiao, Yi Ma, Meng-Bo Qiu, Hua-Song Ai, Jian Zheng, Mien-Chie Hung, Yun-Long Wang, Xiang-Bo Wan, Xin-Juan Fan

Source: Proceedings of the National Academy of Sciences of the United States of America; 7/9/2024, Vol. 121 Issue 28, p1-11, 29p

Subject Terms: DOUBLE-strand DNA breaks, DNA condensation, DNA repair, PHASE separation, CATALYTIC activity

Comparison of clinicopathologic parameters and oncologic outcomes between type 1 and type 2 papillary renal cell carcinoma

Authors: Xiang Le, Xiang-Bo Wang, Hao Zhao, Ren-Fu Chen, Peng Ge

Source: BMC Urology, Vol 20, Iss 1, Pp 1-7 (2020)

Subject Terms: Papillary renal cell carcinoma, WHO/ISUP grade, Prognosis, Subtype, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12894-020-00716-0; https://doaj.org/toc/1471-2490

Access URL: https://doaj.org/article/63d785cb7dfc4969a296cfa2977aed4d

Feedback Control for Passivity of Memristor-Based Multiple Weighted Coupled Neural Networks

Authors: Xiang-Bo Wang, Hong-An Tang, Qingling Xia, Quanjun Zhao, Gang-Yi Tan

Source: Discrete Dynamics in Nature and Society, Vol 2022 (2022)

Subject Terms: Mathematics, QA1-939

File Description: electronic resource

Relation: https://doaj.org/toc/1607-887X

Access URL: https://doaj.org/article/61fd56d01800491399cc09a597635c94

Aberrant expression of enhancer of zeste homologue 2, correlated with HIF-1α, refines relapse risk and predicts poor outcome for breast cancer.

Authors: MIN DONG, XIN-JUAN FAN, ZHAN-HONG CHEN, TIAN-TIAN WANG, XING LI, JIE CHEN, QU LIN, JING-YUN WEN, XIAO-KUN MA, LI WEI, DAN-YUN RUAN, ZE-XIAO LIN, QUENTIN LIU, XIANG-YUAN WU, XIANG-BO WAN

Source: Oncology Reports; 2014, Vol. 32 Issue 3, p1101-1107, 7p

Snail promotes lymph node metastasis and Twist enhances tumor deposit formation through epithelial-mesenchymal transition in colorectal cancer.

Authors: Xin-Juan Fan, Xiang-Bo Wan, Zu-Li Yang, Xin-Hui Fu, Yan Huang, Dian-Ke Chen, Shun-Xin Song, Quentin Liu, Huan-Yu Xiao, Lei Wang, Jian-Ping Wang

Source: Human Pathology; 2013, Vol. 44 Issue 2, p173-180, 8p

Subject Terms: GENETIC repressors, CADHERINS, IMMUNOHISTOCHEMISTRY, COLON cancer, LOGISTIC regression analysis, CELLULAR signal transduction

Low expression of Beclin 1, associated with high Bcl-xL, predicts a malignant phenotype and poor prognosis of gastric cancer.

Authors: Wei-Hua Zhou, Fang Tang, Jie Xu, Xing Wu, Shao-Bing Yang, Zhi-Ying Feng, Yun-Gang Ding, Xiang-Bo Wan, Zhong Guan, Hai-Gang Li, Dong-Jun Lin, Chun-Kui Shao, Quentin Liu

Source: Autophagy; Mar2012, Vol. 8 Issue 3, p389-400, 12p