Are mRNA based transcriptomic signatures ready for diagnosing tuberculosis in the clinic? - A review of evidence and the technological landscape

Authors: Hamada, Yohhei, Penn-Nicholson, Adam, Krishnan, Sriram, Cirillo, Daniela Maria, Matteelli, Alberto, Wyss, Romain, Denkinger, Claudia M., Rangaka, Molebogeng X., Ruhwald, Morten, Schumacher, Samuel G.

Source: In eBioMedicine August 2022 82

Expression, Biochemistry, and Stabilization with Camel Antibodies of Membrane Proteins: Case Study of the Mouse 5-HT3 Receptor

Authors: Hassaïne, Ghérici, Deluz, Cédric, Grasso, Luigino, Wyss, Romain, Hovius, Ruud, Stahlberg, Henning, Tomizaki, Takashi, Desmyter, Aline, Moreau, Christophe, Peclinovska, Lucie

Source: Methods in molecular biology. 1635:139-168

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN612417349&indx=1&recIds=ETOCRN612417349

Evaluation of the diagnostic performance of laboratory-based c-reactive protein as a triage test for active pulmonary tuberculosis.

Authors: Samuels, Thomas H. A.^1,2 (AUTHOR), Wyss, Romain³ (AUTHOR), Ongarello, Stefano³ (AUTHOR), Moore, David A. J.^1,2 (AUTHOR), Schumacher, Samuel G.³ (AUTHOR) samuel.schumacher@finddx.org, Denkinger, Claudia M.³ (AUTHOR)

Source: PLoS ONE. 7/12/2021, Vol. 16 Issue 7, p1-15. 15p.

Subject Terms: *C-reactive protein, *TUBERCULOSIS, *MEDICAL triage, *RECEIVER operating characteristic curves, *ADULTS, *ALGORITHMS

Geographic Terms: GEORGIA (Republic), PERU, VIETNAM

Effects of a milk oligosaccharide biosimilar on fecal characteristics, microbiota, and bile acid, calprotectin, and immunoglobulin concentrations of healthy adult dogs treated with metronidazole.

Authors: Belchik, Sara E, Oba, Patricia M, Wyss, Romain, Asare, Paul T, Vidal, Sara, Miao, Yong, Adesokan, Yemi, Suchodolski, Jan S, Swanson, Kelly S

Source: Journal of Animal Science; Jan2023, Vol. 101 Issue 1, p1-14, 14p

Subject Terms: CALPROTECTIN, BILE acids, FEMALE dogs, OLIGOSACCHARIDES, METRONIDAZOLE, DNA sequencing, DOGS, GUT microbiome, ENTEROHEPATIC circulation

Molecular screening of cancer-derived exosomes by surface plasmon resonance spectroscopy.

Authors: Grasso, Luigino¹, Wyss, Romain¹, Weidenauer, Lorenz¹, Thampi, Ashwin¹, Demurtas, Davide², Prudent, Michel³, Lion, Niels³, Vogel, Horst¹ horst.vogel@epfl.ch

Source: Analytical & Bioanalytical Chemistry. Jul2015, Vol. 407 Issue 18, p5425-5432. 8p.

Subject Terms: *EXOSOMES, *SURFACE plasmon resonance, *CANCER research, *BLOOD, *BIOMARKERS, *MEDICAL screening

A Quantitative Approach to Evaluate the Impact of Fluorescent Labeling on Membrane-Bound HIV-Gag Assembly by Titration of Unlabeled Proteins.

Authors: Gunzenhäuser, Julia¹, Wyss, Romain², Manley, Suliana¹

Source: PLoS ONE. Dec2014, Vol. 9 Issue 12, p1-18. 18p.

Subject Terms: *FLUORESCENCE, *HIV infections, *GAG proteins, *VOLUMETRIC analysis, *VIRAL proteins, *MICROSCOPY

A novel blood-based assay for treatment monitoring of tuberculosis.

Authors: Zimmer, Alexandra J., Schumacher, Samuel G., Södersten, Erik, Mantsoki, Anna, Wyss, Romain, Persing, David H., Banderby, Sara, Strömqvist Meuzelaar, Linda, Prieto, Jacqueline, Gnanashanmugam, Devasena, Khatri, Purvesh, Ongarello, Stefano, Ruhwald, Morten, Denkinger, Claudia M.

Source: BMC Research Notes; 6/30/2021, Vol. 14, p1-5, 5p

Subject Terms: TUBERCULOSIS, RNA sequencing, THERAPEUTICS

Downscaling the Analysis of Complex Transmembrane Signaling Cascades to Closed Attoliter Volumes.

Authors: Grasso, Luigino¹, Wyss, Romain¹, Piguet, Joachim¹, Werner, Michael¹, Hassaïne, Ghérici¹, Hovius, Ruud¹, Vogel, Horst¹ Horst.Vogel@epfl.ch

Source: PLoS ONE. Aug2013, Vol. 8 Issue 8, p1-9. 9p.

Subject Terms: *CELLULAR signal transduction, *OPTICAL properties, *ELECTRIC properties of cells, *CELL membranes, *MOLECULAR biology, *CYTOCHEMISTRY

Effect of a novel animal milk oligosaccharide biosimilar on macronutrient digestibility and gastrointestinal tolerance, fecal metabolites, and fecal microbiota of healthy adult cats.

Authors: Oba, Patrícia M, Lee, Anne H, Vidal, Sara, Wyss, Romain, Miao, Yong, Adesokan, Yemi, Swanson, Kelly S

Source: Journal of Animal Science; Jan2021, Vol. 99 Issue 1, p1-15, 15p

Subject Terms: FECES, SHORT-chain fatty acids, IMMUNOGLOBULIN A, CATS, METABOLITES, INGESTION

Effect of a novel animal milk oligosaccharide biosimilar on the gut microbial communities and metabolites of in vitro incubations using feline and canine fecal inocula.

Authors: Oba, Patrícia M., Vidal, Sara, Wyss, Romain, Yong Miao, Adesokan, Yemi, Swanson, Kelly S.

Source: Journal of Animal Science; Sep2020, Vol. 98 Issue 9, p1-11, 11p, 3 Charts, 2 Graphs

Spontaneous Cdc42 Polarization Independent of GDI-Mediated Extraction and Actin-Based Trafficking.

Authors: Bendezú, Felipe O.¹, Vincenzetti, Vincent¹, Vavylonis, Dimitrios², Wyss, Romain³, Vogel, Horst³, Martin, Sophie G.¹, Sophie.Martin@unil.ch

Source: PLoS Biology; Apr2015, Vol. 13 Issue 4, p1-30, 30p

X-ray structure of the mouse serotonin 5-HT3 receptor.

Authors: Hassaine, Ghérici, Deluz, Cédric, Grasso, Luigino, Wyss, Romain, Tol, Menno B., Hovius, Ruud, Graff, Alexandra, Stahlberg, Henning, Tomizaki, Takashi, Desmyter, Aline, Moreau, Christophe, Li, Xiao-Dan, Poitevin, Frédéric, Vogel, Horst, Nury, Hugues

Source: Nature. 8/21/2014, Vol. 512 Issue 7514, p276-281. 6p.

Subjects: X-ray imaging, SEROTONIN receptors, NEUROTRANSMITTERS, ION channels, NEURAL transmission, LABORATORY mice

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A multi-targeted T-cell engagement of PD1-resistant colorectal cancer cells via delivery of glycopeptide conjugates.

Authors: Adesokan, Yemi, Schwarzfischer, Marlene, Wyss, Romain, Miao, Yong, Asare, Paul, Spalinger, Marianne Rebecca, Scharl, Michael

Source: Journal of Clinical Oncology; 2023 Supplement 16, Vol. 41, pe14571-e14571, 1p

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Expression, Purification and Stabilization of the Mouse 5HT3 Receptor

Authors: Hassaine, Gherici, Deluz, Cedric, Graff, Alexandra, Moreau, Christophe, Wyss, Romain, Grasso, Luigino, Desmyter, Aline, Tomizaki, Takashi, Li, Xiao-Dan, Stahlberg, Henning, Vogel, Horst, Nury, Hugues

Source: In Biophysical Journal 28 January 2014 106(2) Supplement 1:338a-338a

Revealing the Impact of Fluorescent Labeling on HIV-Gag Virus-Like Particle Formation by Quantitative Super-Resolution Imaging and Fluorescence Correlation Spectroscopy

Authors: Gunzenhäuser, Julia, Olivier, Nicolas, Pengo, Thomas, Wyss, Romain, Benadiba, Carine, Manley, Suliana

Source: In Biophysical Journal 29 January 2013 104(2) Supplement 1:416a-416a

Subwavelength Metal Apertures for Label-Free Detection of Single-Molecules

Authors: Wyss, Romain, Sandén, Tor, Piguet, Joachim, Santschi, Christian, Hassaïne, Ghérici, Deluz, Cédric, Martin, Olivier J.F., Wennmalm, Stefan, Vogel, Horst

Source: In Biophysical Journal 31 January 2012 102(3) Supplement 1:727a-727a