Molecular Biomarkers Associated with Traumatic Brain Injury Outcome in Individuals of Black Racial Identity or African Ancestry: A Narrative Review

Authors: Wroblewski, Tadeusz H. ^{1, 2, 3}, Ajmal, Erum ^{1, 2}, Ononogbu-Uche, Favour ^{1, 2}, Lerner, David P. ^{4, 5}, Bigdeli, Tim B. ^{6, 7, 8, 9}, Divers, Jasmin ¹⁰, Barthélemy, Ernest J. ^{1, 2, 4, 5, 7, 11, 12, 13, ∗}

Source: In World Neurosurgery February 2025 194

Radiomic Consensus Clustering in Glioblastoma and Association with Gene Expression Profiles.

Authors: Wroblewski, Tadeusz H.^1,2 (AUTHOR) tadeusz.wroblewski@downstate.edu, Karabacak, Mert³ (AUTHOR) mert.karabacak@mountsinai.org, Seah, Carina⁴ (AUTHOR) carina.seah@icahn.mssm.edu, Yong, Raymund L.³ (AUTHOR) raymund.yong@mountsinai.org, Margetis, Konstantinos³ (AUTHOR) konstantinos.margetis@mountsinai.org

Source: Cancers. Dec2024, Vol. 16 Issue 24, p4256. 13p.

Subject Terms: *CONSENSUS (Social sciences), *DISEASE clusters, *GLIOMAS, *RADIOMICS, *KRUSKAL-Wallis Test, *FISHER exact test, *DESCRIPTIVE statistics, *MAGNETIC resonance imaging, *GENE expression profiling, *MACHINE learning, *DATA analysis software

Self-inflicted bilateral penetrating brain injury with a nail gun in an African American male: illustrative case.

Authors: Schultz, Aaliyah, Wroblewski, Tadeusz H., Ononogbu-Uche, Favour C., Asfaw, Zerubabbel K., Lerner, David P., Roberts, Marie-Claire, Bigdeli, Tim B., Barthélemy, Ernest J.

Source: Journal of Neurosurgery Case Lessons; Feb2025, Vol. 9 Issue 6, p1-10, 10p

Targeting DNA Methyl Transferases with Decitabine in Cultured Meningiomas

Authors: Tatman, Philip D., Wroblewski, Tadeusz H., Fringuello, Anthony R., Scherer, Samuel R., Foreman, William B., Damek, Denise M., Lillehei, Kevin O., Jensen, Randy L., Youssef, A. Samy, Ormond, D. Ryan, Graner, Michael W.

Source: World neurosurgery. 162:e99-e119

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100180333276.0x000001&indx=1&recIds=ETOCvdc_100180333276.0x000001

Pharmacogenetic Variation in Neanderthals and Denisovans and Implications for Human Health and Response to Medications.

Authors: Wroblewski, Tadeusz H¹ (AUTHOR), Witt, Kelsey E² (AUTHOR), Lee, Seung-been³ (AUTHOR), Malhi, Ripan S⁴ (AUTHOR), Peede, David^5,6 (AUTHOR), Huerta-Sánchez, Emilia⁵ (AUTHOR), Villanea, Fernando A⁷ (AUTHOR) Fernando.Villanea@colorado.edu, Claw, Katrina G¹ (AUTHOR) Fernando.Villanea@colorado.edu

Source: Genome Biology & Evolution. Dec2023, Vol. 15 Issue 12, p1-20. 20p.

Subject Terms: *DENISOVANS, *NEANDERTHALS, *SINGLE nucleotide polymorphisms, *PHARMACOGENOMICS, *CHROMOSOME duplication, *CYTOCHROME P-450, *CYTOCHROME c

G‐Quadruplexes act as sequence‐dependent protein chaperones

Authors: Begeman, Adam, Son, Ahyun, Litberg, Theodore J, Wroblewski, Tadeusz H, Gehring, Thane, Huizar Cabral, Veronica, Bourne, Jennifer, Xuan, Zhenyu, Horowitz, Scott

Source: EMBO reports. 21(10)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128296822.0x000001&indx=1&recIds=ETOCvdc_100128296822.0x000001

High-Throughput Screening of Epigenetic Inhibitors in Meningiomas Identifies HDAC, G9a, and Jumonji-Domain Inhibition as Potential Therapies.

Authors: Tatman, Philip D.^1,2,3 (AUTHOR), Wroblewski, Tadeusz H.^1,4 (AUTHOR), Fringuello, Anthony R.¹ (AUTHOR), Scherer, Samuel R.^1,4 (AUTHOR), Foreman, William B.^1,4 (AUTHOR), Damek, Denise M.⁴ (AUTHOR), Youssef, A. Samy¹ (AUTHOR), Lillehei, Kevin O.¹ (AUTHOR), Jensen, Randy L.⁵ (AUTHOR), Graner, Michael W.¹ (AUTHOR) michael.graner@cuanschutz.edu, Ormond, D. Ryan¹ (AUTHOR)

Source: Journal of Neurological Surgery. Part B. Skull Base. Oct2023, Vol. 84 Issue 5, p452-462. 11p.

Subject Terms: *HIGH throughput screening (Drug development), *EPIGENETICS, *HISTONE deacetylase inhibitors, *CELL survival, *TUMOR grading

High-Throughput Mechanistic Screening of Epigenetic Compounds for the Potential Treatment of Meningiomas.

Authors: Tatman, Philip D.^1,2,3 (AUTHOR) philip.tatman@cuanschutz.edu, Wroblewski, Tadeusz H.^1,4 (AUTHOR) tadeusz.wroblewski@cuanschutz.edu, Fringuello, Anthony R.¹ (AUTHOR) anthonyfringuello@gmail.com, Scherer, Samuel R.^1,4 (AUTHOR) samuelrscherer@gmail.com, Foreman, William B.^1,4 (AUTHOR) will.b.foreman@outlook.com, Damek, Denise M.^1,4 (AUTHOR) DENISE.DAMEK@CUANSCHUTZ.EDU, Lillehei, Kevin¹ (AUTHOR) KEVIN.LILLEHEI@CUANSCHUTZ.EDU, Youssef, A. Samy¹ (AUTHOR) SAMY.YOUSSEF@CUANSCHUTZ.EDU, Jensen, Randy L.⁵ (AUTHOR) Randy.Jensen@hsc.utah.edu, Graner, Michael W.¹ (AUTHOR) michael.graner@cuanschutz.edu, Ormond, D. Ryan¹ (AUTHOR) michael.graner@cuanschutz.edu

Source: Journal of Clinical Medicine. Jul2021, Vol. 10 Issue 14, p3150-3150. 1p.

Subject Terms: *HIGH throughput screening (Drug development), *HISTONE deacetylase, *EPIGENETICS, *HISTONE deacetylase inhibitors, *PROGNOSIS, CENTRAL nervous system tumors

Company/Entity: UNITED States. Food & Drug Administration