Development and evaluation of nanobody tracers for noninvasive nuclear imaging of the immune-checkpoint TIGIT

Authors: Katty Zeven, Timo W.M. De Groof, Hannelore Ceuppens, Robin Maximilian Awad, Thomas Ertveldt, Wout de Mey, Fien Meeus, Geert Raes, Karine Breckpot, Nick Devoogdt

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: TIGIT, immune checkpoint (ICP), nuclear imaging, noninvasive diagnosis, tracer development, nanobodies, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1268900/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/051a7b27d7524e158560ba763978542a

An mRNA mix redirects dendritic cells towards an antiviral program, inducing anticancer cytotoxic stem cell and central memory CD8+ T cells

Authors: Wout de Mey, Hanne Locy, Kirsten De Ridder, Phaedra De Schrijver, Dorien Autaers, Asma Lakdimi, Arthur Esprit, Lorenzo Franceschini, Kris Thielemans, Magali Verdonck, Karine Breckpot

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: cancer, CD40 ligand, dendritic cell, interferon-gamma, interleukin-10, interleukin-12, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1111523/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/e9862a7e26b048f78a167d94669c00a0

TNF-α-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 Immunotherapy

Authors: Kirsten De Ridder, Hanne Locy, Elisa Piccioni, Miren Ibarra Zuazo, Robin Maximilian Awad, Stefaan Verhulst, Mathias Van Bulck, Yannick De Vlaeminck, Quentin Lecocq, Eva Reijmen, Wout De Mey, Lien De Beck, Thomas Ertveldt, Isabel Pintelon, Jean-Pierre Timmermans, David Escors, Marleen Keyaerts, Karine Breckpot, Cleo Goyvaerts

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: anti-PD-L1 immunotherapy, non small cell lung cancer (NSCLC), tumor-infiltrating myeloid cells, TNF-α, immunotherapy resistance, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.811867/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/8cb0f64de304414d9efd07fa0701e7a3

Neo-Antigen mRNA Vaccines

Authors: Arthur Esprit, Wout de Mey, Rajendra Bahadur Shahi, Kris Thielemans, Lorenzo Franceschini, Karine Breckpot

Source: Vaccines, Vol 8, Iss 4, p 776 (2020)

Subject Terms: cancer, neo-antigen, mRNA, vaccine, dendritic cell, T cell, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/8/4/776; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/bdd762e0a07a4578bec1480790bd1414

Immunomodulation of the Tumor Microenvironment: Turn Foe Into Friend

Authors: Hanne Locy, Sven de Mey, Wout de Mey, Mark De Ridder, Kris Thielemans, Sarah K. Maenhout

Source: Frontiers in Immunology, Vol 9 (2018)

Subject Terms: immunotherapy, oncolytic virotherapy, radiotherapy, cancer, in situ vaccination, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2018.02909/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/3b78802ee8044633847a98bb92eb647b