Serum Metabolomic Markers of Artificially Sweetened Beverage Consumption

Authors: Jia, Hejingzi, Bernard, Lauren, Chen, Jingsha, Du, Shutong, Steffen, Lyn M, Wong, Kari E, Yu, Bing, Sullivan, Valerie K, Rebholz, Casey M

Source: In The Journal of Nutrition November 2024 154(11):3266-3273

Serum Metabolomic Markers of Protein-Rich Foods and Incident CKD: Results From the Atherosclerosis Risk in Communities Study

Authors: Bernard, Lauren, Chen, Jingsha, Kim, Hyunju, Wong, Kari E., Steffen, Lyn M., Yu, Bing, Boerwinkle, Eric, Levey, Andrew S., Grams, Morgan E., Rhee, Eugene P., Rebholz, Casey M.

Source: In Kidney Medicine April 2024 6(4)

Serum Metabolomic Markers of Dairy Consumption: Results from the Atherosclerosis Risk in Communities Study and the Bogalusa Heart Study

Authors: Bernard, Lauren, Chen, Jingsha, Kim, Hyunju, Huang, Zhijie, Bazzano, Lydia, Qi, Lu, He, Jiang, Rao, Varun S., Potts, Kaitlin S., Kelly, Tanika N., Wong, Kari E., Steffen, Lyn M., Yu, Bing, Rhee, Eugene P., Rebholz, Casey M.

Source: In The Journal of Nutrition October 2023 153(10):2994-3002

Metabolomics of Dietary Intake of Total, Animal, and Plant Protein: Results from the Atherosclerosis Risk in Communities (ARIC) Study

Authors: Bernard, Lauren, Chen, Jingsha, Kim, Hyunju, Wong, Kari E., Steffen, Lyn M., Yu, Bing, Boerwinkle, Eric, Rebholz, Casey M.

Source: In Current Developments in Nutrition April 2023 7(4)

Serum metabolomic signatures of plant-based diets and incident chronic kidney disease

Authors: Kim, Hyunju, Yu, Bing, Li, Xin, Wong, Kari E, Boerwinkle, Eric, Seidelmann, Sara B, Levey, Andrew S, Rhee, Eugene P, Coresh, Josef, Rebholz, Casey M ^*

Source: In The American Journal of Clinical Nutrition July 2022 116(1):151-164

Multifluid Metabolomics Identifies Novel Biomarkers for Irritable Bowel Syndrome.

Authors: Kirk, Daniel, Louca, Panayiotis, Attaye, Ilias, Zhang, Xinyuan, Wong, Kari E., Michelotti, Gregory A., Falchi, Mario, Valdes, Ana M., Williams, Frances M. K., Menni, Cristina

Source: Metabolites (2218-1989); Feb2025, Vol. 15 Issue 2, p121, 17p

Subject Terms: IRRITABLE colon, XENOBIOTICS, METABOLOMICS, METABOLITES, STEROID hormones

Serum metabolite signature of the modified Mediterranean-DASH intervention for neurodegenerative delay (MIND) diet.

Authors: Yang, Jiaqi, Bernard, Lauren, Wong, Kari E., Yu, Bing, Steffen, Lyn M., Sullivan, Valerie K., Rebholz, Casey M.

Source: Metabolomics; Dec2024, Vol. 20 Issue 6, p1-13, 13p

Subject Terms: DIETARY patterns, BONFERRONI correction, OLIVE oil, XENOBIOTICS, REGRESSION analysis

Increased Plasma Branched Short-Chain Fatty Acids and Improved Glucose Homeostasis: The Microbiome and Insulin Longitudinal Evaluation Study (MILES).

Authors: Aslamy, Arianne, Wood, Alexis C., Jensen, Elizabeth T., Bertoni, Alain G., Sheridan, Patricia A., Wong, Kari E., Ramesh, Gautam, Rotter, Jerome I., Chen, Yii-Der I., Goodarzi, Mark O.

Source: Diabetes; Mar2024, Vol. 73 Issue 3, p385-390, 6p

Subject Terms: SHORT-chain fatty acids, GLUCOSE, HOMEOSTASIS, INSULIN, INSULIN sensitivity, PAIN tolerance

Carnitine Acetyltransferase Mitigates Metabolic Inertia and Muscle Fatigue during Exercise

Authors: Seiler, Sarah E., Koves, Timothy R., Gooding, Jessica R., Wong, Kari E., Stevens, Robert D., Ilkayeva, Olga R., Wittmann, April H., DeBalsi, Karen L., Davies, Michael N., Lindeboom, Lucas, Schrauwen, Patrick, Schrauwen-Hinderling, Vera B., Muoio, Deborah M.

Source: In Cell Metabolism 7 July 2015 22(1):65-76

Targeted Metabolomics Connects Thioredoxin-interacting Protein (TXNIP) to Mitochondrial Fuel Selection and Regulation of Specific Oxidoreductase Enzymes in Skeletal Muscle

Authors: DeBalsi, Karen L., Wong, Kari E., Koves, Timothy R., Slentz, Dorothy H., Seiler, Sarah E., Wittmann, April H., Ilkayeva, Olga R., Stevens, Robert D., Perry, Christopher G.R., Lark, Daniel S., Hui, Simon T. ^**, Szweda, Luke, Neufer, P. Darrell, Muoio, Deborah M.

Source: In Journal of Biological Chemistry 14 March 2014 289(12):8106-8120

Targeted Expression of Human Vitamin D Receptor in Adipocytes Decreases Energy Expenditure and Induces Obesity in Mice

Authors: Wong, Kari E., Kong, Juan, Zhang, Wenshuo, Szeto, Frances L., Ye, Honggang, Deb, Dilip K., Brady, Matthew J., Li, Yan Chun

Source: In Journal of Biological Chemistry 30 September 2011 286(39):33804-33810

Metabolomic Profiles Associated With Blood Pressure Reduction in Response to the DASH and DASH-Sodium Dietary Interventions.

Authors: Kim, Hyunju, Appel, Lawrence J., Lichtenstein, Alice H., Wong, Kari E., Chatterjee, Nilanjan, Rhee, Eugene P., Rebholz, Casey M.

Source: Hypertension (0194911X); Jul2023, Vol. 80 Issue 7, p1494-1506, 13p

The Combination of a Human Biomimetic Liver Microphysiology System with BIOLOGXsym, a Quantitative Systems Toxicology (QST) Modeling Platform for Macromolecules, Provides Mechanistic Understanding of Tocilizumab- and GGF2-Induced Liver Injury.

Authors: Beaudoin, James J., Clemens, Lara, Miedel, Mark T., Gough, Albert, Zaidi, Fatima, Ramamoorthy, Priya, Wong, Kari E., Sarangarajan, Rangaprasad, Battista, Christina, Shoda, Lisl K. M., Siler, Scott Q., Taylor, D. Lansing, Howell, Brett A., Vernetti, Lawrence A., Yang, Kyunghee

Source: International Journal of Molecular Sciences; Jun2023, Vol. 24 Issue 11, p9692, 23p

Subject Terms: LIVER injuries, LIVER, TOXICOLOGY, TISSUE remodeling, MACROMOLECULES, BILE acids

Combined vitamin D analog and AT1 receptor antagonist synergistically block the development of kidney disease in a model of type 2 diabetes

Authors: Deb, Dilip K., Sun, Tao, Wong, Kari E., Zhang, Zhongyi, Ning, Gang, Zhang, Yan, Kong, Juan, Shi, Helen, Chang, Anthony, Li, Yan Chun ^*

Source: In Kidney International 1 June 2010 77(11):1000-1009

Whole-Genome Sequencing Analysis of Human Metabolome in Multi-Ethnic Populations.

Authors: Feofanova, Elena V., Brown, Michael R., Alkis, Taryn, Manuel, Astrid M., Li, Xihao, Tahir, Usman A., Li, Zilin, Mendez, Kevin M., Kelly, Rachel S., Qi, Qibin, Chen, Han, Larson, Martin G., Lemaitre, Rozenn N., Morrison, Alanna C., Grieser, Charles, Wong, Kari E., Gersztern, Robert E., Zhao, Zhongming, Lasky-Su, Jessica, Lin, Honghuang

Source: Nature Communications; 5/30/2023, Vol. 14 Issue 1, p1-12, 12p

Subject Terms: SEQUENCE analysis, GENETIC variation, X chromosome, NUCLEOTIDE sequencing, METABOLIC regulation, BLOOD proteins, EXOMES

1,25-Dihydroxyvitamin D3 Suppresses Renin Gene Transcription by Blocking the Activity of the Cyclic AMP Response Element in the Renin Gene Promoter

Authors: Yuan, Weihua, Pan, Wei, Kong, Juan, Zheng, Wei, Szeto, Frances L., Wong, Kari E., Cohen, Ronald, Klopot, Anna, Zhang, Zhongyi, Li, Yan Chun

Source: In Journal of Biological Chemistry 12 October 2007 282(41):29821-29830

Metabolomic Markers of Ultra-Processed Food and Incident CKD

Authors: Su, Donghan, Chen, Jingsha, Du, Shutong, Kim, Hyunju, Yu, Bing, Wong, Kari E., Boerwinkle, Eric, Rebholz, Casey M.

Source: Clinical Journal of The American Society of Nephrology; March 2023, Vol. 18 Issue: 3 p327-336, 10p

Butyrate-Producing Bacteria and Insulin Homeostasis: The Microbiome and Insulin Longitudinal Evaluation Study (MILES).

Authors: Cui, Jinrui, Ramesh, Gautam, Wu, Martin, Jensen, Elizabeth T., Crago, Osa, Bertoni, Alain G., Gao, Chunxu, Hoffman, Kristi L., Sheridan, Patricia A., Wong, Kari E., Wood, Alexis C., Chen, Yii-Der I., Rotter, Jerome I., Petrosino, Joseph F., Rich, Stephen S., Goodarzi, Mark O.

Source: Diabetes; Nov2022, Vol. 71 Issue 11, p2438-2446, 9p

Subject Terms: BLOOD sugar analysis, PHENOMENOLOGICAL biology, HOMEOSTASIS, RESEARCH funding, INSULIN, INSULIN resistance, TYPE 2 diabetes, MICROBIOLOGY, BUTYRIC acid

Involvement of the vitamin D receptor in energy metabolism: regulation of uncoupling proteins.

Authors: Wong, Kari E., Szeto, Frances L., Zhang, Wenshuo

Source: American Journal of Physiology; April 2009 pt1, Vol. 296 Issue 4, pE820-E828, 9p

Plasma Metabolites Associated with a Protein‐Rich Dietary Pattern: Results from the OmniHeart Trial.

Authors: Kim, Hyunju, Lichtenstein, Alice H., White, Karen, Wong, Kari E., Miller, Edgar R., Coresh, Josef, Appel, Lawrence J., Rebholz, Casey M.

Source: Molecular Nutrition & Food Research; Mar2022, Vol. 66 Issue 6, p1-11, 11p