ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells

Authors: Lambert, Arthur W., Fiore, Christopher, Chutake, Yogesh, Verhaar, Elisha R., Strasser, Patrick C., Chen, Mei Wei, Farouq, Daneyal, Das, Sunny, Li, Xin, Eaton, Elinor Ng, Zhang, Yun, Liu Donaher, Joana, Engstrom, Ian, Reinhardt, Ferenc, Yuan, Bingbing, Gupta, Sumeet, Wollison, Bruce, Eaton, Matthew, Bierie, Brian, Carulli, John, Olson, Eric R., Guenther, Matthew G., Weinberg, Robert A.

Source: In Developmental Cell 19 December 2022 57(24):2714-2730

Genomic profiling of a randomized trial of interferon-α vs hydroxyurea in MPN reveals mutation-specific responses

Authors: Knudsen, Trine Alma, Skov, Vibe, Stevenson, Kristen, Werner, Lillian, Duke, William, Laurore, Charles, Gibson, Christopher J., Nag, Anwesha, Thorner, Aaron R., Wollison, Bruce, Hansen, Dennis Lund, Ellervik, Christina, El Fassi, Daniel, de Stricker, Karin, Ocias, Lukas Frans, Brabrand, Mette, Bjerrum, Ole Weis, Overgaard, Ulrik Malthe, Frederiksen, Mikael, Kristensen, Thomas Kielsgaard, Kruse, Torben A., Thomassen, Mads, Mourits-Andersen, Torben, Severinsen, Marianne Tang, Stentoft, Jesper, Starklint, Joern, Neuberg, Donna S., Kjaer, Lasse, Larsen, Thomas Stauffer, Hasselbalch, Hans Carl ^*, Lindsley, R. Coleman ^*, Mullally, Ann ^{*, *}

Source: In Blood Advances 12 April 2022 6(7):2107-2119

ViroPanel: Hybrid Capture and Massively Parallel Sequencing for Simultaneous Detection and Profiling of Oncogenic Virus Infection and Tumor Genome

Authors: Slevin, Michael K., Wollison, Bruce M., Powers, Winslow, Burns, Robert T., Patel, Neil, Ducar, Matthew D., Starrett, Gabriel J., Garcia, Elizabeth P., Manning, Danielle K., Cheng, Jingwei, Hanna, Glenn J., Kaye, Kenneth M., Van Hummelen, Paul, Nag, Anwesha, Thorner, Aaron R., DeCaprio, James A., MacConaill, Laura E.

Source: In The Journal of Molecular Diagnostics April 2020 22(4):476-487

Low-level mosaicism in tuberous sclerosis complex: prevalence, clinical features, and risk of disease transmission

Authors: Giannikou, Krinio, Lasseter, Kathryn D., Grevelink, Joannes M., Tyburczy, Magdalena E., Dies, Kira A., Zhu, Zachary, Hamieh, Lana, Wollison, Bruce M., Thorner, Aaron R., Ruoss, Stephen J., Thiele, Elizabeth A., Sahin, Mustafa, Kwiatkowski, David J.

Source: In Genetics in Medicine November 2019 21(11):2639-2643

Recurrent genetic HLA loss in AML relapsed after matched unrelated allogeneic hematopoietic cell transplantation

Authors: Jan, Max, Leventhal, Matthew J., Morgan, Elizabeth A., Wengrod, Jordan C., Nag, Anwesha, Drinan, Samantha D., Wollison, Bruce M., Ducar, Matthew D., Thorner, Aaron R., Leppanen, Scott, Baronas, Jane, Stevens, Jonathan, Lane, William J., Kekre, Natasha, Ho, Vincent T., Koreth, John, Cutler, Corey S., Nikiforow, Sarah, Alyea, Edwin P., III, Antin, Joseph H., Soiffer, Robert J., Ritz, Jerome, Lindsley, R. Coleman, Ebert, Benjamin L.

Source: In Blood Advances 23 July 2019 3(14):2199-2204

ViroPanel

Authors: Slevin, Michael K., Wollison, Bruce M., Powers, Winslow, Burns, Robert T., Patel, Neil, Ducar, Matthew D., Starrett, Gabriel J., Garcia, Elizabeth P., Manning, Danielle K., Cheng, Jingwei, Hanna, Glenn J., Kaye, Kenneth M., Van Hummelen, Paul, Nag, Anwesha, Thorner, Aaron R., DeCaprio, James A., MacConaill, Laura E.

Source: Journal of molecular diagnostics. 22(4):476-487

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114065748.0x000001&indx=1&recIds=ETOCvdc_100114065748.0x000001

Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer

Authors: Yurgelun, Matthew B., Chittenden, Anu B., Morales-Oyarvide, Vicente, Rubinson, Douglas A., Dunne, Richard F., Kozak, Margaret M., Qian, Zhi Rong, Welch, Marisa W., Brais, Lauren K., Da Silva, Annacarolina, Bui, Justin L., Yuan, Chen, Li, Tingting, Li, Wanwan, Masuda, Atsuhiro, Gu, Mancang, Bullock, Andrea J., Chang, Daniel T., Clancy, Thomas E., Linehan, David C., Findeis-Hosey, Jennifer J., Doyle, Leona A., Thorner, Aaron R., Ducar, Matthew D., Wollison, Bruce M., Khalaf, Natalia, Perez, Kimberly, Syngal, Sapna, Aguirre, Andrew J., Hahn, William C., Meyerson, Matthew L., Fuchs, Charles S., Ogino, Shuji, Hornick, Jason L., Hezel, Aram F., Koong, Albert C., Nowak, Jonathan A., Wolpin, Brian M.

Source: In Genetics in Medicine January 2019 21(1):213-223

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

Authors: Townsend, Elizabeth C., Murakami, Mark A., Christodoulou, Alexandra, Christie, Amanda L., Köster, Johannes, DeSouza, Tiffany A., Morgan, Elizabeth A., Kallgren, Scott P., Liu, Huiyun, Wu, Shuo-Chieh, Plana, Olivia, Montero, Joan, Stevenson, Kristen E., Rao, Prakash, Vadhi, Raga, Andreeff, Michael, Armand, Philippe, Ballen, Karen K., Barzaghi-Rinaudo, Patrizia, Cahill, Sarah, Clark, Rachael A., Cooke, Vesselina G., Davids, Matthew S., DeAngelo, Daniel J., Dorfman, David M., Eaton, Hilary, Ebert, Benjamin L., Etchin, Julia, Firestone, Brant, Fisher, David C., Freedman, Arnold S., Galinsky, Ilene A., Gao, Hui, Garcia, Jacqueline S., Garnache-Ottou, Francine, Graubert, Timothy A., Gutierrez, Alejandro, Halilovic, Ensar, Harris, Marian H., Herbert, Zachary T., Horwitz, Steven M., Inghirami, Giorgio, Intlekofer, Andrew M., Ito, Moriko, Izraeli, Shai, Jacobsen, Eric D., Jacobson, Caron A., Jeay, Sébastien, Jeremias, Irmela, Kelliher, Michelle A., Koch, Raphael, Konopleva, Marina, Kopp, Nadja, Kornblau, Steven M., Kung, Andrew L., Kupper, Thomas S., LeBoeuf, Nicole R., LaCasce, Ann S., Lees, Emma, Li, Loretta S., Look, A. Thomas, Murakami, Masato, Muschen, Markus, Neuberg, Donna, Ng, Samuel Y., Odejide, Oreofe O., Orkin, Stuart H., Paquette, Rachel R., Place, Andrew E., Roderick, Justine E., Ryan, Jeremy A., Sallan, Stephen E., Shoji, Brent, Silverman, Lewis B., Soiffer, Robert J., Steensma, David P., Stegmaier, Kimberly, Stone, Richard M., Tamburini, Jerome, Thorner, Aaron R., van Hummelen, Paul, Wadleigh, Martha, Wiesmann, Marion, Weng, Andrew P., Wuerthner, Jens U., Williams, David A., Wollison, Bruce M., Lane, Andrew A., Letai, Anthony, Bertagnolli, Monica M., Ritz, Jerome, Brown, Myles, Long, Henry, Aster, Jon C., Shipp, Margaret A., Griffin, James D., Weinstock, David M.

Source: In Cancer Cell 11 April 2016 29(4):574-586

Perturbational phenotyping of human blood cells reveals genetically determined latent traits associated with subsets of common diseases

Authors: Homilius, Max, Zhu, Wandi, Eddy, Samuel S., Thompson, Patrick C., Zheng, Huahua, Warren, Caleb N., Evans, Chiara G., Kim, David D., Xuan, Lucius L., Nsubuga, Cissy, Strecker, Zachary, Pettit, Christopher J., Cho, Jungwoo, Howie, Mikayla N., Thaler, Alexandra S., Wilson, Evan, Wollison, Bruce, Smith, Courtney, Nascimben, Julia B., Nascimben, Diana N., Lunati, Gabriella M., Folks, Hassan C., Cupelo, Matthew, Sridaran, Suriya, Rheinstein, Carolyn, McClennen, Taylor, Goto, Shinichi, Truslow, James G., Vandenwijngaert, Sara, MacRae, Calum A., Deo, Rahul C.

Source: Nature Genetics; January 2024, Vol. 56 Issue: 1 p37-50, 14p

Blood collection in cell-stabilizing tubes does not impact germline DNA quality for pediatric patients.

Authors: Wollison, Bruce M.¹, Thai, Edwin¹, Mckinney, Aimee², Ward, Abigail³, Clapp, Andrea¹, Clinton, Catherine³, Nag, Anwesha¹, Thorner, Aaron R.¹, Gastier-Foster, Julie M.^2,4, Crompton, Brian D.^3,5 briand_crompton@dfci.harvard.edu

Source: PLoS ONE. 12/05/2017, Vol. 12 Issue 12, p1-11. 11p.

Subject Terms: *TUMORS in children, *NONINVASIVE diagnostic tests, *NUCLEOTIDE sequencing, *LEUKOCYTES, *CANCER cells, *MICROARRAY technology, *BLOOD collection

Correction: Low-level mosaicism in tuberous sclerosis complex: prevalence, clinical features, and risk of disease transmission

Authors: Giannikou, Krinio, Lasseter, Kathryn D., Grevelink, Joannes M., Tyburczy, Magdalena E., Dies, Kira A., Zhu, Zachary, Hamieh, Lana, Wollison, Bruce M., Thorner, Aaron R., Ruoss, Stephen J., Thiele, Elizabeth A., Sahin, Mustafa, Kwiatkowski, David J.

Source: In Genetics in Medicine October 2021 23(10):2022-2022

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Genomic Profiling of a Phase III Clinical Trial of Interferon Versus Hydroxyurea in MPN Patients Reveals Mutation-Specific and Treatment-Specific Patterns of Response

Authors: Knudsen, Trine Alma ^*, Skov, Vibe ^*, Werner, Lillian ^*, Duke, William ^*, Gibson, Christopher J., Nag, Anwesha ^*, Thorner, Aaron R. ^*, Wollison, Bruce ^*, Hansen, Dennis Lund ^*, Larsen, Thomas Stauffer ^*, Ellervik, Christina ^*, El Fassi, Daniel ^*, Stricker, Karin de ^*, Ocias, Lukas Frans ^*, Brabrand, Mette ^*, Bjerrum, Ole Weis ^*, Overgaard, Ulrik Malthe ^*, Frederiksen, Mikael ^*, Kristensen, Thomas Kielsgaard ^*, Kruse, Torben A ^*, Thomassen, Mads ^*, Mourits-Andersen, Torben ^*, Severinsen, Marianne Tang ^*, Stentoft, Jesper ^*, Starklint, Joern ^*, Møller, Peter ^*, Neuberg, Donna S, Kjær, Lasse ^*, Hasselbalch, Hans, Lindsley, R. Coleman, Mullally, Ann

Source: In Blood 13 November 2019 134 Supplement 1:4202-4202

Recurrent Genetic HLA Loss in Acute Myeloid Leukemia Relapsed after Matched Unrelated Allogeneic Hematopoietic Cell Transplant

Authors: Jan, Max, Leventhal, Matt J ^*, Morgan, Elizabeth A, Wengrod, Jordan Chase ^*, Nag, Anewsha ^*, Drinan, Samantha D ^*, Wollison, Bruce M ^*, Ducar, Matthew D. ^*, Thorner, Aaron R. ^*, Kekre, Natasha, Ho, Vincent T. ^*, Koreth, John, Cutler, Corey S., Nikiforow, Sarah, Alyea, Edwin P., III, Antin, Joseph H., Soiffer, Robert J., Ritz, Jerome, Lindsley, R. Coleman, Ebert, Benjamin L.

Source: In Blood 29 November 2018 132 Supplement 1:817-817

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Dissection of PIK3CA Aberration for Cervical Adenocarcinoma Outcomes.

Authors: Chung, Tony K. H., Doran, Graeme, Cheung, Tak-Hong, Yim, So-Fan, Yu, Mei-Yung, Worley Jr., Michael J., Elias, Kevin M., Thorner, Aaron R., Pedamallu, Chandra Sekhar, Ojesina, Akinyemi I., Lau, Kei-Man, Ducar, Matthew D., Wong, Raymond R. Y., Wang, Vivian W., Nag, Anwesha, Wollison, Bruce M., Dalgarno, Audrey, Lee, Jacqueline H. S., Yeung, Suet-Ying, Wong, Lo

Source: Cancers; Jul2021, Vol. 13 Issue 13, p3218-3218, 1p

Subject Terms: CERVICAL cancer treatment, GENETIC mutation, DNA, ONCOGENES, CERVICAL cancer, CANCER relapse, CANCER patients, GENETIC markers, GENOMICS, DESCRIPTIVE statistics, PREDICTION models, TUMOR markers, POLYMERASE chain reaction, BODY fluid examination, LONGITUDINAL method, DISEASE risk factors