Mitochondrial transporter expression patterns distinguish tumor from normal tissue and identify cancer subtypes with different survival and metabolism.

Authors: Wohlrab, Hartmut^1,2 (AUTHOR) hartmut_wohlrab@hms.harvard.edu, Signoretti, Sabina^3,4 (AUTHOR), Rameh, Lucia E.⁵ (AUTHOR), DeConti, Derrick K.⁶ (AUTHOR) ddeconti@hsph.harvard.edu, Hansen, Steen H.^2,4 (AUTHOR)

Source: Scientific Reports. 10/11/2022, Vol. 12 Issue 1, p1-14. 14p.

Subject Terms: *LUNGS, *BREAST, *RENAL cell carcinoma, *MITOCHONDRIAL membranes, *METABOLISM, *TISSUES, *MITOCHONDRIA

The human mitochondrial transport/carrier protein family. Nonsynonymous single nucleotide polymorphisms (nsSNPs) and mutations that lead to human diseases

Authors: Wohlrab, Hartmut

Source: In BBA - Bioenergetics 2006 1757(9):1263-1270

The human mitochondrial transport protein family: Identification and protein regions significant for transport function and substrate specificity

Authors: Wohlrab, Hartmut

Source: In BBA - Bioenergetics 2005 1709(2):157-168

Homodimeric Mitochondrial Phosphate Transport Protein. Transient Subunit/Subunit Contact Site between the Transport Relevant Transmembrane Helices A.

Authors: Phelps, Anne, Wohlrab, Hartmut

Source: Biochemistry; May 25 2004, Vol. 43 Issue 20, p6200-6207, 8p

Resonance Raman Investigations of Cytochrome c Conformational Change upon Interaction with the Membranes of Intact and Ca2+-Exposed Mitochondria.

Authors: Berezhna, Svitlana, Wohlrab, Hartmut, Champion, Paul M.

Source: Biochemistry; May 27 2003, Vol. 42 Issue 20, p6149-6158, 10p

Single replacement constructs of all hydroxyl, basic, and acidic amino acids identify new function and structure-sensitive regions of the mitochondrial phosphate transport protein.

Authors: Wohlrab, Hartmut, Annese, Vincent, Haefele, Amanda

Source: Biochemistry; March 5 2002, Vol. 41 Issue 9, p3254-3261, 8p

Novel inter- and intrasubunit contacts between transport-relevant residues of the homodimeric mitochondrial phosphate transport protein

Authors: Wohlrab, Hartmut

Source: In Biochemical and Biophysical Research Communications 2004 320(3):685-688

Replacements of basic and hydroxyl amino acids identify structurally and functionally sensitive regions of the mitochondrial phosphate transport protein.

Authors: Briggs, Christine, Mincone, Leesa, Wohlrab, Hartmut

Source: Biochemistry; April 20 1999, Vol. 38 Issue 16, p5096-5102, 7p

Purified mitochondrial phosphate transport protein. Improved proteoliposomes and some properties of the transport protein sulfhydryl group(s)

Authors: Wohlrab, Hartmut, Collins, Anne, Costello, Diane

Source: Biochemistry; March 13 1984, Vol. 23, p1057-1064, 8p

Yeast mitochondrial phosphate transport protein expressed in Escherichia coli. Site-directed mutations at threonine-43 and at a similar location in the second tandem repeat (Isoleucine-141)

Authors: Wohlrab, Hartmut, Briggs, Christine

Source: Biochemistry; August 16 1994, Vol. 33, p9372-9375, 4p

Cloning and characterization of the mitochondrial phosphate transport protein gene from the yeast Saccharomyces cerevisiae.

Authors: Phelps, Anne, Schobert, Christian T., Wohlrab, Hartmut

Source: Biochemistry; January 8 1991, Vol. 30, p248-252, 5p

Age-related changes in the flight muscle mitochondria from the blowfly sarcophaga bullata.

Authors: Wohlrab, Hartmut

Source: Journal of Gerontology; May 1976, Vol. 31, p257-263, 7p

The yeast mitochondrial transport proteins: new sequences and consensus residues, lack of direct relation between consensus residues and transmembrane helices, expression patterns of the transport protein genes, and protein–protein interactions with other proteins

Authors: Belenkiy, Roman, Haefele, Amanda, Eisen, Michael B., Wohlrab, Hartmut ^*

Source: In BBA - Biomembranes 2000 1467(1):207-218

Homodimeric intrinsic membrane proteins. Identification and modulation of interactions between mitochondrial transporter (carrier) subunits

Authors: Wohlrab, Hartmut

Source: In Biochemical and Biophysical Research Communications 2010 393(4):746-750

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Resonance Raman Investigations of Cytochrome c Conformational Change upon Interaction with the Membranes of Intact and Ca[sup 2+]-Exposed Mitochondria.

Authors: Berezhna, Svitlana, Wohlrab, Hartmut, Champion, Paul M.

Source: Biochemistry. 5/27/2003, Vol. 42 Issue 20, p6149. 10p. 11 Graphs.

Subject Terms: *CYTOCHROMES, *CONFORMATIONAL analysis, *RAMAN spectroscopy, *RESONANCE Raman effect

Mitochondrial Phosphate Transport Protein. Reversions of Inhibitory Conservative Mutations....

Authors: Phelps, Anne, Briggs, Christine, Haefele, Amanda, Mincone, Leesa, Ligeti, Erzebet, Wohlrab, Hartmut

Source: Biochemistry; 2/20/2001, Vol. 40 Issue 7, p2080, 7p, 1 Diagram, 3 Charts, 2 Graphs

PURIFICATION AND RECONSTITUTION OF THE MITOCHONDRIAL PHOSPHATE TRANSPORTER*.

Authors: Wohlrab, Hartmut

Source: Annals of the New York Academy of Sciences; 1980, Vol. 358 Issue 1, p364-367, 4p

Mitochondrial Transport (Carrier) Proteins. Homodimers and Heterodimers

Authors: Wohlrab, Hartmut

Source: In Biophysical Journal February 2009 96(3) Supplement 1:272a-273a

Manganese deficiency and transcriptional regulation of mitochondrial superoxide dismutase in hepatomas

Authors: Borrello, Silvia, De Leo, Maria Emilia, Wohlrab, Hartmut, Galeotti, Tommaso

Source: FEBS Letters; January 1992, Vol. 310 Issue: 3 p249-254, 6p