Expression profiles of the autism-related SHANK proteins in the human brain.

Authors: Woelfle, Sarah¹ (AUTHOR), Pedro, Maria T.² (AUTHOR), Wagner, Jan³ (AUTHOR), Schön, Michael¹ (AUTHOR) michael.schoen@uni-ulm.de, Boeckers, Tobias M.^1,4 (AUTHOR) tobias.boeckers@uni-ulm.de

Source: BMC Biology. 11/13/2023, Vol. 21 Issue 1, p1-22. 22p.

Subject Terms: *AUTISM spectrum disorders, *POSTSYNAPTIC density protein, *CENTRAL nervous system, *SCAFFOLD proteins, *BRAIN stem

CLARITY increases sensitivity and specificity of fluorescence immunostaining in long-term archived human brain tissue.

Authors: Woelfle, Sarah^1,2 (AUTHOR), Deshpande, Dhruva^3,4 (AUTHOR), Feldengut, Simone⁵ (AUTHOR), Braak, Heiko⁵ (AUTHOR), Del Tredici, Kelly⁵ (AUTHOR), Roselli, Francesco^6,7 (AUTHOR), Deisseroth, Karl^8,9,10 (AUTHOR), Michaelis, Jens³ (AUTHOR), Boeckers, Tobias M.^1,7 (AUTHOR), Schön, Michael¹ (AUTHOR) michael.schoen@uni-ulm.de

Source: BMC Biology. 5/24/2023, Vol. 21 Issue 1, p1-28. 28p.

Subject Terms: *SENSITIVITY & specificity (Statistics), *ALZHEIMER'S disease, *IMMUNOSTAINING, *IMMUNOGLOBULINS, *FLUORESCENCE, *MOLECULAR structure

Neuropeptide FF (NPFF)-positive nerve cells of the human cerebral cortex and white matter in controls, selected neurodegenerative diseases, and schizophrenia.

Authors: Wiesner, Diana, Feldengut, Simone, Woelfle, Sarah, Boeckers, Tobias M., Ludolph, Albert C., Roselli, Francesco, Del Tredici, Kelly

Source: Acta Neuropathologica Communications; 6/28/2024, Vol. 12 Issue 1, p1-22, 22p

Subject Terms: VOXEL-based morphometry, NEURONS, WHITE matter (Nerve tissue), CEREBRAL cortex, TEMPORAL lobe, NEURODEGENERATION, GRAY matter (Nerve tissue)

Shank2 identifies a subset of glycinergic neurons involved in altered nociception in an autism model.

Authors: Olde Heuvel, Florian, Ouali Alami, Najwa, Aousji, Oumayma, Pogatzki-Zahn, Esther, Zahn, Peter K., Wilhelm, Hanna, Deshpande, Dhruva, Khatamsaz, Elmira, Catanese, Alberto, Woelfle, Sarah, Schön, Michael, Jain, Sanjay, Grabrucker, Stefanie, Ludolph, Albert C., Verpelli, Chiara, Michaelis, Jens, Boeckers, Tobias M., Roselli, Francesco

Source: Molecular Autism; 6/14/2023, Vol. 14 Issue 1, p1-22, 22p

Subject Terms: AUTISM spectrum disorders, NEURONS, GLYCINE receptors, BEHAVIORAL assessment, SPINAL cord, AUTISM, CATAPLEXY

Layer-Specific Vesicular Glutamate Transporter 1 Immunofluorescence Levels Delineate All Layers of the Human Hippocampus Including the Stratum lucidum.

Authors: Woelfle, Sarah, Boeckers, Tobias M.

Source: Frontiers in Cellular Neuroscience; 12/9/2021, Vol. 15, p1-11, 11p

Subject Terms: GLUTAMATE transporters, HIPPOCAMPUS (Brain), DENTATE gyrus, IMMUNOFLUORESCENCE, ENTORHINAL cortex, CONFOCAL microscopy, PYRAMIDAL neurons

Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus.

Authors: Heise, Christopher, Schroeder, Jan C., Schoen, Michael, Halbedl, Sonja, Reim, Dominik, Woelfle, Sarah, Kreutz, Michael R., Schmeisser, Michael J., Boeckers, Tobias M.

Source: Frontiers in Cellular Neuroscience; 4/26/16, p1-12, 12p

Subject Terms: PROTEIN research, POSTSYNAPTIC density protein, CELL adhesion molecules, HIPPOCAMPUS (Brain), CYTOSKELETON